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Article ; Online: Toward Patient-Centered Healthcare Value.

Kini, Vinay / Michael Ho, P

Circulation. Cardiovascular quality and outcomes

2019 Volume 12, Issue 5, Page(s) e005801

MeSH term(s)	Aged ; Humans ; Myocardial Infarction ; Patient Readmission ; Patient-Centered Care
Language	English
Publishing date	2019-05-18
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2483197-9
ISSN	1941-7705 ; 1941-7713
ISSN (online)	1941-7705
ISSN	1941-7713
DOI	10.1161/CIRCOUTCOMES.119.005801
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Article ; Online: Cluster-randomized implementation trial of two facilitation strategies to implement a novel information and communications technology at the Veterans Health Administration

Chelsea Leonard / Evan Carey / Ariel Holstein / P. Michael Ho / Jeffrey T. Heckman

Implementation Science, Vol 19, Iss 1, Pp 1-

2024 Volume 12

Abstract: Abstract Background Information and communication technologies (ICTs) improve quality and efficiency of healthcare, but effective practices for implementing new ICTs are unknown. From 2019 to 2021, the Veterans Health Administration (VHA) implemented ... ...

Abstract	Abstract Background Information and communication technologies (ICTs) improve quality and efficiency of healthcare, but effective practices for implementing new ICTs are unknown. From 2019 to 2021, the Veterans Health Administration (VHA) implemented FLOW3, an ICT that facilitates prosthetic limb care. The goal of this study was to compare the impact of two facilitation strategies on FLOW3 adoption, implementation, and sustainment. Methods FLOW3 is a computerized workflow management system comprised of three applications that facilitate the three steps for prosthesis authorization. During VHA’s implementation of FLOW3, we randomized 60 VHA sites to basic or enhanced facilitation groups. Basic facilitation included a manualized training toolkit and office hours. Enhanced facilitation included basic facilitation plus monthly learning collaboratives and site-specific performance reports. Outcomes included time to adoption of FLOW3 and complete FLOW3 utilization rates during implementation and sustainment periods. We compared outcomes between sites assigned to basic versus enhanced facilitation groups. Results were calculated using both intent-to-treat (ITT) and dose–response analyses. The dose–response analysis used a per-protocol approach and required sites in the enhanced facilitation group to join two of six learning collaboratives; sites that attended fewer were reassigned to the basic group. Results Randomization assigned 30 sites to enhanced facilitation and 30 to basic. Eighteen of 30 randomized sites were included in the enhanced facilitation group for dose–response analysis. During the implementation period, enhanced facilitation sites were significantly more likely to completely utilize FLOW3 than basic facilitation sites (HR: 0.17; 95% CI: 1.18, 4.53, p = 0.02) based on ITT analysis. In the dose–response analysis, the enhanced group was 2.32 (95% CI: 1.18, 4.53) times more likely to adopt FLOW3 than basic group (p = 0.014). Conclusions Enhanced facilitation including a learning collaborative and ...
Keywords	Information and communication technology ; Implementation ; Facilitation ; Medicine (General) ; R5-920
Subject code	306
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Educational exposures associated with preclinical medical student interest in pursuing surgical residency: Longitudinal mixed-methods study with narrative evaluation.

Khondker, Adree / Lee, Michael Ho-Yan / Kangasjarvi, Emilia / Simpson, Jory S

Surgery open science

2023 Volume 12, Page(s) 43–47

Abstract: Introduction: Pre-clerkship medical students rely on various educational experiences to decide on the residency they would like to pursue. We conducted a longitudinal mixed-methods study to identify educational experiences in pre-clerkship that are ... ...

Abstract	Introduction: Pre-clerkship medical students rely on various educational experiences to decide on the residency they would like to pursue. We conducted a longitudinal mixed-methods study to identify educational experiences in pre-clerkship that are associated with an interest in pursuing surgery. Methods: Pre-clerkship medical students were invited to complete an initial survey regarding their interest in surgery and educational exposures. After 10 months, a follow-up survey was sent to identify changes in their interest and the role of educational experiences they may have had in the interim. Univariate regression was used to determine associations, and thematic analysis was done. Results: Data from 218 pre-clerkship students showed that shadowing (OR = 2.7), participation in technical workshops (OR = 5.1), having a mentor (OR = 4.6) and conducting surgical research (OR = 4.6) were associated with an interest in pursuing surgery. From the students with follow-up data, thematic analysis showed that 94 %, 89 %, and 81 % of students found shadowing, research, and mentorship, respectively, as influential in the decision of pursuing a surgical specialty, respectively. Conclusions: Shadowing and mentorship were important factors for students in the decision-making process in pursuing surgery. Identifying high-yield educational experiences-for students to determine if one wants to pursue a surgical specialty is important for educators in curriculum design for resource allocation. Key message: We describe a longitudinal mixed-methods study to determine the role of early educational exposures which influence a medical student's decision to pursue a surgical specialty. Shadowing, technical skills workshops, surgical mentorship, involvement in surgical research, play an important role for student decisions.
Language	English
Publishing date	2023-03-03
Publishing country	United States
Document type	Journal Article
ISSN	2589-8450
ISSN (online)	2589-8450
DOI	10.1016/j.sopen.2023.03.002
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Article ; Online: Toward the Design and Construction of Supramolecular Functional Molecular Materials Based on Metal-Metal Interactions.

Chan, Michael Ho-Yeung / Yam, Vivian Wing-Wah

Journal of the American Chemical Society

2022

Abstract: Supramolecular functional materials represent an emerging class of materials that have been governed by the supramolecular chemistry of self-assembled molecules. Such high-order molecular hierarchies have been stabilized by various kinds of noncovalent ... ...

Abstract	Supramolecular functional materials represent an emerging class of materials that have been governed by the supramolecular chemistry of self-assembled molecules. Such high-order molecular hierarchies have been stabilized by various kinds of noncovalent intermolecular forces including hydrogen bonding, electrostatic, donor-acceptor, π-π stacking interactions, and dispersion forces. Recently, metal-metal interactions have also emerged as an unconventional type of noncovalent interaction that is unique in the metal complex system for the construction of self-assembled metal-based materials. These metal-metal interactions have further imparted the self-assembled materials with rich spectroscopic functionalities. However, the systematic control of these hierarchical architectures through metal-metal interactions remains challenging. In this Perspective, we aim to stimulate research direction in the field with the utilization of such intriguing and unique directional noncovalent metal-metal interactions as one of the driving forces, highlighting the roles and significance of metal-metal interactions and ultimately facilitating a controlled and rational design and synthesis of metallosupramolecular functional materials with rich spectroscopic properties and huge potential for various applications.
Language	English
Publishing date	2022-12-09
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.2c08551
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Article ; Online: Exploring Medical Students' Perceptions of Peer-to-Peer Interactions Related to Applying to a Surgical Residency.

Lee, Michael Ho-Yan / Iyengar, Yajur / Budiansky, Dan / Veinot, Paula / Law, Marcus

Journal of surgical education

2023 Volume 81, Issue 2, Page(s) 193–201

Abstract: Objective: The objectives were to (1) identify themes related to competitive peer-to-peer interactions elicited from the lived experiences of undergraduate medical students, and (2) understand how these experiences influenced medical students' choices ... ...

Abstract	Objective: The objectives were to (1) identify themes related to competitive peer-to-peer interactions elicited from the lived experiences of undergraduate medical students, and (2) understand how these experiences influenced medical students' choices related to surgical residency programs. Design: A qualitative descriptive methodology, with purposive and maximal variation sampling (e.g., selection based on medical school location; gender), was adopted for this study. Setting: Temerty Faculty of Medicine, University of Toronto. Participants: Participants were 15 undergraduate medical students from 4 medical schools in Ontario, Canada, who agreed to an individual semi-structured interview by Zoom or telephone. Results: Peer-to-peer interactions influence students' perception of self and identity formation related to surgical specialty decision-making and interest. These interactions were shown to hold greater value, specifically for information gathering. Identity formation, related to pursuing a surgical residency, was influenced by the attitudes and perceptions of competition with peers throughout medical school. Cultures of competition were seen to dictate peer-to-peer interactions and their associated value, with their perception and experience differing between medical schools. Conclusions: Peer-to-peer interactions and a culture of competition have inherent roles in the residency decision-making process. We observed that student background and pre-formed relationships influenced how students perceived and responded to competition. Addressing the culture of competitiveness associated with peer-to-peer interactions along with considering student background and pre-existing relationships may provide insight into how medical educators can tailor learning experiences that limit the detrimental effects of hidden curriculum influences.
MeSH term(s)	Humans ; Students, Medical ; Internship and Residency ; Ontario ; Peer Group ; Attitude ; Curriculum ; Education, Medical, Undergraduate/methods
Language	English
Publishing date	2023-12-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2277538-9
ISSN	1878-7452 ; 1931-7204
ISSN (online)	1878-7452
ISSN	1931-7204
DOI	10.1016/j.jsurg.2023.11.007
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Article ; Online: Recent Approaches to Improve Medication Adherence in Patients with Coronary Heart Disease: Progress Towards a Learning Healthcare System.

Levy, Andrew E / Huang, Carrie / Huang, Allen / Michael Ho, P

Current atherosclerosis reports

2018 Volume 20, Issue 1, Page(s) 5

Abstract: Purpose of review: Non-adherence to medications for the secondary prevention of myocardial infarction (MI) is a major contributor to morbidity and mortality in these patients. This review describes recent advances in promoting adherence to therapies for ...

Abstract	Purpose of review: Non-adherence to medications for the secondary prevention of myocardial infarction (MI) is a major contributor to morbidity and mortality in these patients. This review describes recent advances in promoting adherence to therapies for coronary artery disease (CAD). Recent findings: Two large randomized controlled trials to "incentivize" adherence were somewhat disappointing; neither financial incentives nor "peer pressure" successfully increased rates of adherence in the post-MI population. Patient education and provider engagement appear to be critical aspects of improving adherence to CAD therapies, where the provider is a physician, pharmacist, or nurse and follow-up is performed in person or by telephone. Fixed-dose combinations of CAD medications, formulated as a so-called "polypill," have shown some early efficacy in increasing adherence. Technological advances that automate monitoring and/or encouragement of adherence are promising but seem universally dependent on patient engagement. For example, medication reminders via text message perform better if patients are required to respond. Multifaceted interventions, in which these and other interventions are combined together, appear to be most effective. There are several available types of proven interventions through which providers, and the health system at large, can advance patient adherence to CAD therapies. No single intervention to promote adherence will be successful in all patients. Further study of multifaceted interventions and the interactions between different interventions will be important to advancing the field. The goal is a learning healthcare system in which a network of interventions responds and adapts to patients' needs over time.
MeSH term(s)	Cardiovascular Agents/therapeutic use ; Coronary Artery Disease/complications ; Coronary Artery Disease/drug therapy ; Coronary Disease/complications ; Coronary Disease/drug therapy ; Humans ; Medication Adherence/psychology ; Myocardial Infarction/etiology ; Myocardial Infarction/prevention & control ; Patient Education as Topic ; Professional Role ; Professional-Patient Relations ; Randomized Controlled Trials as Topic ; Reminder Systems ; Secondary Prevention
Chemical Substances	Cardiovascular Agents
Language	English
Publishing date	2018-01-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	2057369-8
ISSN	1534-6242 ; 1523-3804
ISSN (online)	1534-6242
ISSN	1523-3804
DOI	10.1007/s11883-018-0707-0
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Article ; Online: Structural Damage Detection and Health Monitoring

Gangbing Song / Siu Chun Michael Ho / Qingzhao Kong

Applied Sciences, Vol 9, Iss 19, p

2019 Volume 4027

Abstract: Readers who have recently visited or purchased a newly built house may have started to notice the standard inclusion of “smart home” technologies [.] ...

Abstract	Readers who have recently visited or purchased a newly built house may have started to notice the standard inclusion of “smart home” technologies [.]
Keywords	n/a ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Language	English
Publishing date	2019-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Stimuli-Responsive Two-Dimensional Supramolecular Polymers Based on Trinuclear Platinum(II) Scaffolds: Reversible Modulation of Photoluminescence, Cavity Size, and Water Permeability.

Chen, Zhen / Chan, Michael Ho-Yeung / Yam, Vivian Wing-Wah

Journal of the American Chemical Society

2020 Volume 142, Issue 38, Page(s) 16471–16478

Abstract: Here we report the first two-dimensional (2D) supramolecular polymer, which has varying structure and function arising from the perturbation of noncovalent metal···metal interactions in response to acid-base stimuli. This 2D assembly possesses a ... ...

Abstract	Here we report the first two-dimensional (2D) supramolecular polymer, which has varying structure and function arising from the perturbation of noncovalent metal···metal interactions in response to acid-base stimuli. This 2D assembly possesses a positively charged, honeycomb-like nanostructure consisting of trinuclear alkynylplatinum(II) terpyridine complexes appended with acid-sensitive dimethylamino groups. Upon addition of acids and bases, reversible switching mediated by protonation and deprotonation of dimethylamino and dimethylammonium moieties intrinsically alters the positive charge density of the constituent cationic units, which causes interior cavities to adaptively adjust their size, accompanied by drastic photoluminescence changes. When water molecules pass through the membranes obtained from 2D supramolecular polymers, the permeating flux can also be tuned by the pH values of the buffer media. This work paves the way toward supramolecularly engineered 2D smart materials with stimuli-responsive properties.
Language	English
Publishing date	2020-09-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.0c07969
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Article ; Online: Phosphorescent Cyclometalated Platinum(II) Enantiomers with Circularly Polarized Luminescence Properties and Their Assembly Behaviors.

Li, Baoning / Li, Yongguang / Chan, Michael Ho-Yeung / Yam, Vivian Wing-Wah

Journal of the American Chemical Society

2021 Volume 143, Issue 51, Page(s) 21676–21684

Abstract: Platinum(II) complexes as supramolecular luminescent materials have received considerable attention due to their unique planar structures and fascinating photophysical properties. However, the molecular design of platinum(II) complexes with impressive ... ...

Abstract	Platinum(II) complexes as supramolecular luminescent materials have received considerable attention due to their unique planar structures and fascinating photophysical properties. However, the molecular design of platinum(II) complexes with impressive circularly polarized luminescence properties still remains challenging and rarely explored. Herein, we reported a series of cyclometalated platinum(II) complexes with benzaldehyde and its derived imine-containing alkynyl ligands to investigate their phosphorescent, chiroptical, and self-assembly behaviors. An isodesmic growth mechanism is found for their temperature-dependent self-assembly process. The chiral sense of the enantiomers can be transferred from the chiral alkynyl ligands to the cyclometalated platinum(II) dipyridylbenzene N^C^N chromophore and further amplified through supramolecular assembly via intermolecular noncovalent interactions. Notably, distinctive phosphorescent properties and nanostructured morphologies have been found for enantiomers
Language	English
Publishing date	2021-12-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.1c10943
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Article ; Online: Testing surge capacity-A Canadian COVID-19 experience, Ontario's surge capacity for the first wave.

Lee, Michael Ho-Yan / Xu, Grace / Cheng, Fanny / Khalid, Ahmad Firas

Health policy (Amsterdam, Netherlands)

2021 Volume 125, Issue 10, Page(s) 1291–1296

Abstract: As of September 1st 2020, over 42 000 COVID-19 cases and 2 800 COVID-19-related deaths have been confirmed in Ontario, Canada. Testing enables quick identification of cases, which results in effective contact tracing and containment of virus spread. ... ...

Abstract	As of September 1st 2020, over 42 000 COVID-19 cases and 2 800 COVID-19-related deaths have been confirmed in Ontario, Canada. Testing enables quick identification of cases, which results in effective contact tracing and containment of virus spread. Faced with a lack of surge capacity in the public health laboratory system at the start, health officials implemented changes to testing and laboratory infrastructure to significantly expand testing capacity to include 1) the centralization of resources; and 2) the integration of private and independent labs into the COVID-19 testing program. With these changes, testing capacity has grown from approximately 4,000/day in March to 32,000/day by the end of August, 2020. Eligibility criteria for testing has expanded to increase sensitivity and include testing of asymptomatic individuals. Along with previous outbreaks, the COVID-19 pandemic has highlighted the need for integration of testing surge capacity in public health systems before outbreaks occur. This paper details the development and implementation of a COVID-19 testing program in Ontario from January 2020 to September 2020 during the first-wave of the pandemic. The goal of this analysis is to explore the historical precedence, present influences, and future implications of the program.
MeSH term(s)	COVID-19 ; COVID-19 Testing ; Humans ; Ontario ; Pandemics ; SARS-CoV-2 ; Surge Capacity
Language	English
Publishing date	2021-08-11
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605805-x
ISSN	1872-6054 ; 0168-8510
ISSN (online)	1872-6054
ISSN	0168-8510
DOI	10.1016/j.healthpol.2021.08.001
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