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  1. Article: Pulsed Dye Laser for Treatment of Basal Cell Carcinoma.

    Baran, Kelsey L / Cheung, Tiffany C / Csank, George A / Michaels, Basil M

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 3, Page(s) e4850

    Abstract: Basal cell carcinoma (BCC) is the most common malignancy worldwide. The incidence of BCC is increasing up to 10% per year worldwide. Surgical excision and Mohs surgery are the gold standard treatment modalities. However, patients may not be candidates ... ...

    Abstract Basal cell carcinoma (BCC) is the most common malignancy worldwide. The incidence of BCC is increasing up to 10% per year worldwide. Surgical excision and Mohs surgery are the gold standard treatment modalities. However, patients may not be candidates for surgery. Pulsed dye laser (PDL) is a novel technique for treating BCC.
    Methods: Patients with biopsy-proven BCC underwent two treatments with PDL at 6-week intervals at Berkshire Cosmetic and Reconstructive Surgery Center. Patients returned 6 weeks after the second treatment for evaluation for response to treatment. Follow-up examinations were conducted at 6, 12, and 18 months after treatment with PDL.
    Results: Twenty patients with 21 biopsy-proven BCCs were treated with PDL at Berkshire Cosmetic and Reconstructive Surgery Center between 2019 and 2021. Nineteen BCCs had a complete response after two treatments, for a clearance rate of 90%. Two of the 21 lesions did not respond for an incomplete response rate of 10%.
    Conclusion: PDL is an effective nonsurgical treatment option in the management of BCC.
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000004850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Is Nicotine Replacement a Safe Alternative to Smoking in Plastic Surgery Patients?

    Michaels, Basil M / Craft, Patrick / Michaels, Julian A / Csank, George A

    Plastic and reconstructive surgery. Global open

    2018  Volume 6, Issue 12, Page(s) e2017

    Abstract: Background: E-cigarettes, nicotine transdermal patches, and nicotine chewing gum are occasionally used as cigarette replacements by patients, but it is unknown if their use is a safe alternative to smoking in the perioperative period.: Methods: All ... ...

    Abstract Background: E-cigarettes, nicotine transdermal patches, and nicotine chewing gum are occasionally used as cigarette replacements by patients, but it is unknown if their use is a safe alternative to smoking in the perioperative period.
    Methods: All patients undergoing major surgery at a single outpatient ambulatory surgery center for a 5-year period were tested for urine cotinine, a nicotine metabolite, the day of surgery. Patients were divided into 4 groups: never smoked (group A), quit smoking with negative urine test (group B), continued to smoke (group C), and quit smoking with positive urine test (group D). Statistical significance of complications among groups was tested using right tailed chi-square test and point biserial correlation coefficient calculations. To control for confounding factors, age and BMI of each group were compared using unequal sample size and variance
    Results: Four hundred seventy patients were included in the study. Patient count in each group was group A n = 380, group B n = 48, group C n = 32, and group D n = 10. Complication frequency was as follows D > C > A > B. Statistically significant differences were observed between D + C (cotinine positive) and A + B (cotinine negative)
    Conclusions: Nicotine replacement carries similar risks as continued smoking and is not as safe as abstinence in the perioperative period in plastic surgery patients. Importantly, patients who stopped smoking for the surgery had equivalent risk for postoperative complications as patients who had never smoked.
    Language English
    Publishing date 2018-12-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000002017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Outpatient abdominoplasty facilitated by rib blocks.

    Michaels, Basil M / Eko, Frederick N

    Plastic and reconstructive surgery

    2009  Volume 124, Issue 2, Page(s) 635–642

    Abstract: Background: Striving to increase patient comfort and feasibility of performing abdominoplasties as outpatient procedures, investigators have been exploring alternative methods of anesthesia to safely avoid general anesthesia. These techniques may result ...

    Abstract Background: Striving to increase patient comfort and feasibility of performing abdominoplasties as outpatient procedures, investigators have been exploring alternative methods of anesthesia to safely avoid general anesthesia. These techniques may result in decreased narcotic administration, and decreased postoperative nausea and vomiting. The authors have added the use of preoperative local anesthesia rib blocks with sedation to replace general anesthesia in abdominoplasties.
    Methods: All cases of abdominoplasty performed by the senior author (B.M.M.) were reviewed from 1999 to 2006 and divided into two groups. Group 1 was composed of 39 operations performed using general anesthesia. Group 2 was composed of 29 operations performed using rib blocks placed by the surgeon and supplemented by intravenous sedation. Chart review collected data on time in the operating and recovery rooms, use of narcotics and antiemetics, frequency of postoperative nausea and vomiting, and patient-reported pain. Possible confounding factors, additional procedures, anesthetic and surgical complications, and the need for hospitalization were also recorded. Statistical analysis with two-tailed Mann-Whitney and chi-square testing was used to reject the null hypothesis when comparing the two groups.
    Results: Statistically significant decreases in recovery room time, postoperative narcotics, postoperative nausea and vomiting, and pain were achieved using rib blocks. All other measures were similar for both groups. There were no hospitalizations, pneumothoraxes, major complications or deaths.
    Conclusion: Rib blocks placed before the start of surgery result in decreased recovery room times, pain, and postoperative nausea and vomiting, achieving increased patient comfort and feasibility of performing abdominoplasties in the outpatient setting.
    MeSH term(s) Abdomen/surgery ; Adipose Tissue/surgery ; Adult ; Ambulatory Surgical Procedures ; Anesthesia, General ; Body Mass Index ; Conscious Sedation ; Female ; Humans ; Middle Aged ; Nerve Block/methods ; Postoperative Nausea and Vomiting/epidemiology ; Postoperative Nausea and Vomiting/prevention & control ; Ribs
    Language English
    Publishing date 2009-06-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0b013e3181addbd7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prospective randomized comparison of onabotulinumtoxinA (Botox) and abobotulinumtoxinA (Dysport) in the treatment of forehead, glabellar, and periorbital wrinkles.

    Michaels, Basil M / Csank, George A / Ryb, Gabriel E / Eko, Frederick N / Rubin, Abigail

    Aesthetic surgery journal

    2012  Volume 32, Issue 1, Page(s) 96–102

    Abstract: Background: There are several commercially available neurotoxins to improve facial aesthetics, but few prospective, randomized trials have been conducted without commercial support to compare these agents.: Objectives: The authors present the results ...

    Abstract Background: There are several commercially available neurotoxins to improve facial aesthetics, but few prospective, randomized trials have been conducted without commercial support to compare these agents.
    Objectives: The authors present the results of a study examining and comparing the effects of onabotulinumtoxinA (BoNT-ONA; Botox, Allergan, Inc., Irvine, California) and abobotulinumtoxinA (BoNT-ABO; Dysport, Ipsen Ltd, Slough, UK).
    Methods: The authors enrolled 53 patients in a prospective, randomized trial in which each patient received a dose of BoNT-ONA on one side of the upper face and BoNT-ABO on the other. The effects of each agent were monitored and recorded over 150 days according to each patient's ability to elevate the brow, wrinkle count (as measured by the Visia system; Canfield Imaging Systems, Fairfield, New Jersey), and assessment of Fitzpatrick wrinkle scale rankings by blinded graders.
    Results: Results showed no statistically significant differences between the two agents. Both agents yielded measurable improvements on wrinkles of the upper face at 150 days.
    Conclusions: At the current pricing of the agents, BoNT-ABO offers a significant cost savings over BoNT-ONA, with a comparable efficacy. The effect of both drugs appears to be more prolonged than indicated in the current manufacturer guidelines.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Botulinum Toxins, Type A/therapeutic use ; Double-Blind Method ; Female ; Forehead ; Humans ; Injections ; Male ; Middle Aged ; Neuromuscular Agents/therapeutic use ; Orbit ; Prospective Studies ; Skin Aging/drug effects ; Treatment Outcome
    Chemical Substances Neuromuscular Agents ; onabotulinumtoxinA (E211KPY694) ; Botulinum Toxins, Type A (EC 3.4.24.69) ; abobotulinumtoxinA (EC 3.4.24.69)
    Language English
    Publishing date 2012-01
    Publishing country England
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1177/1090820X11430685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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