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  1. Article: Laparoscopic Cholecystectomy with Freehand Laparoscopic Camera Controller.

    Sapalidis, K / Michalopoulos, N / Mantalovas, S / Kesisoglou, I

    Current health sciences journal

    2017  Volume 43, Issue 2, Page(s) 159–162

    Abstract: Introduction: Free hand laparoscopic camera controller (FHLCC) is a new innovative robotic device that has been recently implemented and adopted in laparoscopic surgery, providing the surgeon more comfort in carrying out his surgical skills without the ... ...

    Abstract Introduction: Free hand laparoscopic camera controller (FHLCC) is a new innovative robotic device that has been recently implemented and adopted in laparoscopic surgery, providing the surgeon more comfort in carrying out his surgical skills without the difficulties related to the mutual understanding of the movements of the camera.
    Case presentation: We report the first case of laparoscopic cholecystectomy performed in our hospital with the aid of the free hand laparoscopic camera controller.
    Conclusion: Free hand laparoscopic camera controller provides the surgeon comfort in carrying out his surgical skills without the difficulties related to the mutual understanding of the movements of the camera. It combines the benefits of minimally invasive and robotic assisted surgery, increases efficiencies and improves patient recovery times.
    Language English
    Publishing date 2017-06-29
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.43.02.09
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  2. Article ; Online: Simple method for removing DOACs from plasma samples.

    Exner, T / Michalopoulos, N / Pearce, J / Xavier, R / Ahuja, M

    Thrombosis research

    2018  Volume 163, Page(s) 117–122

    Abstract: Aim: To evaluate a simple method using an adsorbent product (DOAC Stop) for extracting direct oral anti-coagulants (DOACs) from plasmas.: Method: DOAC Stop was tested on normal and a range of abnormal plasmas initially using activated partial ... ...

    Abstract Aim: To evaluate a simple method using an adsorbent product (DOAC Stop) for extracting direct oral anti-coagulants (DOACs) from plasmas.
    Method: DOAC Stop was tested on normal and a range of abnormal plasmas initially using activated partial thromboplastin time (APTT) tests and a more DOAC-sensitive Russells viper venom-based clotting test (DOAC Test). Further tests for prothrombin time/International Normalized Ratio (PT/INR), lupus anticoagulants, activated protein C (APC) resistance, antithrombin, plasminogen, protein C and S were carried out on various patient samples.
    Results: DOAC Stop was found to remove all types of DOACs including dabigatran, apixaban, rivaroxaban and edoxaban from test plasmas with minimal effect on any of the (mainly clotting) tests considered in this study.
    Summary: DOAC Stop can be used to identify plasmas containing DOAcs using simple clotting tests. It reduces the false positivity for lupus anticoagulants observed in dilute Russells viper venom time (dRVVT) tests on DOAC-containing plasmas and could be useful for eliminating unwanted effects of DOACs on routine coagulation testing.
    MeSH term(s) Administration, Oral ; Anticoagulants/blood ; Anticoagulants/therapeutic use ; Humans
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2018-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121852-9
    ISSN 1879-2472 ; 0049-3848
    ISSN (online) 1879-2472
    ISSN 0049-3848
    DOI 10.1016/j.thromres.2018.01.047
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 863: Show issues Location:
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  3. Article ; Online: Reliability and Concurrent Validity of the SARC-F and Its Modified Versions: A Systematic Review and Meta-Analysis.

    Voelker, Stefanie N / Michalopoulos, Nikolaos / Maier, Andrea B / Reijnierse, Esmee M

    Journal of the American Medical Directors Association

    2021  Volume 22, Issue 9, Page(s) 1864–1876.e16

    Abstract: Objectives: Sarcopenia, being prevalent in up to 40% of older adults, is associated with adverse health outcomes. The international sarcopenia guidelines recommend screening for sarcopenia using the SARC-F. A previous meta-analysis (2017) reported poor ... ...

    Abstract Objectives: Sarcopenia, being prevalent in up to 40% of older adults, is associated with adverse health outcomes. The international sarcopenia guidelines recommend screening for sarcopenia using the SARC-F. A previous meta-analysis (2017) reported poor validity of the SARC-F among community-dwelling older adults. Since then, modified SARC-F versions were developed and new sarcopenia definitions were published, including the SARC-F for case-finding. This systematic review and meta-analysis aimed to assess the reliability of the SARC-F and its concurrent validity to identify sarcopenia.
    Design: Systematic review and meta-analyses.
    Setting and participants: Adults (all ages) from any study population.
    Methods: A systematic search was conducted in MEDLINE, EMBASE, Cochrane, and CINAHL (January 1, 2013, to April 6, 2020). Articles were included if they reported on the reliability and/or concurrent validity of the (modified) SARC-F. No restrictions were applied for sex, age, study population, or sarcopenia definition. Reliability measures included inter-rater reliability, test-retest reliability, and internal consistency. Meta-analyses were performed for concurrent validity.
    Results: The 29 included articles included 21,855 individuals (mean age of 63.3±14.6 years, 61.3% females) among community-dwelling (n = 16), geriatric inpatient (n = 5), geriatric outpatient (n = 2), nursing home (n = 2), and long-term care (n = 1) populations. The SARC-F had good (2/4 articles) to excellent (2/4 articles) inter-rater reliability, moderate (1/6 articles) to good (5/6 articles) test-retest reliability, and low (4/8 articles) to high (4/8 articles) internal consistency. The SARC-F had low to moderate sensitivity (28.9%-55.3%) and moderate to high specificity (68.9%-88.9%) according to the European Working Group on Sarcopenia in Older People (EWGSOP; n = 13), revised EWGSOP definition (EWGSOP2; n = 6), Asian Working Group for Sarcopenia (AWGS; n = 13), Foundation for the National Institutes of Health (FNIH; n = 8), International Working Group on Sarcopenia (IWGS; n = 9), and Society on Sarcopenia, Cachexia and Wasting Disorders (n = 2). The SARC-CalF had low to moderate sensitivity (45.9%-57.2%) and high specificity (87.7%-91.3%) according to the EWGSOP (n = 5), AWGS (n = 4), FNIH (n = 3), and IWGS (n = 3).
    Conclusions and implications: Despite the good reliability of the SARC-F, its low to moderate sensitivity and moderate to high specificity make it nonoptimal to use for sarcopenia screening. It is recommended to apply the diagnostic criteria for sarcopenia without screening.
    MeSH term(s) Aged ; Cross-Sectional Studies ; Female ; Geriatric Assessment ; Humans ; Independent Living ; Male ; Mass Screening ; Middle Aged ; Reproducibility of Results ; Sarcopenia/diagnosis ; Sarcopenia/epidemiology ; Surveys and Questionnaires
    Language English
    Publishing date 2021-06-16
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ZDB-ID 2171030-2
    ISSN 1538-9375 ; 1525-8610
    ISSN (online) 1538-9375
    ISSN 1525-8610
    DOI 10.1016/j.jamda.2021.05.011
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5971: Show issues Location:
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  4. Article: High Intratumoral i-tRF-Gly

    Christodoulou, Spyridon / Katsaraki, Katerina / Vassiliu, Panteleimon / Danias, Nikolaos / Michalopoulos, Nikolaos / Tzikos, Georgios / Sideris, Diamantis C / Arkadopoulos, Nikolaos

    Biomedicines

    2023  Volume 11, Issue 7

    Abstract: Colorectal cancer (CRC), one of the most prevalent types of cancer, requires the discovery of new tumor biomarkers for accurate patient prognosis. In this work, the prognostic value of the tRNA fragment i-tRF- ... ...

    Abstract Colorectal cancer (CRC), one of the most prevalent types of cancer, requires the discovery of new tumor biomarkers for accurate patient prognosis. In this work, the prognostic value of the tRNA fragment i-tRF-Gly
    Language English
    Publishing date 2023-07-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11071945
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  5. Article: Lymph node mapping helps in R0 resection for anaplastic thyroid carcinoma-report of a case with prolonged survival.

    Karanikas, Michael / Michalopoulos, Nicolaos / Kofina, Konstantinia / Laskou, Styliani / Kteniadakis, Nektarios

    Journal of surgical case reports

    2019  Volume 2019, Issue 6, Page(s) rjz197

    Abstract: Anaplastic thyroid carcinoma is a rare tumor, consisting 1-2% of all thyroid malignancies and presenting a high mortality rate. Median survival for patients undergoing primary surgery is approximately 6.6 months. We present a case of a patient treated ... ...

    Abstract Anaplastic thyroid carcinoma is a rare tumor, consisting 1-2% of all thyroid malignancies and presenting a high mortality rate. Median survival for patients undergoing primary surgery is approximately 6.6 months. We present a case of a patient treated with R0 resection, including total thyroidectomy and lymphadenectomy of levels III, IV, VI and VII after cervical lymph node mapping, oral 131I administration, and radiotherapy. Proper preoperative research, R0 resection and relatively early diagnosis, led to good prognosis, as the patient is currently totally disease-free, twelve months postoperatively.
    Language English
    Publishing date 2019-06-20
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjz197
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  6. Article: Minimally Invasive Video-Assisted Total Thyroidectomy (mi V.A.T.T.) - Case Series of 48 Patients.

    Sapalidis, K / Mylonas, K S / Kotidis, E / Michalopoulos, N / Anastasiadis, I / Kanellos, I D

    Current health sciences journal

    2016  Volume 42, Issue 1, Page(s) 40–46

    Abstract: Purpose: The first report of miVATT was published in 1998 by Miccoli, leading to a revolution in the field of thyroid surgery. This prospective study aims to evaluate the technique with regard to our department's experience over a four-year period.: ... ...

    Abstract Purpose: The first report of miVATT was published in 1998 by Miccoli, leading to a revolution in the field of thyroid surgery. This prospective study aims to evaluate the technique with regard to our department's experience over a four-year period.
    Material-methods: Between September 2009 and October 2013, 48 adult patients (37 females, 11 males) with a mean age of 41.3 (± 11.6) years underwent scheduled miVATT for benign thyroid lesions. Selection criteria included thyroid volume <15 ml and nodules not exceeding 3.5 cm of diameter. Thyroiditis, previous neck surgery and previous irradiation, mediastinal goiter and involvement in another clinical study constituted the exclusion criteria. The procedure we performed was miVATT as described by Miccoli with the only additions being the use of the Harmonic Scalpel and the fixation of the endoscope on a holding device. Also, no drains were applied.
    Results: No conversions to open surgery were needed. Operation time for total thyroidectomy was 71.23 min (± 23.81) with a mean hospitalization of 1.14 days (± 0.4). Five patients (10.4%) exhibited transient hypocalcemia, whereas there were no recurrent laryngeal nerve palsies. Post-operative pain was mild and the final aesthetic result was considered excellent by the patients.
    Conclusion: miVATT is a safe and feasible alternative to the conventional thyroidectomy when performed in carefully selected patients by experienced surgeons.
    Language English
    Publishing date 2016-03-29
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.42.01.06
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  7. Article ; Online: Long-Term Manometric Impact of the Adjustable Gastric Band on Esophageal Motility: a Prospective Case-Control Study.

    Triantafyllou, Tania / Eleftheriou, Malvina Maria / Theodoropoulos, Charalampos / Schizas, Dimitrios / Michalopoulos, Nikolaos / Archontovasilis, Fotios / Theodorou, Dimitrios

    Obesity surgery

    2021  Volume 31, Issue 7, Page(s) 3333–3336

    MeSH term(s) Case-Control Studies ; Esophageal Motility Disorders/surgery ; Gastroplasty/adverse effects ; Humans ; Laparoscopy ; Manometry ; Obesity, Morbid/surgery ; Prospective Studies
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Letter
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-021-05361-6
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    Zs.A 3381: Show issues Location:
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  8. Article ; Online: The Minimum Effective Training Dose Required for 1RM Strength in Powerlifters.

    Androulakis-Korakakis, Patroklos / Michalopoulos, Nick / Fisher, James P / Keogh, Justin / Loenneke, Jeremy P / Helms, Eric / Wolf, Milo / Nuckols, Greg / Steele, James

    Frontiers in sports and active living

    2021  Volume 3, Page(s) 713655

    Abstract: The aim of this multi-experiment paper was to explore the concept of the minimum effective training dose (METD) required to increase 1-repetition-maximum (1RM) strength in powerlifting (PL) athletes. The METD refers to the least amount of training ... ...

    Abstract The aim of this multi-experiment paper was to explore the concept of the minimum effective training dose (METD) required to increase 1-repetition-maximum (1RM) strength in powerlifting (PL) athletes. The METD refers to the least amount of training required to elicit meaningful increases in 1RM strength. A series of five studies utilising mixed methods, were conducted using PL athletes & coaches of all levels in an attempt to better understand the METD for 1RM strength. The studies of this multi-experiment paper are: an interview study with elite PL athletes and highly experienced PL coaches (
    Language English
    Publishing date 2021-08-30
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2021.713655
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  9. Article ; Online: Surgical Treatment of Facial Infantile Hemangiomas: An Analysis Based on Tumor Characteristics and Outcomes.

    Pavlidis, Leonidas / Spyropoulou, Georgia Alexandra / Michalopoulos, Nickos / Demiri, Efterpi

    Plastic and reconstructive surgery

    2016  Volume 138, Issue 5, Page(s) 947e–948e

    MeSH term(s) Face ; Hemangioma ; Hemangioma, Capillary ; Humans ; Infant ; Skin Neoplasms
    Language English
    Publishing date 2016-06-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000002690
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  10. Article: Confronting gastrocutaneous fistulas.

    Papavramidis, Theodossis S / Mantzoukis, Konstantinos / Michalopoulos, Nick

    Annals of gastroenterology

    2014  Volume 24, Issue 1, Page(s) 16–19

    Abstract: A gastrocutaneous fistula (GCF) represents a fistula connecting the stomach with the skin. The aim of the present review is to clarify the entity of a GCF and to discuss the various treating strategies employed. In order to elucidate GCFs as an entity ... ...

    Abstract A gastrocutaneous fistula (GCF) represents a fistula connecting the stomach with the skin. The aim of the present review is to clarify the entity of a GCF and to discuss the various treating strategies employed. In order to elucidate GCFs as an entity etiology was pointed out and relative pathogenetic mechanisms were explored. Moreover, diagnostic modalities are discussed with a special focus on GCFs following bariatric operations. Finally, the treating strategies currently employed when confronting GCFs are presented, as well as their effectiveness.
    Language English
    Publishing date 2014-04-08
    Publishing country Greece
    Document type Review
    ZDB-ID 2032850-3
    ISSN 1108-7471
    ISSN 1108-7471
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