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  1. Article ; Online: Changing the paradigm in health and care services: modern value chains using open innovation for the creation of new digital health solutions.

    Carrilho, Joana / Videira, Diogo / Campos, Cláudia / Midão, Luis / Costa, Elísio

    Frontiers in digital health

    2023  Volume 5, Page(s) 1216357

    Abstract: Digital Health is a subject of extensive discourse when considering its current and future significance. This significance arises from a convergence of various factors, including the escalating capabilities and cost-effectiveness of computing and ... ...

    Abstract Digital Health is a subject of extensive discourse when considering its current and future significance. This significance arises from a convergence of various factors, including the escalating capabilities and cost-effectiveness of computing and communication technology, coupled with the mounting demands and challenges faced by healthcare systems. The integration of health and technology, when studied collectively with the purpose of addressing tangible real-world issues, holds the potential to generate substantial outcomes that greatly influence the provision of clinical and social care, thereby enhancing the overall well-being of both individuals and populations. In this sense, in this paper we propose a collaborative approach, using Open Innovation, where the most relevant stakeholders-health and care professionals, citizens and companies-work together to develop and validate innovative digital solutions for health and care. We have called this approach of value co-creation the
    Language English
    Publishing date 2023-06-26
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-253X
    ISSN (online) 2673-253X
    DOI 10.3389/fdgth.2023.1216357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Palliative Care in the Ageing European Population: A Cross-Country Comparison.

    Cerullo, Giovanni / Figueiredo, Teodora / Coelho, Constantino / Campos, Cláudia Silva / Videira-Silva, António / Carrilho, Joana / Midão, Luís / Costa, Elísio

    International journal of environmental research and public health

    2024  Volume 21, Issue 1

    Abstract: With Europe's ageing population and rising demand for palliative care, it is crucial to examine the use of palliative care among older adults during their last years of life and understand the factors influencing their access and end-of-life ... ...

    Abstract With Europe's ageing population and rising demand for palliative care, it is crucial to examine the use of palliative care among older adults during their last years of life and understand the factors influencing their access and end-of-life circumstances. This study employed a cohort of SHARE participants aged 65 years or older who had passed away between Wave 6 (2015) and Wave 7 (2017). Information on death circumstances, palliative care utilization, and associated variables were analysed. The study revealed that nearly 13.0% of individuals across these countries died under palliative care, with Slovenia having the lowest rate (0.3%) and France the highest (30.4%). Palliative care utilization in the last 30 days before death was observed in over 24.0% of participants, with the Czech Republic having the lowest rate (5.0%) and Greece the highest (48.8%). A higher risk of using or dying in palliative care was significantly associated with cognitive impairment (low verbal fluency), physical inactivity, and good to excellent self-perceived health. This work highlights the urgent need for enhanced global access to palliative care and advocates for the cross-country comparison of effective practices within Europe, tailored to the unique healthcare needs of older adults.
    MeSH term(s) Humans ; Aged ; Palliative Care/psychology ; Aging/psychology ; Europe/epidemiology ; Czech Republic/epidemiology ; Health Facilities
    Language English
    Publishing date 2024-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph21010113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pre-Frailty and Frailty in Dialysis and Pre-Dialysis Patients: A Systematic Review of Clinical and Biochemical Markers.

    Pereira, Ana / Midão, Luís / Almada, Marta / Costa, Elísio

    International journal of environmental research and public health

    2021  Volume 18, Issue 18

    Abstract: Patients under dialysis are known to be more vulnerable to frailty, a dynamic geriatric syndrome defined as a state of vulnerability to stressors, due to numerous metabolic changes. With rise of life expectancy globally, it is important to understand the ...

    Abstract Patients under dialysis are known to be more vulnerable to frailty, a dynamic geriatric syndrome defined as a state of vulnerability to stressors, due to numerous metabolic changes. With rise of life expectancy globally, it is important to understand the complexity of the pathophysiology of frailty and identify possible markers that can help with the prognosis and diagnosis of frailty. The aim of this systematic review is to give an overview of the knowledge regarding clinical and biochemical markers associated with pre-frailty and frailty in dialysis and pre-dialysis patients. In November 2020, PubMed, Embase and Web of Science were searched. Studies regarding biomarkers associated with (pre-)frailty in (pre-)dialysis patients were included. This systematic review identified clinical and biochemical markers in pre-frail and frail patients under dialysis or pre-dialysis published in the literature. This study shows that more investigation is necessary to identify markers that can differentiate these processes to be used as a diagnostic and prognostic tool in routine care and management of geriatric needs. Interventions that can improve health outcomes in pre-frail and frail older adults under dialysis or pre-dialysis are essential to improve not only the individual's quality of life but also to reduce the burden to the health systems.
    MeSH term(s) Aged ; Biomarkers ; Dialysis ; Frail Elderly ; Frailty/diagnosis ; Humans ; Quality of Life
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-09-11
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph18189579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pharmacological Adherence Behavior Changes during COVID-19 Outbreak in a Portugal Patient Cohort.

    Midão, Luís / Almada, Marta / Carrilho, Joana / Sampaio, Rute / Costa, Elísio

    International journal of environmental research and public health

    2022  Volume 19, Issue 3

    Abstract: Concerns, behaviours, and beliefs influence how people deal with COVID-19. Understanding the factors influencing adherence behaviour is of utmost importance to develop tailored interventions to increase adherence within this context. Hence, we aimed to ... ...

    Abstract Concerns, behaviours, and beliefs influence how people deal with COVID-19. Understanding the factors influencing adherence behaviour is of utmost importance to develop tailored interventions to increase adherence within this context. Hence, we aimed to understand how COVID-19 affected adherence behaviour in Portugal. A cross-sectional online survey was conducted between 1 March and 3 April 2021. Descriptive statistics were performed, as well as univariable and multivariable regression models. Of the 1202 participants, 476 who were taking at least one medication prescribed by the doctor were selected. Of these, 78.2% were female, and the mean age was 40.3 ± 17.9 years old. About 74.2% were classified as being highly adherent. During the pandemic, 8.2% of participants reported that their adherence improved, while 5.9% had worsened adherence results. Compared with being single, widowers were 3 times more prone to be less adherent (OR:3.390 [1.106-10.390],
    MeSH term(s) Adult ; COVID-19 ; Cross-Sectional Studies ; Female ; Humans ; Medication Adherence ; Middle Aged ; Pandemics ; Portugal/epidemiology ; SARS-CoV-2 ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2022-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19031135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cognitive performance in older adults across Europe based on the SHARE database.

    Barbosa, Rui / Midão, Luís / Almada, Marta / Costa, Elísio

    Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition

    2020  Volume 28, Issue 4, Page(s) 584–599

    Abstract: With ageing mental health issues, as age-related cognitive decline, increase. This study aims to evaluate the prevalence of cognitive impairment among older European adults and to evaluate its association with clinical and sociodemographic variables, ... ...

    Abstract With ageing mental health issues, as age-related cognitive decline, increase. This study aims to evaluate the prevalence of cognitive impairment among older European adults and to evaluate its association with clinical and sociodemographic variables, using SHARE. Numeracy, temporal orientation, verbal fluency, and memory were the measures used to evaluate cognitive performance. From 44 963 individuals included, mean age was 70.0±9.0 years old and 56.3% were female. Overall prevalence of impairment was of 13.0% (temporal orientation), 24.8% (numeracy), 27.6% (verbal fluency) and 50.5% (memory). Men showed higher impairment prevalence in temporal orientation and memory and lower in numeracy and verbal fluency. Age, fewer years of education, difficulties performing iADLs, physical inactivity, and poor self-perceived health were independently associated with impairment in all cognitive abilities. These results showed the burden of cognitive impairment across Europe. Factors identified as associated should be taken in consideration to develop effective interventions to prevent cognitive decline.
    MeSH term(s) Aged ; Aged, 80 and over ; Aging ; Cognitive Dysfunction/epidemiology ; Databases, Factual ; Europe/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Prevalence
    Language English
    Publishing date 2020-08-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1482447-4
    ISSN 1744-4128 ; 1382-5585
    ISSN (online) 1744-4128
    ISSN 1382-5585
    DOI 10.1080/13825585.2020.1799927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Instrumental Activities of Daily Living (iADL) Limitations in Europe: An Assessment of SHARE Data.

    Portela, Diana / Almada, Marta / Midão, Luís / Costa, Elísio

    International journal of environmental research and public health

    2020  Volume 17, Issue 20

    Abstract: This study aims to evaluate the instrumental activities of daily living (iADLs) limitations in Europe and its association with socio-demographic characteristics, economic parameters and physical and mental health status. We used data from the wave 6 of ... ...

    Abstract This study aims to evaluate the instrumental activities of daily living (iADLs) limitations in Europe and its association with socio-demographic characteristics, economic parameters and physical and mental health status. We used data from the wave 6 of SHARE database. Individuals were classified as having either none or one or more limitations on iADLs. Participants aged 65 or more years who answered all questions for the variables included in this work were selected. A total of 54.8% of participants were female and had a mean age of 74.37 (SD = 7.08) years. A global prevalence of 1 or more iADLs in Europe was shown to be 23.8% and more prevalent in women than in men (27.1% vs. 17.6%) and in people aged 85 years or more (51.5%). Older age, female gender, lower education, physical inactivity, frailty, having two or more chronic diseases, presence of depression, polypharmacy, poor self-perception of health and lower network satisfaction were found to be factors associated with the presence of 1 or more iADLs limitation. This study highlights the burden of iADLs limitations at the European level. These are based on a multidimensional biopsychosocial model and are associated with both health conditions and environmental factors. This intersection between the physical and social world underscores its potential as a health indicator and can, to some extent, explain some of the pronounced differences seen among European countries. Different inter-tasks can also stress different dimensions of health indicators in distinct and specific groups of individuals. Minimizing the impact of iADL limitations can improve the quality and sustainability of public health systems.
    MeSH term(s) Activities of Daily Living ; Aged ; Aged, 80 and over ; Aging ; Cross-Sectional Studies ; Europe ; Female ; Frailty ; Humans ; Male ; Polypharmacy ; Risk Factors ; Socioeconomic Factors
    Language English
    Publishing date 2020-10-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17207387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The interplay between climate change and ageing: A systematic review of health indicators.

    Figueiredo, Teodora / Midão, Luís / Rocha, Pedro / Cruz, Sara / Lameira, Gisela / Conceição, Paulo / Ramos, Rui J G / Batista, Luísa / Corvacho, Helena / Almada, Marta / Martins, Ana / Rocha, Cecília / Ribeiro, Anabela / Alves, Fernando / Costa, Elísio

    PloS one

    2024  Volume 19, Issue 4, Page(s) e0297116

    Abstract: Climate change and rapid population ageing pose challenges for communities and public policies. This systematic review aims to gather data from studies that present health indicators establishing the connection between climate change and the physical and ...

    Abstract Climate change and rapid population ageing pose challenges for communities and public policies. This systematic review aims to gather data from studies that present health indicators establishing the connection between climate change and the physical and mental health of the older population (≥ 65 years), who experience a heightened vulnerability to the impacts of climate change when compared to other age cohorts. This review was conducted according to the PICO strategy and following Cochrane and PRISMA guidelines. Three databases (PubMed, Scopus and Greenfile) were searched for articles from 2015 to 2022. After applying inclusion and exclusion criteria,nineteen studies were included. The findings indicated that various climate change phenomena are associated with an elevated risk of mortality and morbidity outcomes in older adults. These included cardiovascular, respiratory, renal, and mental diseases, along with physical injuries. Notably, the impact of climate change was influenced by gender, socioeconomic status, education level, and age-vulnerability factors. Climate change directly affected the health of older adults through ambient temperature variability, extreme and abnormal temperatures, strong winds, sea temperature variability, extreme El Niño-southern Oscillation (ENSO) conditions and droughts, and indirectly by air pollution resulting from wildfires. This review presents further evidence confirming that climate change significantly impacts the health and well-being of older adults. It highlights the urgency for implementing effective strategies to facilitate adaptation and mitigation, enhancing the overall quality of life for all individuals.
    MeSH term(s) Humans ; Climate Change ; Aging/physiology ; Aged ; Aged, 80 and over ; Male ; Female ; Health Status Indicators
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Frailty Status and Polypharmacy Predict All-Cause Mortality in Community Dwelling Older Adults in Europe.

    Midão, Luís / Brochado, Pedro / Almada, Marta / Duarte, Mafalda / Paúl, Constança / Costa, Elísio

    International journal of environmental research and public health

    2021  Volume 18, Issue 7

    Abstract: European population ageing is associated with frailty, a complex geriatric syndrome, and polypharmacy, both resulting in adverse health outcomes. In this study we aimed to evaluate the impact of frailty and polypharmacy, on mortality rates, within 30 ... ...

    Abstract European population ageing is associated with frailty, a complex geriatric syndrome, and polypharmacy, both resulting in adverse health outcomes. In this study we aimed to evaluate the impact of frailty and polypharmacy, on mortality rates, within 30 months, using a cohort of SHARE participants aged 65 years old or more. Frailty was assessed using a version of Fried's phenotype criteria operationalized to SHARE while polypharmacy was defined as taking five or more drugs per day. We found a prevalence of 40.4% non-frail, 47.3% pre-frail and 12.3% frail participants. Moreover, a prevalence of polypharmacy of 31.3% was observed, being 3 three times more prevalent in frail individuals and two times in pre-frail individuals, when compared with non-frail. Individuals with both conditions had shown higher mortality rates. Comparing with non-polymedicated non-frail individuals all the other conditions are more prone to die within 30 months. Polymedicated older and male participants exhibited also higher mortality rates. This work shows polypharmacy and frailty to be associated with a higher risk of all-cause of mortality and highlights the need to decrease 'unnecessary' polypharmacy to reduce drug-related issues and also the need to assess frailty early to prevent avoidable adverse outcomes.
    MeSH term(s) Aged ; Europe/epidemiology ; Frail Elderly ; Frailty/epidemiology ; Geriatric Assessment ; Humans ; Independent Living ; Male ; Polypharmacy
    Language English
    Publishing date 2021-03-30
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph18073580
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Managing Non-Cancer Chronic Pain in Frail Older Adults: A Pilot Study Based on a Multidisciplinary Approach.

    Figueiredo, Teodora / Midão, Luís / Sampaio, Rute / Carrilho, Joana / Coelho, Constantino / Cerullo, Giovanni / Di Paola, Antonella / Carfì, Angelo / Onder, Graziano / Costa, Elísio

    International journal of environmental research and public health

    2023  Volume 20, Issue 24

    Abstract: Considering the multidimensionality of chronic pain, it is crucial to develop comprehensive strategies for its effective management. However, establishing well-defined, evidence-based guidelines for such approaches remains challenging. To overcome this, ... ...

    Abstract Considering the multidimensionality of chronic pain, it is crucial to develop comprehensive strategies for its effective management. However, establishing well-defined, evidence-based guidelines for such approaches remains challenging. To overcome this, we present the finding from a 4-month intervention to enhance the management of non-cancer chronic pain in older adults with pre-frailty and frailty. The intervention's core elements comprised a multidisciplinary individualized plan, a case manager, and patient education. This pilot study involved 22 participants (≥65 years). It assessed changes in pain frequency and intensity (pain scale), frailty (Fried frailty phenotype criteria), and medication adherence (Brief Adherence Rating Scale) before and after the 4-month intervention. The results were encouraging: pain frequency and intensity and frailty score tended to decrease, and medication adherence showed significant improvement. This preliminary small-scale pilot study provides a foundation for further research and for exploring the potential scalability of this multidisciplinary patient-centred intervention.
    MeSH term(s) Humans ; Aged ; Frail Elderly ; Chronic Pain/drug therapy ; Frailty ; Pilot Projects ; Geriatric Assessment/methods
    Language English
    Publishing date 2023-12-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20247150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Polypharmacy prevalence among older adults based on the survey of health, ageing and retirement in Europe.

    Midão, Luís / Giardini, Anna / Menditto, Enrica / Kardas, Przemyslaw / Costa, Elísio

    Archives of gerontology and geriatrics

    2018  Volume 78, Page(s) 213–220

    Abstract: Polypharmacy, a common condition among the elderly, is associated with adverse outcomes, including increased healthcare costs, due to higher mortality, falls and hospitalizations rates, adverse drug reactions, drug-drug reactions and medication ... ...

    Abstract Polypharmacy, a common condition among the elderly, is associated with adverse outcomes, including increased healthcare costs, due to higher mortality, falls and hospitalizations rates, adverse drug reactions, drug-drug reactions and medication nonadherence. This study aims to evaluate the prevalence and factors related to polypharmacy in older adults across 17 European countries, plus Israel. In this cross-sectional analysis, we used data from participants aged 65 or more years from Wave 6 of the Survey of Health, Ageing, and Retirement in Europe (SHARE) database. Polypharmacy was defined as the concurrent use of five or more medications. Age, gender, education, physical inactivity, number of limitations with activities of daily living, network satisfaction, quality of life, depression, number of chronic diseases and difficulty taking medication variables were found to be associated with polypharmacy. Our results showed a prevalence of polypharmacy ranging from 26.3 to 39.9%. Switzerland, Croatia and Slovenia were the countries with the lowest prevalence, whereas Portugal, Israel and the Czech Republic were the countries where the prevalence of polypharmacy was the highest. Age, gender, number of limitations with activities of daily living, number of chronic diseases, quality of life, depression, physical inactivity, network satisfaction, difficulty in taking medications, years of education and shortage of money were significant variables associated with polypharmacy. Polypharmacy is a highly prevalent condition in the elderly population. Identification of variables associated with polypharmacy, such as those identified in this study, is important to identify and monitor elderly groups, which are most vulnerable to polypharmacy.
    MeSH term(s) Activities of Daily Living ; Aged ; Aged, 80 and over ; Aging ; Cross-Sectional Studies ; Depression/epidemiology ; Europe/epidemiology ; Female ; Health Surveys ; Humans ; Male ; Polypharmacy ; Prevalence ; Quality of Life ; Retirement
    Language English
    Publishing date 2018-06-30
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603162-6
    ISSN 1872-6976 ; 0167-4943
    ISSN (online) 1872-6976
    ISSN 0167-4943
    DOI 10.1016/j.archger.2018.06.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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