LIVIVO - Search results -

Search results

Result 1 - 10 of total 35

Search options

Article ; Online: Doce river mining tailings can be an influencing factor in loggerhead turtles reproductive success in Brazil.

Miguel, Camila / Vianna, Monica Ryff Moreira / de Deus Santos, Marcelo Renan

2023 Volume 196, Page(s) 115601

Abstract: In November 2015, a tailings dam ruptured and affected the second largest nesting site of loggerhead sea turtles in Brazil. This study aimed to evaluate the reproductive success, and trace elements in female's plasma, freshly laid eggs, unhatched eggs, ... ...

Abstract	In November 2015, a tailings dam ruptured and affected the second largest nesting site of loggerhead sea turtles in Brazil. This study aimed to evaluate the reproductive success, and trace elements in female's plasma, freshly laid eggs, unhatched eggs, and dead hatchlings of loggerhead turtles that nest in the coastal area exposed to the mining waste (Povoação, Espírito Santo state) and compare them with animals from an area that was not affected by the tailings (Praia do Forte, Bahia state). Plasma concentrations of As, Cd, Cr, Fe, and Zn were significantly higher in samples from Povoação in comparison to turtles from Praia do Forte. In Povoação, unhatched eggs and dead hatchlings had higher As, Cu, Hg, Mn, and Zn concentrations than freshly laid eggs, and trace elements correlated with the hatching and emergence success. Our findings suggest that the higher concentrations of some metals may influence the incubation period and reproductive success of loggerheads in the affected area.
MeSH term(s)	Animals ; Female ; Trace Elements ; Turtles ; Brazil ; Rivers ; Metals
Chemical Substances	Trace Elements ; Metals
Language	English
Publishing date	2023-09-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2001296-2
ISSN	1879-3363 ; 0025-326X
ISSN (online)	1879-3363
ISSN	0025-326X
DOI	10.1016/j.marpolbul.2023.115601
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Potential Associations between Vascular Biology and Hodgkin's Lymphoma: An Overview.

Rodrigues, Wellington Francisco / Miguel, Camila Botelho / Abreu, Melissa Carvalho Martins de / Neto, Jamil Miguel / Oliveira, Carlo José Freire

Cancers

2023 Volume 15, Issue 21

Abstract: Hodgkin's lymphoma (HL) is a lymphatic neoplasm typically found in the cervical lymph nodes. The disease is multifactorial, and in recent years, the relationships between various vascular molecules have been explored in the field of vascular biology. The ...

Abstract	Hodgkin's lymphoma (HL) is a lymphatic neoplasm typically found in the cervical lymph nodes. The disease is multifactorial, and in recent years, the relationships between various vascular molecules have been explored in the field of vascular biology. The connection between vascular biology and HL is intricate and the roles of several pathways remain unclear. This review summarizes the cellular and molecular relationships between vascular biology and HL. Proteins associated with various functions in vascular biology, including cytokines (TNF-α, IL-1, IL-13, and IL-21), chemokines (CXCL10, CXCL12, and CCL21), adhesion molecules (ELAM-1/VCAM-1), and growth factors (BDNF/NT-3, platelet-derived growth factor receptor-α), have been linked to tumor activity. Notable tumor activities include the induction of paracrine activation of NF-kB-dependent pathways, upregulation of adhesion molecule regulation, genome amplification, and effective loss of antigen presentation mediated by MHC-II. Preclinical study models, primarily those using cell culture, have been optimized for HL. Animal models, particularly mice, are also used as alternatives to complex biological systems, with studies primarily focusing on the physiopathogenic evaluation of the disease. These biomolecules warrant further study because they may shed light on obscure pathways and serve as targets for prevention and/or treatment interventions.
Language	English
Publishing date	2023-11-06
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15215299
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Potential adverse effects of heavy metals on clinical health parameters of Caretta caretta from a nesting area affected by mining tailings in Brazil

Miguel, Camila / Santos, Marcelo Renan de Deus / Bianchini, Adalto / Vianna, Monica Ryff Moreira

Journal of trace elements and minerals. 2022 Dec., v. 2

2022

Abstract: In 2015, Brazil had its most notorious ecological disaster due to an iron mine dam collapse. It was considered the world's largest environmental disaster associated with mining industry. The tailings composed mostly of iron ore and silica, but with high ... ...

Abstract	In 2015, Brazil had its most notorious ecological disaster due to an iron mine dam collapse. It was considered the world's largest environmental disaster associated with mining industry. The tailings composed mostly of iron ore and silica, but with high levels of heavy metals reached the Atlantic Ocean, through the Doce River, sixteen days after the rupture. The region where the mud ran into the ocean is an important nesting area for loggerhead turtles (Caretta caretta) in Brazil (Povoação, Espírito Santo state). The aim of this study is to evaluate the heavy metal effects on the health parameters of loggerhead turtles that nest in the exposed area (Povoação, Doce river estuary) and compare them with turtles from another coastal area that was not affected by the tailings (Praia do Forte, Bahia state). Animals’ health status was determined by a physical examination during which blood samples used to perform biochemical and hematological analysis were also obtained. Heavy metal concentrations were evaluated in the blood and carapace scutes. Sea turtles from Povoação had a worse body condition with higher ectoparasitic and epibiont loads compared to Praia do Forte animals. They also showed eye lesions and more frequent fibropapillomatosis suggestive tumors. Several correlations between the contaminants and hematological and plasma biochemical analytes were found in loggerhead sea turtles from Povoação. Blood metal concentrations were distinct between nesting areas, with higher As, Cd, Cr, Fe, Pb, and Zn levels in animals from the affected area. In the carapace scute, the heavy metal levels were similar between sites. The occurrence of eye lesions, suggestive fibropapillomatosis tumors, worse body condition, higher ectoparasite count, greater epibiont loads, large number of correlations between health parameters and heavy metal levels, and higher levels of some metals in the blood of PV turtles indicates that the tailings could have a negative impact on the health and reproduction of these turtles. The long-term monitoring of the exposed area is important to quantify the direct and indirect impacts of the tailings on the health of these animals. Additionally, the data reported here are important for temporal and spatial comparative studies in the future.
Keywords	Caretta caretta ; body condition ; chemical species ; clinical examination ; coasts ; ectoparasites ; epibionts ; estuaries ; eyes ; health status ; heavy metals ; hematologic tests ; nests ; rivers ; silica ; Atlantic Ocean ; Brazil
Language	English
Dates of publication	2022-12
Publishing place	Elsevier B.V.
Document type	Article
ISSN	2773-0506
DOI	10.1016/j.jtemin.2022.100015
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Proximity matrix indicates heterogeneity in the ability to face child malnutrition and pandemics in Brazil: An ecological study.

Miguel, Camila Botelho / da Silva, Arianny Lima / Trindade-da-Silva, Carlos Antônio / de Abreu, Melissa Carvalho Martins / Oliveira, Carlo José Freire / Rodrigues, Wellington Francisco

Frontiers in public health

2022 Volume 10, Page(s) 1019300

Abstract: Background: Among the social inequalities that continue to still surpasses the basic rights of several citizens, political and environmental organizations decisively "drag" the "ghost" of hunger between different countries of the world, including Brazil. ...

Abstract	Background: Among the social inequalities that continue to still surpasses the basic rights of several citizens, political and environmental organizations decisively "drag" the "ghost" of hunger between different countries of the world, including Brazil. The COVID-19 pandemic has increased the difficulties encountered in fighting poverty, which has led Brazil to a worrying situation regarding its fragility in the fight against new pandemics. Objectives: The present study aims to estimate, compare, and report the prevalence of mortality due to child malnutrition among the macro-regions of Brazil and verify possible associations with the outcome of death by COVID-19. This would identify the most fragile macro-regions in the country with the greatest need for care and investments. Methods: The prevalence of mortality was determined using data from the federal government database (DataSus). Child malnutrition was evaluated for the period from 1996 to 2017 and COVID-19 was evaluated from February to December 2020. The (dis)similarity between deaths from malnutrition and COVID-19 was evaluated by proximity matrix. Results: The North and Northeast regions have above average number of deaths than expected for Brazil ( Conclusions: There are discrepancies in frequencies between macro-regions. Prospective data indicate serious problems for the North and Northeast regions for the coming years. Therefore, strategies to contain the outcome of health hazards must be intensified in the macro-regions North and Northeast of the country.
MeSH term(s)	Child ; Humans ; Brazil/epidemiology ; Pandemics ; Child Nutrition Disorders/epidemiology ; COVID-19/epidemiology ; Malnutrition/epidemiology
Language	English
Publishing date	2022-11-10
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.1019300
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Health condition of Chelonia mydas from a foraging area affected by the tailings of a collapsed dam in southeast Brazil.

Miguel, Camila / Costa, Patrícia Gomes / Bianchini, Adalto / Luzardo, Octavio Luis Pérez / Vianna, Monica Ryff Moreira / Santos, Marcelo Renan de Deus

The Science of the total environment

2022 Volume 821, Page(s) 153353

Abstract: In 2015, the failure of the Fundão dam caused the release of 43 million ... ...

Abstract	In 2015, the failure of the Fundão dam caused the release of 43 million m
MeSH term(s)	Animals ; Brazil ; Ecosystem ; Environmental Monitoring ; Metals, Heavy/analysis ; Turtles/metabolism ; Water Pollutants, Chemical/analysis
Chemical Substances	Metals, Heavy ; Water Pollutants, Chemical
Language	English
Publishing date	2022-01-25
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.153353
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 949: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Health condition of Chelonia mydas from a foraging area affected by the tailings of a collapsed dam in southeast Brazil

Miguel, Camila / Costa, Patrícia Gomes / Bianchini, Adalto / Luzardo, Octavio Luis Pérez / Vianna, Monica Ryff Moreira / Santos, Marcelo Renan de Deus

Science of the total environment. 2022 May 15, v. 821

2022

Abstract: In 2015, the failure of the Fundão dam caused the release of 43 million m³ of tailings into the Doce River Basin, in southeast Brazil. It was considered the largest environmental disaster of the world mining industry. The tailings, composed mostly of ... ...

Abstract	In 2015, the failure of the Fundão dam caused the release of 43 million m³ of tailings into the Doce River Basin, in southeast Brazil. It was considered the largest environmental disaster of the world mining industry. The tailings, composed mostly of heavy metals, caused massive destruction of the Doce River ecosystem endangering the organisms that live in the coastal zone where the mud reached the ocean. Among the exposed species are the sea turtles that use the region for food. The aim of this study was to evaluate the effect of contaminants on the health status of juvenile green sea turtles that feed in a coastal area exposed to ore mud (Santa Cruz) and to compare them with animals from an area not directly affected (Coroa Vermelha). A physical examination was performed to determine the health status. Blood samples were analyzed for hematological and biochemical parameters, and metal concentrations (As, Cd, Cr, Cu, Fe, Hg, Mn, Pb, and Zn). Santa Cruz sea turtles had more ectoparasites and a higher incidence of fibropapillomatosis. Statistically significant differences between sites were found for levels of calcium, phosphorus, glucose, protein, albumin, globulin, cholesterol, triglycerides, urea, CPK, ALT, and AST. The count of leukocytes, thrombocytes, and heterophils, as well as the concentrations of As and Cu were higher in Santa Cruz turtles. Together the results show a worse nutritional status and a greater degree of liver and kidney damage in animals affected by the tailings. The health status may indicate a physiological deficit that can affect their immune system and behavior, which is supported by the higher fibropapillomatosis tumor score and ectoparasite load in these animals. These results support the need for long-term monitoring of the exposed area to quantify the direct and indirect influence of the heavy metals levels on sea turtles and how this reflects the environmental health.
Keywords	Chelonia mydas ; albumins ; blood platelets ; calcium ; cholesterol ; clinical examination ; coasts ; ecosystems ; ectoparasites ; environment ; environmental health ; globulins ; glucose ; health status ; heterophils ; juveniles ; kidneys ; liver ; neoplasms ; nutritional status ; phosphorus ; rivers ; urea ; watersheds ; Brazil
Language	English
Dates of publication	2022-0515
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.153353
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 74/341: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Soluble epoxide hydrolase inhibitors for smoking-associated inflammatory lung diseases and chronic obstructive pulmonary disease: a meta-analytical systematic review of preclinical and clinical studies.

Felipe, Alberto G Borges / Miguel, Camila B / Bernardes, Ana P Lazarin / Perissinotto, Rodrigo / Trindade-da-Silva, Carlos A / Martins-de-Abreu, Melissa C / Miguel-Neto, Jamil / Rodrigues, Wellington F / Oliveira, Carlo J Freire

American journal of translational research

2023 Volume 15, Issue 11, Page(s) 6649–6659

Abstract: An evaluation of the inflammatory enzymatic interactions related to pulmonary function can help identify biomarkers for interventions or prophylactic measures to improve patient prognosis. This study aimed to determine the effect of epoxide hydrolase ... ...

Abstract	An evaluation of the inflammatory enzymatic interactions related to pulmonary function can help identify biomarkers for interventions or prophylactic measures to improve patient prognosis. This study aimed to determine the effect of epoxide hydrolase inhibition by GSK2256294 in different pulmonary inflammation models. A secondary search was performed using Medline/PubMed, Web of Science, SciELO, Cochrane Library, Embase, Academic Google, and gray literature by two independent reviewers, who analyzed the methodological quality and consistency of the data. Different variables were compared using a meta-analysis. A total of 86 studies were found, 4 of which were selected from the gray literature. Based on the eligibility criteria, two clinical and one preclinical studies were evaluated. GSK2256294 inhibited the soluble epoxide hydrolase enzyme in both clinical and preclinical models, exhibiting greater effectiveness in clinical studies and contributing to the anti-inflammatory activity mediated by the eicosatrienoic pathway by reducing the levels of dihydroxyeicosatrienoic acids and leukotoxin-diol. Overall, GSK2256294 was identified as a promising drug for controlling the deleterious manifestations of lung inflammation. Further clinical and preclinical studies are required to ensure consistency among the evidence and identify other biological activities mediated by GSK2256294.
Language	English
Publishing date	2023-11-15
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Coevolutionary Implications of Obligate Commensalism in Sea Turtles: the Case of the Genus

Iwasa-Arai, Tammy / Andrade, Sónia C S / Miguel, Camila / Siqueira, Silvana G L B / Werneck, Max Rondon / Leite, Fosca P P / Moraes, Lara / Santos, Marcelo Renan D / Medeiros, Luciana S / Lopes, Uylia H / Serejo, Cristiana

Zoological studies

2023 Volume 62, Page(s) e54

Abstract: Obligate commensalism in the marine environment and its evolutionary role are still poorly understood. Although sea turtles may serve as ideal substrates for epibionts, within amphipods, only the ... ...

Abstract	Obligate commensalism in the marine environment and its evolutionary role are still poorly understood. Although sea turtles may serve as ideal substrates for epibionts, within amphipods, only the genus
Language	English
Publishing date	2023-12-13
Publishing country	China (Republic : 1949- )
Document type	Journal Article
ZDB-ID	2105348-0
ISSN	1810-522X ; 1810-522X
ISSN (online)	1810-522X
ISSN	1810-522X
DOI	10.6620/ZS.2023.62-54
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Administration of artinm lectin reduces the severity of the acute phase infection with

Miguel, Camila Botelho / da Silva, Thiago Aparecido / Rodrigues, Wellington Francisco / Oliveira-Brito, Patrícia Kellen Martins / Roque-Barreira, Maria Cristina / Lazo-Chica, Javier Emílio

FASEB bioAdvances

2021 Volume 3, Issue 5, Page(s) 295–304

Abstract: The acute phase of ... ...

Abstract	The acute phase of experimental
Language	English
Publishing date	2021-01-25
Publishing country	United States
Document type	Journal Article
ISSN	2573-9832
ISSN (online)	2573-9832
DOI	10.1096/fba.2020-00065
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Physiological effects of incidental capture and seasonality on juvenile green sea turtles (Chelonia mydas)

Miguel, Camila / Becker, José Henrique / de Freitas, Betânia Souza / Touguinha, Luciana Bavaresco Andrade / Salvador, Mirian / Oliveira, Guendalina Turcato

Journal of experimental marine biology and ecology. 2020 Dec., v. 533

2020

Abstract: Fishery is one of the main threats faced by sea turtles. However, literature relating to the physiological effects of incidental capture by fishing gears is scarce. The aim of this study is to establish blood reference values for a juvenile population of ...

Abstract	Fishery is one of the main threats faced by sea turtles. However, literature relating to the physiological effects of incidental capture by fishing gears is scarce. The aim of this study is to establish blood reference values for a juvenile population of Chelonia mydas, from Ubatuba- Brazil, and compare them with incidental captured animals by fisheries in the same area, considering seasonal variation. Animals were captured during summer and winter, from direct capture (diving) and incidental capture (pound net and gillnet). Blood samples were collected from 96 healthy green sea turtles and, were analyzed for determining levels of glucose, lactate, total protein, uric acid, albumin, total lipids, triglycerides, VLDL cholesterol, total cholesterol, corticosterone concentrations, total antioxidant capacity, and lipid peroxidation. Corticosterone concentrations were significantly lower in animals captured by diving than in those captured by pound net and gillnet and were thought tso more closely represent baseline levels. Thus, the values found in animals captured by diving were used to establish reference values for this population. Turtles captured in summer had a significant increase in blood levels of glucose, total protein, uric acid, albumin, TBARS, and TEAC; and a decrease in total lipids compared with turtles captured in winter. Although pound nets are considered a low impact fishery to the turtles due to the low mortality rates, seven out of twelve parameters differed significantly from baseline values established for the species. Entanglement in gillnets caused greater perturbations than pound net and all parameters analyzed were significantly different from the reference values. These data indicate that incidental capture causes substantial alterations in health parameters of sea turtles. The results obtained in this study would help in future rehabilitation programs of sea turtles that are captured by fisheries. Additionally, reference values can be used for future comparisons with populations of the same species and with unhealthy and stressed individuals.
Keywords	Chelonia mydas ; albumins ; antioxidant activity ; blood ; cholesterol ; corticosterone ; fisheries ; gillnets ; glucose ; juveniles ; lactic acid ; lipid peroxidation ; mortality ; protein content ; seasonal variation ; summer ; uric acid ; very low density lipoprotein ; winter ; Brazil
Language	English
Dates of publication	2020-12
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	410283-6
ISSN	0022-0981
ISSN	0022-0981
DOI	10.1016/j.jembe.2020.151460
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 74/703: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED