Article ; Online: Toxic epidermal necrolysis (TEN): Acute complications and long-term sequelae management in a multidisciplinary follow-up.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
2019 Volume 73, Issue 2, Page(s) 319–327
Abstract: Background: Toxic epidermal necrolysis (TEN) is a devastating exfoliative disorder with life-changing complications. This study aimed to identify acute complications and long-term sequelae of TEN and to highlight the importance of a multidisciplinary ... ...
| Abstract | Background: Toxic epidermal necrolysis (TEN) is a devastating exfoliative disorder with life-changing complications. This study aimed to identify acute complications and long-term sequelae of TEN and to highlight the importance of a multidisciplinary management follow-up. Methods: A 19-year (1998-2016) retrospective review of all patients with TEN admitted to Cruces University Hospital´s Burns Unit was performed. Demographic and admission data were collected. Survivors were contacted for a follow-up multidisciplinary assessment involving dermatological, ocular, ENT, urological, gynecological, and psychological examination. Results: Within the total cohort of patients analyzed (22), 6 survivors agreed to be interviewed. The patients presented with both physical and psychological sequelae, including dermatological (100%), oropharyngeal (50%), and ophthalmologic sequelae (50%), with corneal damage and severe dry eye as the most frequent. The only male patient underwent phimosis surgery due to mucosal adhesions. Psychometric scales captured symptoms of post-traumatic stress disorder (33.33%), and quality of life was affected in 66.67% of the patients by skin sequelae. Conclusion: Quality of life can be severely impaired by multiple long-term complications. It is important to emphasize the need for multidisciplinary awareness during their acute stay at Burns Unit. Furthermore, long-term follow-up might prevent or limit the progression of the chronic sequelae. |
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| MeSH term(s) | Acute Disease ; Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Patient Care Team ; Quality of Life ; Retrospective Studies ; Stevens-Johnson Syndrome/complications ; Stevens-Johnson Syndrome/therapy ; Time Factors |
| Language | English |
| Publishing date | 2019-08-08 |
| Publishing country | Netherlands |
| Document type | Journal Article |
| ZDB-ID | 2217750-4 |
| ISSN | 1878-0539 ; 1748-6815 ; 0007-1226 |
| ISSN (online) | 1878-0539 |
| ISSN | 1748-6815 ; 0007-1226 |
| DOI | 10.1016/j.bjps.2019.07.015 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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