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  1. Article ; Online: Dermoscopic insight into skin microcirculation--Burn depth assessment.

    Mihara, Kyomi / Nomiyama, Tomoko / Masuda, Koji / Shindo, Hajime / Yasumi, Maki / Sawada, Takahiro / Nagasaki, Kotaro / Katoh, Norito

    Burns : journal of the International Society for Burn Injuries

    2015  Volume 41, Issue 8, Page(s) 1708–1716

    Abstract: To investigate the effectiveness of dermoscopic observation of skin microcirculation, the dermal capillary integrity of burn wounds was evaluated by dermoscopy according to a proposed algorithm that is designed to distinguish burn wounds between ... ...

    Abstract To investigate the effectiveness of dermoscopic observation of skin microcirculation, the dermal capillary integrity of burn wounds was evaluated by dermoscopy according to a proposed algorithm that is designed to distinguish burn wounds between superficial dermal burns: SDB, and deep dermal burns: DDB. As the gold standard for comparison, two widely accepted endpoints of primary healing within 21 days (SDB) or over 21 days after injury (DDB) were used. A number of dermatologists conducted diagnostic imaging by dermoscopy. Comparison among polarized noncontact dermoscopy (PNCD), polarized contact dermoscopy (PCD) and nonpolarized contact dermoscopy (NPD) was also conducted. Images from the three modalities were evaluated for color, pattern and qualitative differences among them. The results of dermoscopy measurements according to the proposed algorithm showed accuracy of 96.7%, sensitivity of 100.0% and specificity of 94.4%. Dermoscopy measurements were significantly more accurate than clinical assessment (p<0.05). The recognition of dots increased for NPD, vessels were most clearly observed under PCD and colours tended to be more distinctly recognized under polarized light. Dermoscopy is a useful and simple tool to evaluate not only epidermal and superficial dermal skin components but also the skin microcirculation.
    MeSH term(s) Adolescent ; Adult ; Aged ; Algorithms ; Burns/diagnosis ; Burns/pathology ; Dermoscopy/methods ; Female ; Humans ; Male ; Microcirculation ; Microscopy, Polarization ; Middle Aged ; Skin/blood supply ; Skin/pathology ; Trauma Severity Indices ; Young Adult
    Language English
    Publishing date 2015-12
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 197308-3
    ISSN 1879-1409 ; 0305-4179
    ISSN (online) 1879-1409
    ISSN 0305-4179
    DOI 10.1016/j.burns.2015.08.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Early depth assessment of local burns by dermoscopy: a new frontier of dermoscopic evaluation.

    Mihara, Kyomi / Shindo, Hajime / Mihara, Hiroya / Ohtani, Minako / Nagasaki, Kotaro / Katoh, Norito

    publication RETRACTED

    Archives of dermatology

    2012  , Page(s) E1

    Abstract: Unlabelled: This article has been retracted. See Notice of Retraction.: Objective: To investigate the effectiveness of early depth assessment of local burns, the depth of which is difficult to assess with the naked eye, by dermoscopy.: Design: The ...

    Abstract Unlabelled: This article has been retracted. See Notice of Retraction.
    Objective: To investigate the effectiveness of early depth assessment of local burns, the depth of which is difficult to assess with the naked eye, by dermoscopy.
    Design: The morphological findings of burn wounds were prospectively evaluated by dermoscopy and videomicroscopy. Prior to dermoscopic and videomicroscopic measurement, clinical assessment was performed. All patients received conservative treatment for 21 days after injury.
    Setting: A burns unit at a primary care hospital.
    Participants: Thirty-two patients with 41 intermediate-depth local burn wounds were included. Inclusion criteria were time to presentation greater than 24 hours after injury and total burn size greater than 1% and less than 10% of the total body surface area.
    Main outcome measures: Primary healing within 21 days (superficial partial thickness) and failure of primary healing within 21 days (deep partial thickness). The accuracy, sensitivity, and specificity of the assessment according to the algorithm proposed in this study were evaluated by dermoscopy, and the accuracy of the dermoscopic measurements was compared with videomicroscopic measurements and clinical assessments.
    Results: The results of dermoscopic measurements according to the proposed algorithm showed an accuracy of 93%, sensitivity of 86%, and specificity of 100%. The dermoscopic measurements were significantly more accurate compared with clinical assessment (P = .01).
    Conclusions: Dermoscopy is a noninvasive, portable, relatively inexpensive, and effective approach for assessment of the burn wound healing potential. It is more accurate if compared with clinical observation in burn depth assessment. It has a broader utility and is equally or more accurate compared with the more expensive videomicroscopy.
    Language English
    Publishing date 2012-05-03
    Publishing country United States
    Document type Journal Article ; Retracted Publication
    ZDB-ID 212139-6
    ISSN 1538-3652 ; 0003-987X
    ISSN (online) 1538-3652
    ISSN 0003-987X
    DOI 10.1001/archdermatol.2012.418
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Early depth assessment of local burns by videomicroscopy: a novel proposed classification.

    Mihara, Kyomi / Shindo, Hajime / Mihara, Hiroya / Ohtani, Minako / Nagasaki, Kotaro / Katoh, Norito

    Burns : journal of the International Society for Burn Injuries

    2012  Volume 38, Issue 3, Page(s) 371–377

    Abstract: Purpose: Videomicroscopy is very useful for burn depth assessment in an early phase; however, there is no practical classification that includes complicated anatomic, pathologic, and morphologic findings of burn wounds. The aim of this study was to ... ...

    Abstract Purpose: Videomicroscopy is very useful for burn depth assessment in an early phase; however, there is no practical classification that includes complicated anatomic, pathologic, and morphologic findings of burn wounds. The aim of this study was to propose a novel classification to assess burn depth in its early phase easily and reliably by videomicroscopy.
    Methods: Forty-four patients with 56 intermediate-depth burn wounds were included. Burn depth was divided into each grade according to our proposed classification, which is composed of five categories based on dermal capillary integrity patterns. The intrarater and interrater reliabilities of the assessment by the second and third authors were evaluated by Cohen's unweighted κ-value.
    Results: The results of the measurements according to the proposed classification showed an accuracy of 92.9%, sensitivity of 81.8%, and specificity of 100.0%. The intrarater reliability of the second and third authors showed substantial agreement (κ=0.719 and 0.729, respectively). The interrater reliability of the sum of each observer's variable also showed substantial agreement (κ=0.636).
    Conclusion: This pattern analysis system is easy to use even for inexperienced personnel, and is reliable with high accuracy and specificity. Intrarater and interrater statistics also support its reliability and reproducibility.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Burns/classification ; Burns/pathology ; Female ; Humans ; Male ; Microscopy, Video/standards ; Middle Aged ; Observer Variation ; Sensitivity and Specificity ; Young Adult
    Language English
    Publishing date 2012-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 197308-3
    ISSN 1879-1409 ; 0305-4179
    ISSN (online) 1879-1409
    ISSN 0305-4179
    DOI 10.1016/j.burns.2011.08.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Early depth assessment of local burns by videomicroscopy: 24 h after injury is a critical time point.

    Mihara, Kyomi / Shindo, Hajime / Ohtani, Minako / Nagasaki, Kotaro / Nakashima, Reiko / Katoh, Norito / Kishimoto, Saburo

    Burns : journal of the International Society for Burn Injuries

    2011  Volume 37, Issue 6, Page(s) 986–993

    Abstract: Purpose: Videomicroscopy has simple and prompt operability, and useful in the burn depth assessment in its early phase. A burn wound is, however, a dynamic environment in the first few days and the critical time to assess a burn wound by videomicroscopy ...

    Abstract Purpose: Videomicroscopy has simple and prompt operability, and useful in the burn depth assessment in its early phase. A burn wound is, however, a dynamic environment in the first few days and the critical time to assess a burn wound by videomicroscopy has not been investigated. The aim of this study is to investigate the critical time point to assess the burn depth by videomicroscopy.
    Methods: Forty one patients with 44 intermediate depth burns admitted within 7 days after injury were included. Accuracies were assessed by comparison with clinical outcome: healing within 21 days after injury or not with conservative treatment. We prospectively evaluated and compared the accuracy of the videomicroscopy measurements with the clinical assessments. All findings were serialized in order of time after injury and divided into three groups, and we compared the appreciation of burn depth by videomicroscopy findings among groups.
    Results: The videomicroscopy measurements is significantly accurate compared with clinical assessments (p=0.001). The accuracy of videomicroscopy measurements was significantly lower in the post-injury <24 h group compared with post-injury ≥24 h group (p=0.004).
    Conclusion: Videomicroscopy is effective tool in assessment of early burn depth and the critical time point to assess the burn depth by videomicroscopy is 24 h after injury.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Burns/pathology ; Female ; Humans ; Japan ; Male ; Microscopy, Video/instrumentation ; Microscopy, Video/methods ; Middle Aged ; Prospective Studies ; Sensitivity and Specificity ; Time Factors ; Young Adult
    Language English
    Publishing date 2011-09
    Publishing country Netherlands
    Document type Comparative Study ; Evaluation Studies ; Journal Article
    ZDB-ID 197308-3
    ISSN 1879-1409 ; 0305-4179
    ISSN (online) 1879-1409
    ISSN 0305-4179
    DOI 10.1016/j.burns.2011.03.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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