Article: Rituximab-associated interstitial lung disease in fibrillary glomerulonephritis.
2013 Volume 6, Issue 5, Page(s) 510–512
Abstract: Rituximab (RTX) is a chimeric monoclonal antibody against CD20+ B cells increasingly used to treat kidney disorders. RTX-induced pulmonary disease has been reported in patients treated for haematological disorders, and a few cases have been observed in ... ...
Abstract | Rituximab (RTX) is a chimeric monoclonal antibody against CD20+ B cells increasingly used to treat kidney disorders. RTX-induced pulmonary disease has been reported in patients treated for haematological disorders, and a few cases have been observed in patients with underlying rheumatological conditions. We report a case of non-infectious interstitial pneumonitis associated with RTX use in a 49-year-old patient with primary (fibrillary) glomerulonephritis. As typically observed, discontinuation of the drug and prompt initiation of glucocorticoids led to resolution of pulmonary manifestations. However, fatalities have been reported and nephrologists treating glomerulonephritis patients with RTX should be aware of the existence of this potentially lethal complication. |
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Language | English |
Publishing date | 2013-09-01 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 2655800-2 |
ISSN | 2048-8513 ; 2048-8505 |
ISSN (online) | 2048-8513 |
ISSN | 2048-8505 |
DOI | 10.1093/ckj/sft081 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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