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  1. Article: "It Makes you Want to Go Out and Change the World"

    AbiNader, Millan A

    Journal of family violence

    2023  , Page(s) 1–10

    Abstract: Purpose: Intimate partner violence (IPV) victim advocates are exposed daily to the traumas of their clients, including the potential exposure to an intimate partner homicide (IPH). While research has examined the effects of daily secondary exposure to ... ...

    Abstract Purpose: Intimate partner violence (IPV) victim advocates are exposed daily to the traumas of their clients, including the potential exposure to an intimate partner homicide (IPH). While research has examined the effects of daily secondary exposure to IPV on victim advocates, little is known about the specific effect of IPH. This study examined how the IPH of a client affected advocates' perception of and approach to their work.
    Methods: Nine advocates were recruited from the northeastern U.S. and interviewed about their experience of the IPH of a client. Advocate interviews were analyzed using The Listening Guide Analysis which systematically isolates and listens to the different, and often contradictory, voices that a participant uses.
    Results: Exposure to IPH changed participants' perception of their role, how they defined client, and how they interacted with future clients. At a macro-level, the IPH of a client motivated advocates to advance changes in agency protocol, multisector responses, and state policy based on what they had learned from the IPH. Opportunities to translate shifts in their worldview into tangible changes to protocol and policy were critical to advocate adjustment after the IPH.
    Conclusions: In order to support advocates after IPH, organizations should acknowledge the potentially transformative effect of IPH and create opportunities for meaning making to assist in advocate adjustment. It is imperative for advocacy organizations to support their employees to prevent advocate burnout and the loss of experienced staff, and to continue to provide effective services to vulnerable members of their communities after IPH.
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2016884-6
    ISSN 1573-2851 ; 0885-7482
    ISSN (online) 1573-2851
    ISSN 0885-7482
    DOI 10.1007/s10896-023-00544-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: In response to the editorial 'We're on mute! Exclusion of nurses' voices in national decision and responses to COVID-19: An international perspective'.

    McMillan, Alison

    Journal of advanced nursing

    2022  Volume 78, Issue 11, Page(s) e150

    MeSH term(s) COVID-19 ; Humans ; Internationality ; Nurses
    Language English
    Publishing date 2022-11-15
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 197634-5
    ISSN 1365-2648 ; 0309-2402
    ISSN (online) 1365-2648
    ISSN 0309-2402
    DOI 10.1111/jan.15441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1851: Show issues Location:
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  3. Article: Ankylostomiasis Duodenale.

    McMillan, A B

    Atlanta journal-record of medicine

    2022  Volume 5, Issue 1, Page(s) 13–15

    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The journey of bacterial genes.

    San Millan, Alvaro

    Nature ecology & evolution

    2022  Volume 6, Issue 5, Page(s) 498–499

    MeSH term(s) Genes, Bacterial
    Language English
    Publishing date 2022-03-26
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2397-334X
    ISSN (online) 2397-334X
    DOI 10.1038/s41559-022-01713-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Quantifying the performance enhancement facilitated by fractional-order implementation of classical control strategies for nanopositioning.

    Wang, Tiecheng / San-Millan, Andres / Aphale, Sumeet S

    ISA transactions

    2024  Volume 147, Page(s) 153–162

    Abstract: For most nanopositioning systems, maximizing positioning bandwidth to accurately track periodic and aperiodic reference signals is the primary performance goal. Closed-loop control schemes are employed to overcome the inherent performance limitations ... ...

    Abstract For most nanopositioning systems, maximizing positioning bandwidth to accurately track periodic and aperiodic reference signals is the primary performance goal. Closed-loop control schemes are employed to overcome the inherent performance limitations such as mechanical resonance, hysteresis and creep. Most reported control schemes are integer-order and combine both damping and tracking actions. In this work, fractional-order controllers from the positive position feedback family namely: the Fractional-Order Integral Resonant Control (FOIRC), the Fractional-Order Positive Position Feedback (FOPPF) controller, the Fractional-Order Positive Velocity and Position Feedback (FOPVPF) controller and the Fractional-Order Positive, Acceleration, Velocity and Position Feedback (FOPAVPF) controller are designed and analysed. Compared with their classical integer-order implementation, the fractional-order damping and tracking controllers furnish additional design (tuning) parameters, facilitating superior closed-loop bandwidth and tracking accuracy. Detailed simulated experiments are performed on recorded frequency-response data to validate the efficacy, stability and robustness of the proposed control schemes. The results show that the fractional-order versions deliver the best overall performance.
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2024.01.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Climate Change Act will now shape the nation's health: an assessment of the first policy recommendations to reach our zero carbon target.

    MacMillan, Alex

    The New Zealand medical journal

    2021  Volume 134, Issue 1530, Page(s) 8–11

    MeSH term(s) Carbon Footprint/standards ; Climate Change ; Health Policy ; Humans ; New Zealand
    Language English
    Publishing date 2021-02-19
    Publishing country New Zealand
    Document type Editorial
    ZDB-ID 390590-1
    ISSN 1175-8716 ; 0028-8446 ; 0110-7704
    ISSN (online) 1175-8716
    ISSN 0028-8446 ; 0110-7704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.396: Show issues Location:
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  7. Article ; Online: A new warhead in lymphoma therapy?

    McMillan, Andrew

    Blood

    2021  Volume 137, Issue 19, Page(s) 2568–2570

    MeSH term(s) Humans ; Lymphoma/drug therapy
    Language English
    Publishing date 2021-05-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2020009782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.140: Show issues Location:
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    Zs.MO 364: Show issues

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  8. Article ; Online: Conditioned pain modulation (CPM) paradigm type affects its sensitivity as a biomarker of fibromyalgia.

    Gil-Ugidos, A / Vázquez-Millán, A / Samartin-Veiga, N / Carrillo-de-la-Peña, M T

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7798

    Abstract: Fibromyalgia (FM) is a widespread chronic pain syndrome, possibly associated with the presence of central dysfunction in descending pain inhibition pathways. Conditioned Pain Modulation (CPM) has been proposed as a biomarker of FM. Nonetheless, the wide ... ...

    Abstract Fibromyalgia (FM) is a widespread chronic pain syndrome, possibly associated with the presence of central dysfunction in descending pain inhibition pathways. Conditioned Pain Modulation (CPM) has been proposed as a biomarker of FM. Nonetheless, the wide variety of methods used to measure CPM has hampered robust conclusions being reached. To clarify the validity of CPM as a biomarker of FM, we tested two CPM paradigms (parallel and sequential) in a sample of 23 female patients and 23 healthy women by applying test (mechanical) stimuli and conditioning (pressure cuff) stimuli. We evaluated whether CPM indices could correctly classify patients and controls, and we also determined the correlations between the indices and clinical variables such as symptomatology, disease impact, depression, quality of life, pain intensity, pain interference, fatigue and numbness. In addition, we compared the clinical status of CPM responders (efficient pain inhibitory mechanism) and non-responders. We observed that only parallel CPM testing correctly classified about 70% of patients with FM. In addition, more than 80% of healthy participants were found to be responders, while the rate was about 50% in the FM patients. The sequential CPM test was not as sensitive, with a decrease of up to 40% in the response rate for both groups. On the other hand, we did not observe any correlation between CPM measures and clinical symptoms. In summary, our findings demonstrate the influence of the CPM paradigm used and confirm that CPM may be a useful marker to complement FM diagnosis. However, the findings also cast doubts on the sensitivity of CPM as a marker of pain severity in FM.
    MeSH term(s) Humans ; Female ; Fibromyalgia ; Quality of Life ; Chronic Pain/diagnosis ; Chronic Pain/complications ; Pain Measurement/methods ; Biomarkers ; Pain Threshold/physiology
    Chemical Substances Biomarkers
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-58079-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A review of the long-term use of proton pump inhibitors and risk of celiac disease in the context of HLA-DQ2 and HLA-DQ8 genetic predisposition.

    McMillan, Alexandra / Perez, Christopher / Brooks, Amanda E

    Medicine

    2023  Volume 102, Issue 38, Page(s) e35351

    Abstract: Proton pump inhibitors (PPIs) are among the most prescribed and widely used medications; however, the long-term effects of these medications are only beginning to be investigated. Since the introduction of omeprazole in 1989, PPIs have become the first- ... ...

    Abstract Proton pump inhibitors (PPIs) are among the most prescribed and widely used medications; however, the long-term effects of these medications are only beginning to be investigated. Since the introduction of omeprazole in 1989, PPIs have become the first-choice treatment for esophagitis, peptic ulcer disease, Zoster-Ellison syndrome, dyspepsia, and the prevention of ulcers with non-steroidal anti-inflammatory drugs. Recent studies have specifically examined the rise in celiac disease (CD) in this context. This review explores how PPIs may impact the development of CD and highlights the need for additional research into the environmental and genetic factors that influence the development and progression of the disease. A literature search was performed using the keywords celiac disease, proton pump inhibitors, human leukocyte antigen (HLA)-DQ2, HLA-DQ8. The pathogenesis of CD is multifactorial, and human leukocyte antigens are one factor that may contribute to its development. Additionally, pharmaceuticals, such as PPIs, that cause gut dysbiosis have been linked to the inflammatory response present in CD. Recent studies have suggested that the rise in CD could be attributed to changes in the gut microbiome, highlighting the significant role that gut microbiota is proposed to play in CD pathogenesis. Although PPI therapy is helpful in reducing acid production in gastroesophageal disorders, additional information is needed to determine whether PPIs are still an appropriate treatment option with the possibility of developing CD in the future, particularly in the context of HLA-DQ2 and HLA-DQ8 predispositions. This review emphasizes the importance of personalized medicine for individuals with gastroesophageal disorders that require long-term use of PPIs.
    MeSH term(s) Humans ; Proton Pump Inhibitors/adverse effects ; Genetic Predisposition to Disease ; Celiac Disease/chemically induced ; Celiac Disease/genetics ; Omeprazole
    Chemical Substances Proton Pump Inhibitors ; HLA-DQ8 antigen ; Omeprazole (KG60484QX9)
    Language English
    Publishing date 2023-09-22
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.171: Show issues Location:
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  10. Article: Integrins Can Act as Suppressors of Ras-Mediated Oncogenesis in the

    Martínez-Abarca Millán, Ana / Martín-Bermudo, María D

    Cancers

    2023  Volume 15, Issue 22

    Abstract: Cancer is the second leading cause of death worldwide. Key to cancer initiation and progression is the crosstalk between cancer cells and their microenvironment. The extracellular matrix (ECM) is a major component of the tumour microenvironment and ... ...

    Abstract Cancer is the second leading cause of death worldwide. Key to cancer initiation and progression is the crosstalk between cancer cells and their microenvironment. The extracellular matrix (ECM) is a major component of the tumour microenvironment and integrins, main cell-ECM adhesion receptors, are involved in every step of cancer progression. However, accumulating evidence has shown that integrins can act as tumour promoters but also as tumour suppressor factors, revealing that the biological roles of integrins in cancer are complex. This incites a better understating of integrin function in cancer progression. To achieve this goal, simple model organisms, such as
    Language English
    Publishing date 2023-11-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15225432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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