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Article ; Online: Reason-Based Recommendations From a Developmental Systems Approach for Students With Needs Across Functional Domains.

McCarty, Tara V / Miller, Carol A

Language, speech, and hearing services in schools

2023 Volume 54, Issue 3, Page(s) 831–840

Abstract: Purpose: This tutorial aims to introduce school-based speech-language pathologists (SLPs) to developmental systems theory as a framework for considering interactions across functional domains, such as language, vision, and motor, for students with ... ...

Abstract	Purpose: This tutorial aims to introduce school-based speech-language pathologists (SLPs) to developmental systems theory as a framework for considering interactions across functional domains, such as language, vision, and motor, for students with complex needs. Method: This tutorial summarizes the current literature on developmental systems theory in its application to working with students who have needs in multiple domains of functioning in addition to communication. A hypothetical case of a student, James, with cerebral palsy, cortical visual impairment, and complex communication needs, is presented to illustrate the primary tenets of the theory. Results: Specific reason-based recommendations are presented that SLPs can put to practice with their own caseload in direct response to the three tenets of developmental systems theory. Conclusions: A developmental systems approach will be useful in expanding SLP knowledge of where to begin and how to best serve children with language, motor, vision, and other concomitant needs. The tenets, including sampling, context dependency, and interdependency, and the application of developmental systems theory can be instrumental in providing a way forward for SLPs struggling with the assessment and intervention of students with complex needs.
MeSH term(s)	Child ; Humans ; Students ; Communication Disorders ; Language ; Communication ; Systems Analysis ; Speech-Language Pathology/education ; Speech
Language	English
Publishing date	2023-04-14
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2067619-0
ISSN	1558-9129 ; 0161-1461
ISSN (online)	1558-9129
ISSN	0161-1461
DOI	10.1044/2023_LSHSS-22-00144
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Speech production factors and verbal working memory in children and adults with developmental language disorder.

Poll, Gerard H / Miller, Carol A

Applied psycholinguistics

2021 Volume 42, Issue 3, Page(s) 673–702

Abstract: Verbal working memory (VWM) deficits are common in individuals with developmental language disorder (DLD) but are not well understood. This study evaluated how both memory and language production factors influence VWM performance in children and adults ... ...

Abstract	Verbal working memory (VWM) deficits are common in individuals with developmental language disorder (DLD) but are not well understood. This study evaluated how both memory and language production factors influence VWM performance in children and adults with DLD, focusing on the influence of serial position, phonological activation (PA), and lexical frequency. Participants were 30 children with DLD and 26 with typical language (TL), and 21 adults with DLD and 23 with TL. The participants completed a listening span task in which they were asked to recall the final words of sentences in sets of increasing size. Responses (dependent variable) were coded as correct, incorrect, or no response. Final words were coded for frequency, serial position within the set, and PA (number of occurrences of the initial phoneme, vowel, and whole word in the task). These variables, along with age and language status, were entered as predictors in mixed-effects multinomial regression models. Extreme serial position, greater PA, and higher frequency reduced incorrect and no responses. These effects were attenuated for the DLD group, and the effect of greater PA varied with set size. The findings suggest that for individuals with DLD, VWM performance is affected by more limited effective language experience and by the dynamic task demands.
Language	English
Publishing date	2021-02-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1499968-7
ISSN	1469-1817 ; 0142-7164
ISSN (online)	1469-1817
ISSN	0142-7164
DOI	10.1017/s0142716421000011
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Article ; Online: Utilization and Perception of Peer-Support After Lower Limb Loss in the United States: Potential Benefits on Mobility Outcomes.

Lee, Szu-Ping / Maluotoga, Moriah / Thind, Roopkiran / Lindsay, Lise / Bhatta, Tirth / Miller, Carol A

Archives of physical medicine and rehabilitation

2024

Abstract: Objective: To examine participants' experiences with peer-support after lower limb loss (LLL) and the associations between the peer-support experience (perceived benefits and barriers) and mobility outcomes.: Design: Quantitative and qualitative ... ...

Abstract	Objective: To examine participants' experiences with peer-support after lower limb loss (LLL) and the associations between the peer-support experience (perceived benefits and barriers) and mobility outcomes. Design: Quantitative and qualitative descriptive study with a cross-sectional design. Setting: National survey (distributed to 169 peer-support groups in 44 states in the US). Participants: The survey was completed by 82 individuals with a major lower limb amputation (53% female, 54% over 55 years of age; N=82). Main outcome measures: A 32-item survey to examine respondents' experiences in peer-support activities. Prosthetic mobility was measured using the Prosthetic Limb Users Survey of Mobility (PLUS-M). Results: Two out of 3 respondents received some forms of peer-support after amputation. Among them 75% reported peer-support having a positive effect on their outlook on life, and 78% reported that information gained from peer-support was helpful. Companionship, altruistic acts, and gaining information on how to cope with amputation were the top themes of why respondents enjoyed the peer-support experience. Nearly all (94%) respondents would recommend peer-support to other people with LLL. Individuals who received peer-support exhibited a trend of greater mobility (55th vs 36th percentile on PLUS-M; P=.055). Conclusion: Individuals with LLL reported generally positive experiences regarding their engagement in peer-support activities. Peer-support groups are viewed as a helpful source for both information and emotional support, potentially benefiting functional and psychological recovery after amputation. Individuals who have received peer-support also exhibited greater mobility.
Language	English
Publishing date	2024-01-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	80057-0
ISSN	1532-821X ; 0003-9993
ISSN (online)	1532-821X
ISSN	0003-9993
DOI	10.1016/j.apmr.2023.12.009
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Article ; Online: Considering proceduralization through the lens of adolescents with developmental language disorders: Commentary on Kamhi (2019).

Poll, Gerard H / Miller, Carol A

Journal of communication disorders

2019 Volume 83, Page(s) 105940

MeSH term(s)	Adolescent ; Comprehension ; Humans ; Language Development Disorders
Language	English
Publishing date	2019-09-17
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	3011-9
ISSN	1873-7994 ; 0021-9924
ISSN (online)	1873-7994
ISSN	0021-9924
DOI	10.1016/j.jcomdis.2019.105940
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Book: Elder abuse and nursing

Miller, Carol A

what nurses need to know and can do about it

2017

Author's details	Carol A.Miller
MeSH term(s)	Elder Abuse/prevention & control ; Geriatric Nursing/methods ; Elder Abuse/diagnosis
Language	English
Size	xx, 337 pages :, illustrations
Document type	Book
ISBN	9780826131522 ; 9780826131539 ; 0826131522 ; 0826131530
Database	Catalogue of the US National Library of Medicine (NLM)

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Article ; Online: Event-related potentials reveal that bilinguals are more efficient in resolving conflict than monolinguals.

Botezatu, Mona Roxana / Miller, Carol A / Johnson, Jaclyn / Misra, Maya

Neuroreport

2021 Volume 32, Issue 8, Page(s) 721–726

Abstract: In the current study, we evaluated behavioral and electrophysiological evidence to determine whether bilinguals differ from monolinguals in the efficiency of response inhibition. Bilinguals and matched monolingual controls performed the flanker task ... ...

Abstract	In the current study, we evaluated behavioral and electrophysiological evidence to determine whether bilinguals differ from monolinguals in the efficiency of response inhibition. Bilinguals and matched monolingual controls performed the flanker task while behavioral and electrophysiological measures were collected. Participants were slower and less accurate in responding to incongruent trials, but the magnitude of the behavioral effect of congruence was not modulated by participant group. The electrophysiological data revealed a biphasic N200/P300 signature. Incongruent trials elicited a larger N200 response, followed by a larger P300 response than congruent trials. The mean amplitude of the N200 component, a marker of conflict detection, was not modulated by group, suggesting that monolinguals and bilinguals did not differ on the ability to detect conflict. However, the mean amplitude of the P300 component, an index of response inhibition, was smaller in bilinguals than monolinguals. This indicates that bilinguals may be more efficient in resolving response conflict relative to monolinguals. Even though the two groups do not differ in behavioral task performance, the event-related potential (ERP) data suggest that monolinguals may be working harder to reach similar patterns of performance as bilinguals. The P300 magnitude correlated positively with picture naming latencies and negatively with Operation Span scores, suggesting that the ERP response to nonlinguistic conflict resolution may capture individual differences in language proficiency and cognitive resources.
MeSH term(s)	Adolescent ; Adult ; Cerebral Cortex/physiology ; Electroencephalography ; Evoked Potentials/physiology ; Female ; Humans ; Language ; Male ; Multilingualism ; Negotiating ; Reaction Time/physiology ; Young Adult
Language	English
Publishing date	2021-04-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1049746-8
ISSN	1473-558X ; 0959-4965
ISSN (online)	1473-558X
ISSN	0959-4965
DOI	10.1097/WNR.0000000000001645
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Article ; Online: Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer's disease cortex.

Melnik, Mikhail / Miyoshi, Emily / Ma, Ricky / Corrada, Maria / Kawas, Claudia / Bohannan, Ryan / Caraway, Chad / Miller, Carol A / Hinman, Jason D / John, Varghese / Bilousova, Tina / Gylys, Karen H

Journal of neuroscience methods

2024 Volume 406, Page(s) 110137

Abstract: Background: The neuronal and gliaI populations within the brain are tightly interwoven, making isolation and study of large populations of a single cell type from brain tissue a major technical challenge. Concurrently, cell-type specific extracellular ... ...

Abstract	Background: The neuronal and gliaI populations within the brain are tightly interwoven, making isolation and study of large populations of a single cell type from brain tissue a major technical challenge. Concurrently, cell-type specific extracellular vesicles (EVs) hold enormous diagnostic and therapeutic potential in neurodegenerative disorders including Alzheimer's disease (AD). New method: Postmortem AD cortical samples were thawed and gently dissociated. Following filtration, myelin and red blood cell removal, cell pellets were immunolabeled with fluorescent antibodies and analyzed by flow cytometry. The cell pellet supernatant was applied to a triple sucrose cushion for brain EV isolation. Results: Neuronal, astrocyte and microglial cell populations were identified. Cell integrity was demonstrated using calcein AM, which is retained by cells with esterase activity and an intact membrane. For some experiments cell pellets were fixed, permeabilized, and immunolabeled for cell-specific markers. Characterization of brain small EV fractions showed the expected size, depletion of EV negative markers, and enrichment in positive and cell-type specific markers. Comparison with existing methods and conclusions: We optimized and integrated established protocols, aiming to maximize information obtained from each human autopsy brain sample. The uniqueness of our method lies in its capability to isolate cells and EVs from a single cryopreserved brain sample. Our results not only demonstrate the feasibility of isolating specific brain cell subpopulations for RNA-seq but also validate these subpopulations at the protein level. The accelerated study of EVs from human samples is crucial for a better understanding of their contribution to neuron/glial crosstalk and disease progression.
MeSH term(s)	Humans ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Extracellular Vesicles/metabolism ; Cryopreservation/methods ; Cerebral Cortex/cytology ; Cerebral Cortex/metabolism ; Neurons/metabolism ; Aged ; Male ; Female ; Astrocytes/metabolism ; Aged, 80 and over ; Cell Separation/methods ; Flow Cytometry/methods ; Microglia/metabolism
Language	English
Publishing date	2024-04-14
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	282721-9
ISSN	1872-678X ; 0165-0270
ISSN (online)	1872-678X
ISSN	0165-0270
DOI	10.1016/j.jneumeth.2024.110137
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Book: Nursing for wellness in older adults

Miller, Carol A

2015

Author's details	Carol A. Miller
MeSH term(s)	Geriatric Nursing ; Aged/psychology ; Health Promotion ; Nursing Theory
Language	English
Size	p. ;, cm. ; xxvii, 626 pages :, illustrations.
Edition	Seventh edition.
Document type	Book
ISBN	9781451190830 ; 1451190832
Database	Catalogue of the US National Library of Medicine (NLM)

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Article ; Online: Auditory processing theories of language disorders: past, present, and future.

Miller, Carol A

Language, speech, and hearing services in schools

2011 Volume 42, Issue 3, Page(s) 309–319

Abstract: Purpose: The purpose of this article is to provide information that will assist readers in understanding and interpreting research literature on the role of auditory processing in communication disorders.: Method: A narrative review was used to ... ...

Abstract	Purpose: The purpose of this article is to provide information that will assist readers in understanding and interpreting research literature on the role of auditory processing in communication disorders. Method: A narrative review was used to summarize and synthesize the literature on auditory processing deficits in children with auditory processing disorder (APD), specific language impairment (SLI), and dyslexia. The history of auditory processing theories of these 3 disorders is described, points of convergence and controversy within and among the different branches of research literature are considered, and the influence of research on practice is discussed. The theoretical and clinical contributions of neurophysiological methods are also reviewed, and suggested approaches for critical reading of the research literature are provided. Conclusion: Research on the role of auditory processing in communication disorders springs from a variety of theoretical perspectives and assumptions, and this variety, combined with controversies over the interpretation of research results, makes it difficult to draw clinical implications from the literature. Neurophysiological research methods are a promising route to better understanding of auditory processing. Progress in theory development and its clinical application is most likely to be made when researchers from different disciplines and theoretical perspectives communicate clearly and combine the strengths of their approaches.
MeSH term(s)	Adolescent ; Auditory Perceptual Disorders/diagnosis ; Auditory Perceptual Disorders/physiopathology ; Auditory Perceptual Disorders/therapy ; Brain/physiopathology ; Cerebral Cortex/physiopathology ; Child ; Dyslexia/diagnosis ; Dyslexia/physiopathology ; Dyslexia/therapy ; Evoked Potentials/physiology ; Forecasting ; Hearing Tests ; Humans ; Language Development Disorders/diagnosis ; Language Development Disorders/physiopathology ; Language Development Disorders/therapy ; Magnetic Resonance Imaging ; Speech-Language Pathology/trends ; Young Adult
Language	English
Publishing date	2011-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2067619-0
ISSN	1558-9129 ; 0161-1461
ISSN (online)	1558-9129
ISSN	0161-1461
DOI	10.1044/0161-1461(2011/10-0040)
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Article: Older Adults' Perceived Barriers to Participation in a Falls Prevention Strategy.

Fernandes, Júlio Belo / Fernandes, Sónia Belo / Almeida, Ana Silva / Vareta, Diana Alves / Miller, Carol A

Journal of personalized medicine

2021 Volume 11, Issue 6

Abstract: There is a need to increase older adults' access and adherence to falls prevention strategies. This study aims to explore older adults' perceived barriers to participation in a fall prevention strategy. A qualitative descriptive approach was used. Semi- ... ...

Abstract	There is a need to increase older adults' access and adherence to falls prevention strategies. This study aims to explore older adults' perceived barriers to participation in a fall prevention strategy. A qualitative descriptive approach was used. Semi-structured interviews were conducted with 18 older adult users of a Day Care Unit from a Private Institution of Social Solidarity in the region of Lisbon and Tagus Valley in Portugal. The recruitment was made in September 2019. The interviews were recorded transcribed verbatim and analysed thematically using the method of constant comparisons. The barriers to participation in a fall prevention strategy are healthcare system gaps, social context, economic context, health status, psychological capability, and lack of knowledge to demystify myths and misconceptions about falls. There are different barriers to participate in a fall prevention strategy. It is urgent to eliminate or reduce the effect of these barriers to increase older adults' participation in fall prevention strategies.
Language	English
Publishing date	2021-05-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm11060450
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