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  1. Article ; Online: Stereotactic Body Radiation Therapy for Spine Metastases-Findings from an Australian Population-Based Study.

    Ong, Wee Loon / Milne, Roger L / Foroudi, Farshad / Millar, Jeremy L

    Current oncology (Toronto, Ont.)

    2023  Volume 30, Issue 8, Page(s) 7777–7788

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Male ; Humans ; Radiosurgery ; Australia ; Radiation Oncology ; Melanoma ; Pain
    Language English
    Publishing date 2023-08-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol30080564
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4305: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Socio-economic and ethnocultural influences on geographical disparities in breast cancer screening participation in Victoria, Australia.

    Stuart, Geoffrey W / Chamberlain, James A / Milne, Roger L

    Frontiers in oncology

    2022  Volume 12, Page(s) 980879

    Abstract: Objective: To examine the socio-economic and ethnocultural characteristics of geographical areas that may influence variation in breast cancer screening participation.: Methods: In a cross-sectional analysis breast cancer screening participation for ... ...

    Abstract Objective: To examine the socio-economic and ethnocultural characteristics of geographical areas that may influence variation in breast cancer screening participation.
    Methods: In a cross-sectional analysis breast cancer screening participation for statistical areas in Victoria, Australia (2015-2017) was linked with data from the 2016 Australian Census. We selected four commonly used area-level measures of socio-economic status from the Australian Census (i) income (ii) educational level (iii) occupational status and (iv) employment profile. To assess the ethnocultural characteristics of statistical areas we used the Census measures (i) country of birth (ii) language spoken at home (iii) fluency in English (iv) religion and (v) the proportion of immigrants in an area, together with their recency of migration.
    Results: All the selected measures were related to screening participation. There was a high degree of association both within and between socio-economic and ethnocultural characteristics of areas as they relate to screening. Ethnocultural characteristics alone accounted for most of the explained geographical disparity in screening participation.
    Conclusions: Geographical disparities in breast cancer screening participation may be due to ethnocultural factors that are confounded with socio-economic factors.
    Language English
    Publishing date 2022-11-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.980879
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  3. Article ; Online: Factors Explaining Inequalities in Colon Cancer Survival-Reply.

    Afshar, Nina / Milne, Roger L / English, Dallas R

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

    2022  Volume 31, Issue 1, Page(s) 297

    MeSH term(s) Colonic Neoplasms/epidemiology ; Health Status Disparities ; Humans ; Socioeconomic Factors
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1153420-5
    ISSN 1538-7755 ; 1055-9965
    ISSN (online) 1538-7755
    ISSN 1055-9965
    DOI 10.1158/1055-9965.EPI-21-1129
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3693: Show issues Location:
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  4. Article ; Online: Physical Activity, Sedentary Behavior, and Pancreatic Cancer Risk: A Mendelian Randomization Study.

    Gentiluomo, Manuel / Dixon-Suen, Suzanne C / Farinella, Riccardo / Peduzzi, Giulia / Canzian, Federico / Milne, Roger L / Lynch, Brigid M / Campa, Daniele

    Journal of the Endocrine Society

    2024  Volume 8, Issue 4, Page(s) bvae017

    Abstract: Pancreatic cancer is currently the seventh leading cause of cancer death worldwide. Understanding whether modifiable factors increase or decrease the risk of this disease is central to facilitating primary prevention. Several epidemiological studies have ...

    Abstract Pancreatic cancer is currently the seventh leading cause of cancer death worldwide. Understanding whether modifiable factors increase or decrease the risk of this disease is central to facilitating primary prevention. Several epidemiological studies have described the benefits of physical activity, and the risks associated with sedentary behavior, in relation to cancer. This study aimed to assess evidence of causal effects of physical activity and sedentary behavior on pancreatic cancer risk. We conducted a two-sample Mendelian randomization study using publicly available data for genetic variants associated with physical activity and sedentary behavior traits and genetic data from the Pancreatic Cancer Cohort Consortium (PanScan), the Pancreatic Cancer Case-Control Consortium (PanC4), and the FinnGen study for a total of 10 018 pancreatic cancer cases and 266 638 controls. We also investigated the role of body mass index (BMI) as a possible mediator between physical activity and sedentary traits and risk of developing pancreatic cancer. We found evidence of a causal association between genetically determined hours spent watching television (hours per day) and increased risk of pancreatic cancer for each hour increment (PanScan-PanC4 odds ratio = 1.52, 95% confidence interval 1.17-1.98,
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2472-1972
    ISSN (online) 2472-1972
    DOI 10.1210/jendso/bvae017
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  5. Article ; Online: Body Size, Diet Quality, and Epigenetic Aging: Cross-Sectional and Longitudinal Analyses.

    Li, Danmeng Lily / Hodge, Allison M / Cribb, Lachlan / Southey, Melissa C / Giles, Graham G / Milne, Roger L / Dugué, Pierre-Antoine

    The journals of gerontology. Series A, Biological sciences and medical sciences

    2024  Volume 79, Issue 4

    Abstract: Epigenetic age is an emerging marker of health that is highly predictive of disease and mortality risk. There is a lack of evidence on whether lifestyle changes are associated with changes in epigenetic aging. We used data from 1 041 participants in the ... ...

    Abstract Epigenetic age is an emerging marker of health that is highly predictive of disease and mortality risk. There is a lack of evidence on whether lifestyle changes are associated with changes in epigenetic aging. We used data from 1 041 participants in the Melbourne Collaborative Cohort Study with blood DNA methylation measures at baseline (1990-1994, mean age: 57.4 years) and follow-up (2003-2007, mean age: 68.8 years). The Alternative Healthy Eating Index-2010 (AHEI-2010), the Mediterranean Dietary Score, and the Dietary Inflammatory Index were used as measures of diet quality, and weight, waist circumference, and waist-to-hip ratio as measures of body size. Five age-adjusted epigenetic aging measures were considered: GrimAge, PhenoAge, PCGrimAge, PCPhenoAge, and DunedinPACE. Multivariable linear regression models including restricted cubic splines were used to assess the cross-sectional and longitudinal associations of body size and diet quality with epigenetic aging. Associations between weight and epigenetic aging cross-sectionally at both time points were positive and appeared greater for DunedinPACE (per SD: β ~0.24) than for GrimAge and PhenoAge (β ~0.10). The longitudinal associations with weight change were markedly nonlinear (U-shaped) with stable weight being associated with the lowest epigenetic aging at follow-up, except for DunedinPACE, for which only weight gain showed a positive association. We found negative, linear associations for AHEI-2010 both cross-sectionally and longitudinally. Other adiposity measures and dietary scores showed similar results. In middle-aged to older adults, declining diet quality and weight gain may increase epigenetic age, while the association for weight loss may require further investigation. Our study sheds light on the potential of weight management and dietary improvement in slowing aging processes.
    MeSH term(s) Humans ; Aged ; Middle Aged ; Cohort Studies ; Cross-Sectional Studies ; Body Mass Index ; Diet ; Aging/genetics ; Weight Gain ; Waist Circumference ; Epigenesis, Genetic
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1223643-3
    ISSN 1758-535X ; 1079-5006
    ISSN (online) 1758-535X
    ISSN 1079-5006
    DOI 10.1093/gerona/glae026
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    Uc I Zs.242/A: Show issues Location:
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  6. Article ; Online: Bilateral Salpingo-Oophorectomy to Reduce Breast Cancer Risk in Women With Germline BRCA1 or BRCA2 Pathogenic Variants-Caution Needed.

    Conduit, Ciara / Milne, Roger L / Phillips, Kelly-Anne

    JAMA oncology

    2021  Volume 7, Issue 9, Page(s) 1401

    MeSH term(s) BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Female ; Germ Cells ; Humans ; Salpingo-oophorectomy
    Chemical Substances BRCA1 Protein ; BRCA1 protein, human ; BRCA2 Protein ; BRCA2 protein, human
    Language English
    Publishing date 2021-06-30
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2021.2037
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  7. Article ; Online: Factors Explaining Socio-Economic Inequalities in Cancer Survival: A Systematic Review.

    Afshar, Nina / English, Dallas R / Milne, Roger L

    Cancer control : journal of the Moffitt Cancer Center

    2021  Volume 28, Page(s) 10732748211011956

    Abstract: Background: There is strong and well-documented evidence that socio-economic inequality in cancer survival exists within and between countries, but the underlying causes of these differences are not well understood.: Methods: We systematically ... ...

    Abstract Background: There is strong and well-documented evidence that socio-economic inequality in cancer survival exists within and between countries, but the underlying causes of these differences are not well understood.
    Methods: We systematically searched the Ovid Medline, EMBASE, and CINAHL databases up to 31 May 2020. Observational studies exploring pathways by which socio-economic position (SEP) might causally influence cancer survival were included.
    Results: We found 74 eligible articles published between 2005 and 2020. Cancer stage, other tumor characteristics, health-related lifestyle behaviors, co-morbidities and treatment were reported as key contributing factors, although the potential mediating effect of these factors varied across cancer sites. For common cancers such as breast and prostate cancer, stage of disease was generally cited as the primary explanatory factor, while co-morbid conditions and treatment were also reported to contribute to lower survival for more disadvantaged cases. In contrast, for colorectal cancer, most studies found that stage did not explain the observed differences in survival by SEP. For lung cancer, inequalities in survival appear to be partly explained by receipt of treatment and co-morbidities.
    Conclusions: Most studies compared regression models with and without adjusting for potential mediators; this method has several limitations in the presence of multiple mediators that could result in biased estimates of mediating effects and invalid conclusions. It is therefore essential that future studies apply modern methods of causal mediation analysis to accurately estimate the contribution of potential explanatory factors for these inequalities, which may translate into effective interventions to improve survival for disadvantaged cancer patients.
    MeSH term(s) Female ; Health Status Indicators ; Healthcare Disparities/statistics & numerical data ; Humans ; Male ; Neoplasms/mortality ; Neoplasms/therapy ; Primary Health Care/statistics & numerical data ; Socioeconomic Factors ; Survival Rate
    Language English
    Publishing date 2021-04-30
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 1328503-8
    ISSN 1526-2359 ; 1073-2748
    ISSN (online) 1526-2359
    ISSN 1073-2748
    DOI 10.1177/10732748211011956
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4467: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article ; Online: Differences in treatment choices for localised prostate cancer diagnosed in private and public health services.

    Te Marvelde, Luc / Milne, Roger L / Haines, Ian E

    The Medical journal of Australia

    2021  Volume 214, Issue 10, Page(s) 486–486.e1

    MeSH term(s) Humans ; Male ; Patient Selection ; Prostatectomy ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/therapy ; United States ; United States Public Health Service
    Language English
    Publishing date 2021-05-11
    Publishing country Australia
    Document type Letter ; Comment
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.51073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.398: Show issues Location:
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  9. Article ; Online: Palliative radiotherapy for bone metastases at the end of life in Victoria.

    Ong, Wee Loon / Foroudi, Farshad / Milne, Roger L / Millar, Jeremy L

    The Medical journal of Australia

    2021  Volume 214, Issue 5, Page(s) 236–237.e1

    MeSH term(s) Aged ; Aged, 80 and over ; Bone Neoplasms/radiotherapy ; Bone Neoplasms/secondary ; Breast Neoplasms/pathology ; Breast Neoplasms/radiotherapy ; Female ; Humans ; Logistic Models ; Lung Neoplasms/pathology ; Lung Neoplasms/radiotherapy ; Male ; Middle Aged ; Multivariate Analysis ; Palliative Care/methods ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/radiotherapy ; Quality of Life ; Radiotherapy/statistics & numerical data ; Radiotherapy Dosage ; Registries ; Victoria
    Language English
    Publishing date 2021-02-20
    Publishing country Australia
    Document type Letter
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.50954
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.398: Show issues Location:
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  10. Article ; Online: Bilateral Salpingo-oophorectomy and Breast Cancer Risk for

    Conduit, Ciara / Milne, Roger L / Friedlander, Michael L / Phillips, Kelly-Anne

    Cancer prevention research (Philadelphia, Pa.)

    2021  Volume 14, Issue 11, Page(s) 983–994

    Abstract: Without preventive interventions, women with germline pathogenic variants ... ...

    Abstract Without preventive interventions, women with germline pathogenic variants in
    MeSH term(s) BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/prevention & control ; Female ; Genetic Predisposition to Disease ; Humans ; Mutation ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/prevention & control ; Ovariectomy ; Risk ; Salpingo-oophorectomy/methods
    Chemical Substances BRCA1 Protein ; BRCA1 protein, human ; BRCA2 Protein ; BRCA2 protein, human
    Language English
    Publishing date 2021-08-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2434717-6
    ISSN 1940-6215 ; 1940-6207
    ISSN (online) 1940-6215
    ISSN 1940-6207
    DOI 10.1158/1940-6207.CAPR-21-0141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6766: Show issues Location:
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