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  1. Article ; Online: Failure of placentation and pregnancy complications: The role of feto-maternal immune balance.

    Milosevic Stevanovic, Jelena / Krstic, Miljan / Vukomanovic, Predrag / Kutlesic, Ranko / Trajkovic, Sonja Pop / Simic, Dusan

    European journal of obstetrics, gynecology, and reproductive biology

    2024  Volume 295, Page(s) 126–135

    MeSH term(s) Pregnancy ; Female ; Humans ; Placentation ; Placenta ; Pregnancy Complications/etiology
    Language English
    Publishing date 2024-02-12
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2024.02.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cervical molar pregnancy, profuse bleeding and urgent surgical treatment.

    Vukomanovic, Predrag / Kutlesic, Ranko / Milosevic Stevanovic, Jelena / Djordjevic, Ivana / Stefanovic, Milan

    Ginekologia polska

    2022  Volume 94, Issue 4, Page(s) 337–338

    MeSH term(s) Pregnancy ; Female ; Humans ; Pregnancy, Ectopic/surgery ; Cervix Uteri ; Hydatidiform Mole/surgery ; Hysterectomy
    Language English
    Publishing date 2022-07-27
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 130894-4
    ISSN 2543-6767 ; 0017-0011
    ISSN (online) 2543-6767
    ISSN 0017-0011
    DOI 10.5603/GP.a2022.0024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Potential role of d-

    Simic, Dusan / Nikolic Turnic, Tamara / Dimitrijevic, Aleksandra / Zivadinovic, Aleksandar / Milosevic-Stevanovic, Jelena / Djuric, Dusan / Zivkovic, Vladimir / Jakovljevic, Vladimir

    Canadian journal of physiology and pharmacology

    2022  Volume 100, Issue 7, Page(s) 629–636

    Abstract: d- ...

    Abstract d-
    MeSH term(s) Female ; Humans ; Inositol/pharmacology ; Inositol/therapeutic use ; Insulin ; Insulin Resistance ; Oxidative Stress ; Polycystic Ovary Syndrome ; Testosterone
    Chemical Substances Insulin ; Testosterone (3XMK78S47O) ; Inositol (4L6452S749)
    Language English
    Publishing date 2022-04-12
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 127527-6
    ISSN 1205-7541 ; 0008-4212
    ISSN (online) 1205-7541
    ISSN 0008-4212
    DOI 10.1139/cjpp-2021-0766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prognostic Impact of Canonical TGF-β Signaling in Urothelial Bladder Cancer.

    Stojnev, Slavica / Krstić, Miljan / Čukuranović Kokoris, Jovana / Conić, Irena / Petković, Ivan / Ilić, Sonja / Milosević-Stevanović, Jelena / Veličković, Ljubinka Janković

    Medicina (Kaunas, Lithuania)

    2019  Volume 55, Issue 6

    Abstract: Background and ... ...

    Abstract Background and objectives
    MeSH term(s) Biomarkers, Tumor/analysis ; Biomarkers, Tumor/blood ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Predictive Value of Tests ; Prognosis ; Proportional Hazards Models ; Serbia ; Smad2 Protein/analysis ; Smad2 Protein/blood ; Smad4 Protein/analysis ; Smad4 Protein/blood ; Transforming Growth Factor beta1/analysis ; Transforming Growth Factor beta1/blood ; Urinary Bladder Neoplasms/blood
    Chemical Substances Biomarkers, Tumor ; SMAD2 protein, human ; SMAD4 protein, human ; Smad2 Protein ; Smad4 Protein ; Transforming Growth Factor beta1
    Language English
    Publishing date 2019-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina55060302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: T lymphocytes in the third trimester decidua in preeclampsia.

    Milosevic-Stevanovic, Jelena / Krstic, Miljan / Stefanovic, Milan / Zivadinovic, Radomir / Vukomanovic, Predrag / Trajkovic-Dinic, Sonja Pop / Stojnev, Slavica

    Hypertension in pregnancy

    2019  Volume 38, Issue 1, Page(s) 52–57

    Abstract: Objective: The aim of study was to conduct immunohistochemical quantification of CD3+ and CD8+ decidual lymphocytes in preeclampsia.: Methods: A study group included 30 cases of preeclampsia and a control group included 20 healthy pregnant women, all ...

    Abstract Objective: The aim of study was to conduct immunohistochemical quantification of CD3+ and CD8+ decidual lymphocytes in preeclampsia.
    Methods: A study group included 30 cases of preeclampsia and a control group included 20 healthy pregnant women, all delivered by Cesarean section. Samples of placental bed were analyzed after immunohistochemical staining of CD45+, CD3+ and CD8+ cells.
    Results: The group with preeclampsia included a significantly higher number of CD3+ (p < 0.01) and CD8+ (p < 0.05) T lymphocytes.
    Conclusion: It is certain that thebalance dysregulation of T cell of the immune milieu of deciduais of importance in etiopathogenesis and manifestations of preeclampsia.
    MeSH term(s) Adult ; CD3 Complex/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Case-Control Studies ; Decidua/metabolism ; Female ; Humans ; Lymphocyte Count ; Placenta/metabolism ; Pre-Eclampsia/metabolism ; Pregnancy ; Pregnancy Trimester, Third/metabolism ; Prospective Studies ; T-Lymphocytes/metabolism ; Young Adult
    Chemical Substances CD3 Complex
    Language English
    Publishing date 2019-02-11
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1151886-8
    ISSN 1525-6065 ; 1064-1955
    ISSN (online) 1525-6065
    ISSN 1064-1955
    DOI 10.1080/10641955.2019.1575393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Number of decidual natural killer cells & macrophages in pre-eclampsia.

    Milosevic-Stevanovic, Jelena / Krstic, Miljan / Radovic-Janosevic, Dragana / Popovic, Jasmina / Tasic, Marija / Stojnev, Slavica

    The Indian journal of medical research

    2016  Volume 144, Issue 6, Page(s) 823–830

    Abstract: Background & objectives: The process of human placentation is complex and still not well understood. This study was aimed to examine the relationship between clinical features of pre-eclampsia and degree of trophoblastic invasion after its ... ...

    Abstract Background & objectives: The process of human placentation is complex and still not well understood. This study was aimed to examine the relationship between clinical features of pre-eclampsia and degree of trophoblastic invasion after its immunohistochemical visualization in the context of possible alterations in the number of natural killer (NK) cells and macrophages in the decidua.
    Methods: This prospective study included a study group comprising 30 pregnant women with pre-eclampsia delivered by caesarean section and a control group comprising 20 healthy pregnant women also delivered by caesarean section. Samples of placental bed obtained during caesarean section were analyzed after immunohistochemical labelling CD56 + NK cells, CD68 + macrophages and cytokeratin 7 trophoblastic cells.
    Results: In pre-eclampsia, there was a significantly lower number of CD56 + NK cells in the decidua (P<0.001) and a higher number of CD68 + macrophages (P<0.001) compared to control group. In the subgroup of pre-eclampsia with intrauterine growth retardation (IUGR), a significantly greater number of NK cells (P<0.05) was recorded, as well as an increased number of macrophages, but not significantly compared to pre-eclampsia without IUGR. There was no significant difference in the distribution of these cells in the decidua in relation to the severity of pre-eclampsia. CD56 + NK cells were significantly less (P<0.05) and macrophages were more (P<0.05) in the group with poor trophoblastic invasion.
    Interpretation & conclusions: Alterations in the number of immune cells in relation to the degree of trophoblastic invasion indicated their role in aetiopathogenesis of pre-eclampsia, while the direct association between their number and severity of pre-eclampsia was not confirmed.
    Language English
    Publishing date 2016-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_776_15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Preeclampsia with and without intrauterine growth restriction-Two pathogenetically different entities?

    Milosevic-Stevanovic, Jelena / Krstic, Miljan / Radovic-Janosevic, Dragana / Stefanovic, Milan / Antic, Vladimir / Djordjevic, Ivana

    Hypertension in pregnancy

    2016  Volume 35, Issue 4, Page(s) 573–582

    Abstract: Objective: The objective of this study is to determine the differences in histopathological features of basal decidua and placenta in cases of preeclampsia with or without fetal intrauterine growth restriction (IUGR).: Methods: A prospective case- ... ...

    Abstract Objective: The objective of this study is to determine the differences in histopathological features of basal decidua and placenta in cases of preeclampsia with or without fetal intrauterine growth restriction (IUGR).
    Methods: A prospective case-control study included a study group consisting of 30 pregnant women with preeclampsia completed by cesarean section (CS), in 19 of whom preeclampsia was associated with IUGR, and in 11 it was not. The control group consisted of 20 healthy pregnant women delivered by elective CS. Placentas and samples of placental bed obtained during CS were histopathologically (HP) analyzed after hematoxylin-eosin staining and immunohistochemical labeling of Cytokeratin 7 (CK7) trophoblastic cells in decidua.
    Results: Regarding the HP changes in the spiral arteries in preeclampsia, the most frequent features were inadequate transformation of spiral arteries with poor trophoblastic invasion (70.0%) and fibrinoid necrosis of the media (66.7%), and rarely acute atherosis (33.3%) and thrombosis (30.0%). Villous hypermaturity was more frequently found in placentas of patients with preeclampsia with IUGR (p < 0.05), while there were no differences between subgroups of preeclampsia with and without IUGR regarding some of HP alterations of placental bed.
    Conclusion: Alterations of the placental bed in terms of decidual vasculopathy are more the characteristics of the preeclampsia itself than IUGR, while changes in placental villi primarily follow the presence of IUGR, which could indicate that preeclampsia with and without IUGR are two pathogenetically different entities.
    Language English
    Publishing date 2016-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1151886-8
    ISSN 1525-6065 ; 1064-1955
    ISSN (online) 1525-6065
    ISSN 1064-1955
    DOI 10.1080/10641955.2016.1212872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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