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Article ; Online: Resilience and (Dis)empowerment

Bei Ju / Hai Min Dai / Todd L. Sandel

SAGE Open, Vol

Use of Social Media Among Female Mainland Low-Skilled Workers in Macao During the COVID-19 Pandemic

2023 Volume 13

Abstract: The role of social media in a resilient process is associated with the co-constitution of structural forces and users’ agency. During COVID-19, how women—particularly low-skilled labor migrants—used social media for empowerment is underexplored. By ... ...

Abstract	The role of social media in a resilient process is associated with the co-constitution of structural forces and users’ agency. During COVID-19, how women—particularly low-skilled labor migrants—used social media for empowerment is underexplored. By taking a socio-techno approach, this study qualitatively examines mobile phone-based social media usage among female mainland low-skilled workers in Macao when coping with the pandemic. The enabling yet constraining role of social media has been identified through semi-structured interviews. Social media use is a double-edged sword: on the one hand, social media is appropriated to relieve stress and anxiety, open access to updated COVID-19 related information, and manage contagious risks; on the other hand, it reinforces existing constraints and thus hinders resilience, due to female migrant workers’ high risk of addictive social media use and limited information literacy. Moving beyond the Information and Communication Technology empowerment, a more inclusive approach is recommended in the long term to cope with the risks and uncertainties posed by the pandemic.
Keywords	History of scholarship and learning. The humanities ; AZ20-999 ; Social Sciences ; H
Subject code	300
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Molecular Dynamics Simulation of the Effect of Low Temperature on the Properties of Lignocellulosic Amorphous Region

Xuewei Jiang / Wei Wang / Yuanyuan Guo / Min Dai

Forests, Vol 14, Iss 1208, p

2023 Volume 1208

Abstract: In this paper, a molecular model of cellulose amorphous region-water molecule was developed using Materials Studio software by applying the molecular dynamics method. The effect of low temperature on the properties of the lignocellulosic amorphous region, ...

Abstract	In this paper, a molecular model of cellulose amorphous region-water molecule was developed using Materials Studio software by applying the molecular dynamics method. The effect of low temperature on the properties of the lignocellulosic amorphous region, the main component of wood, was investigated in an attempt to explain the macroscopic property changes from a microscopic perspective and to provide a theoretical basis for the safe use of wood and wood products in low-temperature environments and other related areas of research. Dynamic simulations were carried out at 20 °C, 0 °C, −30 °C, −70 °C, −110 °C and −150 °C for the NPT combinations to obtain the energy, volume, density, and hydrogen bonding change trends of their models, respectively. The changes in the microstructure of the water molecule–cellulose amorphous region model were analyzed, and the mechanical properties were calculated. The results showed that the interaction between the amorphous cellulose region and water molecules was enhanced as the temperature decreased, the density of the models increased, and the volume decreased. The number of total hydrogen bonds and the number of hydrogen bonds between water molecule–cellulose chains increased for each model, and the decrease in temperature made the cellulose molecular activities weaker. The values of G , E , and K increased with the decrease in temperature, and K / G decreased with the decrease in temperature. It shows that the decrease in temperature is beneficial to enhance the mechanical properties of the amorphous region of cellulose and increases the stiffness of the material. However, the toughness and plasticity decrease when the temperature is too low.
Keywords	cellulose amorphous region ; low temperature treatment ; mechanical properties ; molecular dynamics ; Plant ecology ; QK900-989
Subject code	541
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Application of Graphene Oxide-Based Hydrogels in Bone Tissue Engineering.

Zhihui, Kuang / Min, Dai

ACS biomaterials science & engineering

2022 Volume 8, Issue 7, Page(s) 2849–2857

Abstract: As an important derivative of graphene-based materials, graphene oxide (GO) not only plays an important role not only in optoelectronics and sensing but also in biology due to its unique mechanical, electronic, and optical properties. This article ... ...

Abstract	As an important derivative of graphene-based materials, graphene oxide (GO) not only plays an important role not only in optoelectronics and sensing but also in biology due to its unique mechanical, electronic, and optical properties. This article reviews the application of GO-based hydrogels in bone tissue engineering. Whether it is a hydrogel synthesized with natural polymer compounds, synthetic polymer chemicals, bioceramics, bioactive factors, or other materials, the addition of GO can significantly improve various properties of the hydrogel. We also introduce some high-performance GO-based hydrogels in this paper, proposing some insights into materials that may be applied to bone tissue engineering in the future.
MeSH term(s)	Graphite ; Hydrogels/chemistry ; Polymers ; Tissue Engineering
Chemical Substances	Hydrogels ; Polymers ; graphene oxide ; Graphite (7782-42-5)
Language	English
Publishing date	2022-06-27
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2373-9878
ISSN (online)	2373-9878
DOI	10.1021/acsbiomaterials.2c00396
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Paeonol Attenuates Atherosclerosis by Inhibiting Vascular Smooth Muscle Cells Senescence via SIRT1/P53/TRF2 Signaling Pathway

Min Zhou / Xiaolin Ma / Menglong Gao / Hongfei Wu / Yarong Liu / Xiaoyan Shi / Min Dai

Molecules, Vol 29, Iss 1, p

2024 Volume 261

Abstract: Atherosclerosis is a chronic inflammatory disease leading to various vascular diseases. Vascular smooth muscle cell (VSMC) senescence promotes atherosclerotic inflammation and the formation of plaque necrosis core, in part through telomere damage ... ...

Abstract	Atherosclerosis is a chronic inflammatory disease leading to various vascular diseases. Vascular smooth muscle cell (VSMC) senescence promotes atherosclerotic inflammation and the formation of plaque necrosis core, in part through telomere damage mediated by a high-fat diet. Our previous research found that paeonol, a potential anti-inflammatory agent extracted from Cortex Moutan, could significantly improve VSMCs dysfunction. However, the impact of paeonol on the senescence of VSMCs remains unexplored. This study presents the protective effects of paeonol on VSMCs senescence, and its potential activity in inhibiting the progression of atherosclerosis in vivo and in vitro. Sirtuin 1 (SIRT1) is a nuclear deacetylase involved in cell proliferation, senescence, telomere damage, and inflammation. Here, SIRT1 was identified as a potential target of paeonol having anti-senescence and anti-atherosclerosis activity. Mechanistic studies revealed that paeonol binds directly to SIRT1 and then activates the SIRT1/P53/TRF2 pathway to inhibit VSMCs senescence. Our results suggested that SIRT1-mediated VSMCs senescence is a promising druggable target for atherosclerosis, and that pharmacological modulation of the SIRT1/P53/TRF2 signaling pathway by paeonol is of potential benefit for patients with atherosclerosis.
Keywords	paeonol ; atherosclerosis ; vascular smooth muscle cells ; cell senescence ; SIRT1 ; Organic chemistry ; QD241-441
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Phylogeny of Rhynchium and Its Related Genera (Hymenoptera

Min Dai / Shu-Lin He / Bin Chen / Ting-Jing Li

Insects, Vol 14, Iss 775, p

Eumeninae) Based on Universal Single-Copy Orthologs and Ultraconserved Elements

2023 Volume 775

Abstract: The subfamily Eumeninae is a large group of fierce predatory insects that prey mainly on the larvae of Lepidoptera pests. Because of the highly similar morphologies of the genus Rhynchium and its related genera in the subfamily, including Rhynchium ... ...

Abstract	The subfamily Eumeninae is a large group of fierce predatory insects that prey mainly on the larvae of Lepidoptera pests. Because of the highly similar morphologies of the genus Rhynchium and its related genera in the subfamily, including Rhynchium Spinola, Allorhynchium van der Vecht, Anterhynchium de Saussure, Pararrhynchium de Saussure, it is essential to delineate their relationships. A previous phylogenetic analysis based on mitochondrial genomes suggested the inconsistent relationships of these genera under traditional classification based on morphological characters. In this study, we first used single-copy orthologs [USCO] and ultraconserved elements [UCE] extracted from 10 newly sequenced low-coverage whole genomes to resolve the phylogenetic relationships of the above genera. The newly sequenced genomes are 152.99 Mb to 211.49 Mb in size with high completeness (BUSCO complete: 91.5–95.6%) and G + C content (36.31–38.76%). Based on extracted 5811 USCOs and 2312 UCEs, the phylogenetic relationships of Rhynchium and its related genera were: (( Allorhynchium + Lissodynerus ) + ( Pararrhynchium + ( Anterhynchium + ( Dirhynchium + Rhynchium )))), which was consistent with the mitochondrial genome results. The results supported the genus Rhynchium as monophyletic, whereas Anterhynchium was recovered as paraphyletic, with Anterhynchium ( Dirhynchium ) as a sister to Rhynchium and hence deserving generic status; In addition, in the genus Pararrhynchium , P. septemfasciatus feanus and P. venkataramani were separated, not clustered on a branch, just as P. septemfasciatus feanus was not together with P. striatum based on mitochondrial genomes. Since Lissodynerus septemfasciatus , the type species of the genus Lissodynerus , was transferred to Pararrhynchium , it is considered that the genus Lissodynerus should be restituted as a valid genus, not a synonym of Pararrhynchium .
Keywords	Eumeninae ; low-coverage whole genomes ; universal single-copy orthologs [USCO] ; ultraconserved elements [UCE] ; phylogeny ; Science ; Q
Subject code	590
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Tracking inter-annual terrestrial water storage variations over Lake Baikal basin from GRACE and GRACE Follow-On missions

Min Wei / Hao Zhou / Zhicai Luo / Min Dai

Journal of Hydrology: Regional Studies, Vol 40, Iss , Pp 101004- (2022)

2022

Abstract: The Gravity Recovery and Climate Experiment (GRACE) mission and its follow-on mission (GRACE Follow-On) can accurately track the Earth’s mass variations, which have been successfully used in various geoscience researches related to global and regional ... ...

Abstract	The Gravity Recovery and Climate Experiment (GRACE) mission and its follow-on mission (GRACE Follow-On) can accurately track the Earth’s mass variations, which have been successfully used in various geoscience researches related to global and regional hydrological process. In this study, satellite gravimetry (GRACE and GRACR Follow-On) and hydrological model (GLDAS) are used to estimate the TWS variations over LBB in 2003–2020. As the world’s largest freshwater lake by volume, the terrestrial water storage (TWS) variations in Lake Baikal basin (LBB) significantly affect the surrounding ecological environment. However, the spatial scale of LBB is relatively small when compared to approximately 300 km spatial resolution of GRACE and GRACE Follow-On mission. Therefore, the forward modeling method is used to alleviate the leakage errors during satellite gravimetry data processing. To assess the performance of forward modeling method, a close-loop simulation study is designed in noise-contaminated condition. The simulation results demonstrate the feasibility of forward modeling method in accurately estimating TWS variations over LBB. After appropriate leakage correction, the inter-annual TWS from satellite gravimetry agrees well with GLDAS. The TWS variations over LBB demonstrate that (1) there are drastic variations and periodic characteristics around 4–5 years, and the drought events are observed in 2003, 2007, 2011 and 2015 as relatively smaller TWSs. (2) The soil moisture and groundwater are the major contributors to TWS variations (with the correlation coefficient of 0.88 and 0.89), and the surface water is the main contributor to the seasonal variations over LBB. (3) The TWS presents about 6 moths delay to precipitation variations, while the precipitation is still the major driver to affect the hydrological processes over this region.
Keywords	Lake Baikal basin ; GRACE/GRACE Follow-On ; Terrestrial water storage ; Forward modeling method ; GLDAS ; CRU ; Physical geography ; GB3-5030 ; Geology ; QE1-996.5
Subject code	550
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Eltrombopag for the treatment of refractory thrombocytopenia associated with connective tissue disease

Juan Wang / Min Dai / Qiong Fu / Sheng Chen

Scientific Reports, Vol 11, Iss 1, Pp 1-

2021 Volume 8

Abstract: Abstract To assess the efficacy and safety of eltrombopag in connective tissue disease (CTD)-immune thrombocytopenia (ITP), we conducted this single-center retrospective observational study, including patients with refractory CTD-ITP who were treated ... ...

Abstract	Abstract To assess the efficacy and safety of eltrombopag in connective tissue disease (CTD)-immune thrombocytopenia (ITP), we conducted this single-center retrospective observational study, including patients with refractory CTD-ITP who were treated with eltrombopag between January 2018 and August 2019. The characteristics of patients at baseline, and the efficacy and safety of the drug were analyzed. The predictors for a response were analyzed using a univariate analysis such as Chi-square or nonparametric test and a multiple correspondence analysis (MCA) method. A total of 15 patients with refractory CTD-ITP were included in the study. Their median age at the time of inclusion was 40.6 years. The median platelet count at initiation of eltrombopag was 11.53 × 109/L. The median remission time was 3.42 weeks. The complete remission (CR) and overall response rate decreased with time. The factors that associated with response to eltrombopag in patients with CTD-ITP were protopathy, WBC counts, levels of hemoglobin, and characteristics of bone marrow findings in univariate analysis. In addition, MCA indicated that a poor response to eltrombopag in patients with refractory CTD-ITP was closely associated with a protopathy with SS, medium to severe degree of anemia, leukopenia, and bone marrow aspiration showing aplastic anemia, an absence of megakaryocytes or macrophage activation syndrome (MAS). In conclusion, eltrombopag was effective and well-tolerated in patients with CTD-associated thrombocytopenia. Some factors should be considered in the use of eltrombopag, including the protopathy, blood test, and bone marrow histology.
Keywords	Medicine ; R ; Science ; Q
Subject code	616
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Clinical Features and Laboratory Examination Results of Sjogren’s Syndrome Complicated with Thyroid Disorders

Min Dai / Jing Wang / Qian Huang

Journal of Healthcare Engineering, Vol

A Retrospective Analysis

2021 Volume 2021

Abstract: Objective. To analyze the clinical incidence, clinical manifestations, laboratory examination, and complications of Sjogren’s syndrome complicated with thyroid disorders in patients and to explore the clinical significance of its occurrence and ... ...

Abstract	Objective. To analyze the clinical incidence, clinical manifestations, laboratory examination, and complications of Sjogren’s syndrome complicated with thyroid disorders in patients and to explore the clinical significance of its occurrence and concurrence relationship. Methods. The clinical manifestations, thyroid function, antithyroid antibodies, immunology indicators, autoantibodies, and routine laboratory examination items of 201 patients with Sjogren’s syndrome in Chongqing Hospital of Traditional Chinese Medicine were reviewed and analyzed. According to whether the thyroid function was abnormal or not, the patients were divided into the group of Sjogren’s syndrome complicated with abnormal thyroid function (n = 36) and the group of Sjogren’s syndrome without abnormal thyroid function (n = 165). The clinical symptoms and test indicators of the two groups were compared. Results. Among 201 patients with Sjogren’s syndrome, 36 patients had abnormal thyroid function (17.9%) and 36 patients with abnormal thyroid function had hypothyroidism. The abnormal renal function, decreased Hb, decreased WBC, increased ESR, and decreased C4 were more significant in the group with Sjogren’s syndrome complicated with abnormal thyroid function, which had significant differences compared with the group with normal thyroid function (P<0.05). The positive rates of aTG and aTPO in patients with Sjogren’s syndrome complicated with thyroid disorders were higher than that in the normal group, and the difference between the two groups was statistically significant (P<0.05). Conclusion. Patients with Sjogren’s syndrome are often associated with hypothyroidism, and these patients may have more severe immune disorders, anemia, leukopenia, and renal involvement. The results show that paying attention to the detection of thyroid function in patients with Sjogren’s syndrome may be of positive significance to judge the condition and prognosis.
Keywords	Medicine (General) ; R5-920 ; Medical technology ; R855-855.5
Subject code	610
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
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Article ; Online: A review on quality control, toxicity and clinical application of Amomum tsao-ko Crevost & Lemarié

Zhong-hui Pu / Bao-shan Wang / Si-yuan Zhang / Feng-hui Sun / Min Dai

Pharmacological Research - Modern Chinese Medicine, Vol 5, Iss , Pp 100165- (2022)

2022

Abstract: The dried fruit of Amomum tsao-ko Crevost & Lemarié, a perennial herb of Cardamom in Zingiberaceae, has been widely used in food and as a folk medicine. It is used not only as an important food additive and spice for removing peculiar smell and improving ...

Abstract	The dried fruit of Amomum tsao-ko Crevost & Lemarié, a perennial herb of Cardamom in Zingiberaceae, has been widely used in food and as a folk medicine. It is used not only as an important food additive and spice for removing peculiar smell and improving taste, but also as a traditional Chinese medicine with significant efficacy in treating many kinds of disorders. Based on the high edible and medicinal value, large amounts of investigation have been reported for A. tsaoko in the past several years. This review specifically summarises its quality control, toxicology and clinical application, about which no literature had systematically reviewed, based on our best acknowledge. The current quality control of A. tsaoko is based on the content of volatile oil, which should be no less than 1.4% according to the Pharmacopoeia of the People's Republic of China (2020 edition), while a more possible Q-Markers should be developed to focus on either a specific bioactive ingredient or a component correlated with a certain clinical efficacy. Toxicity research suggests that A. tsaoko actually belongs to the non-toxic substance, although citral and 1,8-cineole, two main components of A. tsaoko, is hepatotoxic for the former and displays low acute toxicity and sub-chronic oral toxicity for the latter, but no obviously accumulative toxicity has so far been discovered for A. tsaoko. In clinical practice, A. tsaoko is often used in treatment of dampness/cold resistance, malaria, vomiting, fullness and epigastric distension across additional disorders, such as SARS, COVID-19 and hepatitis.
Keywords	Amomum tsao-ko Crevost & ; Lemarié ; Quality control ; Toxicity ; Clinical application ; Other systems of medicine ; RZ201-999 ; Therapeutics. Pharmacology ; RM1-950
Subject code	590
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Difference of Lead Accumulation and Transport in Different Ecotypes of Miscanthus floridulus

Jianqiao Qin / Huarong Zhao / Hao Liu / Min Dai / Peng Zhao / Xi Chen / Xiange Wu

Processes, Vol 10, Iss 2219, p

2022 Volume 2219

Abstract: Miscanthus floridulus is a plant with a high biomass and heavy metal tolerance, which is a good candidate for phytoremediation. Pot experiments were conducted to compare the growth response, Pb enrichment ability, and the effect on Pb speciation of two ... ...

Abstract	Miscanthus floridulus is a plant with a high biomass and heavy metal tolerance, which is a good candidate for phytoremediation. Pot experiments were conducted to compare the growth response, Pb enrichment ability, and the effect on Pb speciation of two ecotypes of M. floridulus from the Dabaoshan Mining Area and the non-mining area of Boluo County, Huizhou, in soils with different Pb contents. The results showed that two ecotypes of M. floridulus had different growth responses to Pb concentrations in soil. Under a low concentration of Pb (100 mg·kg −1 ) treatment, the aboveground biomass of the non-mining area plant ecotype was significantly affected, while the plants with the mining area ecotype were not significantly affected. When the concentration of Pb increased, the aboveground biomass of the non-mining ecotype was 30.2–41.1% of the control, while that of the mining ecotype was 57.8–65.0% of the control. The root biomass of the non-mining ecotype decreased with the increase of treatment concentration, accounting for 57.8–64.2% of the control, while that of the mining ecotype increased significantly, accounting for 119.5–138.6% of the control. The Pb content in the shoots and roots of the mining ecotype M. floridulus increased rapidly with the increase of the Pb treatment concentration in the soil, and the increase in speed was obviously faster than that of the non-mining ecotype. The total amount of Pb accumulated in the roots of the ecotype from the mining area was much greater than that of the ecotype from the non-mining area, and increased significantly with the increase of Pb concentration in the soil ( p < 0.05). With the aggravation of Pb stress, the transfer coefficient and tolerance index of the two ecotypes decreased by different degrees. The transfer coefficient and tolerance index of the mining ecotype were significantly higher than those of the non-mining ecotype. Pearson correlation analysis showed that root biomass was positively correlated with shoot biomass, and shoot biomass was ...
Keywords	lead ; miscanthus floridulus ; ecotype ; accumulation and translocation ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
Subject code	580
Language	English
Publishing date	2022-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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