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  1. Article: Trends in research related to ophthalmic microperimetry from 1992 to 2022: A bibliometric analysis and knowledge graph study.

    Ming, Jing / Qin, Rui

    Frontiers in medicine

    2023  Volume 9, Page(s) 1024336

    Abstract: Background: Microperimetry is a novel technology to assess macular function. The aim of the study was to explore the global research status and trends in microperimetry.: Methods: Documents related to microperimetry in ophthalmology from 1992 to 2022 ...

    Abstract Background: Microperimetry is a novel technology to assess macular function. The aim of the study was to explore the global research status and trends in microperimetry.
    Methods: Documents related to microperimetry in ophthalmology from 1992 to 2022 were extracted from the Science Citation Index Expanded (SCI-E) database of the Web of Science Core Collection (WOSCC). Raw data were analyzed using the VOSviewer and CiteSpace software. Bibliometric parameters included annual publication quantity, countries, authors, journals, international cooperation, and keywords.
    Results: A total of 1,217 peer-reviewed documents were retrieved. Annual research output has increased significantly since 2005, especially since 2013. Holz F, Rubin G, and Guymer R contributed most to the number of articles published about microperimetry. Rubin G, Fitzke F, and Holz F, respectively, received the most citations for their study. The countries publishing most were the USA, Italy, and the UK, while the USA, the UK, and Germany received the most citation frequency. Univ Bonn, UCL, and Moorfields Eye Hosp were the top three productive institutions for microperimetry research in the world. The top three journals that publish articles about microperimetry were Retina-The Journal of Retinal and Vitreous Diseases, Investigative Ophthalmology and Visual Science, and the American Journal of Ophthalmology. The top 10 common keywords included microperimetry, optical coherence tomography, eye, retinal sensitivity, macular degeneration, fundus autofluorescence, scanning laser ophthalmoscope, visual acuity, sensitivity, and degeneration. Keywords "optical coherence tomography angiography," "retinitis pigmentosa," and "internal limiting membrane" burst in the last 3 years.
    Conclusion: The bibliometric and knowledge graph analysis of research status and trends in microperimetry provided global researchers with valuable information to propose future cooperation and track cutting-edge progress.
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.1024336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Malignant Syphilis.

    Liu, Ming J / Lv, Wei

    The New England journal of medicine

    2023  Volume 388, Issue 21, Page(s) 1991

    MeSH term(s) Humans ; Syphilis/complications ; Syphilis/diagnosis ; Syphilis/drug therapy
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMicm2213894
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Clinical decision support tool for breast cancer recurrence prediction using SHAP value in cooperative game theory.

    Liu, Ying / Fu, Yating / Peng, Yadong / Ming, Jie

    Heliyon

    2024  Volume 10, Issue 2, Page(s) e24876

    Abstract: Background: Recurrence remains the primary cause of death in patients with breast cancer. Although machine learning can efficiently predict the prognosis of breast cancer patients, the black-box nature of the model may result in a lack of evidence for ... ...

    Abstract Background: Recurrence remains the primary cause of death in patients with breast cancer. Although machine learning can efficiently predict the prognosis of breast cancer patients, the black-box nature of the model may result in a lack of evidence for clinicians when making critical decisions.
    Methods: In this study, our main objective was twofold: (1) to develop a clinical decision support tool for predicting the prognosis of breast cancer and (2) to identify and explore the key factors that influence breast cancer recurrence. To achieve this, we employed an explainable ensemble learning method called Shapley additive explanation (SHAP), which leverages cooperative game theory. Using real-world data from 1629 breast cancer patients, we analyzed and uncovered the key factors associated with breast cancer recurrence. Subsequently, we used these identified factors to create a recurrence prediction model and establish a decision mechanism for the tool. The proposed method not only provides accurate recurrence predictions but also offers transparent explanations for these predictions.
    Results: By utilizing four key factors, namely, tumor size, clinical stage III, number of lymph node metastases, and age, our decision support tool for predicting breast cancer recurrence achieved significant improvements. The extra-tree model exhibited an increased area under the receiver operating characteristic curve (AUC) of 0.97, while the Random Forest model demonstrated an improved AUC of 0.96. We also offer a decision mechanism for a recurrence prediction model based on the identified key factors. This transparent and interpretable decision-making process facilitated by our explainable ensemble learning model enhances trust and promotes its applicability in clinical settings.
    Conclusions: The proposed explainable ensemble learning method shows promising results in predicting breast cancer recurrence, outperforming existing methods with high accuracy and transparency. This advancement has the potential to significantly improve clinical decision-making and patient outcomes in breast cancer treatment.
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Kinetic Resolution of P-Chiral Phosphindole Oxides through Rhodium-Catalyzed Asymmetric Arylation.

    Li, Wen-Cong / Ming, Jialin / Chen, Shufeng

    Organic letters

    2024  

    Abstract: Highly efficient kinetic resolution of P-chiral phosphindole oxides via rhodium-catalyzed asymmetric arylation under mild conditions is described. Selectivity factors of up to 569 were achieved by employing ... ...

    Abstract Highly efficient kinetic resolution of P-chiral phosphindole oxides via rhodium-catalyzed asymmetric arylation under mild conditions is described. Selectivity factors of up to 569 were achieved by employing chiral
    Language English
    Publishing date 2024-05-01
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.4c01252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Development of a multiplex RT-PCR assay for simultaneous detection of Lily symptomless virus, Lily mottle virus, Cucumber mosaic virus, and Plantago asiatica mosaic virus in Lilies.

    Xu, Leifeng / Ming, Jun

    Virology journal

    2022  Volume 19, Issue 1, Page(s) 219

    Abstract: Background: Viral pathogens causing significant economic losses in lilies (Lilium spp. and hybrids) include Lily symptomless virus (LSV), Lily mottle virus (LMoV), Cucumber mosaic virus (CMV), and Plantago asiatica mosaic virus (PlAMV). Rapid and ... ...

    Abstract Background: Viral pathogens causing significant economic losses in lilies (Lilium spp. and hybrids) include Lily symptomless virus (LSV), Lily mottle virus (LMoV), Cucumber mosaic virus (CMV), and Plantago asiatica mosaic virus (PlAMV). Rapid and efficient virus detection methods are pivotal to prevent the spread of these viruses.
    Results: In this study, four specific primer pairs designed from conserved regions of genomic sequences of each virus were used to amplify a 116 bp product for LSV, a 247 bp product for LMoV, a 359 bp product for CMV, and a 525 bp product for PlAMV in a multiplex reverse transcription-polymerase chain reaction (multiplex RT-PCR). The amplified products were clearly separated by 2% agarose gel electrophoresis. The optimal reaction annealing temperature and cycle number were 53.8 °C and 35, respectively. The developed multiplex RT-PCR method was then used to test virus infections from lily samples collected from different regions of China.
    Conclusions: An effective multiplex RT-PCR assay was established for the simultaneous detection and differentiation of LSV, LMoV, CMV, and PlAMV in lilies, which offers a useful tool for routine molecular diagnosis and epidemiological studies of these viruses.
    MeSH term(s) Lilium/genetics ; Cucumovirus/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Potyvirus/genetics ; Cytomegalovirus Infections ; Plant Diseases
    Language English
    Publishing date 2022-12-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2160640-7
    ISSN 1743-422X ; 1743-422X
    ISSN (online) 1743-422X
    ISSN 1743-422X
    DOI 10.1186/s12985-022-01947-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: N7-Methylguanosine-Related lncRNAs: Integrated Analysis Associated With Prognosis and Progression in Clear Cell Renal Cell Carcinoma.

    Ming, Jie / Wang, Chunyang

    Frontiers in genetics

    2022  Volume 13, Page(s) 871899

    Abstract: N7-Methylguanosine (m7G) and long non-coding RNAs (lncRNAs) have been widely reported to play an important role in cancer. However, there is little known about the relationship between m7G-related lncRNAs and clear cell renal cell carcinoma (ccRCC). To ... ...

    Abstract N7-Methylguanosine (m7G) and long non-coding RNAs (lncRNAs) have been widely reported to play an important role in cancer. However, there is little known about the relationship between m7G-related lncRNAs and clear cell renal cell carcinoma (ccRCC). To find new potential biomarkers and construct an m7G-related lncRNA prognostic signature for ccRCC, we retrieved transcriptome data and clinical data from The Cancer Genome Atlas (TCGA), and divided the entire set into train set and test set with the ratio of 1:1 randomly. The m7G-related lncRNAs were identified by Pearson correlation analysis (|coefficients| > 0.4, and
    Language English
    Publishing date 2022-04-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.871899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The role of circadian rhythm in osteoporosis; a review.

    Tian, Yihao / Ming, Jian

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 960456

    Abstract: Osteoporosis is characterized by a high incidence rate, with significant effects on people's lives. The underlying mechanisms are complex, with no treatments for the condition. Recent studies have indicated that melatonin can be used to treat ... ...

    Abstract Osteoporosis is characterized by a high incidence rate, with significant effects on people's lives. The underlying mechanisms are complex, with no treatments for the condition. Recent studies have indicated that melatonin can be used to treat osteoporosis by promoting osteoblast proliferation and differentiation, and inhibiting osteoclast differentiation. Specifically,
    Language English
    Publishing date 2022-09-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.960456
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  8. Article: Green marketing orientation impact on business performance: Case of pharmaceutical industry of Pakistan.

    Shaukat, Fatima / Ming, Jia

    Frontiers in psychology

    2022  Volume 13, Page(s) 940278

    Abstract: This study is based on the natural resource based view, which examines the impact of holistic marketing orientation on business performance (BP) by defining the role of enablers and mediators. The drivers, including corporate social responsibility (CSR) ... ...

    Abstract This study is based on the natural resource based view, which examines the impact of holistic marketing orientation on business performance (BP) by defining the role of enablers and mediators. The drivers, including corporate social responsibility (CSR) and environmental culture (EC) influence, are tested by analyzing the role of sustainable competitive advantage (SCA) as a mediator. The analysis is based on 298 samples collected from top and middle-level managers working in the pharmaceutical industry. Structural equation modeling was undertaken using Smart PLS 3.2.8. The research outcomes reveal that corporate social responsibility and environmental culture have a substantial impact on green marketing orientation (GMO). The results show that GMO has a significant direct and indirect impact on business performance while a full mediation of sustainable competitive advantage exists between the green marketing orientation and business performance. The outcomes will facilitate managers in green marketing strategy and decision making in the long-term, with 3-fold benefits in addition to strengthening their competitiveness.
    Language English
    Publishing date 2022-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.940278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Melatonin inhibits osteoclastogenesis via RANKL/OPG suppression mediated by Rev-Erbα in osteoblasts.

    Tian, Yihao / Ming, Jian

    Journal of cellular and molecular medicine

    2022  Volume 26, Issue 14, Page(s) 4032–4047

    Abstract: Diabetic osteoporosis is secondary osteoporosis and a serious complication of diabetes with a high incidence rate and poor prognosis. The specific mechanism of diabetic osteoporosis is unclear, and prevention and treatment options are limited. Recently, ... ...

    Abstract Diabetic osteoporosis is secondary osteoporosis and a serious complication of diabetes with a high incidence rate and poor prognosis. The specific mechanism of diabetic osteoporosis is unclear, and prevention and treatment options are limited. Recently, melatonin has been found to prevent and treat diabetic osteoporosis. Herein, we investigated the mechanism whereby melatonin inhibits osteoclastogenesis and identified a new target for osteoporosis treatment. We established an in vitro osteoblast-osteoclast co-culture system as a diabetic osteoporosis model. Osteoclastogenesis was determined using tartrate-resistant acid phosphatase staining and cathepsin K expression. Real-time PCR was used to ascertain expression of microRNA mir-882, targeting Rev-Erbα. Western blotting was performed to detect the expression of Rev-Erbα, receptor activator of NF-kB ligand (RANKL), and osteoprotegerin (OPG), and ELISA was utilized to analyse the secreted form of RANKL. High glucose promoted osteoclastogenesis and elevated the RANKL/OPG ratio in osteoblasts, while melatonin reversed these effects. High glucose inhibited Rev-Erbα expression, while melatonin promoted its expression. Conversely, high glucose promoted mir-882 expression, while melatonin inhibited it. We infer that melatonin inhibits RANKL expression in osteoblasts via the mir-882/Rev-Erbα axis, thus inhibiting osteoclastogenesis. Our findings provide insights into diabetic osteoporosis and identify a new therapeutic target for osteoporosis.
    MeSH term(s) Cell Differentiation ; Glucose/metabolism ; Humans ; Ligands ; Melatonin/metabolism ; Melatonin/pharmacology ; Osteoblasts/metabolism ; Osteoclasts/metabolism ; Osteogenesis/genetics ; Osteoporosis/drug therapy ; Osteoporosis/genetics ; Osteoporosis/metabolism ; Osteoprotegerin/genetics ; Osteoprotegerin/metabolism ; RANK Ligand/metabolism
    Chemical Substances Ligands ; Osteoprotegerin ; RANK Ligand ; Glucose (IY9XDZ35W2) ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2022-06-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2074559-X
    ISSN 1582-4934 ; 1582-4934 ; 1582-1838
    ISSN (online) 1582-4934
    ISSN 1582-4934 ; 1582-1838
    DOI 10.1111/jcmm.17440
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5752: Show issues Location:
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  10. Article ; Online: A study of two different valve types of peripherally inserted central catheters for 5-fluorouracil pumping in chemotherapy patients with gastrointestinal tumors.

    Chen, Wei-Fen / Li, Yin-Ling / Ming, Jie / Yu, Wen-Qin

    Asian journal of surgery

    2024  Volume 47, Issue 4, Page(s) 1955–1956

    MeSH term(s) Humans ; Fluorouracil ; Catheterization, Central Venous ; Catheters, Indwelling/adverse effects ; Gastrointestinal Neoplasms/drug therapy
    Chemical Substances Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2024-01-11
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.12.157
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