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  1. Article ; Online: Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen

    Zhijian Li / Christoph Kuppe / Susanne Ziegler / Mingbo Cheng / Nazanin Kabgani / Sylvia Menzel / Martin Zenke / Rafael Kramann / Ivan G. Costa

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 14

    Abstract: scATAC-Seq yields data that is extremely sparse. Here, the authors present a computationally efficient imputation method called scOpen that improves the downstream analyses of scATAC-Seq data and use it to identify transcriptional regulators of kidney ... ...

    Abstract scATAC-Seq yields data that is extremely sparse. Here, the authors present a computationally efficient imputation method called scOpen that improves the downstream analyses of scATAC-Seq data and use it to identify transcriptional regulators of kidney fibrosis.
    Keywords Science ; Q
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Next-Generation Morphometry for pathomics-data mining in histopathology

    David L. Hölscher / Nassim Bouteldja / Mehdi Joodaki / Maria L. Russo / Yu-Chia Lan / Alireza Vafaei Sadr / Mingbo Cheng / Vladimir Tesar / Saskia V. Stillfried / Barbara M. Klinkhammer / Jonathan Barratt / Jürgen Floege / Ian S. D. Roberts / Rosanna Coppo / Ivan G. Costa / Roman D. Bülow / Peter Boor

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Volume 14

    Abstract: Pathology diagnostics still rely on tissue morphology assessment by trained experts. Here, the authors perform deep-learning-based segmentation followed by large-scale feature extraction of histological images, i.e., next-generation morphometry, to ... ...

    Abstract Pathology diagnostics still rely on tissue morphology assessment by trained experts. Here, the authors perform deep-learning-based segmentation followed by large-scale feature extraction of histological images, i.e., next-generation morphometry, to enable outcome-relevant and disease-specific pathomics analysis of non-tumor kidney pathology.
    Keywords Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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