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Article: Genetic structure of the endemic

Minh Nguyen, Duc / Lan Phan Nguyen, Hong / Minh Nguyen, Tam

2022 Volume 14, Issue 2, Page(s) plac007

Abstract: Anthropogenic disturbances in tropical forests often affect the genetic diversity of a species. ...

Abstract	Anthropogenic disturbances in tropical forests often affect the genetic diversity of a species.
Language	English
Publishing date	2022-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2555823-7
ISSN	2041-2851
ISSN	2041-2851
DOI	10.1093/aobpla/plac007
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Investigation and prediction of the extensional viscosity of okra mucilage using the Giesekus model.

Minh, Nguyen Ngoc

Biorheology

2022 Volume 59, Issue 1-2, Page(s) 29–42

Abstract: Background: Okra is a vegetable that is widely grown around the world. Okra mucilage contains a high mucus concentration that can be useful for supporting the swallowing process. Although the extensional rheology of okra mucilage is essential to its ... ...

Abstract	Background: Okra is a vegetable that is widely grown around the world. Okra mucilage contains a high mucus concentration that can be useful for supporting the swallowing process. Although the extensional rheology of okra mucilage is essential to its flow, its extensional viscosity has not received much attention. Objective: Using a filament stretching rheometer, the extensional viscosity of the mucilage in okra was examined. The Giesekus model was used to predict this parameter. Methods: The okra mucilage with different concentrations was extracted from fresh okra. The extensional viscosity was measured using a filament breakup apparatus. The diameter of the liquid bridge was measured by a laser micrometer and it was also observed by a high-speed camera. A rotational rheometer was used to measure the shear viscosity. In addition, the master curves for the shear viscosity were plotted to eliminate the influence of solvent and shear rate and evaluate the influence of concentration on the elasticity of okra mucilage. The okra mucilage shear and extensional viscosity were predicted using the Giesekus model. Results: Every sample of okra mucilage exhibited shear thinning behavior. In addition to having a high extensional viscosity that is hundreds of times higher than its shear viscosity, okra mucilage also exhibited stretching phenomena. The master curves demonstrated that the pseudoplasticity of the okra mucilage increased along with the concentration. The rheological behavior of the mucilage in okra can be explained by the Giesekus model. Conclusions: Okra mucilage's shear viscosity exhibited shear thinning behavior and a strong extensional viscosity that was significantly higher than its shear viscosity. The shear and extensional viscosity of okra mucilage can be described and predicted using the Giesekus model.
MeSH term(s)	Abelmoschus ; Viscosity ; Polysaccharides ; Elasticity ; Rheology
Chemical Substances	Polysaccharides
Language	English
Publishing date	2022-09-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	82015-5
ISSN	1878-5034 ; 0006-355X
ISSN (online)	1878-5034
ISSN	0006-355X
DOI	10.3233/BIR-220006
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Article ; Online: Hedgehog Pathway Inhibitors as Targeted Cancer Therapy and Strategies to Overcome Drug Resistance

Ngoc Minh Nguyen / Jungsook Cho

International Journal of Molecular Sciences, Vol 23, Iss 1733, p

2022 Volume 1733

Abstract: Hedgehog (Hh) signaling is a highly conserved pathway that plays a vital role during embryonic development. Recently, uncontrolled activation of this pathway has been demonstrated in various types of cancer. Therefore, Hh pathway inhibitors have emerged ... ...

Abstract	Hedgehog (Hh) signaling is a highly conserved pathway that plays a vital role during embryonic development. Recently, uncontrolled activation of this pathway has been demonstrated in various types of cancer. Therefore, Hh pathway inhibitors have emerged as an important class of anti-cancer agents. Unfortunately, however, their reputation has been tarnished by the emergence of resistance during therapy, necessitating clarification of mechanisms underlying the drug resistance. In this review, we briefly overview canonical and non-canonical Hh pathways and their inhibitors as targeted cancer therapy. In addition, we summarize the mechanisms of resistance to Smoothened (SMO) inhibitors, including point mutations of the drug binding pocket or downstream molecules of SMO, and non-canonical mechanisms to reinforce Hh pathway output. A distinct mechanism involving loss of primary cilia is also described to maintain GLI activity in resistant tumors. Finally, we address the main strategies to circumvent the drug resistance. These strategies include the development of novel and potent inhibitors targeting different components of the canonical Hh pathway or signaling molecules of the non-canonical pathway. Further studies are necessary to avoid emerging resistance to Hh inhibitors and establish an optimal customized regimen with improved therapeutic efficacy to treat various types of cancer, including basal cell carcinoma.
Keywords	hedgehog signaling ; hedgehog inhibitor ; smoothened inhibitor ; basal cell carcinoma ; drug resistance ; targeted cancer therapy ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	616
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Moving Target Defense-Based Denial-of-Service Mitigation in Cloud Environments

Minh Nguyen / Saptarshi Debroy

Security and Communication Networks, Vol

A Survey

2022 Volume 2022

Abstract: With the increased frequency and intensity of denial-of-service (DoS) attacks on critical cloud-hosted services, resource adaptation schemes adopted by the cloud service providers (CSPs) need to be intelligent. Specifically, they need to be adaptable to ... ...

Abstract	With the increased frequency and intensity of denial-of-service (DoS) attacks on critical cloud-hosted services, resource adaptation schemes adopted by the cloud service providers (CSPs) need to be intelligent. Specifically, they need to be adaptable to attack behavior and be dynamic to curb resource over-utilization. The concept of moving target defense (MTD) has recently emerged as an effective and agile defense mechanism against DoS attacks that particularly target cloud-hosted applications. However, the existing surveys that seek to explore this space either focus more on MTD for generic cyberattack mitigation or on DoS attack defense on cloud systems. In this survey, we particularly provide an in-depth analysis on how MTD can help recover critical cloud assets in the face of DoS attacks and how emerging programmable technologies such as software-defined networking (SDN) can be leveraged to achieve that goal. Unlike existing surveys, we categorize DoS attacks on cloud platforms based on their working mechanism. We also discuss the non-MTD-based DoS defense strategies for both cloud and non-cloud infrastructures in order to highlight the pros and cons of MTD-based strategies. We introduce MTD working mechanisms and present how existing research is envisioning MTD’s application in mitigating DoS attacks, both with and without SDN. We also take an in-depth look at the testbed implementations and resilience and performance evaluations of MTD approaches. Finally, we articulate the existing challenges in MTD for DoS mitigation in cloud systems and how these challenges are shaping the future research in this domain.
Keywords	Technology (General) ; T1-995 ; Science (General) ; Q1-390
Subject code	303
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Influence of temperature and pressure in vacuum drying of Crinum latifolium flower bulb

Minh, Nguyen Phuoc

Research on crops. 2022 June, v. 23, no. 2

2022

Abstract: Crinum latifolium flower bulb has excellent medicinal value due to its phytochemical components, especially alkaloids. These alkaloids have attracted considerable attention due to their interesting pharmacological properties. Vacuum drying is an ... ...

Abstract	Crinum latifolium flower bulb has excellent medicinal value due to its phytochemical components, especially alkaloids. These alkaloids have attracted considerable attention due to their interesting pharmacological properties. Vacuum drying is an important process for dehydration of highly heat-sensitive materials. This research was conducted at STNanotech laboratory, Soc Trang province, Vietnam in 2021 to evaluate the influence of drying temperature and vacuum pressure to the phenolic composition and the antioxidant capacity of Crinum latifolium flower bulb. Raw flower bulbs were dried under vacuum dryer at different temperature (40ᵒC, 45ᵒC, 50ᵒC, 55ᵒC, 60ᵒC) and pressure (−0.2, -0.4, -0.6, -0.8, -1.0 bar) for 4 hours and were evaluated for total phenolic content (TPC), total flavonoid content (TFC), diphenyl picrylhydrazyl content (DPPH), 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) content (ABTS). Results showed that vacuum drying at 40ᵒC at a vacuum pressure -0.8 bar would retain retained the highest total phenolic content (244 mg gae/100 g), flavonoid content (123 mg QE/100 g), DPPH free radical scavenging (109 \|ug/mL), ABTS radical scavenging activity (1.96 mM TE/g) of the dried flower bulb. From vacuum dehydration, the fresh Crinum latifolium could be converted into one kind of herbal tea with numerous health benefits.
Keywords	Crinum ; antioxidant activity ; biphenyl ; bulbs ; flavonoids ; flowers ; free radicals ; herbal tea ; research ; thermosensitivity ; Vietnam
Language	English
Dates of publication	2022-06
Size	p. 413-417.
Publishing place	Gaurav Publications.
Document type	Article
ISSN	2348-7542
DOI	10.31830/2348-7542.2022.056
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: System for recognising and monitoring the technical condition of construction machines

Minh Nguyen Trong / Zorin V.A

E3S Web of Conferences, Vol 389, p

2023 Volume 01054

Abstract: Assessing and predicting machine reliability and failure risks is an essential requirement of international standards for machine safety. The existing methods for determining reliability indicators and risk assessment are based on statistical information ...

Abstract	Assessing and predicting machine reliability and failure risks is an essential requirement of international standards for machine safety. The existing methods for determining reliability indicators and risk assessment are based on statistical information about failures and faults that occur during machine operation. Collecting, accumulation and processing of statistical data about failures of machines by traditional methods does not provide the necessary efficiency and reliability of the received information. In this connection forecasting of reliability, estimation, and risk management in production and operation of machines with necessary reliability is not a simple task. Modern diagnostic systems offer unlimited possibilities for the timely acquisition and transmission of information concerning the technical condition of machines, which can be used for the solution of problems. Depending on the structure and location of the transmission, storage and processing of the information, a distinction is made between stationary or remote diagnostics systems. With the modern development of communication and data transmission, remote systems are improved versions of stationary diagnostic systems. In the article the questions of formation of a recognition system and monitoring of a technical condition of building machines by means of the diagnostic information are considered. The main purpose of the development and implementation of the system is to ensure the reliability and safety of operation of construction machines. In order to solve this problem, it is necessary to recognize and promptly prevent the occurrence of failure, which requires the allocation of a special class of intermediate states, called pre-emergency. The results of the implementation of the recognition and monitoring system of construction machines with the help of diagnostic information are presented.
Keywords	Environmental sciences ; GE1-350
Subject code	600
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Testusterol, a new sterol of the sponge species

Vu Luu, Phuong / Minh Nguyen, Hien / Minh Phan, Phuc / Duy Vo, An / Ton-Nu, Huong Lien

Natural product research

2024 , Page(s) 1–9

Abstract: A new sterol, named testusterol ( ...

Abstract	A new sterol, named testusterol (
Language	English
Publishing date	2024-04-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2024.2340757
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Article ; Online: Proposal for a new customization process for a data-based water quality index using a random forest approach.

Lee, Hansaem / Park, Seonyoung / V-Minh Nguyen, Hang / Shin, Hyun-Sang

Environmental pollution (Barking, Essex : 1987)

2023 Volume 323, Page(s) 121222

Abstract: As the water quality index (WQI) represents water quality, it is crucial to customize the WQI for a specific purpose. In this study, to better represent water quality data using WQI, a random forest (RF) approach was used to derive the parameter weight ... ...

Abstract	As the water quality index (WQI) represents water quality, it is crucial to customize the WQI for a specific purpose. In this study, to better represent water quality data using WQI, a random forest (RF) approach was used to derive the parameter weight and calculate the WQI according to the watershed and its use. Eight parameters (water temperature, dissolved oxygen, pH, electrical conductivity, suspended solids, total nitrogen, total phosphorus, and total organic carbon) were evaluated using a total of 220,103 data points collected from 900 monitoring sites throughout South Korea between 2011 and 2020. The estimation of parameter weights, key elements in developing the WQI model, was performed through the variable importance estimation method that can be derived from the RF model. The parameter weights were derived based on various spatiotemporal datasets, and it was confirmed that the spatiotemporal differences in weights according to data characteristics represented the regional and seasonal water quality characteristics. Consequently, a customized WQI representing water quality characteristics could be calculated using data-based weights, and it is expected that a data-based customized WQI could be developed to better match the previous WQI to the purpose and target source.
MeSH term(s)	Water Quality ; Environmental Monitoring/methods ; Random Forest ; Oxygen/analysis ; Phosphorus/analysis ; Water Pollutants, Chemical/analysis ; Rivers
Chemical Substances	Oxygen (S88TT14065) ; Phosphorus (27YLU75U4W) ; Water Pollutants, Chemical
Language	English
Publishing date	2023-02-06
Publishing country	England
Document type	Journal Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2023.121222
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Article: Microencapsulation and spray drying on physicochemical and phytochemical attributes of lakum (Cayratia trifolia) dried powder

Minh, Nguyen Phuoc

Research on crops. 2021 June, v. 22, no. 2

2021

Abstract: Lakum (Cayratia trifolia) berry is underutilized herbaceous climber containing a huge content of anthocyanin greatly contributing to health benefits. In order to increase its commercial value via deep-processing, this research was conducted at Soc Trang ... ...

Abstract	Lakum (Cayratia trifolia) berry is underutilized herbaceous climber containing a huge content of anthocyanin greatly contributing to health benefits. In order to increase its commercial value via deep-processing, this research was conducted at Soc Trang Nanotech laboratory in 2020 to evaluate the microencapsulation of anthocyanin from lakum extract by spray drying under various wall materials (whey protein, soy protein isolate, maltodextrin, cyclodextrin, gum Arabic, xanthan gum, inulin), inlet/outlet air drying temperatures (160/50, 165/55, 170/60, 175/65, 180/70, 185/75, 190/80, °C/°C). The anthocyanin retention, total phenolic content, hygroscopicity and wettability was verified. Results showed that gum Arabic as wall material with inlet/outlet temperature 175/65 °C/°C induced the most desirable attributes of lakum dried powder to achieve the highest anthocyanin retention (74.19%), total phenolic content (197.81 mg GAE/ 100 g), hygroscopicity (12.04%), wettability (0.74 minutes). Meanwhile the lowest anthocyanin retention (57.42%) and total phenolic content (134.20 mg GAE/ 100 g); the highest hygroscopicity (15.78%) and wettability (3.24 minutes) was noticed at whey protein. These findings proved the impact of wall material and inlet/outlet air drying temperature during microencapsulation under optimised spray drying circumstance.
Keywords	Cayratia trifolia ; air ; anthocyanins ; cyclodextrins ; gum arabic ; hygroscopicity ; inulin ; maltodextrins ; microencapsulation ; research ; soy protein isolate ; wettability ; whey protein ; xanthan gum
Language	English
Dates of publication	2021-06
Size	p. 451-458.
Publishing place	Gaurav Publications
Document type	Article
ISSN	2348-7542
DOI	10.31830/2348-7542.2021.090
Database	NAL-Catalogue (AGRICOLA)

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Article: Tragacanth gum coating on postharvest quality of mabolo (Diospyros philippensis) fruit

Minh, Nguyen Phuoc

Research on crops. 2021 June, v. 22, no. 2

2021

Abstract: The shelf life and quality of Mabolo an ethnobotanical fruit rich in aroma with different volatile compounds is yet to be tested using natural edible coating using Tragacanth gum a versatile hydrocolloid widely applied in pharmaceutical and food industry. ...

Abstract	The shelf life and quality of Mabolo an ethnobotanical fruit rich in aroma with different volatile compounds is yet to be tested using natural edible coating using Tragacanth gum a versatile hydrocolloid widely applied in pharmaceutical and food industry. This intervention can possibly increase the commercial interest of the fruit. In order to evaluate the possibility of Tragacanth gum in preserving Diospyros philippensis fruit, a study was conducted at Soc Trang Nanotech laboratory in 2020 using different concentrations (0-2.5% w/v) of Tragacanth gum on the firmness, weight loss, ascorbic acid content, total plate count and overall acceptability of the coated fruit kept under ambient temperature for 8 days of storage. Results showed that 2.0% of Tragacanth gum would be appropriate to preserve the highest firmness (4.02 N), ascorbic acid content (28.97 mg/ 100g), sensory score (8.17); the lowest percentage of weight loss (0.86%), aerobic microbial load (1.47 log cfu/g). Tragacanth gum will be an excellent candidate for commercial development.
Keywords	Diospyros ; ambient temperature ; ascorbic acid ; ethnobotany ; firmness ; food industry ; fruits ; gum tragacanth ; hydrocolloids ; microbial load ; odors ; plate count ; research ; shelf life ; weight loss
Language	English
Dates of publication	2021-06
Size	p. 445-450.
Publishing place	Gaurav Publications
Document type	Article
ISSN	2348-7542
DOI	10.31830/2348-7542.2021.089
Database	NAL-Catalogue (AGRICOLA)

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