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  1. Article ; Online: Muscle in vein conduits: our experience.

    Minini, Andrea / Megaro, Almerico

    Acta bio-medica : Atenei Parmensis

    2021  Volume 92, Issue S1, Page(s) e2021163

    Abstract: Muscle in vein (MIV ) conduits have gradually been employed in the last 20 years as a valuable technique in bridging peripheral nerve gaps after nerve lesions who cannot undergo a direct tension-free coaptation. The advantages of this procedure comparing ...

    Abstract Muscle in vein (MIV ) conduits have gradually been employed in the last 20 years as a valuable technique in bridging peripheral nerve gaps after nerve lesions who cannot undergo a direct tension-free coaptation. The advantages of this procedure comparing to the actual benchmark (autograft) is the sparing of the donor site, and the huge availability of both components (i.e. muscle and veins). Here we present a case serie of four MIV performed at our hospital from 2018 to 2019. The results we obtained in our experi-ence confirmed its effectiveness both in nerve regeneration (as sensibility recovery) and in neuropathic pain eradication. Our positive outcomes encourage its use in selected cases of residual nerve gaps up to 30 mm.
    MeSH term(s) Humans ; Muscles ; Nerve Regeneration ; Peripheral Nerve Injuries ; Peripheral Nerves ; Veins/diagnostic imaging ; Veins/surgery
    Language English
    Publishing date 2021-04-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v92iS1.9202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How to monitor the brain in COVID-19 patients?

    Peluso, Lorenzo / Minini, Andrea / Taccone, Fabio Silvio

    Intensive & critical care nursing

    2021  Volume 63, Page(s) 103011

    MeSH term(s) Adult ; Brain Diseases/diagnosis ; Brain Diseases/physiopathology ; COVID-19/diagnosis ; COVID-19/nursing ; COVID-19/physiopathology ; Critical Care Nursing/standards ; Female ; Humans ; Male ; Middle Aged ; Monitoring, Physiologic/standards ; Practice Guidelines as Topic ; SARS-CoV-2
    Language English
    Publishing date 2021-01-05
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2020.103011
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  3. Article: Predicting fluid responsiveness with the passive leg raising test: don't be fooled by intra-abdominal hypertension!

    Minini, Andrea / Abraham, Paul / Malbrain, Manu L N G

    Annals of translational medicine

    2020  Volume 8, Issue 12, Page(s) 799

    Language English
    Publishing date 2020-07-10
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2019.12.14
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  4. Article ; Online: Transpulmonary thermodilution during extracorporeal organ support (ECOS): is it worth it?A brief commentary on the effects of the extracorporeal circuit on TPTD-derived parameters.

    Minini, Andrea / Raes, Matthias / Taccone, Fabio S / Malbrain, Manu L N G

    Journal of clinical monitoring and computing

    2021  Volume 35, Issue 4, Page(s) 681–687

    MeSH term(s) Cardiac Output ; Humans ; Thermodilution
    Language English
    Publishing date 2021-04-23
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 1418733-4
    ISSN 1573-2614 ; 1387-1307 ; 0748-1977
    ISSN (online) 1573-2614
    ISSN 1387-1307 ; 0748-1977
    DOI 10.1007/s10877-021-00699-9
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    Zs.A 2054: Show issues Location:
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  5. Article: Sensitive peripheral nerve repair during COVID-19 emergency: does the outpatient surgical setting work as well as the operating theater?

    Garutti, Leonardo / Tamborini, Federico / Fagetti, Alessandro / Baroni, Tommaso / Bascialla, Elisa / Minini, Andrea / Cherubino, Mario / Valdatta, Luigi

    European journal of plastic surgery

    2023  , Page(s) 1–5

    Abstract: Background: Nerve injuries are a common occurrence among hand injuries, which at the time of the COVID-19 emergency, did not appear to have reduced their incidence. The treatment of these injuries is urgent, but the pandemic has led to a reduction in ... ...

    Abstract Background: Nerve injuries are a common occurrence among hand injuries, which at the time of the COVID-19 emergency, did not appear to have reduced their incidence. The treatment of these injuries is urgent, but the pandemic has led to a reduction in the availability of resources and a consequent reorganization of activities. Principles about Wide-Awake Local Anesthesia No Tourniquet (WALANT) in hand surgery expressed by LaLonde helped hand surgeons to adapt to this new condition by demonstrating a possible outpatient pathway for the treatment of hand traumatic conditions. In the present study, we bring our experience in nerve repair at time of COVID-19 emergency.
    Methods: We retrospectively enrolled in this study all patients surgically treated for a peripheral nerve injury (PNI) during the COVID-19 emergency period from March 2020 to March 2022. Demographical, anamnestic, surgical, and postoperative data were recorded and analyzed. Persisting Tinel was set as the primary outcome, while hypoesthesia and other complications as secondary outcomes.
    Results: Thirty-six patients have been enrolled. Despite some difference in group homogeneity in term of hypertension and multi-digital involvement, we registered no difference in term of outcomes (
    Conclusions: Nerve repair on an outpatient facility is technically feasible and was found in this study to be safe and effective. Compared to hospitalization, the outpatient setting has a more "agile" organization and lower costs, making it preferable in selected cases.Level of evidence: Level IV, Therapeutic.
    Language English
    Publishing date 2023-06-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 632906-8
    ISSN 1435-0130 ; 0930-343X
    ISSN (online) 1435-0130
    ISSN 0930-343X
    DOI 10.1007/s00238-023-02085-x
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  6. Article ; Online: The Role of Brain Tissue Oxygenation Monitoring in the Management of Subarachnoid Hemorrhage: A Scoping Review.

    Gouvea Bogossian, Elisa / Battaglini, Denise / Fratino, Sara / Minini, Andrea / Gianni, Giuseppina / Fiore, Marco / Robba, Chiara / Taccone, Fabio Silvio

    Neurocritical care

    2023  Volume 39, Issue 1, Page(s) 229–240

    Abstract: Monitoring of brain tissue oxygenation ( ... ...

    Abstract Monitoring of brain tissue oxygenation (PbtO
    MeSH term(s) Humans ; Subarachnoid Hemorrhage/diagnosis ; Subarachnoid Hemorrhage/therapy ; Subarachnoid Hemorrhage/complications ; Brain ; Brain Injuries, Traumatic ; Brain Ischemia/diagnosis ; Brain Ischemia/therapy ; Brain Ischemia/complications ; Hypoxia, Brain ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2381896-7
    ISSN 1556-0961 ; 1541-6933
    ISSN (online) 1556-0961
    ISSN 1541-6933
    DOI 10.1007/s12028-023-01680-x
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    Zs.A 6538: Show issues Location:
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  7. Article: Chronic exertional compartment syndrome of the forearm: a systematic review.

    Smeraglia, Francesco / Tamborini, Federico / Garutti, Leonardo / Minini, Andrea / Basso, Morena A / Cherubino, Mario

    EFORT open reviews

    2021  Volume 6, Issue 2, Page(s) 101–106

    Abstract: The aim of this systematic review is to understand which surgical procedure provides better results in terms of pain relief and function in the treatment of chronic exertional compartment syndrome (CECS) of the forearm.We searched Medline (PubMed), Web ... ...

    Abstract The aim of this systematic review is to understand which surgical procedure provides better results in terms of pain relief and function in the treatment of chronic exertional compartment syndrome (CECS) of the forearm.We searched Medline (PubMed), Web of Science, Embase and Scopus databases on 8 July 2020. Twelve studies were included in this review.We assessed the quality of the studies using the Coleman Methodological Score.Data on demographic features, operative readings, diagnostic methods, follow-up periods, type and rates of complications, survivorship of the procedure, return to sport activity, and outcome measures were recorded.In conclusion, compared to the other techniques, endoscopic fasciotomy delivers similar success rates and lower incidence of complications. Cite this article:
    Language English
    Publishing date 2021-02-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2844421-8
    ISSN 2058-5241 ; 2058-5241 ; 2396-7544
    ISSN (online) 2058-5241
    ISSN 2058-5241 ; 2396-7544
    DOI 10.1302/2058-5241.6.200107
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  8. Article: Which Target Temperature for Post-Anoxic Brain Injury? A Systematic Review from "Real Life" Studies.

    Minini, Andrea / Annoni, Filippo / Peluso, Lorenzo / Bogossian, Elisa Gouvêa / Creteur, Jacques / Taccone, Fabio Silvio

    Brain sciences

    2021  Volume 11, Issue 2

    Abstract: There is a persistent debate on the optimal target temperature to use during cooling procedures in cardiac arrest survivors. A large randomized clinical trial (RCT) including more than 900 patients showed that targeted temperature management (TTM) at 33 ° ...

    Abstract There is a persistent debate on the optimal target temperature to use during cooling procedures in cardiac arrest survivors. A large randomized clinical trial (RCT) including more than 900 patients showed that targeted temperature management (TTM) at 33 °C had similar mortality and unfavorable neurological outcome (UO) rates as TTM at 36 °C in out-of-hospital cardiac arrest patients with any initial rhythm. Since then, several observational studies have been published on the effects of changes in target temperature (i.e., from 33 to 36 °C) on patients' outcome. We performed a systematic literature search from 1 January 2014 to 4 December 2020 and identified nine retrospective studies (very low levels of certainty; high risk of bias), including 3799 patients, that evaluated TTM at 33 °C vs. TTM at 36 °C on the occurrence of UO (n = seven studies) and mortality (n = nine studies). TTM at 33 °C was associated with a lower risk of UO when studies assessing neurological outcome with the Cerebral Performance Categories were analyzed (OR 0.80 [95% CIs 0.65-0.99];
    Language English
    Publishing date 2021-02-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci11020186
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  9. Article ; Online: Ventilator-associated bacterial pneumonia in coronavirus 2019 disease, a retrospective monocentric cohort study.

    Moretti, Marco / Van Laethem, Johan / Minini, Andrea / Pierard, Denis / Malbrain, Manu L N G

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2021  Volume 27, Issue 6, Page(s) 826–833

    Abstract: Introduction: Severe coronavirus 2019 disease (CoViD-19) may lead to respiratory failure and mechanical ventilation. Therefore, ventilator associated pneumonia (VAP) may complicate the course of the disease. The aim of the current article was to ... ...

    Abstract Introduction: Severe coronavirus 2019 disease (CoViD-19) may lead to respiratory failure and mechanical ventilation. Therefore, ventilator associated pneumonia (VAP) may complicate the course of the disease. The aim of the current article was to investigate possible predictive factors for bacterial VAP on a retrospective manner, in a cohort of mechanically ventilated CoViD-19 patients. Additionally, determinant factors of lethality were analyzed.
    Methods: Medical records of patients hospitalized in the intensive care units (ICU) at the university hospital UZ Brussel during the epidemic were reviewed. VAP was defined following the National Healthcare Safety Network 2017 criteria. Univariate and multivariate logistic regressions analyses were performed.
    Results: Among the 39 patients included in the study, 54% were diagnosed with bacterial VAP. Case fatality rate was 44%, but 59% of the deceased patients had a do-not-resuscitate status. Multivariate logistic regression for prediction of VAP showed significant differences in duration of ICU hospitalization and in minimal lung compliance. Additional analyses were performed on CoViD-19 patients who were affected by bacterial respiratory superinfection. The responsible pathogens correspond to the commonly found bacteria in VAP. However, 71% of the isolated germs were multi-drug resistant and bacteraemia was reported in 38%. Multivariate analyses for prediction of lethality found significant difference in SOFA score.
    Conclusions: Mechanically ventilated CoViD-19 patients might frequently develop VAP. Longer ICU hospitalization was associated with pulmonary superinfection in the current cohort. Moreover, decreased minimal lung compliance was correlated to VAP and higher SOFA score at VAP diagnosis was associated with lethality.
    MeSH term(s) Aged ; COVID-19/epidemiology ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Pneumonia, Bacterial/epidemiology ; Pneumonia, Bacterial/mortality ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/microbiology ; Pneumonia, Ventilator-Associated/mortality ; Respiration, Artificial ; Retrospective Studies ; Ventilators, Mechanical
    Language English
    Publishing date 2021-01-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2021.01.011
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    Zs.A 5236: Show issues Location:
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  10. Article ; Online: Association of Acute Trapeziometacarpal Joint Dislocation and Trapezium Fracture in a 14-Year-Old Boy: A Case Report.

    Minini, Andrea / Fagetti, Alessandro / Tamborini, Federico / Di Giovanna, Danilo / Salvi, Andrea G / Maffeis, Jacopo / Sibona, Federico / Cherubino, Mario

    Hand (New York, N.Y.)

    2022  Volume 18, Issue 1, Page(s) NP10–NP14

    Abstract: Fracture-dislocation of the trapeziometacarpal (TM) joint in adolescent patients is a rare injury, with only 3 cases reported in literature to our knowledge. Its low incidence, together with the complexity of the anatomy and biomechanics of TM joint, may ...

    Abstract Fracture-dislocation of the trapeziometacarpal (TM) joint in adolescent patients is a rare injury, with only 3 cases reported in literature to our knowledge. Its low incidence, together with the complexity of the anatomy and biomechanics of TM joint, may represent a challenge for surgeons in choosing the best treating option. Here, we report a case of a TM fracture dislocation in a 14-year-old boy treated with percutaneous Kirschner wire pinning. The results we obtained endorsed our choice in patients for whom closed reduction is achievable.
    MeSH term(s) Male ; Humans ; Adolescent ; Fractures, Bone/diagnostic imaging ; Fractures, Bone/surgery ; Wrist Injuries ; Joint Dislocations/diagnostic imaging ; Joint Dislocations/surgery ; Hand Injuries ; Bone Wires ; Fracture Dislocation/diagnostic imaging ; Fracture Dislocation/surgery
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2277325-3
    ISSN 1558-9455 ; 1558-9447
    ISSN (online) 1558-9455
    ISSN 1558-9447
    DOI 10.1177/15589447221092121
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