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  1. Article ; Online: Ultrasound for management of left ventricular assist device driveline infections: A single-center experience.

    Lissandrin, Raffaella / Sangani, Aurelia / Pesare, Rebecca / Minucci, Rita / Pisani, Giulia Pinuccia / Gazzoli, Fabrizio / Pelenghi, Stefano / Bruno, Raffaele / Seminari, Elena

    Transplant infectious disease : an official journal of the Transplantation Society

    2023  Volume 26, Issue 1, Page(s) e14178

    MeSH term(s) Humans ; Heart-Assist Devices/adverse effects ; Heart Failure/therapy ; Ultrasonography ; Prosthesis-Related Infections/diagnostic imaging
    Language English
    Publishing date 2023-10-23
    Publishing country Denmark
    Document type Letter
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.14178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reduction of BSI associated mortality after a sepsis project implementation in the ER of a tertiary referral hospital.

    Seminari, Elena / Colaneri, Marta / Corbella, Marta / De Silvestri, Annalisa / Muzzi, Alba / Perlini, Stefano / Martino, Ilaria Francesca / Marvulli, Lea Nadia / Arcuri, Alessia / Maffezzoni, Marcello / Minucci, Rita / Bono, Enrica / Cambieri, Patrizia / Marone, Piero / Bruno, Raffaele

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 5142

    Abstract: The emergency room (ER) is the first gateway for patients with sepsis to inpatient units, and identifying best practices and benchmarks to be applied in this setting might crucially result in better patient's outcomes. In this study, we want to evaluate ... ...

    Abstract The emergency room (ER) is the first gateway for patients with sepsis to inpatient units, and identifying best practices and benchmarks to be applied in this setting might crucially result in better patient's outcomes. In this study, we want to evaluate the results in terms of decreased the in-hospital mortality of patients with sepsis of a Sepsis Project developed in the ER. All patients admitted to the ER of our Hospital from the 1st January, 2016 to the 31stJuly 2019 with suspect of sepsis (MEWS score ≥ of 3) and positive blood culture upon ER admission were included in this retrospective observational study. The study comprises of two periods: Period A: From the 1st Jan 2016 to the 31st Dec 2017, before the implementation of the Sepsis project. Period B: From the 1st Jan 2018 to the 31stJul 2019, after the implementation of the Sepsis project. To analyze the difference in mortality between the two periods, a univariate and multivariate logistic regression was used. The risk of in-hospital mortality was expressed as an odds ratio (OR) and a 95% confidence interval (95% CI). Overall, 722 patients admitted in ER had positive BC on admissions, 408 in period A and 314 in period B. In-hospital mortality was 18.9% in period A and 12.7% in period B (p = 0.03). At multivariable analysis, mortality was still reduced in period B compared to period A (OR 0.64, 95% CI 0.41-0.98; p = 0.045). Having an infection due to GP bacteria or polymicrobial was associated with an increased risk of death, as it was having a neoplasm or diabetes. A marked reduction in in-hospital mortality of patients with documented BSI associated with signs or symptoms of sepsis after the implementation of a sepsis project based on the application of sepsis bundles in the ER.
    MeSH term(s) Humans ; Tertiary Care Centers ; Hospitalization ; Sepsis ; Retrospective Studies ; Hospital Mortality ; Emergency Service, Hospital
    Language English
    Publishing date 2023-03-29
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-31219-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of Pneumococcal Urinary Antigen Testing in COVID-19 Patients: Outcomes from the San Matteo COVID-19 Registry (SMACORE).

    Valsecchi, Pietro / Colaneri, Marta / Zuccaro, Valentina / Asperges, Erika / Costanzo, Filippo / Mariani, Bianca / Roda, Silvia / Minucci, Rita / Bertuccio, Francesco / Fraolini, Elia / Bosio, Matteo / Tirelli, Claudio / Oggionni, Tiberio / Corsico, Angelo / Bruno, Raffaele

    Journal of personalized medicine

    2021  Volume 11, Issue 8

    Abstract: Despite low rates of bacterial co-infections, most COVID-19 patients receive antibiotic therapy. We hypothesized that patients with positive pneumococcal urinary antigens (PUAs) would benefit from antibiotic therapy in terms of clinical outcomes (death, ... ...

    Abstract Despite low rates of bacterial co-infections, most COVID-19 patients receive antibiotic therapy. We hypothesized that patients with positive pneumococcal urinary antigens (PUAs) would benefit from antibiotic therapy in terms of clinical outcomes (death, ICU admission, and length of stay). The San Matteo COVID-19 Registry (SMACORE) prospectively enrolls patients admitted for COVID-19 pneumonia at IRCCS Policlinico San Matteo, Pavia. We retrospectively extracted the data of patients tested for PUA from October to December 2020. Demographic, clinical, and laboratory data were recorded. Of 469 patients, 42 tested positive for PUA (8.95%), while 427 (91.05%) tested negative. A positive PUA result had no significant impact on death (HR 0.53 CI [0.22-1.28]
    Language English
    Publishing date 2021-07-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm11080762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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