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  1. Article ; Online: Global Agri-Food Sector: Challenges and Opportunities in COVID-19 Pandemic.

    Hamid, Saima / Mir, Mohammad Yaseen

    Frontiers in sociology

    2021  Volume 6, Page(s) 647337

    Abstract: COVID-19 pandemic has been catastrophic for almost everything including the global economy. Among many sectors, the food and the agriculture sector was the worst hit following the immediate lockdown and market shutdowns. Though some stability was ... ...

    Abstract COVID-19 pandemic has been catastrophic for almost everything including the global economy. Among many sectors, the food and the agriculture sector was the worst hit following the immediate lockdown and market shutdowns. Though some stability was prevalent from supply side till date, however, the severe restrictions put in place to curb the spread of pandemic have endangered the supply of agricultural and food articles contemporaneously across borders and from field to fork. While the income decline due to price falland supplies chain disruptions due to pandemic have escalated the food shortages in several of developing and developed countries. Nevertheless the global demand for food items has remained more or less unchanged owing to their inelastic demand. Even within the global level, the scenario of food security and supply chain stability has been substantially deplorable for emerging and less developing countries due to their lack of insulation to the global shocks or pandemics. Notably, the technological backwardness, excessive know-how dependence and denied accessibility on several grounds lead to poverty and food hunger in these countries. At the policy level, a holistic approach specifically targeted towards the developing and less developed economies is highly warranted to ensure an appreciable progress towards the minimisation of sensitivity with regard to agriculture and food security. Apart from the measures to insulate them from global shocks, additional steps need to be taken to alleviate their technological backwardness and denied accessibility on certain socio-cultural norms.
    Language English
    Publishing date 2021-07-12
    Document type Journal Article ; Review
    ISSN 2297-7775
    ISSN (online) 2297-7775
    DOI 10.3389/fsoc.2021.647337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Novel coronavirus disease (COVID-19): a pandemic (epidemiology, pathogenesis and potential therapeutics).

    Hamid, Saima / Mir, Mohammad Yaseen / Rohela, Gulab Khan

    New microbes and new infections

    2020  Volume 35, Page(s) 100679

    Abstract: The coronavirus disease (COVID-19) is highly pathogenic viral infection caused by SARS-CoV-2. Currently, COVID-19 has caused global health concern. It is assumed that COVID-19 has zoonotic origin based on the large number of infected people who were ... ...

    Abstract The coronavirus disease (COVID-19) is highly pathogenic viral infection caused by SARS-CoV-2. Currently, COVID-19 has caused global health concern. It is assumed that COVID-19 has zoonotic origin based on the large number of infected people who were exposed to the wet market in Wuhan City, China. The phylogenetic analysis has revealed that SARS-CoV-2 has significant sequence similarity with severe acute respiratory syndrome-like (SARS-like) bat viruses, thus bats could be primary possible reservoir. The intermediate host and there subsequent transfer is not known yet, although human to human transfer is widely confirmed. The transmission of COVID-19 infection from one person to another resulted in the isolation of patients who were subsequently given a variety of treatments. To monitor the current outbreak, robust steps have been taken around the globe to reduce the transmission of COVID-19 infection particularly banning international and domestic flights, inducting lockdowns in vulnerable areas, social distancing etc. No clinically approved antiviral drug or vaccine against COVID-19 is reported yet. However, in clinical trials, few broad-spectrum antiviral drugs were evaluated against COVID-19 infection which resulted in clinical recovery. In this article emergence and pathogenicity of COVID-19 infection along with potential therapeutic strategies are analyzed to combat the COVID-19 pandemic.
    Keywords covid19
    Language English
    Publishing date 2020-04-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2750179-6
    ISSN 2052-2975
    ISSN 2052-2975
    DOI 10.1016/j.nmni.2020.100679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Novel coronavirus disease (COVID-19): a pandemic (epidemiology, pathogenesis and potential therapeutics)

    Hamid, Saima / Mir, Mohammad Yaseen / Rohela, Gulab Khan

    New Microbes New Infect.

    Abstract: The coronavirus disease (COVID-19) is highly pathogenic viral infection caused by SARS-CoV-2. Currently, COVID-19 has caused global health concern. It is assumed that COVID-19 has zoonotic origin based on the large number of infected people who were ... ...

    Abstract The coronavirus disease (COVID-19) is highly pathogenic viral infection caused by SARS-CoV-2. Currently, COVID-19 has caused global health concern. It is assumed that COVID-19 has zoonotic origin based on the large number of infected people who were exposed to the wet market in Wuhan City, China. The phylogenetic analysis has revealed that SARS-CoV-2 has significant sequence similarity with severe acute respiratory syndrome-like (SARS-like) bat viruses, thus bats could be primary possible reservoir. The intermediate host and there subsequent transfer is not known yet, although human to human transfer is widely confirmed. The transmission of COVID-19 infection from one person to another resulted in the isolation of patients who were subsequently given a variety of treatments. To monitor the current outbreak, robust steps have been taken around the globe to reduce the transmission of COVID-19 infection particularly banning international and domestic flights, inducting lockdowns in vulnerable areas, social distancing etc. No clinically approved antiviral drug or vaccine against COVID-19 is reported yet. However, in clinical trials, few broad-spectrum antiviral drugs were evaluated against COVID-19 infection which resulted in clinical recovery. In this article emergence and pathogenicity of COVID-19 infection along with potential therapeutic strategies are analyzed to combat the COVID-19 pandemic.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #87551
    Database COVID19

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  4. Article ; Online: Novel coronavirus disease (COVID-19)

    Hamid, Saima / Mir, Mohammad Yaseen / Rohela, Gulab Khan

    New Microbes and New Infections

    a pandemic (epidemiology, pathogenesis and potential therapeutics)

    2020  Volume 35, Page(s) 100679

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2750179-6
    ISSN 2052-2975
    ISSN 2052-2975
    DOI 10.1016/j.nmni.2020.100679
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Sneak peek of Hypericum perforatum L.: phytochemistry, phytochemical efficacy and biotechnological interventions

    Mir, Mohammad Yaseen / Hamid, Saima / Hassan, Qazi P / Kamili, Azra N

    Journal of plant biochemistry and biotechnology. 2019 Dec., v. 28, no. 4

    2019  

    Abstract: The phytochemistry of Hypericum perforatum (St. John’s wort) has been elaborated extensively owing to its immense application in medicinal chemistry. Illustrated pharmacological activities like antidepressant, antiviral, and antibacterial effects ... ...

    Abstract The phytochemistry of Hypericum perforatum (St. John’s wort) has been elaborated extensively owing to its immense application in medicinal chemistry. Illustrated pharmacological activities like antidepressant, antiviral, and antibacterial effects demonstrated its substantiation for numerous of the conventional purposes reported for St John’s wort. St. John’s wort is herbal remedy extensively used in mild to moderate depression. Most of pharmacological activities were assigned to presence of photosensitive naphthodianthrone; hypericin and other allied flavonoid constituents. Escalating demands of hyperforin as antidepressant added more lure to H. perforatum L. The crude extracts of H. perforatum containing phloroglucinols were used for free radical scavenging and against DNA damage. To meet increasing demands of this drug, researchers need to tailor out the biosynthetic pathways to improve secondary metabolite. This necessitated advancement in biotechnological intervention to improve phytochemical potential of this growing herb. This review will brief out ecology, chemistry and phytochemical efficacy with respective phytoconstituents. Further, review will emphasize biotechnological interventions including both conventional and modern contrivances that have been implemented to augment the glory of this species.
    Keywords antibacterial properties ; antidepressants ; biochemical pathways ; chemical constituents of plants ; DNA damage ; ecology ; flavonoids ; free radical scavengers ; hyperforin ; hypericin ; Hypericum perforatum ; medicinal properties ; photosensitivity ; secondary metabolites ; traditional medicine
    Language English
    Dates of publication 2019-12
    Size p. 357-373.
    Publishing place Springer India
    Document type Article
    ZDB-ID 2206337-7
    ISSN 0974-1275 ; 0971-7811
    ISSN (online) 0974-1275
    ISSN 0971-7811
    DOI 10.1007/s13562-019-00490-7
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: In Vitro Regeneration and Free Radical Scavenging Assay of Hypericum perforatum L

    Mir, Mohammad Yaseen / Kamili, Azra N / Hassan, Qazi P / Rafi, Sabreena / Parray, Javid A / Jan, Sumira

    National Academy science letters. 2019 Apr., v. 42, no. 2

    2019  

    Abstract: The phytochemistry of Hypericum perforatum (St. John’s wort) has been elaborated extensively owing to its immense application in medicinal chemistry. Most of pharmacological activities were assigned to presence of photosensitive naphthodianthrone, ... ...

    Abstract The phytochemistry of Hypericum perforatum (St. John’s wort) has been elaborated extensively owing to its immense application in medicinal chemistry. Most of pharmacological activities were assigned to presence of photosensitive naphthodianthrone, hypericin and other allied flavonoid constituents. Escalating demands of hyperforin as antidepressant added more lure to Hypericum perforatum L. In the current study, efforts were made for quick propagation of the plant by in vitro culture using nodal explants. The nodal explants were cultured on agarized Murashige and Skoog (MS) medium supplemented with auxin and cytokinin. The highest number of shoots (50.5) per explant was found on media supplemented with 6-Benzylaminopurine (BAP) 7.5 μM and Indole-3-acetic acid (IAA) 2.0 μM. Our study showed 1.4 fold increment in shoot number viz –a-viz shoot morphogenesis from the nodal explants took about 24 days which is significantly shorter than earlier published reports. In the current study auxins Indole-3-butyric acid (IBA) and IAA were found to be equally important for root induction, whereas Napthalene acetic acid (NAA) was not required. The maximum root number (15.8) with 100% response was observed on MS + IBA (4.0 μM). Further, free radicals produced due to various environmental stresses and numerous metabolic processes ultimately lead to complete cell impairment. To combat this cellular damage organisms require dynamic defense systems. In addition to inherent defense machinery, we can supplement the defense systems of organisms with natural resources like herbs. In this regard, the free radical scavenging assay was also assessed. In our experiment line, best plant hormonal combination (I1 = MS + BAP 7.5 μM + IAA 2.0 μM) was selected on the basis of higher shootlet formation and their antioxidant activity was compared with in vitro control (I0 = MS) as well as with wild plants (W). I1 plant extracts have shown strong free radical scavenging activity with 1 fold increment as compared with wild and in vitro control.
    Keywords Hypericum perforatum ; acetic acid ; antidepressants ; antioxidant activity ; benzyladenine ; cytokinins ; explants ; flavonoids ; free radical scavengers ; free radicals ; herbs ; hyperforin ; hypericin ; indole acetic acid ; indole butyric acid ; medicinal properties ; morphogenesis ; naphthaleneacetic acid ; natural resources ; photosensitivity ; plant extracts ; rooting ; shoots ; wild plants
    Language English
    Dates of publication 2019-04
    Size p. 161-167.
    Publishing place Springer India
    Document type Article
    ZDB-ID 2677544-X
    ISSN 2250-1754 ; 0250-541X
    ISSN (online) 2250-1754
    ISSN 0250-541X
    DOI 10.1007/s40009-018-0699-x
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Manipulation of Plant Growth Regulators on Phytochemical Constituents and DNA Protection Potential of the Medicinal Plant

    Parray, Javid A / Kamili, Azra N / Jan, Sumira / Mir, Mohammad Yaseen / Shameem, Nowsheen / Ganai, Bashir A / Abd Allah, Elsayed Fathi / Hashem, Abeer / Alqarawi, Abdulaziz A

    BioMed research international

    2018  Volume 2018, Page(s) 6870139

    Abstract: ... Arnebia ... ...

    Abstract Arnebia benthamii
    MeSH term(s) Animals ; Antioxidants/chemistry ; Antioxidants/therapeutic use ; Boraginaceae/chemistry ; Cattle ; DNA/drug effects ; DNA Damage/drug effects ; Drug Compounding ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/pharmacology ; Humans ; Indoleacetic Acids/chemistry ; Indoleacetic Acids/pharmacology ; Phenylurea Compounds/chemistry ; Phenylurea Compounds/pharmacology ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Plant Growth Regulators/chemistry ; Plant Growth Regulators/pharmacology ; Plant Roots/chemistry ; Plant Shoots/chemistry ; Plants, Medicinal/chemistry ; Regeneration/drug effects ; Thiadiazoles/chemistry ; Thiadiazoles/pharmacology ; Tissue Culture Techniques
    Chemical Substances Antioxidants ; Free Radical Scavengers ; Indoleacetic Acids ; Phenylurea Compounds ; Phytochemicals ; Plant Growth Regulators ; Thiadiazoles ; thidiazuron (0091WH7STF) ; indoleacetic acid (6U1S09C61L) ; DNA (9007-49-2) ; calf thymus DNA (91080-16-9)
    Language English
    Publishing date 2018-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2018/6870139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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