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  1. Article ; Online: COVID-19

    Jorge Aquino-Matus / Misael Uribe / Norberto Chavez-Tapia

    Tropical Medicine and Infectious Disease, Vol 7, Iss 187, p

    Current Status in Gastrointestinal, Hepatic, and Pancreatic Diseases—A Concise Review

    2022  Volume 187

    Abstract: The gastrointestinal tract plays an important role in the pathogenesis of COVID-19. The angiotensin-converting enzyme 2 receptor and the transmembrane protease serine 2 receptor bind and activate SARS-CoV-2 and are present in high concentrations ... ...

    Abstract The gastrointestinal tract plays an important role in the pathogenesis of COVID-19. The angiotensin-converting enzyme 2 receptor and the transmembrane protease serine 2 receptor bind and activate SARS-CoV-2 and are present in high concentrations throughout the gastrointestinal tract. Most patients present with gastrointestinal symptoms and/or abnormal liver function tests, both of which have been associated with adverse outcomes. The mechanisms of liver damage are currently under investigation, but the damage is usually transient and nonsevere. Liver transplantation is the only definitive treatment for acute liver failure and end-stage liver disease, and unfortunately, because of the need for ventilators during the COVID-19 pandemic, most liver transplant programs have been suspended. Patients with gastrointestinal autoimmune diseases require close follow-up and may need modification in immunosuppression. Acute pancreatitis is a rare manifestation of COVID-19, but it must be considered in patients with abdominal pain. The gastrointestinal tract, including the liver and the pancreas, has an intimate relationship with COVID-19 that is currently under active investigation.
    Keywords COVID-19 ; SARS-CoV-2 ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Hepatology and the “new reality” ushered in by the COVID-19 pandemic

    Misael Uribe / Jorge Aquino-Matus

    Annals of Hepatology, Vol 19, Iss 5, Pp 449-

    2020  Volume 450

    Keywords Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Current approaches to hepatic encephalopathy

    Paulina Vidal-Cevallos / Norberto C. Chávez-Tapia / Misael Uribe

    Annals of Hepatology, Vol 27, Iss 6, Pp 100757- (2022)

    2022  

    Abstract: Hepatic encephalopathy (HE) is a brain dysfunction caused by liver insufficiency and/or portosystemic shunts. Between 30%–40% of patients with cirrhosis will present overt HE during their lifetime. While the pathophysiology of HE is not entirely ... ...

    Abstract Hepatic encephalopathy (HE) is a brain dysfunction caused by liver insufficiency and/or portosystemic shunts. Between 30%–40% of patients with cirrhosis will present overt HE during their lifetime. While the pathophysiology of HE is not entirely understood, three critical factors have been identified: hyperammonaemia, systemic inflammation and oxidative stress by glutaminase gene alterations. Minimal HE is defined by the presence of signs of cognitive abnormalities in a patient without asterixis or disorientation; it can only be diagnosed with neuropsychological or psychometric tests. The diagnosis of overt HE is based on clinical examination with clinical scales. Currently, only overt HE should be routinely treated. The aims of treatment in an acute episode should be to improve the mental status, identify and treat the precipitating factor, reduce duration and limit consequences. Treatment strategies are targeted at reducing ammonia production and/or increasing its elimination. Even though minimal HE has negative effects on the patient's quality of life and effects on prognosis, indications for treatment are still controversial. There are still many unanswered questions regarding the pathophysiology and management of HE. We should also endeavor to develop more accurate and objective diagnostic methods for overt HE that would permit early detection and help improve outcomes on quality of life and economic burden.
    Keywords Liver cirrhosis ; Classification ; Physiopathology ; Therapeutics ; Diagnosis ; Specialties of internal medicine ; RC581-951
    Subject code 610
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Clues to decipher the origin of severe acute hepatitis in children

    Misael Uribe / Arturo Panduro / Gisela DuPont / Nora A. Fierro

    Annals of Hepatology, Vol 27, Iss 4, Pp 100731- (2022)

    a new enigma during the COVID-19 pandemic

    2022  

    Keywords viral hepatitis ; liver disease and children ; Hepatitis E Virus ; Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The lack of guidelines and government policies for regulating nonprescription sale of antibiotics and its medical consequences

    Eva Juárez-Hernández / Misael Uribe

    Annals of Hepatology, Vol 18, Iss 6, Pp 783-

    2019  Volume 785

    Keywords Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2019-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Insulin resistance and Metabolic dysfunction-associated steatotic liver disease (MASLD)

    Andrea del Carmen Maldonado-Rojas / Julia María Zuarth-Vázquez / Misael Uribe / Varenka J Barbero-Becerra

    Annals of Hepatology, Vol 29, Iss 2, Pp 101182- (2024)

    Pathways of action of hypoglycemic agents

    1481  

    Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by overweight/obesity, and the presence of type 2 diabetes mellitus is the most important criterion. We propose an independent disease perspective without exclusion ... ...

    Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by overweight/obesity, and the presence of type 2 diabetes mellitus is the most important criterion. We propose an independent disease perspective without exclusion criteria and with less heterogeneity and greater impact because, according to the National Health and Nutrition Survey (ENSANUT), in Mexico, 25 % of adults over 60 years of age suffer from diabetes, and 96 % of those over 50 years of age have abdominal obesity. Due to the impact of insulin resistance in the pathophysiology of MASLD, which results in damage to hepatocytes, this work aims to provide an overview of the action pathways of hypoglycemic agents such as glucagon-like-1 receptor agonist and peroxisome proliferator-activated receptor-gamma agonists, whose importance lies in the fact that they are currently undergoing phase 2 studies, as well as dipeptidyl peptidase 4 inhibitors and sodium-glucose co-transporter type 2 inhibitors, which are undergoing phase 1 study trials.
    Keywords Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2024-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: COVID-19 vaccine-induced immune thrombotic thrombocytopenia

    Mateo Porres-Aguilar / Alejandro Lazo-Langner / Arturo Panduro / Misael Uribe

    Annals of Hepatology, Vol 23, Iss , Pp 100356- (2021)

    An emerging cause of splanchnic vein thrombosis

    2021  

    Keywords Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Systematic review and meta-analysis

    Luis Antonio Manzo-Francisco / Jorge Aquino-Matus / Dèsirée Vidaña-Pérez / Misael Uribe / Norberto Chavez-Tapia

    Annals of Hepatology, Vol 28, Iss 4, Pp 101107- (2023)

    Transient elastography compared to liver biopsy for staging of liver fibrosis in primary biliary cholangitis

    2023  

    Abstract: Introduction and Objectives: Primary biliary cholangitis (PBC) is an autoimmune liver disease, with 60% of patients being asymptomatic at diagnosis and 30% progressing rapidly into liver fibrosis. Liver biopsy is standard for staging fibrosis, but ... ...

    Abstract Introduction and Objectives: Primary biliary cholangitis (PBC) is an autoimmune liver disease, with 60% of patients being asymptomatic at diagnosis and 30% progressing rapidly into liver fibrosis. Liver biopsy is standard for staging fibrosis, but performance of non-invasive methods such as transient elastography (TE) have not been evaluated. We conducted a meta-analysis of articles up to May 2022 to evaluate the performance of TE compared with liver biopsy in adult patients with PBC. Materials and Methods: Two reviewers performed the search and assessed which articles were included. The quality of each study was evaluated according to QUADAS-2 and NOS. Meta-analysis of sensitivity and specificity was conducted with a bivariate random-effects model. The protocol was registered in PROSPERO, ID CRD42020199915. Results: Four studies involving 377 patients were included. Only stages F3 and F4 were computed in the meta-analysis. TE had a pooled sensitivity of 68% and specificity of 92% for stage F3 and a pooled sensitivity of 90% and specificity of 94% for stage F4. The AUROC curves were 0.91 (95% Confidence Interval (CI) 0.88–0.93) and 0.97 (95% CI 0.96–0.98) for stages F3 and F4, respectively. The mean cut-off points of TE for stage F3 were 9.28 kPa (95% CI 4.98–13.57) and for stage F4 were 15.2 kPa (95% CI 7.02–23.37). Conclusions: TE performance compared with liver biopsy in adult patients with PBC was excellent for staging liver fibrosis and was able to rule out cirrhosis in clinical practice.
    Keywords Liver cirrhosis ; Fibrosis ; elasticity imaging techniques ; Liver biopsy ; Primary biliary cholangitis ; Specialties of internal medicine ; RC581-951
    Subject code 610
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book: Obesidad

    Méndez-Sánchez, Nahum / Esquivel, Misael Uribe

    epidemiología, fisiopatología y manifestaciones clínicas

    2002  

    Author's details Nahum Méndez-Sánchez ; Misael Uribe Esquivel
    Language Spanish
    Size 329 S. : Ill., graph. Darst.
    Publisher Manual Moderno
    Publishing place Santafé de Bogotá
    Publishing country Mexico
    Document type Book
    HBZ-ID HT014318566
    ISBN 968-426-989-7 ; 978-968-426-989-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 A 939 order for loan Magazin

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  10. Article ; Online: Medical-legal implications of hepatitis C virus infection

    Misael Uribe

    Annals of Hepatology, Vol 5, Iss , Pp S74- (2006)

    2006  

    Keywords Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2006-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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