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Article ; Online: Corrosion behavior and degradation mechanism of micro-extruded 3D printed ordered pore topological Fe scaffolds.

Mishra, Dipesh Kumar / Pandey, Pulak Mohan

Journal of biomedical materials research. Part B, Applied biomaterials

2022  Volume 110, Issue 6, Page(s) 1439–1459

Abstract: The fabrication of ordered pore topological structures (OPTS) with an improved biodegradation profile offers unique attributes required for bone reconstruction. These attributes consisted of fully interconnected porous structure, bone-mimicking ... ...

Abstract The fabrication of ordered pore topological structures (OPTS) with an improved biodegradation profile offers unique attributes required for bone reconstruction. These attributes consisted of fully interconnected porous structure, bone-mimicking mechanical properties, and the possibility of fully regenerating bony defects. Most of the biomaterials based on magnesium were associated with the problem of too fast degradation rate. Here, the present aim was based on the fabrication of ordered pore topological Fe structures (OPTFS) using micro-extrusion-based 3D printing followed by pressureless microwave sintering. Two different kinds of pore features namely randomly distributed interconnected micropores and designed interconnected macropores were investigated. Static in vitro degradation results inferred that the H-2 mm pore size of hexagonal based ordered pore topological Fe structures (H-OPTFS) exhibited the highest degradation rate of 6.45 mg cm
MeSH term(s) Biocompatible Materials/chemistry ; Corrosion ; Iron/chemistry ; Porosity ; Printing, Three-Dimensional ; Tissue Scaffolds/chemistry
Chemical Substances Biocompatible Materials ; Iron (E1UOL152H7)
Language English
Publishing date 2022-02-03
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 2099992-6
ISSN 1552-4981 ; 1552-4973 ; 0021-9304
ISSN (online) 1552-4981
ISSN 1552-4973 ; 0021-9304
DOI 10.1002/jbm.b.35011
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