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  1. Article ; Online: Multicentric reticulohistiocytosis.

    Jain, Harsh / Vasdev, Vivek / S, Kartik / Kumar, Abhishek / Mishra, P S / J, Sankar / Chandwani, Ashish

    QJM : monthly journal of the Association of Physicians

    2024  

    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcae037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Role of qualitative contrast-enhanced ultrasound in the diagnosis of malignant breast lesions.

    Grewal, D S / Bhanu, K Uday / Sahni, Hirdesh / Maheshwari, Saurabh / Kakria, Neha / Mishra, P S / Anand, Varun

    Medical journal, Armed Forces India

    2022  Volume 79, Issue 4, Page(s) 414–420

    Abstract: Background: Carcinoma breast is the commonest cancer among women. Various authors have studied breast cancer with Contrast-Enhanced Ultrasound (CEUS) with promising results. Despite promising results, the additional cost of post-processing software ... ...

    Abstract Background: Carcinoma breast is the commonest cancer among women. Various authors have studied breast cancer with Contrast-Enhanced Ultrasound (CEUS) with promising results. Despite promising results, the additional cost of post-processing software limits its availability. In this study, we evaluated the utility of CEUS in differentiating malignant from benign breast lesions on regular ultrasound equipment without the use of dedicated software.
    Methods: We performed CEUS in 121 women with 121 breast lesions. CEUS was done by creating a custom preset on existing ultrasound equipment with the help of an application specialist authorized by the vendor. Lesions were evaluated qualitatively without the use of any commercial software. The pattern of enhancement i.e. homogenous, heterogeneous, peripheral, or no enhancement, and the number of penetrating vessels i.e., few or multiple were recorded. Results were compared with histopathological diagnosis.
    Results: There were a total of 121 breast lesions. The study showed sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 86.67 %, 54.10 %, 65 %, and 80.49% respectively for differentiating benign vs malignant lesions on the basis of the pattern of contrast enhancement. Using penetrating vessels for differentiating malignant lesions from benign lesions, the sensitivity, specificity, PPV, and NPV were found to be 64%, 67.86%, 78.05%, and 51.35% respectively.
    Conclusion: CEUS is useful in differentiating malignant from benign breast lesions. It can be easily performed by creating a custom preset on standard ultrasound equipment without the use of expensive software.
    Language English
    Publishing date 2022-03-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 196342-9
    ISSN 0377-1237
    ISSN 0377-1237
    DOI 10.1016/j.mjafi.2022.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A study to analyze the pattern of synovial lesions from synovial biopsies in a tertiary care centre.

    Tevatia, Manvir Singh / Goyal, Neeti / Baranwal, Ajay Kumar / Mishra, P S / Gupta, Arun / Sharma, Vyom / Agarwal, Mohit / Gupta, Prashant Sen / Dangwal, Vidhu

    Indian journal of pathology & microbiology

    2021  Volume 64, Issue 4, Page(s) 702–706

    Abstract: Introduction: Synovium has been documented as a primary site of inflammation and a major effector organ in a variety of joint diseases. Study of simple technique like synovial biopsy can help in early diagnosis and treatment of diseases significantly ... ...

    Abstract Introduction: Synovium has been documented as a primary site of inflammation and a major effector organ in a variety of joint diseases. Study of simple technique like synovial biopsy can help in early diagnosis and treatment of diseases significantly improving outcome of patient in cases of rheumatoid arthritis, osteoarthritis, etc., Only limited data exist on utility of synovial biopsies.
    Aim and objectives: To analyze the pattern of synovial lesions to differentiate between different kinds of arthritis. Also, to identify early stages of arthritis so as to prevent unnecessary invasive surgical procedure.
    Materials and methods: It's a retrospective study to analyze 103 cases of synovial lesions diagnosed in last five years at a tertiary care orthopedic center. All synovial biopsies obtained mainly by open method and few by arthroscopic method, that came to the Dept of Pathology were included. Lesions were classified into four categories that is, inflammatory joint diseases, degenerative joint diseases, tumor-like conditions and tumors.
    Results: Age group most affected was between 61 and 70 years, with male predominance. Osteoarthritis (OA) was the most common histopathological diagnosis. Early OA tissues showed greater lining layer thickness, vessel proliferation, and inflammation, while surface fibrin deposition along with fibrosis was noted in later stages.
    Conclusion: The histo-morphological observations made in this study may have important therapeutic implications for some patients during the early evolution of arthritis and could prevent unnecessary operative intervention of later stages.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Biopsy/statistics & numerical data ; Female ; Humans ; India ; Joint Diseases/diagnosis ; Joint Diseases/physiopathology ; Male ; Middle Aged ; Retrospective Studies ; Synovial Membrane/physiopathology ; Tertiary Care Centers/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2021-10-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 197621-7
    ISSN 0974-5130 ; 0377-4929
    ISSN (online) 0974-5130
    ISSN 0377-4929
    DOI 10.4103/IJPM.IJPM_498_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: In reply.

    Narang, P / Nagamiah, S / Das, S / Mishra, P S / Deotale, V / Mendiratta, D K

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2016  Volume 20, Issue 4, Page(s) 568

    Language English
    Publishing date 2016-04
    Publishing country France
    Document type Comment ; Journal Article
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.16.0009-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Drug susceptibility of rapid and slow growing non-tuberculous mycobacteria isolated from symptomatics for pulmonary tuberculosis, Central India.

    Goswami, B / Narang, P / Mishra, P S / Narang, R / Narang, U / Mendiratta, D K

    Indian journal of medical microbiology

    2016  Volume 34, Issue 4, Page(s) 442–447

    Abstract: Background: Non-tuberculous mycobacteria (NTM) are emerging as important pathogens. Their treatment also differs from that of Mycobacterium tuberculosis. In India, any datum on them is scarce as species identification and drug susceptibility are not ... ...

    Abstract Background: Non-tuberculous mycobacteria (NTM) are emerging as important pathogens. Their treatment also differs from that of Mycobacterium tuberculosis. In India, any datum on them is scarce as species identification and drug susceptibility are not performed in most laboratories. Susceptibility also differs from one geographic area to another, and in our country, there are no data even to guide the clinicians to start treatment empirically.
    Methodology: The present study endeavours to generate drug susceptibility data on NTM isolated from sputum samples collected and stored from 6445 symptomatics for pulmonary tuberculosis during a prevalence survey and from specimens received from the hospital. Isolates were not necessarily associated with the disease. Species were identified and antibiotic susceptibility was performed using micro-broth dilution technique as per the standard Clinical and Laboratory Standards Institute guidelines.
    Results: A total of 65 NTM with 11 species were identified, of which 27 belonged to Mycobacterium fortuitum complex, 14 Mycobacterium gordonae, 9 Mycobacterium avium, 7 Mycobacterium flavescens, 4 Mycobacterium scrofulaceum and one each of others. Sensitivity to amikacin for M. fortuitum was 95.22% (20 out of 21), followed by ciprofloxacin (76.19%) and clarithromycin (71.42%). All the 9 M. avium isolates, 11 of M. gordonae (78.57%), 5 of M. flavescens and 2 of M. scrofulaceum were sensitive to clarithromycin. All NTM were resistant to first-line antitubercular drugs except 8, which were sensitive to streptomycin.
    Conclusions: Drug sensitivity of NTM varies from species to species. While amikacin was the best for rapidly growing mycobacteria, clarithromycin was the most active drug against M. avium and other slow growers.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Humans ; India ; Microbial Sensitivity Tests ; Mycobacterium Infections, Nontuberculous/microbiology ; Nontuberculous Mycobacteria/drug effects ; Nontuberculous Mycobacteria/isolation & purification ; Sputum/microbiology ; Tuberculosis, Pulmonary/pathology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2016-10
    Publishing country India
    Document type Journal Article
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.4103/0255-0857.195375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Evaluation of variants of carbol fuchsin solution to stain acid-fast bacilli in-situ by the pot method.

    Das, S / Narang, P / Nagamiah, S / Mishra, P S / Deotale, V / Mendiratta, D K

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2015  Volume 19, Issue 12, Page(s) 1470–1475

    Abstract: Background: Ziehl-Neelsen (ZN) staining requires heating, and pre-stained smears contain viable bacilli.: Objective: To evaluate four variants of carbol fuchsin solution by the pot method and compare the results with ZN staining, taking culture as ... ...

    Abstract Background: Ziehl-Neelsen (ZN) staining requires heating, and pre-stained smears contain viable bacilli.
    Objective: To evaluate four variants of carbol fuchsin solution by the pot method and compare the results with ZN staining, taking culture as gold standard.
    Method: Five hundred sputum samples from presumptive tuberculosis cases were homogenised and divided into two parts. One part was subjected to routine ZN staining and culture on solid medium, the other was equally distributed into four pots. Equal quantities of the basic fuchsin (BF) variant were added to each pot. Variant I contained 2% BF with 10% phenol and 4% ammonium sulphate (PhAS), while Variant II had 0.6% BF with PhAS; Variants III and IV contained respectively 2% and 0.6% BF with 10% phenol only. After 1 h, smears were made from each pot and culture was performed on Löwenstein-Jensen medium. Smear results were compared with the ZN results and evaluated against culture.
    Results and conclusion: Variant III gave excellent results compared to ZN (κ = 0.97), with sensitivity, specificity, and positive and negative predictive values similar to those of ZN, taking culture as gold standard. Pot contents were negative for Mycobacterium tuberculosis culture.
    MeSH term(s) Coloring Agents/chemistry ; Culture Media ; Humans ; Mycobacterium tuberculosis/isolation & purification ; Rosaniline Dyes/chemistry ; Sensitivity and Specificity ; Sputum/microbiology ; Staining and Labeling/methods ; Tuberculosis, Pulmonary/diagnosis
    Chemical Substances Coloring Agents ; Culture Media ; Rosaniline Dyes ; carbol-fuchsin solution (4158315RUC)
    Language English
    Publishing date 2015-12
    Publishing country France
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.15.0272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: DNA fragment encoding MIH/VIH related peptide in giant freshwater prawn Macrobrachium rosenbergii (De Man)

    Singh, B / Mishra, P.S / Akare, S.J / Lakra, W.S

    Journal of aquaculture in the tropics. 2005 May, v. 20, no. 2

    2005  

    Keywords Macrobrachium rosenbergii ; shrimp culture ; hormone antagonists ; peptide hormones ; molting ; vitellogenesis ; inhibitors ; polymerase chain reaction ; gene amplification ; open reading frames ; DNA primers ; animal breeding
    Language English
    Dates of publication 2005-05
    Size p. 111-118.
    Document type Article
    ZDB-ID 58678-x
    ISSN 0970-0846
    ISSN 0970-0846
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Factors affecting egg production and egg weight in White Leghorn birds

    Mishra, P.S / Johar, K.S / Singh, A

    Indian veterinary medical journal. Dec 1988. v. 12 (4)

    1988  

    Keywords chickens ; strains ; egg production ; egg weight ; India
    Language English
    Dates of publication 1988-12
    Size p. 262-264.
    Document type Article
    ISSN 0250-5266
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Genetic study of age at first egg in White Leghorn strains

    Mishra, P.S / Johar, K.S / Singh, A

    Indian veterinary medical journal. Dec 1987. v. 11 (4)

    1987  

    Keywords chickens ; strains ; genetics ; age at first egg ; least squares
    Language English
    Dates of publication 1987-12
    Size p. 245-246.
    Document type Article
    ISSN 0250-5266
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: T suppressor cell index in transplant rejection.

    Tripathi, K / Sen, P C / Mishra, P S / Prakash, J

    Nephron

    1989  Volume 51, Issue 1, Page(s) 122–123

    MeSH term(s) Cell Count ; Graft Rejection ; Humans ; Kidney Transplantation ; T-Lymphocytes, Regulatory/pathology
    Language English
    Publishing date 1989
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 2235-3186 ; 1660-8151 ; 0028-2766
    ISSN (online) 1423-0186 ; 2235-3186
    ISSN 1660-8151 ; 0028-2766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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