LIVIVO - Search results -

Search results

Result 1 - 10 of total 96

Search options

Article: Qualitative exploration for the under-foot fall in utilization of health services at Primary Health Center of Shahdol, Madhya Pradesh.

Kabirpanthi, Vikrant / Gupta, Vikas / Mishra, Rohit / Ranjan, Rajesh

Journal of family medicine and primary care

2024 Volume 13, Issue 1, Page(s) 169–174

Abstract: Background: Despite efforts to improve healthcare infrastructure and service delivery, significant disparities in healthcare utilization persist, leading to suboptimal health outcomes and hindering progress toward achieving universal health coverage. ... ...

Abstract	Background: Despite efforts to improve healthcare infrastructure and service delivery, significant disparities in healthcare utilization persist, leading to suboptimal health outcomes and hindering progress toward achieving universal health coverage. This research article aims to conduct a qualitative exploration of the under-foot fall in utilization of health services, shedding light on the barriers and challenges faced by individuals in accessing and utilizing health care to inform targeted interventions and improve health service utilization. Methods: This qualitative study employed free listing, pile sorting, and focus group discussions (FGDs) as data collection methods. Representatives from various stakeholders involved in the primary healthcare delivery system were selected based on their vocalness, knowledge, willingness to participate, and heterogeneity of responses. Subsequently, FGDs and key informant interviews (KIIs) were conducted to further explore the identified barriers. The collected transcripts underwent manual thematic analysis using coding rules and theme generation procedures. Results: A total of 30 participants, including healthcare providers, community leaders, and individuals from the local community, took part in the qualitative exploration. The themes encompassed limited awareness and knowledge, geographical and infrastructural barriers, socioeconomic constraints, trust and perceptions of the healthcare system, and cultural and social factors. These findings provide valuable insights into the multifaceted barriers hindering healthcare utilization and can guide the development of targeted interventions and policies to improve healthcare access and delivery in the study area. Conclusion: The identified barriers, including limited awareness and knowledge, geographical and infrastructural challenges, socioeconomic constraints, trust and perceptions of the healthcare system, cultural and social factors, and gender disparities, are consistent with the existing literature.
Language	English
Publishing date	2024-02-08
Publishing country	India
Document type	Journal Article
ZDB-ID	2735275-4
ISSN	2278-7135 ; 2249-4863
ISSN (online)	2278-7135
ISSN	2249-4863
DOI	10.4103/jfmpc.jfmpc_823_23
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Singleton mutations in large-scale cancer genome studies: uncovering the tail of cancer genome.

Desai, Sanket / Ahmad, Suhail / Bawaskar, Bhargavi / Rashmi, Sonal / Mishra, Rohit / Lakhwani, Deepika / Dutt, Amit

NAR cancer

2024 Volume 6, Issue 1, Page(s) zcae010

Abstract: Singleton or low-frequency driver mutations are challenging to identify. We present a domain driver mutation estimator (DOME) to identify rare candidate driver mutations. DOME analyzes positions analogous to known statistical hotspots and resistant ... ...

Abstract	Singleton or low-frequency driver mutations are challenging to identify. We present a domain driver mutation estimator (DOME) to identify rare candidate driver mutations. DOME analyzes positions analogous to known statistical hotspots and resistant mutations in combination with their functional and biochemical residue context as determined by protein structures and somatic mutation propensity within conserved PFAM domains, integrating the CADD scoring scheme. Benchmarked against seven other tools, DOME exhibited superior or comparable accuracy compared to all evaluated tools in the prediction of functional cancer drivers, with the exception of one tool. DOME identified a unique set of 32 917 high-confidence predicted driver mutations from the analysis of whole proteome missense variants within domain boundaries across 1331 genes, including 1192 noncancer gene census genes, emphasizing its unique place in cancer genome analysis. Additionally, analysis of 8799 TCGA (The Cancer Genome Atlas) and in-house tumor samples revealed 847 potential driver mutations, with mutations in tyrosine kinase members forming the dominant burden, underscoring its higher significance in cancer. Overall, DOME complements current approaches for identifying novel, low-frequency drivers and resistant mutations in personalized therapy.
Language	English
Publishing date	2024-03-12
Publishing country	England
Document type	Journal Article
ISSN	2632-8674
ISSN (online)	2632-8674
DOI	10.1093/narcan/zcae010
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Gastrointestinal Lesions and Its Associated Factors in Adult Males With Iron Deficiency Anaemia: A Cross-Sectional Study From Tertiary Care Centre of North India.

Singh, Aishwarya / Mishra, Rohit / Ranjan, Rajesh

Cureus

2022 Volume 14, Issue 7, Page(s) e26905

Abstract: Background Around 30% of the world's population suffers from iron deficiency anaemia (IDA). The standard evaluation for IDA involves upper and lower endoscopy, which allows for the confirmation of pathology of the gastrointestinal tract (GIT) induced due ...

Abstract	Background Around 30% of the world's population suffers from iron deficiency anaemia (IDA). The standard evaluation for IDA involves upper and lower endoscopy, which allows for the confirmation of pathology of the gastrointestinal tract (GIT) induced due to IDA through iron malabsorption mechanism or loss of blood. Assessing the prevalence of lesions of GIT of significant nature among males having IDA, was the goal of our study. Methods Our cross-sectional study was conducted for two years and involved 152 males (adults) with confirmed cases of IDA from the Outpatient (OPD) and In-patient (IPD) in the present hospital. Following collecting consent (both informed and written in nature), patient-specific data was collected in a standardized form, and a blood sample was taken for laboratory testing. The analyses were done at a 5% level of significance; an association was considered significant if the p-value < 0.05. Results The average age of the study participants was 59.6 years. The commonest lesions reported were antral gastritis (9.9%) and H. pylori gastritis (7.2%) in upper GI; and haemorrhoid (9.2%) and anal fissure (3.9%) in lower GI. The overall prevalence of any GI lesions was 65.1%. The GI lesions were significantly associated higher among men with age > 50 years (73.7%). The presence of occult blood in stools (p < 0.0001) and parasites in stools (p=0.0001) were significantly related to the presence of GI lesions. Conclusion GI lesions are frequently detected in males with IDA. Whether it is symptomatic male or asymptomatic male with anaemia refractory to iron treatment, GIT should be evaluated in them.
Language	English
Publishing date	2022-07-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.26905
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Book ; Online: On Feature Scaling of Recursive Feature Machines

Gupta, Arunav / Mishra, Rohit / Luu, William / Bouassami, Mehdi

2023

Abstract: In this technical report, we explore the behavior of Recursive Feature Machines (RFMs), a type of novel kernel machine that recursively learns features via the average gradient outer product, through a series of experiments on regression datasets. When ... ...

Abstract	In this technical report, we explore the behavior of Recursive Feature Machines (RFMs), a type of novel kernel machine that recursively learns features via the average gradient outer product, through a series of experiments on regression datasets. When successively adding random noise features to a dataset, we observe intriguing patterns in the Mean Squared Error (MSE) curves with the test MSE exhibiting a decrease-increase-decrease pattern. This behavior is consistent across different dataset sizes, noise parameters, and target functions. Interestingly, the observed MSE curves show similarities to the "double descent" phenomenon observed in deep neural networks, hinting at new connection between RFMs and neural network behavior. This report lays the groundwork for future research into this peculiar behavior.
Keywords	Computer Science - Machine Learning ; Computer Science - Artificial Intelligence
Publishing date	2023-03-28
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: NMR-Based Metabolomic Imprinting Elucidates Macrophage Polarization of THP-1 Cell Lines Stimulated by Zinc Oxide Nanoparticles.

Mishra, Vani / Prajapati, Gurudayal / Baranwal, Vikas / Mishra, Rohit Kumar

ACS applied bio materials

2022

Abstract: Zinc oxide (ZnO) nanoparticles (NPs) have been widely used in industry, cosmetics, drugs, bioimaging, and drug delivery. ZnO NPs have been found to interact and interfere with cellular physiology via macrophages, thereby resulting in macrophage ... ...

Abstract	Zinc oxide (ZnO) nanoparticles (NPs) have been widely used in industry, cosmetics, drugs, bioimaging, and drug delivery. ZnO NPs have been found to interact and interfere with cellular physiology via macrophages, thereby resulting in macrophage polarization. The functional reprogramming of the cells is synchronized through cellular metabolic adaptations. The current study, therefore, aims to establish crosstalk between ZnO-NP-induced metabolic alterations and macrophage polarization in PMA-activated THP-1 cell lines. We observed moderate to heightened cytotoxic response in terms of cell viability and proliferation. The results also revealed increased Th1-type cytokine and chemokine expression. In order to characterize the changes in metabolite concentration in treatment groups, we employed multivariate data analysis (principal component analysis and partial least-squares discriminant analysis) of
Language	English
Publishing date	2022-09-20
Publishing country	United States
Document type	Journal Article
ISSN	2576-6422
ISSN (online)	2576-6422
DOI	10.1021/acsabm.2c00603
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Sparsity-based nonlinear reconstruction of optical parameters in two-photon photoacoustic computed tomography.

Gupta, Madhu / Mishra, Rohit Kumar / Roy, Souvik

Inverse problems

2021 Volume 37, Issue 4

Abstract: We present a new nonlinear optimization approach for the sparse reconstruction of single-photon absorption and two-photon absorption coefficients in the photoacoustic computed tomography (PACT). This framework comprises of minimizing an objective ... ...

Abstract	We present a new nonlinear optimization approach for the sparse reconstruction of single-photon absorption and two-photon absorption coefficients in the photoacoustic computed tomography (PACT). This framework comprises of minimizing an objective functional involving a least squares fit of the interior pressure field data corresponding to two boundary source functions, where the absorption coefficients and the photon density are related through a semi-linear elliptic partial differential equation (PDE) arising in PAT. Further, the objective functional consists of an
Language	English
Publishing date	2021-03-03
Publishing country	England
Document type	Journal Article
ZDB-ID	1477292-9
ISSN	1361-6420 ; 0266-5611
ISSN (online)	1361-6420
ISSN	0266-5611
DOI	10.1088/1361-6420/abdd0f
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Isolation and characterization of halotolerant plant growth promoting rhizobacteria from mangrove region of Sundarbans, India for enhanced crop productivity.

Pallavi / Mishra, Rohit Kumar / Sahu, Pramod Kumar / Mishra, Vani / Jamal, Hafiza / Varma, Ajit / Tripathi, Swati

Frontiers in plant science

2023 Volume 14, Page(s) 1122347

Abstract: Halotolerant plant growth promoting rhizobacteria (PGPR) are beneficial microorganisms utilized to mitigate the biotic and abiotic stresses in plants. The areas of Sundarban mangroves of West Bengal, India have been reported to be rich in halotolerant ... ...

Abstract	Halotolerant plant growth promoting rhizobacteria (PGPR) are beneficial microorganisms utilized to mitigate the biotic and abiotic stresses in plants. The areas of Sundarban mangroves of West Bengal, India have been reported to be rich in halotolerant microflora, yet major area remains unexplored. The present study, therefore, aims to map down the region-specific native microbial community potent of salt tolerance, plant growth promoting (PGP) activity and antagonistic activity against fungal pathogens. Bacterial samples were isolated from the saline soil of the Sundarban mangroves. A total of 156 bacterial samples were isolated and 20 were screened for their salt tolerance potential. These isolates were characterised using morphological, biochemical, and molecular approaches. Based on 16s rRNA sequencing, they were classified into 4 different genera, including
Language	English
Publishing date	2023-04-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2023.1122347
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: An Automated Centrifugal Microfluidic Platform for Efficient Multistep Blood Sample Preparation and Clean-Up towards Small Ion-Molecule Analysis.

Hou, Yuting / Mishra, Rohit / Zhao, Yufeng / Ducrée, Jens / Harrison, Jed D

Micromachines

2023 Volume 14, Issue 12

Abstract: Sample preparation for mass spectroscopy typically involves several liquid and solid phase clean-ups, extractions, and other unit operations, which are labour-intensive and error-prone. We demonstrate a centrifugal microfluidic platform that automates ... ...

Abstract	Sample preparation for mass spectroscopy typically involves several liquid and solid phase clean-ups, extractions, and other unit operations, which are labour-intensive and error-prone. We demonstrate a centrifugal microfluidic platform that automates the whole blood sample's preparation and clean-up by combining traditional liquid-phase and multiple solid-phase extractions for applications in mass spectroscopy (MS)-based small molecule detection. Liquid phase extraction was performed using methanol to precipitate proteins in plasma separated from a blood sample under centrifugal force. The preloaded solid phase composed of C18 beads then removed lipids with a combination of silica particles, which further cleaned up any remaining proteins. We further integrated the application of this sample prep disc with matrix-assisted laser desorption/ionization (MALDI) MS by using glancing angle deposition films, which further cleaned up the processed sample by segregating the electrolyte background from the sample salts. Additionally, hydrophilic interaction liquid chromatography (HILIC) MS was employed for detecting targeted free amino acids. Therefore, several representative ionic metabolites, including several amino acids and organic acids from blood samples, were analysed by both MALDI-MS and HILIC-MS to demonstrate the performance of this sample preparation disc. The fully automated blood sample preparation procedure only took 35 mins, with a throughput of three parallel units.
Language	English
Publishing date	2023-12-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2620864-7
ISSN	2072-666X
ISSN	2072-666X
DOI	10.3390/mi14122257
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Book: Heavy metals in plants

Kumar, Jitendra / Gaur, Shweta / Srivastava, Prabhat Kumar / Mishra, Rohit Kumar / Prasad, Sheo Mohan / Chauhan, D. K.

physiological to molecular approach

2022

Abstract: This book extensively focuses on the menace of metal pollution, its impact on plants particularly food grains, pulse and vegetable plants covering morphological, anatomical, physiological and biochemical aspects. It encompasses comparative study among ... ...

Author's details	editors, `Jitendra Kumar, Shweta Gaur, Prabhat Kumar Srivastava, Rohit Kumar Mishra, Sheo Mohan Prasad, Devendra Kumar Chauhan
Abstract	"This book extensively focuses on the menace of metal pollution, its impact on plants particularly food grains, pulse and vegetable plants covering morphological, anatomical, physiological and biochemical aspects. It encompasses comparative study among metal hyper-accumulators (metallophytes) and non-accumulators including exogenous hormonal alleviation in them due to metal stress. There will also be studies about low dose stimulation effects. The most significant feature of the book is its extensive coverage of genomics, metabolomics, ionomics, proteomics and transcriptomics in metal non-hyper-accumulators and hyper-accumulators. The compilation of different studies in the form of an edited book enriches the existing knowledge about metal pollution and opens newer avenues to be exercised"--
MeSH term(s)	Metals, Heavy
Keywords	Heavy metals. ; Plants/Effect of heavy metals on. ; Plants/Heavy metal content. ; Food crops/Effect of heavy metals on. ; Food crops/Heavy metal content.
Language	English
Dates of publication	2022-2022
Size	vi, 390 pages :, illustrations (some color), color map ;, 25 cm
Edition	First edition.
Publisher	CRC Press, Taylor & Francis Group
Publishing place	Boca Raton
Document type	Book
ISBN	9780367627393 ; 0367627396 ; 9781000652581 ; 9781000652550 ; 9781003110576 ; 0367627396 ; 9780367627393 ; 1000652580 ; 1000652556 ; 1003110576
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Supercritical CO2-assisted atomization for deposition of cellulose nanocrystals: an experimental and computational study

Shariatnia, Shadi / Jangale, Prajesh / Mishra, Rohit / Asadi, Amir / Jarrahbashi, Dorrin

Cellulose. 2022 Jan., v. 29, no. 2

2022

Abstract: Nanoparticle spray deposition finds numerous applications in pharmaceutical, electronics, manufacturing, and energy industries and has shown great promises in engineering the functional properties of the coated parts. However, current spray deposition ... ...

Abstract	Nanoparticle spray deposition finds numerous applications in pharmaceutical, electronics, manufacturing, and energy industries and has shown great promises in engineering the functional properties of the coated parts. However, current spray deposition systems either lack the required precision in controlling the morphology of the deposited nanostructures or do not have the capacity for large-scale deposition applications. In this study, we introduce a novel spray system that uses supercritical CO₂ to assist the atomization process and create uniform micron-size water droplets that are used as cellulose nanocrystal (CNC) carriers. CNCs are selected in this study as they are abundant, possess superior mechanical properties, and contain hydroxyl groups that facilitate interaction with neighboring materials. We fundamentally investigate the effect of different process parameters, such as injection pressure, gas-to-liquid ratio, the axial distance between the nozzle and substrate, and CNC concentration on the final patterns left on the substrate upon evaporation of water droplets. To this end, we show how tuning process parameters control the size of carrier droplets, dynamics of evaporation, and self-assembly of CNCs, which in turn dictate the final architecture of the deposited nanostructures. We will particularly investigate the morphology of the nanostructures deposited after evaporation of micron-size droplets that has not been fully disclosed to date. Different characterization techniques such as laser diffraction, polarized microscopy, and high-resolution profilometry are employed to visualize and quantify the effect of each process parameter. Numerical simulations are employed to inform the design of experiments. Finally, it is shown that the fabricated nanostructures can be engineered based on the size of the carrier droplets controlled by adjusting spray parameters and the concentration of nanoparticles in the injected mixture. Process parameters can be selected such that nanoparticles form a ring, disk, or dome-shaped structure. Moderate operational conditions, simplicity, and time efficiency of the process, and use of abundant and biodegradable materials, i.e., water, CNCs, and CO₂ promote the scalability and sustainability of this method.
Keywords	atomization ; biodegradability ; carbon dioxide ; cellulose ; electronics ; energy ; evaporation ; microscopy ; nanocrystals ; spray deposition
Language	English
Dates of publication	2022-01
Size	p. 1-22.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	1496831-9
ISSN	1572-882X ; 0969-0239
ISSN (online)	1572-882X
ISSN	0969-0239
DOI	10.1007/s10570-021-04368-7
Database	NAL-Catalogue (AGRICOLA)

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito