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  1. Article ; Online: Pure shift edited NMR methodologies for the extraction of Homo- and heteronuclear couplings with ultra-high resolution.

    Mishra, Sandeep Kumar / Suryaprakash, N

    Progress in nuclear magnetic resonance spectroscopy

    2023  Volume 136-137, Page(s) 1–60

    Abstract: The scalar couplings that result in the splitting of the signals in the NMR spectrum arise due to the interaction of the nuclear spins, whereby the spin polarization is transmitted through chemical bonds. The interaction strengths depend inter alia on ... ...

    Abstract The scalar couplings that result in the splitting of the signals in the NMR spectrum arise due to the interaction of the nuclear spins, whereby the spin polarization is transmitted through chemical bonds. The interaction strengths depend inter alia on the number of consecutive chemical bonds intervening between the two interacting spins and on the molecular conformation. The pairwise interaction of many spins in a molecule resulting in a complex spectrum poses a severe challenge to analyse the spectrum and hence the determination of magnitudes and signs of homo- and heteronuclear couplings. The problem is more severe in the analysis of
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 209325-x
    ISSN 1873-3301 ; 0079-6565
    ISSN (online) 1873-3301
    ISSN 0079-6565
    DOI 10.1016/j.pnmrs.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparison of preformed microcuff and preformed uncuffed endotracheal tubes in pediatric cleft palate surgery-A randomized controlled trial.

    Kamaladevi, Rithu Krishna / Mishra, Sandeep Kumar / Rudingwa, Priya / Mohapatra, Devi Prasad / Badhe, Ashok Shankar / Senthilnathan, Muthapillai

    Paediatric anaesthesia

    2024  Volume 34, Issue 4, Page(s) 340–346

    Abstract: Background and aims: Airway management in children with oral cleft surgery carries unique challenges, concerning the proximity of the surgical site and the tracheal tube. We hypothesized that using a Microcuff oral RAE tube would reduce tube exchange ... ...

    Abstract Background and aims: Airway management in children with oral cleft surgery carries unique challenges, concerning the proximity of the surgical site and the tracheal tube. We hypothesized that using a Microcuff oral RAE tube would reduce tube exchange and migration rate. We aimed to compare the performance of Microsoft and uncuffed oral performed tracheal tubes in children undergoing cleft palate surgeries regarding the rate of tracheal tube exchange, endobronchial intubation, and ventilatory parameters.
    Methods: One hundred children scheduled for cleft palate surgery were randomized into two groups. In the uncuffed group (n = 50), the tracheal tube was selected using the Modified Coles formula, and in the Microcuff (n = 50) group, the manufacturer's recommendations were followed. Intraoperatively, we compared the primary outcome of tube exchange using the chi-square test. The leak pressure and ventilatory parameters after head extension and mouth gag application were measured in both groups.
    Results: The tracheal tube exchange rate was significantly lower in the Microcuff group (0/50) than in uncuffed (19/50) preformed tubes (0 vs. 38% respectively; p <.001). The uncuffed and Microcuff tracheal tube were comparable concerning ventilation parameters and leak pressure of finally placed tubes (17.78 ± 3.95 vs. 19.26 ± 3.81 cm H
    Conclusion: Microcuff oral preformed tubes performed better than uncuffed tubes regarding tube exchange during cleft palate surgery.
    MeSH term(s) Child ; Humans ; Cleft Palate/surgery ; Respiration ; Airway Management ; Postoperative Period ; Intubation, Intratracheal
    Language English
    Publishing date 2024-01-08
    Publishing country France
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1086049-6
    ISSN 1460-9592 ; 1155-5645
    ISSN (online) 1460-9592
    ISSN 1155-5645
    DOI 10.1111/pan.14837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Molecular recognition and proteoglycan mimic arrangement: modulating cisplatin toxicity.

    Anand, Saurabh / Mardhekar, Sandhya / Bhoge, Preeti Ravindra / Mishra, Sandeep Kumar / Kikkeri, Raghavendra

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 33, Page(s) 4495–4498

    Abstract: We have demonstrated that cisplatin (CP), an anticancer drug, showed a preference for binding the sulfated-L-iduronic acid (S-L-IdoA) unit over the sulfated-D-glucuronic acid unit of heparan sulfate. The multivalency of S-L-IdoA, such as in the ... ...

    Abstract We have demonstrated that cisplatin (CP), an anticancer drug, showed a preference for binding the sulfated-L-iduronic acid (S-L-IdoA) unit over the sulfated-D-glucuronic acid unit of heparan sulfate. The multivalency of S-L-IdoA, such as in the proteoglycan mimic, resulted in distinct modes of cell-surface engineering in normal and cancer cells, with these disparities having a significant impact on CP-mediated toxicity.
    MeSH term(s) Proteoglycans ; Cisplatin ; Heparitin Sulfate/chemistry ; Glucuronic Acid/metabolism ; Iduronic Acid ; Sulfates
    Chemical Substances Proteoglycans ; Cisplatin (Q20Q21Q62J) ; Heparitin Sulfate (9050-30-0) ; Glucuronic Acid (8A5D83Q4RW) ; Iduronic Acid (3402-98-0) ; Sulfates
    Language English
    Publishing date 2024-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d4cc00464g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Transmembrane pH gradient imaging in rodent glioma models.

    Mishra, Sandeep Kumar / Santana, Jessica Gois / Mihailovic, Jelena / Hyder, Fahmeed / Coman, Daniel

    NMR in biomedicine

    2024  Volume 37, Issue 5, Page(s) e5102

    Abstract: A unique feature of the tumor microenvironment is extracellular acidosis in relation to intracellular milieu. Metabolic reprogramming in tumors results in overproduction of ... ...

    Abstract A unique feature of the tumor microenvironment is extracellular acidosis in relation to intracellular milieu. Metabolic reprogramming in tumors results in overproduction of H
    MeSH term(s) Rats ; Mice ; Animals ; Proton-Motive Force ; Brain Neoplasms/metabolism ; Rodentia ; Glioma/diagnostic imaging ; Brain/metabolism ; Magnetic Resonance Imaging/methods ; Hydrogen-Ion Concentration ; Tumor Microenvironment
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1000976-0
    ISSN 1099-1492 ; 0952-3480
    ISSN (online) 1099-1492
    ISSN 0952-3480
    DOI 10.1002/nbm.5102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Thoracic organ transplantation and pregnancy outcomes: systematic review and meta-analysis.

    Jha, Nivedita / Jha, Ajay Kumar / Mishra, Sandeep Kumar / Parida, Satyen

    Archives of gynecology and obstetrics

    2023  Volume 309, Issue 2, Page(s) 385–396

    Abstract: Purpose: Pre-conceptual comorbidities, an inherent risk of graft loss, rejection during pregnancy, and the postpartum period in women with thoracic lung transplant may predispose them to increased risk of adverse feto-maternal outcomes. The study aimed ... ...

    Abstract Purpose: Pre-conceptual comorbidities, an inherent risk of graft loss, rejection during pregnancy, and the postpartum period in women with thoracic lung transplant may predispose them to increased risk of adverse feto-maternal outcomes. The study aimed to systematically analyze and assess the risk of adverse pregnancy outcomes in women with thoracic organ transplant.
    Methods: MEDLINE, EMBASE, and Cochrane library were searched for publication between January 1990 and June 2020. Risk of bias was assessed using Joanna Briggs critical appraisal tool for case series. The primary outcomes included maternal mortality and pregnancy loss. The secondary outcomes were maternal complications, neonatal complications, and adverse birth outcomes. The analysis was performed using the DerSimonian-Laird random effects model.
    Results: Eleven studies captured data from 275 parturient with thoracic organ transplant describing 400 pregnancies. The primary outcomes included maternal mortality {pooled incidence (95% confidence interval) 4.2 (2.5-7.1) at 1 year and 19.5 (15.3-24.5) during follow-up}. Pooled estimates yielded 10.1% (5.6-17.5) and 21.8% (10.9-38.8) risk of rejection and graft dysfunction during and after pregnancy, respectively. Although 67% (60.2-73.2) of pregnancies resulted in live birth, total pregnancy loss and neonatal death occurred in 33.5% (26.7-40.9) and 2.8% (1.4-5.6), respectively. Prematurity and low birth weight were reported in 45.1% (38.5-51.9) and 42.7% (32.8-53.2), respectively.
    Conclusions: Despite pregnancies resulting in nearly 2/3rd of live births, high incidence of pregnancy loss, prematurity and low birth weight remain a cause of concern. Focused pre-conceptual counseling to avoid unplanned pregnancy, especially in women with transplant-related organ dysfunctions and complications, is vital to improve pregnancy outcomes.
    Prospero number: CRD42020164020.
    MeSH term(s) Female ; Humans ; Infant, Newborn ; Pregnancy ; Abortion, Spontaneous ; Infant, Low Birth Weight ; Infant, Premature ; Organ Transplantation/adverse effects ; Pregnancy Complications/etiology ; Pregnancy Outcome
    Language English
    Publishing date 2023-05-06
    Publishing country Germany
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-023-07065-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: WITHDRAWN: Assessment of the effect of particle size and selected physico-chemical and biological parameters on the efficiency and quality of composting of garden waste

    Mishra, Sandeep Kumar / Yadav, Kunwar.D.

    Heliyon. 2021,

    2021  

    Abstract: This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/ ... ...

    Abstract This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal
    Keywords compost quality ; garden residues ; particle size ; physicochemical properties ; yard waste composts
    Language English
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2021.e08415
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Application of locally available microbial inoculant to accelerate green waste composting at a community level

    Mishra, Sandeep Kumar / Yadav, Kunwar D.

    Bioresource technology reports. 2021 Dec., v. 16

    2021  

    Abstract: The present study investigates application of locally available microbial inoculants to accelerate green waste composting and selection of best inoculant based upon selected physico-chemical and biological parameters for 45 days composting duration. Five ...

    Abstract The present study investigates application of locally available microbial inoculants to accelerate green waste composting and selection of best inoculant based upon selected physico-chemical and biological parameters for 45 days composting duration. Five inoculants were prepared using cow-dung, cow-urine, jaggery, processed food waste, vegetable waste, and mature compost, each prepared in different ways named as C1, C2, C3, C4, C5 and C0 (control) and sprayed over 500 kg green waste and fed into aerated in-vessels. The blades of reactors provided adequate aeration to diverse microbial populations in different inoculants to degrade recalcitrant compounds resulting in high thermophilic phase duration (3–8 days), high volatile solid reduction (13–29%), high germination index (85–97%), fecal population < 1000, NPK value in range of N (1.6–2.4%) P (2.8–5.2 mg/kg) and K (6.2–9.3 mg/kg) and low C/N ratio (14.5–20.2). Performance of C1 inoculant (processed food waste) was most effective followed by C5 inoculant (vegetable waste).
    Keywords aeration ; composts ; cow manure ; food waste ; germination ; green waste ; jaggery ; technology ; vegetable residues
    Language English
    Dates of publication 2021-12
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 2589-014X
    DOI 10.1016/j.biteb.2021.100859
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Disposal of garden waste using food waste inoculant in rotary drums and their ranking using analytical hierarchy process

    Mishra, Sandeep Kumar / Yadav, Kunwar D

    Bioresource technology reports. 2021 Sept., v. 15

    2021  

    Abstract: The present study scientifically investigates the disposal of garden waste using food waste as an effective microbial inoculant. Fresh food waste was covered for seven days for development of fungus to boost lignin degradation. 100 kg garden waste was ... ...

    Abstract The present study scientifically investigates the disposal of garden waste using food waste as an effective microbial inoculant. Fresh food waste was covered for seven days for development of fungus to boost lignin degradation. 100 kg garden waste was shredded to particle size 0.5–1.5 cm diameter, mixed with 10 kg food waste inoculant and feed into rotary drum for 45 days composting period. Total volatile solids reduction, moisture reduction, CO₂ evolution rate, germination index, lignin degradation, coliforms reduction and changes in temperature were monitored. Cow-dung and fresh compost, easily available inoculants were also explored and investigated along with food waste inoculant to fasten the degradation process and to achieve the best combination. As per analytical hierarchy process, disposal of 100 kg garden waste with mixed combination of food waste, cow-dung and compost inoculant in (10:1:1:1) ratio proved to be best microbial inoculant combination for garden waste disposal.
    Keywords carbon dioxide ; composts ; cow manure ; drums (equipment) ; food waste ; fungi ; garden residues ; germination ; lignin ; particle size ; technology ; temperature ; waste disposal
    Language English
    Dates of publication 2021-09
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ISSN 2589-014X
    DOI 10.1016/j.biteb.2021.100710
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Relationship between difference of preoperative and cardiopulmonary bypass mean arterial pressure, and acute kidney injury in cardiac surgical patients undergoing valve surgery.

    Dhanyee, Anity Singh / Parida, Satyen / Thangaswamy, Chitra Rajeswari / Jha, Ajay Kumar / Rajappa, Medha / Munuswamy, Hemachandren / Mishra, Sandeep Kumar

    Perfusion

    2024  , Page(s) 2676591231226161

    Abstract: Background: Modifiable and non-modifiable factors contribute to development and progression of acute kidney injury (AKI) during cardiac surgery. We hypothesized that, the difference between preoperative mean arterial pressure (MAP) and the average mean ... ...

    Abstract Background: Modifiable and non-modifiable factors contribute to development and progression of acute kidney injury (AKI) during cardiac surgery. We hypothesized that, the difference between preoperative mean arterial pressure (MAP) and the average mean arterial pressure maintained on cardiopulmonary bypass (CPB) would be strongly predictive of AKI. We also measured plasma Neutrophil gelatinase-associated lipocalin (NGAL), to establish its association with cardiac surgery associated-AKI (CSA-AKI).
    Methods: One hundred and twelve high-risk patients undergoing valve, and valve plus coronary artery bypass grafting (CABG) surgery under cardiopulmonary bypass (CPB) were included in this study. Delta mean arterial pressure (MAP) was calculated as the difference between the average of pre-operative and on-bypass MAP, and blood was sampled for NGAL levels, at baseline, and 6-h after CPB. Detailed data collection was done, tabulating most of the factors which might influence development of post-operative cardiac surgery associated-AKI (CSA-AKI). To define CSA-AKI within the first 24-h post-operatively, the Kidney Disease Improving Global Outcomes (KDIGO) classification was used.
    Results: Out of 112 patients, 44 (39.3%) developed CSA-AKI postoperatively. With an ROC analysis cut-off of delta MAP of more than 25.67 mmHg, 46.4% patients developed post-operative AKI, and the average CPB flows which were 1.8 ± 0.2 were not contributory to the development of early CSA-AKI. In our study, ELISA test for human NGAL was performed on serum samples, and the estimated cut-off value of 1661 ng/mL was found to be significantly associated with early CSA-AKI.
    Conclusions: Delta MAP and CPB flows are not related to early post-surgical CSA-AKI in cases with prior high-risk elements. However, baseline serum NGAL, as well as its percent change during the early post-surgical period independently predicted the development of CSA-AKI. This implies that, there may be patients with a higher pre-operative preponderance to develop this complication, which could actually be delineated by the use of serum NGAL estimations at baseline.
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/02676591231226161
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  10. Article ; Online: Correction: Mishra, S.K. and Suryaprakash, N. Intramolecular Hydrogen Bonding Involving Organic Fluorine: NMR Investigations Corroborated by DFT-Based Theoretical Calculations:

    Mishra, Sandeep Kumar / Suryaprakash, N

    Molecules (Basel, Switzerland)

    2019  Volume 24, Issue 10

    Abstract: The authors wish to make the following corrections to their paper [ ... ]. ...

    Abstract The authors wish to make the following corrections to their paper [...].
    Language English
    Publishing date 2019-05-24
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules24102000
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