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  1. Article: Causes of Suboptimal Preoxygenation Before Tracheal Intubation in Elective and Emergency Abdominal Surgery

    Kauzonas, Evaldas / Kalinauskaitė, Miglė / Miškinytė, Sigutė / Bubulytė, Silvija / Kontrimavičiūtė, Eglė

    Proceedings of the Latvian Academy of Sciences. 2022 June 01, v. 76, no. 3

    2022  

    Abstract: Optimal preoxygenation (PO) prior to tracheal intubation reduces the risk of arterial desaturation and prolongs the period of safe apnoea. The common methods of PO are mask ventilation with 100% O₂ for 3–5 minutes or, alternatively, asking the patient to ...

    Abstract Optimal preoxygenation (PO) prior to tracheal intubation reduces the risk of arterial desaturation and prolongs the period of safe apnoea. The common methods of PO are mask ventilation with 100% O₂ for 3–5 minutes or, alternatively, asking the patient to take eight deep breaths in a minute. Our study group conducted a prospective study to assess the impact of the most common risk factors on PO and to compare the efficiency of PO in patients undergoing elective and emergency abdominal surgery without premedication. PO was performed using mask ventilation with 6 l/min of 100% oxygen for 5 minutes. End-tidal oxygen (EtO₂) was documented in 30-second increments. We found that optimal PO (EtO₂ > 90%) was not achieved by almost half of the patients (46%) and that this was more common in the elective surgery group. Effective PO was not impacted by any of the evaluated risk factors for suboptimal oxygenation. Despite these findings, we believe that the identification of potential risk factors is crucial in the pre-anaesthesia stage, given the benefits of optimal PO.
    Keywords oxygen ; patients ; prospective studies ; surgery
    Language English
    Dates of publication 2022-0601
    Size p. 361-365.
    Publishing place Sciendo
    Document type Article
    ISSN 2255-890X
    DOI 10.2478/prolas-2022-0055
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Role of Fat-Free Mass Index on Amino Acid Loss during CRRT in Critically Ill Patients.

    Vicka, Vaidas / Vickiene, Alvita / Miskinyte, Sigute / Bartuseviciene, Ieva / Lisauskiene, Ingrida / Serpytis, Mindaugas / Ringaitiene, Donata / Sipylaite, Jurate

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 2

    Abstract: Background and objectives: ...

    Abstract Background and objectives:
    MeSH term(s) Humans ; Middle Aged ; Aged ; Continuous Renal Replacement Therapy ; Prospective Studies ; Critical Illness ; Amino Acids ; Critical Care ; Acute Kidney Injury/therapy ; Retrospective Studies
    Chemical Substances Amino Acids
    Language English
    Publishing date 2023-02-17
    Publishing country Switzerland
    Document type Observational Study ; Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59020389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  3. Article ; Online: Comparison of mortality risk evaluation tools efficacy in critically ill COVID-19 patients.

    Vicka, Vaidas / Januskeviciute, Elija / Miskinyte, Sigute / Ringaitiene, Donata / Serpytis, Mindaugas / Klimasauskas, Andrius / Jancoriene, Ligita / Sipylaite, Jurate

    BMC infectious diseases

    2021  Volume 21, Issue 1, Page(s) 1173

    Abstract: Background: As the COVID-19 pandemic continues, the number of patients admitted to the intensive care unit (ICU) is still increasing. The aim of our article is to estimate which of the conventional ICU mortality risk scores is the most accurate at ... ...

    Abstract Background: As the COVID-19 pandemic continues, the number of patients admitted to the intensive care unit (ICU) is still increasing. The aim of our article is to estimate which of the conventional ICU mortality risk scores is the most accurate at predicting mortality in COVID-19 patients and to determine how these scores can be used in combination with the 4C Mortality Score.
    Methods: This was a retrospective study of critically ill COVID-19 patients treated in tertiary reference COVID-19 hospitals during the year 2020. The 4C Mortality Score was calculated upon admission to the hospital. The Simplified Acute Physiology Score (SAPS) II, Acute Physiology and Chronic Health Evaluation (APACHE) II, and Sequential Organ Failure Assessment (SOFA) scores were calculated upon admission to the ICU. Patients were divided into two groups: ICU survivors and ICU non-survivors.
    Results: A total of 249 patients were included in the study, of which 63.1% were male. The average age of all patients was 61.32 ± 13.3 years. The all-cause ICU mortality ratio was 41.4% (n = 103). To determine the accuracy of the ICU mortality risk scores a ROC-AUC analysis was performed. The most accurate scale was the APACHE II, with an AUC value of 0.772 (95% CI 0.714-0.830; p < 0.001). All of the ICU risk scores and 4C Mortality Score were significant mortality predictors in the univariate regression analysis. The multivariate regression analysis was completed to elucidate which of the scores can be used in combination with the independent predictive value. In the final model, the APACHE II and 4C Mortality Score prevailed. For each point increase in the APACHE II, mortality risk increased by 1.155 (OR 1.155, 95% CI 1.085-1.229; p < 0.001), and for each point increase in the 4C Mortality Score, mortality risk increased by 1.191 (OR 1.191, 95% CI 1.086-1.306; p < 0.001), demonstrating the best overall calibration of the model.
    Conclusions: The study demonstrated that the APACHE II had the best discrimination of mortality in ICU patients. Both the APACHE II and 4C Mortality Score independently predict mortality risk and can be used concomitantly.
    MeSH term(s) Aged ; COVID-19 ; Critical Illness ; Hospital Mortality ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Pandemics ; Prognosis ; ROC Curve ; Retrospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2021-11-22
    Publishing country England
    Document type Journal Article
    ISSN 1471-2334
    ISSN (online) 1471-2334
    DOI 10.1186/s12879-021-06866-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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