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  1. Book ; Online: Handbook of nutrition and the kidney

    Ikizler, T. Alp / Mitch, William E.

    2018  

    Author's details edited by T. Alp Ikizler, MD; William E. Mitch, MD
    Keywords Kidney Diseases / diet therapy ; Kidney Diseases / metabolism ; Nutritional Requirements
    Language English
    Size 1 Online-Ressource (272 Seiten), Illustrationen
    Edition Seventh edition
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia
    Publishing country United States
    Document type Book ; Online
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020142675
    ISBN 978-1-4963-5581-2 ; 1-4963-5581-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Handbook of nutrition and the kidney

    Mitch, William E. / Ikizler, T. Alp

    2010  

    Author's details [edited by] William E. Mitch, T. Alp Ikizler
    Keywords Kidney diseases - diet therapy ; Kidney diseases - metabolism ; Nutritional requirements ; Handbooks
    Language English
    Size 1 Online-Ressource (xiii, 322 Seiten), Illustrationen
    Edition 6th ed.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia, Pa
    Document type Book ; Online
    Note Includes bibliographical references and index
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-0-7817-9517-3 ; 0-7817-9517-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Does Serum Creatinine Reflect Muscle Mass in Patients with Kidney Failure?

    Navaneethan, Sankar D / Mitch, William E

    Journal of the American Society of Nephrology : JASN

    2023  Volume 35, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Creatinine ; Kidney ; Renal Insufficiency/complications ; Muscles ; Glomerular Filtration Rate
    Chemical Substances Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Handbook of nutrition and the kidney

    Mitch, William E.

    (A Lippincott Williams & Wilkins handbook)

    2002  

    Author's details ed. William E. Mitch
    Series title A Lippincott Williams & Wilkins handbook
    Keywords Kidney diseases / diet therapy ; Nutrition ; Nutritional Requirements
    Language English
    Size XI, 356 S. : Ill., graph. Darst.
    Edition 4. ed.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT013380000
    ISBN 0-7817-3644-7 ; 978-0-7817-3644-2
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Nutrition and the kidney

    Mitch, William E.

    1993  

    Author's details ed. by William E. Mitch
    Keywords Kidney Diseases ; Nutritional Requirements ; Niere ; Ernährung
    Subject Nutrition ; Ernährungsstatus ; Ernährungszustand ; Nephros ; Ren
    Language English
    Size XIII, 468 S. : graph. Darst.
    Edition 2. ed.
    Publisher Little, Brown
    Publishing place Boston u.a.
    Publishing country United States
    Document type Book
    New title 3. Aufl. u.d.T. Handbook of nutrition and the kidney
    HBZ-ID HT006205012
    ISBN 0-316-57500-3 ; 978-0-316-57500-3
    Database Catalogue ZB MED Medicine, Health

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  6. Book: The progressive nature of renal disease

    Mitch, William E.

    (Contemporary issues in nephrology ; 26)

    1992  

    Author's details guest ed. William E. Mitch
    Series title Contemporary issues in nephrology ; 26
    Collection
    Keywords Kidney Diseases / physiopathology ; Chronische Niereninsuffizienz ; Pathophysiologie
    Subject Pathologische Physiologie ; Physiologische Pathologie ; Physiopathologie ; Chronisches Nierenversagen ; Chronische Nierenfunktionsstörung
    Size XVI, 288 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Churchill Livingstone
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT004954067
    ISBN 0-443-08819-5 ; 978-0-443-08819-3
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Muscle Atrophy in CKD: A Historical Perspective of Advancements in Its Understanding.

    Price, S Russ / Mitch, William E / Garibotto, Giacomo

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

    2022  Volume 33, Issue 6S, Page(s) S88–S92

    Abstract: Objective: This perspective reviews the seminal clinical and experimental observations that led to today's current mechanistic model of muscle protein loss (wasting) in patients with chronic kidney disease (CKD).: Results and conclusion: Early ... ...

    Abstract Objective: This perspective reviews the seminal clinical and experimental observations that led to today's current mechanistic model of muscle protein loss (wasting) in patients with chronic kidney disease (CKD).
    Results and conclusion: Early International Society of Renal Nutrition and Metabolism (ISRNM) meetings facilitated discussions and hypotheses about the causes of muscle wasting in CKD. It became widely recognized that wasting is common and correlated with increased risks of mortality and morbidity. Although anorexia and dietary restrictions contribute to muscle loss, several features of CKD-associated wasting cannot be explained by malnutrition alone. The protein catabolism-inducing actions of metabolic acidosis, inflammation, insulin resistance, endocrine disorders and uremic toxins were progressively identified. Continued research to understand the interactions of inflammation, anabolic resistance, mitochondrial dysfunction, exercise, and nutrition on muscle protein turnover in patients with CKD will hopefully accelerate discoveries and treatments to ameliorate muscle wasting as well as the progression of CKD.
    MeSH term(s) Humans ; Renal Insufficiency, Chronic ; Muscular Atrophy ; Cachexia ; Muscle Proteins ; Inflammation/complications
    Chemical Substances Muscle Proteins
    Language English
    Publishing date 2022-09-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1080003-7
    ISSN 1532-8503 ; 1051-2276
    ISSN (online) 1532-8503
    ISSN 1051-2276
    DOI 10.1053/j.jrn.2022.09.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Nutrition and the kidney

    Mitch, William E.

    1988  

    Author's details ed. by William E. Mitch
    Keywords Kidney Diseases ; Nutritional Requirements ; Nutrition ; Niere ; Ernährung
    Subject Nutrition ; Ernährungsstatus ; Ernährungszustand ; Nephros ; Ren
    Size XI, 363 S. : graph. Darst.
    Publisher Little, Brown and Co
    Publishing place Boston u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT003571396
    ISBN 0-316-57499-6 ; 978-0-316-57499-0
    Database Catalogue ZB MED Medicine, Health

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  9. Book: The progressive nature of renal disease

    Mitch, William E.

    (Contemporary issues in nephrology ; 14)

    1986  

    Author's details guest ed. William E. Mitch
    Series title Contemporary issues in nephrology ; 14
    Collection
    Keywords Kidney Diseases ; Chronische Niereninsuffizienz ; Pathophysiologie
    Subject Pathologische Physiologie ; Physiologische Pathologie ; Physiopathologie ; Chronisches Nierenversagen ; Chronische Nierenfunktionsstörung
    Size XII, 293 S. : Ill., graph. Darst.
    Edition 1. [Dr.]
    Publisher Churchill Livingstone
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT002937993
    ISBN 0-443-08373-8 ; 978-0-443-08373-0
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Pathophysiological mechanisms leading to muscle loss in chronic kidney disease.

    Wang, Xiaonan H / Mitch, William E / Price, S Russ

    Nature reviews. Nephrology

    2021  Volume 18, Issue 3, Page(s) 138–152

    Abstract: Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that causes a decrease in muscle strength and function, and can lead to a reduction in quality of life and increased risk of morbidity and mortality. The effectiveness ... ...

    Abstract Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that causes a decrease in muscle strength and function, and can lead to a reduction in quality of life and increased risk of morbidity and mortality. The effectiveness of current treatment strategies in preventing or reversing muscle protein losses is limited. The limitations largely stem from the systemic nature of diseases such as CKD, which stimulate skeletal muscle protein degradation pathways while simultaneously activating mechanisms that impair muscle protein synthesis and repair. Stimuli that initiate muscle protein loss include metabolic acidosis, insulin and IGF1 resistance, changes in hormones, cytokines, inflammatory processes and decreased appetite. A growing body of evidence suggests that signalling molecules secreted from muscle can enter the circulation and subsequently interact with recipient organs, including the kidneys, while conversely, pathological events in the kidney can adversely influence protein metabolism in skeletal muscle, demonstrating the existence of crosstalk between kidney and muscle. Together, these signals, whether direct or indirect, induce changes in the levels of regulatory and effector proteins via alterations in mRNAs, microRNAs and chromatin epigenetic responses. Advances in our understanding of the signals and processes that mediate muscle loss in CKD and other muscle wasting conditions will support the future development of therapeutic strategies to reduce muscle loss.
    MeSH term(s) Humans ; MicroRNAs/metabolism ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Muscular Atrophy ; Quality of Life ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/metabolism
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2021-11-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2490366-8
    ISSN 1759-507X ; 1759-5061
    ISSN (online) 1759-507X
    ISSN 1759-5061
    DOI 10.1038/s41581-021-00498-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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