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  1. Book ; Online: Chapter The cost-effectiveness of what in health and care?

    Mitchell, Paul Mark

    2021  

    Keywords Health economics ; health economics, QALY, capability approach
    Language 0|e
    Size 1 electronic resource (23 pages)
    Publisher Kohlhammer Verlag
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021609037
    ISBN 9783170381766 ; 3170381768
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Key Insights into Developing Qualitative Concept Elicitation Work for Outcome Measures with Children and Young People.

    Husbands, Samantha / Mitchell, Paul Mark / Coast, Joanna

    The patient

    2024  Volume 17, Issue 3, Page(s) 219–227

    Abstract: Qualitative concept elicitation can develop meaningful patient-reported outcome measures for children and young people; however, the methods used for concept elicitation are often underreported for this population. This paper provides in-depth insight ... ...

    Abstract Qualitative concept elicitation can develop meaningful patient-reported outcome measures for children and young people; however, the methods used for concept elicitation are often underreported for this population. This paper provides in-depth insight into the methods used for concept elicitation with children and young people, with a focus on key stages of concept elicitation that are challenging or unique to doing this research with children. Drawing on our experiences of developing wellbeing measures for children and young people aged 6-15 years, we detail the processes followed in our qualitative concept elicitation work, covering issues related to sampling and recruitment, encouraging informed assent and freedom over children and young people's involvement in concept elicitation, and the use of creative and participatory methods to develop measure items. We provide reflections on the approaches taken to navigate challenging aspects of concept elicitation with children and young people. Our reflections suggest that using existing links and online recruitment methods can help to navigate organisational gatekeepers, and using appropriate processes to develop study information and obtain informed assent can ensure that research is inclusive and that children have the freedom to decide whether to be involved. Our adaptation of a creative and participatory activity to generate concepts for measure items suggests that such approaches can be engaging and may help to give children greater control over their participation. In detailing our methods, we hope to have developed a useful resource for other researchers, while highlighting the value of transparent reporting in this area.
    MeSH term(s) Humans ; Adolescent ; Child ; Qualitative Research ; Patient Reported Outcome Measures ; Male ; Female
    Language English
    Publishing date 2024-02-14
    Publishing country New Zealand
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2466680-4
    ISSN 1178-1661 ; 1178-1653
    ISSN (online) 1178-1661
    ISSN 1178-1653
    DOI 10.1007/s40271-023-00663-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Is well-becoming important for children and young people? Evidence from in-depth interviews with children and young people and their parents.

    Husbands, Samantha / Mitchell, Paul Mark / Kinghorn, Philip / Byford, Sarah / Bailey, Cara / Anand, Paul / Peters, Tim J / Floredin, Isabella / Coast, Joanna

    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

    2024  Volume 33, Issue 4, Page(s) 1051–1061

    Abstract: Purpose: This study explores how important well-becoming factors appear to be to children during childhood. We define well-becoming as the indicators which predict children and young people's future wellbeing and opportunities. The priority for this ... ...

    Abstract Purpose: This study explores how important well-becoming factors appear to be to children during childhood. We define well-becoming as the indicators which predict children and young people's future wellbeing and opportunities. The priority for this work was to explore whether well-becoming might be an important factor to include in outcome measures for children and young people. The inclusion of well-becoming indicators could ensure that opportunities to invest in promoting wellbeing in children's futures are not missed.
    Methods: In-depth, qualitative interviews (N = 70) were undertaken with children and young people aged 6-15 years and their parents. Analysis used constant comparison and framework methods to investigate whether well-becoming factors were considered important by informants to children and young people's current wellbeing.
    Results: The findings of the interviews suggested that children and young people and their parents are concerned with future well-becoming now, as factors such as future achievement, financial security, health, independence, identity, and relationships were identified as key to future quality of life. Informants suggested that they considered it important during childhood to aspire towards positive outcomes in children and young people's futures.
    Conclusion: The study findings, taken alongside relevant literature, have generated evidence to support the notion that future well-becoming is important to current wellbeing. We have drawn on our own work in capability wellbeing measure development to demonstrate how we have incorporated a well-becoming attribute into our measures. The inclusion of well-becoming indicators in measures could aid investment in interventions which more directly improve well-becoming outcomes for children and young people.
    MeSH term(s) Child ; Humans ; Adolescent ; Quality of Life/psychology ; Parents ; Outcome Assessment, Health Care
    Language English
    Publishing date 2024-01-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1161148-0
    ISSN 1573-2649 ; 0962-9343
    ISSN (online) 1573-2649
    ISSN 0962-9343
    DOI 10.1007/s11136-023-03585-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3796: Show issues Location:
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  4. Article ; Online: A Systematic Review of the Use and Quality of Qualitative Methods in Concept Elicitation for Measures with Children and Young People.

    Husbands, Samantha / Mitchell, Paul Mark / Coast, Joanna

    The patient

    2020  Volume 13, Issue 3, Page(s) 257–288

    Abstract: Background: Qualitative research is recommended in concept elicitation for patient-reported outcome measures to ensure item content validity, and those developing measures are encouraged to report qualitative methods in detail. However, in measure ... ...

    Abstract Background: Qualitative research is recommended in concept elicitation for patient-reported outcome measures to ensure item content validity, and those developing measures are encouraged to report qualitative methods in detail. However, in measure development for children and young people, direct research can be challenging due to problems with engagement and communication.
    Objectives: The aim of this systematic review was to (i) explore the qualitative and adapted data collection techniques that research teams have used with children and young people to generate items in existing measures and (ii) assess the quality of qualitative reporting.
    Methods: Three electronic databases were searched with forward citation and reference list searching of key papers. Papers included in the review were empirical studies documenting qualitative concept elicitation with children and young people. Data on qualitative methods were extracted, and all studies were checked against a qualitative reporting checklist.
    Results: A total of 37 studies were included. The quality of reporting of qualitative approaches for item generation was low, with information missing on sampling, data analysis and the research team, all of which are key to facilitating judgements around measure content validity. Few papers reported adapting methods to be more suitable for children and young people, potentially missing opportunities to more meaningfully engage children in concept elicitation work.
    Conclusions: Research teams should ensure that they are documenting detailed and transparent processes for concept elicitation. Guidelines are currently lacking in the development and reporting of item generation for children, with this being an important area for future research.
    MeSH term(s) Adolescent ; Child ; Female ; Humans ; Male ; Patient Reported Outcome Measures ; Qualitative Research
    Language English
    Publishing date 2020-04-28
    Publishing country New Zealand
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2466680-4
    ISSN 1178-1661 ; 1178-1653
    ISSN (online) 1178-1661
    ISSN 1178-1653
    DOI 10.1007/s40271-020-00414-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Estimating loss in capability wellbeing in the first year of the COVID-19 pandemic: a cross-sectional study of the general adult population in the UK, Australia and the Netherlands.

    Mitchell, Paul Mark / Morton, Rachael L / Hiligsmann, Mickaël / Husbands, Samantha / Coast, Joanna

    The European journal of health economics : HEPAC : health economics in prevention and care

    2022  Volume 24, Issue 4, Page(s) 609–619

    Abstract: Objectives: To estimate capability wellbeing lost from the general adult populations in the UK, Australia and the Netherlands in the first year of the COVID-19 pandemic and the associated social restrictions, including lockdowns.: Design: Cross- ... ...

    Abstract Objectives: To estimate capability wellbeing lost from the general adult populations in the UK, Australia and the Netherlands in the first year of the COVID-19 pandemic and the associated social restrictions, including lockdowns.
    Design: Cross-sectional with recalled timepoints.
    Setting: Online panels in the UK, Australia and the Netherlands conducted in February 2021 (data collected 26 January-2 March 2021).
    Participants: Representative general adult (≥ 18 years old) population samples in the UK (n = 1,017), Australia (n = 1,011) and the Netherlands (n = 1,017) MAIN OUTCOME MEASURE: Participants completed the ICECAP-A capability wellbeing measure in February 2021, and for two recalled timepoints during the initial lockdowns in April 2020 and in February 2020 (prior to COVID-19 restrictions in all three countries). ICECAP-A scores on a 0-1 no capability-full capability scale were calculated for each timepoint. Societal willingness to pay estimates for a year of full capability (YFC) was used to place a monetary value associated with change in capability per person and per country. Paired t tests were used to compare changes in ICECAP-A and YFC from pre- to post-COVID-19-related restrictions in each country.
    Results: Mean (standard deviation) loss of capability wellbeing during the initial lockdown was 0.100 (0.17) in the UK, 0.074 (0.17) in Australia and 0.049 (0.12) in the Netherlands. In February 2021, losses compared to pre-lockdown were 0.043 (0.14) in the UK, 0.022 (0.13) in Australia and 0.006 (0.11) in the Netherlands. In monetary terms, these losses were equivalent to £14.8 billion, AUD$8.6 billion and €2.1 billion lost per month in April 2020 and £6.4 billion, A$2.6 billion and €260 million per month in February 2021 for the UK, Australia and the Netherlands, respectively.
    Conclusions: There were substantial losses in capability wellbeing in the first year of the COVID-19 pandemic. Future research is required to understand the specific impact of particular COVID-19 restrictions on people's capabilities.
    MeSH term(s) Humans ; Adult ; Adolescent ; COVID-19/epidemiology ; Cross-Sectional Studies ; Netherlands/epidemiology ; Pandemics ; Communicable Disease Control ; Australia/epidemiology ; United Kingdom/epidemiology
    Language English
    Publishing date 2022-07-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2045253-6
    ISSN 1618-7601 ; 1618-7598
    ISSN (online) 1618-7601
    ISSN 1618-7598
    DOI 10.1007/s10198-022-01498-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5475: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Measuring capability wellbeing in adults at different stages of life for use in economic evaluation of health and care interventions: a qualitative investigation in people requiring kidney care.

    Mitchell, Paul Mark / Husbands, Samantha / Sanghera, Sabina / Caskey, Fergus John / Scott, Jemima / Coast, Joanna

    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

    2021  Volume 30, Issue 10, Page(s) 2863–2873

    Abstract: Purpose: Capability wellbeing measures, such as the ICECAP measures, have been proposed for use in economic evaluations to capture broader outcomes of health and care interventions. The ICECAP measures have been developed to reflect capabilities at ... ...

    Abstract Purpose: Capability wellbeing measures, such as the ICECAP measures, have been proposed for use in economic evaluations to capture broader outcomes of health and care interventions. The ICECAP measures have been developed to reflect capabilities at different stages of life. Some patient groups include patients of different ages and at different stages of life, so it is not always apparent which ICECAP measure is most relevant. This study explores the impact of age and life stage on completion, where both ICECAP-A and ICECAP-O were completed by the same patient.
    Methods: A think-aloud study, and an associated semi-structured interview were conducted with people receiving kidney care as a renal outpatient, kidney transplant outpatient, or through receiving facility-based haemodialysis. Qualitative analysis focused on (1) differences in responses across measures by individuals, where attributes had conceptual overlap, (2) key factors in self-reported capability levels, and (3) measure preference.
    Results: Thirty participants were included in the study, with a mix of older and younger adults. Attributes with similar wording across measures produced similar responses compared to attributes where wording differed. Age and health were key factors for self-reported capability levels. ICECAP-A was slightly preferred overall, including by older adults.
    Conclusion: This study suggests use of ICECAP-A in patients with certain chronic health conditions that include a mix of adults across the life course. This study highlights the importance of considering the stage of life when using capability measures and in economic evaluations of health and care interventions more generally.
    MeSH term(s) Aged ; Cost-Benefit Analysis ; Humans ; Kidney ; Quality of Life/psychology ; Self Report ; Surveys and Questionnaires
    Language English
    Publishing date 2021-05-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1161148-0
    ISSN 1573-2649 ; 0962-9343
    ISSN (online) 1573-2649
    ISSN 0962-9343
    DOI 10.1007/s11136-021-02851-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3796: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Response process validity of three patient reported outcome measures for people requiring kidney care: a think-aloud study using the EQ-5D-5L, ICECAP-A and ICECAP-O.

    Mitchell, Paul Mark / Caskey, Fergus John / Scott, Jemima / Sanghera, Sabina / Coast, Joanna

    BMJ open

    2020  Volume 10, Issue 5, Page(s) e034569

    Abstract: Objectives: To determine the response process validity, feasibility of completion, acceptability and preferences for three patient-reported outcome measures that could be used in economic evaluation-the EQ-5D-5L, ICECAP-A and ICECAP-O-in people ... ...

    Abstract Objectives: To determine the response process validity, feasibility of completion, acceptability and preferences for three patient-reported outcome measures that could be used in economic evaluation-the EQ-5D-5L, ICECAP-A and ICECAP-O-in people requiring kidney care.
    Design: Participants were asked to 'think-aloud' while completing the EQ-5D-5L, ICECAP-A and ICECAP-O, followed by a semistructured interview. Five raters identified errors or struggles in completing the measures from the think-aloud component of the transcripts. Patient preferences for measures were extracted from the semistructured interview.
    Setting: Eligible patients were identified through a large UK secondary care renal centre.
    Participants: In total, 30 participants were included in the study, consisting of patients attending renal outpatients for chronic kidney disease (n=18), with a functioning kidney transplant (n=6) and receiving haemodialysis (n=6).
    Results: Participants had few errors and struggles in completing the EQ-5D-5L (11% error rate, 3% struggle rate), ICECAP-A (2% error rate, 2% struggle rate) and ICECAP-O (4% error rate, 3% struggle rate). The main errors with the EQ-5D-5L were judgements that did not comply with the 'your health today' instruction. Comprehension errors were most prominent on ICECAP-O. Judgement errors were the only errors reported on ICECAP-A. Although the EQ-5D-5L had slightly more errors and struggles, it was the measure most preferred, with participants able to make a clearer link with EQ-5D-5L and their health condition.
    Conclusions: The EQ-5D-5L, ICECAP-A and ICECAP-O are feasible for people requiring kidney care to complete and can be included in studies conducting economic evaluations of kidney care interventions. Further research is required to assess how health (eg, EQ-5D) and capability (eg, ICECAP) measures can be included in an economic evaluation simultaneously, as well as what ICECAP measure(s) to include when patient groups straddle the age ranges for ICECAP-A (18 years and older) and ICECAP-O (65 years and older).
    MeSH term(s) Adolescent ; Female ; Humans ; Kidney ; Kidney Diseases ; Male ; Outpatients ; Patient Reported Outcome Measures ; Psychometrics ; Quality of Life ; Reproducibility of Results ; Surveys and Questionnaires
    Language English
    Publishing date 2020-05-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2019-034569
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Challenges in developing capability measures for children and young people for use in the economic evaluation of health and care interventions.

    Mitchell, Paul Mark / Husbands, Samantha / Byford, Sarah / Kinghorn, Philip / Bailey, Cara / Peters, Tim J / Coast, Joanna

    Health economics

    2021  Volume 30, Issue 9, Page(s) 1990–2003

    Abstract: Methods for measuring outcomes suitable for economic evaluations of health and care interventions have primarily focused on adults. The validity of such methods for children and young people is questionable in areas including the outcome domains measured ...

    Abstract Methods for measuring outcomes suitable for economic evaluations of health and care interventions have primarily focused on adults. The validity of such methods for children and young people is questionable in areas including the outcome domains measured and how they are measured and valued, with most existing measures narrowly focusing on health. Novel methods for assessing benefits beyond health by focusing on a person's capability have also concentrated on adults to date. This paper aims to set out the rationale for capability measures in children and young people. It argues for the need to expand the evaluative space beyond health functioning towards broader capabilities, with children and young people playing an integral role in capability measure development. Drawing from existing literature, specific challenges related to the identification, measurement, and valuation of capabilities in children and young people are also discussed. Finally, the practical implications for conducting economic evaluation when measuring and valuing capabilities at different stages across the life-course are illustrated. We develop an alternative framework based on conceiving capabilities as evolving across the life-course. This framework may also be helpful in thinking about how to model health outcomes across the life-course.
    MeSH term(s) Adolescent ; Child ; Cost-Benefit Analysis ; Humans ; Outcome Assessment, Health Care ; Quality of Life
    Language English
    Publishing date 2021-05-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1135838-5
    ISSN 1099-1050 ; 1057-9230
    ISSN (online) 1099-1050
    ISSN 1057-9230
    DOI 10.1002/hec.4363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3555: Show issues Location:
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  9. Article ; Online: Correction to: Are Quality-Adjusted Life Years a Good Proxy Measure of Individual Capabilities?

    Mitchell, Paul Mark / Venkatapuram, Sridhar / Richardson, Jeff / Iezzi, Angelo / Coast, Joanna

    PharmacoEconomics

    2019  Volume 37, Issue 7, Page(s) 969

    Abstract: Open Access This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0International License. ...

    Abstract Open Access This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0International License.
    Language English
    Publishing date 2019-03-09
    Publishing country New Zealand
    Document type Published Erratum
    ZDB-ID 1100273-6
    ISSN 1179-2027 ; 1170-7690
    ISSN (online) 1179-2027
    ISSN 1170-7690
    DOI 10.1007/s40273-018-00763-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3579: Show issues Location:
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  10. Article: Applications of the Capability Approach in the Health Field: A Literature Review.

    Mitchell, Paul Mark / Roberts, Tracy E / Barton, Pelham M / Coast, Joanna

    Social indicators research

    2016  Volume 133, Issue 1, Page(s) 345–371

    Abstract: The primary aims of this review are to document capability applications in the health field and to explore the objectives and decision-rules of studies measuring capability more broadly. Relevant studies are identified using a literature search strategy ... ...

    Abstract The primary aims of this review are to document capability applications in the health field and to explore the objectives and decision-rules of studies measuring capability more broadly. Relevant studies are identified using a literature search strategy known as "comprehensive pearl growing". All studies with a primary focus on health are assessed individually, whilst a summary narrative analysis of the full review examines the objectives of capability studies. Four distinct groups in the health field are identified in the review: (1) physical activity and diet; (2) patient empowerment; (3) multidimensional poverty and (4) assessments of health and social care interventions. Different approaches to applying mixed methods, selecting capability dimensions and weighting capabilities are found across studies. There is a noticeable non-reliance on health status as a sole indicator of capability in health. In terms of objectives of studies measuring capability, although there is a lack of consistency, an objective related to sufficiency of capabilities appeared most often in the studies found in this review. Even though one of the appeals of the capability perspective is its underspecified nature, this review highlights the challenge of finding a coherent alternative to more established approaches of evaluation.
    Language English
    Publishing date 2016-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018687-3
    ISSN 1573-0921 ; 0303-8300
    ISSN (online) 1573-0921
    ISSN 0303-8300
    DOI 10.1007/s11205-016-1356-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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