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  1. Article ; Online: [To the memory of the late Dr. Shintaro Takeda].

    Miyashita, Kazuhisa

    Nihon eiseigaku zasshi. Japanese journal of hygiene

    2022  Volume 77

    Language Japanese
    Publishing date 2022-03-24
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 604089-5
    ISSN 1882-6482 ; 0021-5082
    ISSN (online) 1882-6482
    ISSN 0021-5082
    DOI 10.1265/jjh.2022o1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: [Efforts to improve workplaces considering for older workers: A questionnaire survey focusing on company size in Wakayama Prefecture, Japan].

    Morioka, Ikuharu / Takeshita, Tatsuya / Miyashita, Kazuhisa / Fujiyoshi, Akira / Ikuta, Zentaro

    Sangyo eiseigaku zasshi = Journal of occupational health

    2023  Volume 65, Issue 6, Page(s) 355–365

    Abstract: Objectives: The "Guidelines for Ensuring the Safety and Health of Older Workers (hereafter referred to as "Guidelines")," formulated in 2021, require employers to implement measures that proactively prevent occupational accidents among older workers. ... ...

    Abstract Objectives: The "Guidelines for Ensuring the Safety and Health of Older Workers (hereafter referred to as "Guidelines")," formulated in 2021, require employers to implement measures that proactively prevent occupational accidents among older workers. This study aimed to clarify the status of awareness of the Guidelines and workplace improvement efforts with consideration of older workers, focusing on company size.
    Methods: Overall, 780 businesses in Wakayama Prefecture, Japan, were randomly selected from a Wakayama Occupational Health Support Center workplace list. Anonymous self-administered questionnaires were distributed by mail. The questionnaires comprised questions about the workplace, status of awareness of the Guidelines, comprehensive management of safety and health, considerations for working conditions, workers, workload reduction, work posture, work environment, and safety and health.
    Results: One hundred and seventy-one businesses (effective response rate: 21.9%) provided questionnaires with complete responses. For the Guidelines, 39.0% of small-sized (less than 50 employees) businesses answered, "never even heard of the name," while many medium-sized (50-99 employees) and large-sized (100 or more employees) businesses answered that they had heard of the name but did not exactly know about it (33.3% of medium-sized businesses and 47.8% of large-sized businesses). Regarding the system that subsidizes the expenses required for the improvement of a working environment for older workers to work safely and securely (hereinafter referred to as the subsidy system), many businesses of all sizes answered that they had "never even heard of the name." In the comprehensive management of safety and health, half of the businesses of all sizes had developed a system that made it easy to consult about the risk against occupational accidents of older workers. Regardless of size, more than half of businesses were able to consider working conditions and workers. However, there were only a few items where more than half of the businesses considered workload reduction, work posture, work environment, and safety and health, regardless of business size. It became clear that workplace improvement had not progressed very much.
    Conclusions: These results suggest that to promote workplace improvement that considers older workers, it is necessary to disseminate the Guidelines and proactively take on workplace improvement by utilizing the subsidy system.
    MeSH term(s) Humans ; Japan ; Workplace ; Occupational Health ; Working Conditions ; Surveys and Questionnaires
    Language Japanese
    Publishing date 2023-06-23
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 1234922-7
    ISSN 1349-533X ; 1341-0725
    ISSN (online) 1349-533X
    ISSN 1341-0725
    DOI 10.1539/sangyoeisei.2023-002-E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Spot urinary sodium-to-potassium ratio is associated with blood pressure levels in healthy adolescents: the Wakayama Study.

    Zhang, Yan / Miyai, Nobuyuki / Utsumi, Miyoko / Miyashita, Kazuhisa / Arita, Mikio

    Journal of human hypertension

    2023  Volume 38, Issue 3, Page(s) 238–244

    Abstract: The spot urinary sodium-to-potassium (Na/K) ratio is a simple measure of salt loading and has been shown to be associated with elevated blood pressure (BP) in middle-aged and older adults. This study aimed to evaluate the association between the spot ... ...

    Abstract The spot urinary sodium-to-potassium (Na/K) ratio is a simple measure of salt loading and has been shown to be associated with elevated blood pressure (BP) in middle-aged and older adults. This study aimed to evaluate the association between the spot urinary Na/K ratio and BP in 457 healthy adolescents aged 12-15 years in a school-based setting. The mean urinary Na/K ratio was 4.99 ± 2.76, and no significant difference was found between the boys and girls. When the participants were stratified based on urinary Na/K ratio quartile, age- and sex-adjusted systolic and diastolic BP gradually increased as Na/K ratio increased (systolic BP: 106.1, 106.9, 108.2, and 111.5 mmHg, P
    MeSH term(s) Male ; Female ; Middle Aged ; Humans ; Adolescent ; Aged ; Blood Pressure/physiology ; Sodium Chloride, Dietary/adverse effects ; Hypertension/diagnosis ; Hypertension/epidemiology ; Sodium/urine ; Sodium Chloride ; Potassium/urine
    Chemical Substances Sodium Chloride, Dietary ; Sodium (9NEZ333N27) ; Sodium Chloride (451W47IQ8X) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-023-00883-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Workplace Bullying and Psychological Distress: A Longitudinal Multilevel Analysis Among Japanese Employees.

    Tsuno, Kanami / Kawachi, Ichiro / Kawakami, Norito / Miyashita, Kazuhisa

    Journal of occupational and environmental medicine

    2018  Volume 60, Issue 12, Page(s) 1067–1072

    Abstract: Objective: We sought to investigate the contextual effect of workplace bullying on subsequent individual psychological distress and intention to leave.: Methods: A longitudinal study was conducted among 3142 Japanese employees in the public sector. ... ...

    Abstract Objective: We sought to investigate the contextual effect of workplace bullying on subsequent individual psychological distress and intention to leave.
    Methods: A longitudinal study was conducted among 3142 Japanese employees in the public sector. Both the baseline and follow-up questionnaires inquired about demographic and occupational characteristics, workplace bullying, psychological distress, and intention to leave.
    Results: The results of three-level (individual-division-department) multilevel analyses revealed that division-level workplace bullying was associated with increased individual-level psychological distress after adjustment for individual experience of workplace bullying, while the association between individual experience of bullying and psychological distress was not statistically significant in the same model.
    Conclusion: The results of the current study suggest that the presence of bullying in the workplace can have a detrimental effect on employees' mental health even if they are not personally victimized.
    MeSH term(s) Adolescent ; Adult ; Aged ; Bullying/psychology ; Exposure to Violence/psychology ; Female ; Humans ; Intention ; Japan ; Longitudinal Studies ; Male ; Middle Aged ; Personnel Turnover ; Prospective Studies ; Public Sector/organization & administration ; Stress, Psychological/etiology ; Surveys and Questionnaires ; Workplace Violence/psychology ; Young Adult
    Language English
    Publishing date 2018-08-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1223932-x
    ISSN 1536-5948 ; 1076-2752
    ISSN (online) 1536-5948
    ISSN 1076-2752
    DOI 10.1097/JOM.0000000000001433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: [Support for a balance between work schedules and treatment regimens among workers with illness: A questionnaire survey focusing on company size in Wakayama Prefecture, Japan].

    Morioka, Ikuharu / Terashita, Hiroaki / Miyashita, Kazuhisa / Ikuta, Zentaro / Takeshita, Tatsuya / Fujiyoshi, Akira / Yamamoto, Norio / Yukami, Hitomi

    Sangyo eiseigaku zasshi = Journal of occupational health

    2022  Volume 65, Issue 1, Page(s) 28–40

    Abstract: Objectives: The support from businesses to create a balance between work schedules and treatment regimens among employees suffering from illnesses, such as cancer and diabetes, seems to be insufficient. This study aimed to investigate efforts of ... ...

    Abstract Objectives: The support from businesses to create a balance between work schedules and treatment regimens among employees suffering from illnesses, such as cancer and diabetes, seems to be insufficient. This study aimed to investigate efforts of businesses to support the balance of work schedules and treatment regimens among employees with illness, focusing on company size and to identify potential workplace improvements for such employees.
    Methods: Overall, 789 businesses in Wakayama Prefecture, Japan were randomly selected from a workplace list of the Wakayama Occupational Health Support Center. Anonymous questionnaires were distributed by mail. The questionnaires consisted of question items on workplace, current employees who had suffered or were suffering from cancer (employees with cancer), employees with illnesses (diseases such as cancer and diabetes), and support for businesses and employees.
    Results: Questionnaires with complete responses were collected from 187 businesses (response rate: 23.7%). The ratios of businesses where employees with cancer were engaged or had been engaged were 43.4% for small-sized (less than 50 employees), 70.9% for medium-sized (50-99 employees), and 83.1% for large-sized (100 and more employees) businesses. In all business sizes, the most common support in reinstatement or hiring employees with cancer was "absenteeism for treatment." The most common difficulty that occurred in the workplace due to the presence of employees with cancer was "the insufficient number of workers." The information from the attending physician, etc. necessary for deciding the reinstatement was mostly "the current health condition and physical strength." Additionally, in all business sizes, the most common support for employees with illness to balance work schedule and treatment regimens was "considering measures suitable to the situation such as hospital visits and physical condition." The most common challenge was "securing alternative personnel." The information from the attending physician, etc. necessary for deciding the reinstatement was "the current health condition and physical strength," similar to that for employees with cancer. More than 60% of the businesses of varying sizes reported being unaware of the work-treatment balance support coordinator.
    Conclusions: Considering measures suitable to the situation, such as hospital visits and physical condition, securing alternative personnel, and actively disseminating information regarding work-treatment balance support coordinators are recommended as workplace improvements for employees with illnesses.
    MeSH term(s) Humans ; Japan ; Neoplasms/therapy ; Occupational Health ; Personnel Staffing and Scheduling ; Surveys and Questionnaires ; Workplace
    Language Japanese
    Publishing date 2022-03-19
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 1234922-7
    ISSN 1349-533X ; 1341-0725
    ISSN (online) 1349-533X
    ISSN 1341-0725
    DOI 10.1539/sangyoeisei.2021-051-E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exaggerated blood pressure response to exercise is associated with subclinical vascular impairment in healthy normotensive individuals.

    Miyai, Nobuyuki / Shiozaki, Maki / Terada, Kazufumi / Takeshita, Tatsuya / Utsumi, Miyoko / Miyashita, Kazuhisa / Arita, Mikio

    Clinical and experimental hypertension (New York, N.Y. : 1993)

    2020  Volume 43, Issue 1, Page(s) 56–62

    Abstract: Background: This study was designed to evaluate the possible association between an exaggerated blood pressure (BP) response to exercise and subclinical vascular impairment in normotensive individuals.: Methods: The study participants consisted of 92 ...

    Abstract Background: This study was designed to evaluate the possible association between an exaggerated blood pressure (BP) response to exercise and subclinical vascular impairment in normotensive individuals.
    Methods: The study participants consisted of 92 untreated normotensive men (aged 42 ± 9 years) without a history of cardiovascular disease or stroke. A graded exercise test was conducted using a bicycle ergometer, and the mean arterial pressure (MAP) during submaximal exercise was evaluated. The brachial-ankle pulse wave velocity (baPWV) was measured as an index of arterial stiffness. The second peak of radial systolic BP (SBP2) was used as an estimate of central BP. The albumin-to-creatinine ratio (ACR) values were determined as the mean of two nonconsecutive spot urine specimens.
    Results: Compared with individuals with a normal response (MAP z-score < +1.0,
    Conclusions: These results suggest that subclinical vascular impairment is associated with an exaggerated increase in BP during exercise even in the absence of clinical hypertension.
    MeSH term(s) Adult ; Albuminuria/urine ; Ankle Brachial Index ; Arterial Pressure ; Asymptomatic Diseases ; Creatinine/urine ; Exercise/physiology ; Exercise Test ; Humans ; Male ; Middle Aged ; Pulse Wave Analysis ; Systole ; Vascular Diseases/physiopathology ; Vascular Diseases/urine ; Vascular Stiffness/physiology
    Chemical Substances Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2020-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 604757-9
    ISSN 1525-6006 ; 0730-0077
    ISSN (online) 1525-6006
    ISSN 0730-0077
    DOI 10.1080/10641963.2020.1806292
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Potential hypotensive effects of Umezu polyphenols: a 14-week community-based, double-masked and placebo-controlled trial.

    Takemura, Shigeki / Yoshimasu, Kouichi / Tsuno, Kanami / Kuroda, Mototsugu / Kishida, Kunihiro / Mitani, Takahiko / Miyashita, Kazuhisa

    Blood pressure monitoring

    2020  Volume 25, Issue 6, Page(s) 355–358

    Abstract: Objective: To evaluate blood pressure (BP)-lowering effects of Umezu polyphenols, polyphenols contained in Japanese plums, in a community-based sample by double-masked and placebo-controlled design.: Methods: Seventy-two Japanese community-dwellers ... ...

    Abstract Objective: To evaluate blood pressure (BP)-lowering effects of Umezu polyphenols, polyphenols contained in Japanese plums, in a community-based sample by double-masked and placebo-controlled design.
    Methods: Seventy-two Japanese community-dwellers who were interested in prevention or control of their BP (preferably high-normal BP or grade I hypertension) but without antihypertensive medication were randomized into Umezu polyphenols or placebo groups. Each subject took 800 mg/day of Umezu polyphenols or placebo for 12 weeks, followed by a 2-week washout period. Their home and office BP were monitored for 14 weeks in a double-masked manner. We analyzed 56 subjects who met the inclusion criteria.
    Results: Home BP increased gradually in both the groups during the intervention period, while diastolic office BP insignificantly decreased in the intervention group. During the washout period, home systolic BP in the morning elevated only in the intervention group.
    Conclusions: The study failed to collect consistent evidence of a clear persistent hypotensive effect of Umezu polyphenols.
    MeSH term(s) Acetic Acid/therapeutic use ; Antihypertensive Agents/therapeutic use ; Blood Pressure/drug effects ; Blood Pressure Determination ; Double-Blind Method ; Humans ; Hypertension/diet therapy ; Polyphenols/pharmacology ; Polyphenols/therapeutic use ; Prunus domestica
    Chemical Substances Antihypertensive Agents ; Polyphenols ; Acetic Acid (Q40Q9N063P)
    Language English
    Publishing date 2020-09-15
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1324472-3
    ISSN 1473-5725 ; 1359-5237
    ISSN (online) 1473-5725
    ISSN 1359-5237
    DOI 10.1097/MBP.0000000000000476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Human exposure to phthalates from house dust in Bangkok, Thailand

    Promtes, Kamonwan / Kaewboonchoo, Orawan / Kawai, Toshio / Kwonpongsagoon, Suphaphat / Miyashita, Kazuhisa / Panyapinyopol, Bunyarit / Takemura, Shigeki

    Journal of environmental science and health. 2019 Nov. 10, v. 54, no. 13

    2019  

    Abstract: The study determined concentrations of and estimated human exposure to house dust-ingested phthalates from 99 homes in Bangkok, Thailand. Phthalates in dust collected using a handheld vacuum cleaner was analyzed by gas chromatography/mass spectrometry ... ...

    Abstract The study determined concentrations of and estimated human exposure to house dust-ingested phthalates from 99 homes in Bangkok, Thailand. Phthalates in dust collected using a handheld vacuum cleaner was analyzed by gas chromatography/mass spectrometry revealing a median content of 3,477 μg g−1, range 753–13,810 μg g−1, with di-2-ethylhexylphthalate (DEHP) having the highest level (median = 1,739 μg g−1, range 467–8,172 μg g−1) followed by di-iso-nonyl phthalate (DiNP) (median = 611 μg g−1, range 15.2–11,052 μg g−1). DEHP in house dust from multi-family apartments with polyvinyl (PVC) floor material (n = 34), multi-family apartments without PVC floor material (n = 55) and single family houses without PVC floor material (n = 10) was median and range 3,009 and 568–6,898; 1,479 and range 467–8,172 and 1,207 μg g−1 and 611–3518 μg g−1, respectively. At high-end house dust DEHP level, preschool children in all three types of homes were exposed above US Environment Protection Agency reference dose (20 μg g−1). The results suggest phthalate-containing house products constitute a likely major source of phthalates in indoor home environment and pose a potential health risk to residents, particularly preschool children, in Bangkok.
    Keywords dust ; gas chromatography-mass spectrometry ; humans ; phthalates ; poly(vinyl chloride) ; preschool children ; residential housing ; risk ; vacuum cleaners ; Thailand
    Language English
    Dates of publication 2019-1110
    Size p. 1269-1276.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 196584-0
    ISSN 1532-4117 ; 0360-1226 ; 1077-1204 ; 1093-4529
    ISSN (online) 1532-4117
    ISSN 0360-1226 ; 1077-1204 ; 1093-4529
    DOI 10.1080/10934529.2019.1637207
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Brachial-ankle pulse wave velocity in healthy Japanese adolescents: reference values for the assessment of arterial stiffness and cardiovascular risk profiles.

    Sougawa, Yukiko / Miyai, Nobuyuki / Utsumi, Miyoko / Miyashita, Kazuhisa / Takeda, Shintaro / Arita, Mikio

    Hypertension research : official journal of the Japanese Society of Hypertension

    2019  Volume 43, Issue 4, Page(s) 331–341

    Abstract: Brachial-ankle pulse wave velocity (baPWV) has been used as a simple and convenient method of evaluating arterial stiffness and is considered useful for screening subclinical vascular damage in primary care settings and in large populations. The aim of ... ...

    Abstract Brachial-ankle pulse wave velocity (baPWV) has been used as a simple and convenient method of evaluating arterial stiffness and is considered useful for screening subclinical vascular damage in primary care settings and in large populations. The aim of this study was to determine the reference values of baPWV in adolescents based on age and sex to evaluate and classify vascular abnormalities in this age population. Noninvasive baPWV measurements using an oscillometric device were carried out in 5936 participants aged 12-18 years who had no history of syndromic obesity, hypertension, dyslipidemia, diabetes mellitus, or renal disease. Of these, we extracted data from 4524 healthy adolescents free from atherosclerotic risk factors and constructed sex-specific reference percentiles normalized to age using the LMS method. The baPWV increased with age and was significantly higher in males than in females. Multivariate regression analysis demonstrated that age, body mass index, and blood pressure were the major determinants of baPWV for both males and females. Among a sample of 3825 adolescents, including individuals with risk factors, the prevalence of central obesity, raised blood pressure, raised triglycerides, reduced high-density lipoprotein cholesterol, and impaired fasting glycemia significantly increased along with the standardized baPWV z-score level. In addition, there was a graded nature regarding the association between the baPWV z-score and the clustering number of the metabolic syndrome components. These results suggest that the proposed reference values of baPWV could help classify vascular abnormalities of adolescents caused by the presence of risk factors and thereby contribute to determining individuals with cardiovascular risk in this age population.
    MeSH term(s) Adolescent ; Ankle Brachial Index ; Blood Pressure/physiology ; Brachial Artery/physiology ; Child ; Female ; Heart Disease Risk Factors ; Humans ; Japan ; Male ; Pulse Wave Analysis ; Reference Values ; Vascular Stiffness/physiology
    Language English
    Publishing date 2019-12-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1175297-x
    ISSN 1348-4214 ; 0916-9636
    ISSN (online) 1348-4214
    ISSN 0916-9636
    DOI 10.1038/s41440-019-0370-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: [Supporting a balance between work schedules and treatment regimens among cancer patients: A questionnaire survey focusing on company size in Wakayama Prefecture, Japan].

    Morioka, Ikuharu / Terashita, Hiroaki / Miyashita, Kazuhisa / Ikuta, Zentaro / Takeshita, Tatsuya / Taoda, Kazushi

    Sangyo eiseigaku zasshi = Journal of occupational health

    2019  Volume 61, Issue 5, Page(s) 159–169

    Abstract: Objectives: The support from businesses to create a balance between work schedules and treatment regimens among employees suffering from cancer seems to be insufficient. The aims of this study were to investigate efforts to find a balance between work ... ...

    Abstract Objectives: The support from businesses to create a balance between work schedules and treatment regimens among employees suffering from cancer seems to be insufficient. The aims of this study were to investigate efforts to find a balance between work schedules and treatment regimens among cancer patients focusing on company size and to identify potential workplace improvements for these employees.
    Methods: Seven hundred and seventy businesses in Wakayama Prefecture, Japan, were randomly selected from a workplace list consisting of businesses that had received support from either the Wakayama Occupational Health Support Center or the Regional Occupational Health Center. An anonymous questionnaire was distributed by mail. It consisted of question items on the workplace, support systems, current employees who had suffered or were suffering from cancer (cancer patient employees), their reinstatement, promoting reinstatement and employment of cancer patient employees, and job description of respondents.
    Results: A completed questionnaire was collected from 188 businesses (response rate: 24.4%). Among small-sized businesses (less than 50 employees), 55% carried out or recommended consultation for cancer screening. This ratio was higher than that of medium-sized businesses (50-99 employees) or large-sized businesses (100 or more employees). Approximately 20% of the businesses had a support system for employees who were working while undergoing cancer treatment, and more small-sized businesses had a system of annual paid leave by the hour than the medium-sized or large-sized businesses. Among the small-sized businesses, 51% had a system of sick leave for regular employees, but this ratio was significantly lower than that among the large-sized businesses. Approximately 20% of businesses had established a system of paid sick leave for regular employees. Reinstatement of employment was possible in over 80% of the businesses. The condition for reinstatement that was most frequently stipulated was that the employee's doctor had provided a medical certificate stating that the employee was able to return to work. However, among small-sized businesses, the condition that colleagues at the workplace were willing to accept him/her was more frequently stipulated.
    Conclusions: Cancer screening, annual paid leave by the hour, and institutionalization of sick leave are recommended as workplace improvements for cancer patient employees.
    MeSH term(s) Employment ; Humans ; Japan ; Neoplasms/psychology ; Neoplasms/therapy ; Occupational Health ; Personnel Staffing and Scheduling ; Return to Work ; Sick Leave ; Social Support ; Surveys and Questionnaires ; Workplace
    Language Japanese
    Publishing date 2019-04-27
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1234922-7
    ISSN 1349-533X ; 1341-0725
    ISSN (online) 1349-533X
    ISSN 1341-0725
    DOI 10.1539/sangyoeisei.2018-036-E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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