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  1. Article ; Online: Factors associated with cancer disclosure in adolescent and young adult cancer survivors: An integrative review from the social-ecological model perspective.

    Honda, Naoko / Shiroshita, Yui / Miyazaki, Asuka / Sobue, Ikuko

    European journal of oncology nursing : the official journal of European Oncology Nursing Society

    2024  Volume 69, Page(s) 102542

    Abstract: Purpose: Young cancer survivors ("young survivors") may need to disclose their cancer experiences to reintegrate into society. In such cases, the recognition of social support through the disclosure of cancer experiences may prevent potential social ... ...

    Abstract Purpose: Young cancer survivors ("young survivors") may need to disclose their cancer experiences to reintegrate into society. In such cases, the recognition of social support through the disclosure of cancer experiences may prevent potential social disadvantages. This review aimed to describe the motivations, strategies and outcomes, and benefits and disadvantages of disclosure in young survivors based on the social-ecological model (SEM) to identify the support survivors need when disclosing their cancer experiences.
    Methods: Using the integrated review methodology, we systematically searched six databases in English and Japanese as well as searched the reference lists of the selected studies. The themes identified via thematic analysis were categorized within the SEM levels.
    Results: This review analyzed 14 studies and identified four themes, including "Motivation for Cancer Disclosure," "Barriers to Cancer Disclosure," "Consequences of Cancer Disclosure: Benefits," and "Consequences of Cancer Disclosure: Disadvantages." Motivations for young survivors to disclose their cancer involved post-cancer differences, perceptions, relationships, and social context. In navigating barriers, including self-stigma, peer exclusion, and discrimination, they employed strategies such as reassurance and information limitation. Tailored disclosure strategies at each SEM level offered social and psychological benefits, however, disadvantages, including stress, vulnerability, employment issues, and limited insurance coverage, were experienced by young survivors due to cancer disclosure.
    Conclusions: To optimize the benefits of cancer disclosure for young survivors, addressing psychological burdens, enhancing disclosure skills, offering familial psychological support, and fostering public awareness of cancer are essential.
    MeSH term(s) Humans ; Young Adult ; Adolescent ; Disclosure ; Cancer Survivors/psychology ; Survivors ; Social Stigma ; Social Support ; Neoplasms/psychology
    Language English
    Publishing date 2024-02-23
    Publishing country Scotland
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2017117-1
    ISSN 1532-2122 ; 1462-3889
    ISSN (online) 1532-2122
    ISSN 1462-3889
    DOI 10.1016/j.ejon.2024.102542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Determination of optimal 25-hydroxyvitamin D cutoff values for the evaluation of restless legs syndrome among pregnant women.

    Miyazaki, Asuka / Takahashi, Misako / Shuo, Takuya / Eto, Hiromi / Kondo, Hideaki

    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    2022  Volume 19, Issue 1, Page(s) 73–83

    Abstract: Study objectives: Vitamin D deficiency is associated with restless legs syndrome (RLS). However, a cutoff value for serum 25-hydroxyvitamin D (25[OH]D) level associated with RLS has yet to be clearly determined. We evaluated the association between 25( ... ...

    Abstract Study objectives: Vitamin D deficiency is associated with restless legs syndrome (RLS). However, a cutoff value for serum 25-hydroxyvitamin D (25[OH]D) level associated with RLS has yet to be clearly determined. We evaluated the association between 25(OH)D and RLS in pregnant women.
    Methods: Data from 203 pregnant women were evaluated using blood samples taken in the third trimester. Liquid chromatography-tandem mass spectrometry and ligand binding assays were used to measure 25(OH)D. RLS was diagnosed based on
    Results: The results of liquid chromatography-tandem mass spectrometry (
    Conclusions: Vitamin D and folate deficiency were associated with RLS in pregnant women and may be associated with persistent moderate-to-severe postpartum RLS symptomatology; it is essential to examine associations with RLS while accounting for measurement methods and assay systems.
    Citation: Miyazaki A, Takahashi M, Shuo T, Eto H, Kondo H. Determination of optimal 25-hydroxyvitamin D cutoff values for the evaluation of restless legs syndrome among pregnant women.
    MeSH term(s) Pregnancy ; Female ; Humans ; Pregnant Women ; Restless Legs Syndrome/complications ; Ligands ; Vitamin D ; Folic Acid
    Chemical Substances 25-hydroxyvitamin D (A288AR3C9H) ; Ligands ; Vitamin D (1406-16-2) ; Folic Acid (935E97BOY8)
    Language English
    Publishing date 2022-08-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2397213-0
    ISSN 1550-9397 ; 1550-9389
    ISSN (online) 1550-9397
    ISSN 1550-9389
    DOI 10.5664/jcsm.10270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Frequent unregulated use of antibiotics in rural Cambodian infants.

    Miyazaki, Asuka / Tung, Rathavy / Taing, Bunsreng / Matsui, Mitsuaki / Iwamoto, Azusa / Cox, Sharon E

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2020  Volume 114, Issue 6, Page(s) 401–407

    Abstract: Background: Despite a high prevalence of antibiotic resistance in Cambodia, few studies have assessed health-seeking behaviour and the use of antibiotics by caregivers of young children in Cambodia.: Methods: We conducted a cross-sectional survey of ... ...

    Abstract Background: Despite a high prevalence of antibiotic resistance in Cambodia, few studies have assessed health-seeking behaviour and the use of antibiotics by caregivers of young children in Cambodia.
    Methods: We conducted a cross-sectional survey of infants <12 months of age and their caregivers, assessing the frequency of reported illness, common symptoms and associated health-seeking behaviour through structured questionnaires administered by trained fieldworkers at a home visit. In a subset of these participants, ages 4-8 months with no acute malnutrition, we conducted a 3-month surveillance with fortnightly home visits.
    Results: Of 149 infants (ages 1-11 months, 54.4% male) enrolled in the cross-sectional study, 76 (51.4%) reported symptoms of diarrhoea, fever or cough in the previous 14 d, with associated use of antibiotics reported in 22 (14.8%) infants. In 47 infants enrolled in the longitudinal surveillance, there were 141 reported episodes of illness in 44 (94%) infants with 21 infants (45%) reported to have received antibiotics in 32/141 (22.7%) episodes. Amoxicillin was the most commonly reported antibiotic in both surveys (68% [40/59 episodes reporting the use of antibiotics]).
    Conclusions: Antibiotic usage is high in this population and appears to be occurring largely outside of the formal healthcare system.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Asian Continental Ancestry Group ; Cambodia/epidemiology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Infant ; Male ; Rural Population
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2020-04-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/traa020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Endogenous oxytocin levels in extracted saliva elevates during breastfeeding correlated with lower postpartum anxiety in primiparous mothers.

    Nagahashi-Araki, Miyuki / Tasaka, Makoto / Takamura, Tsunehiko / Eto, Hiromi / Sasaki, Noriko / Fujita, Wakako / Miyazaki, Asuka / Morifuji, Kanako / Honda, Naoko / Miyamura, Tunetake / Nishitani, Shota

    BMC pregnancy and childbirth

    2022  Volume 22, Issue 1, Page(s) 711

    Abstract: Background: Breastfeeding in the early postpartum period is expected to have mental benefits for mothers; however, the underlying psychobiological mechanisms remain unclear. Previously, we hypothesized that the release of oxytocin in response to the ... ...

    Abstract Background: Breastfeeding in the early postpartum period is expected to have mental benefits for mothers; however, the underlying psychobiological mechanisms remain unclear. Previously, we hypothesized that the release of oxytocin in response to the suckling stimuli during breastfeeding would mediate a calming effect on primiparous mothers, and we examined salivary oxytocin measurements in primiparous mothers at postpartum day 4 using saliva samples without extraction, which was erroneous. Thus, further confirmation of this hypothesis with a precise methodology was needed.
    Methods: We collected saliva samples at three time points (baseline, feeding, and post-feeding) to measure oxytocin in 24 primiparous mothers on postpartum day 2 (PD2) and 4 (PD4) across the breastfeeding cycle. Salivary oxytocin levels using both extracted and unextracted methods were measured and compared to determine the qualitative differences. State and trait anxiety and clinical demographics were evaluated to determine their association with oxytocin changes.
    Results: Breastfeeding elevated salivary oxytocin levels; however, it was not detected to a significant increase in the extraction method at PD4. We found a weak but significant positive correlation between changes in extracted and unextracted oxytocin levels during breastfeeding (feeding minus baseline); there were no other significant positive correlations. Therefore, we used the extracted measurement index for subsequent analysis. We showed that the greater the increase in oxytocin during breastfeeding, the lower the state anxiety, but not trait anxiety. Mothers who exclusively breastfed at the 1-month follow-up tended to be associated with slightly higher oxytocin change at PD2 than those who did not.
    Conclusions: Breastfeeding in early postpartum days could be accompanied by the frequent release of oxytocin and lower state anxiety, potentially contributing to exclusive breastfeeding.
    MeSH term(s) Anxiety/metabolism ; Breast Feeding/psychology ; Female ; Humans ; Oxytocin/analysis ; Oxytocin/metabolism ; Postpartum Period/metabolism ; Postpartum Period/psychology ; Saliva/chemistry ; Saliva/metabolism
    Chemical Substances Oxytocin (50-56-6)
    Language English
    Publishing date 2022-09-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059869-5
    ISSN 1471-2393 ; 1471-2393
    ISSN (online) 1471-2393
    ISSN 1471-2393
    DOI 10.1186/s12884-022-05026-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Determinants of growth measurements in rural Cambodian infants: a cross-sectional study.

    Miyazaki, Asuka / Matsui, Mitsuaki / Tung, Rathavy / Taing, Bunsreng / White, Laura V / Iwamoto, Azusa / Cox, Sharon E

    International health

    2020  Volume 13, Issue 1, Page(s) 49–56

    Abstract: Background: Inappropriate feeding and hygiene practices and poor environment are associated with malnutrition. We aimed to investigate the contributions of feeding, hygiene practices and recent illness to the nutritional status of rural Cambodian ... ...

    Abstract Background: Inappropriate feeding and hygiene practices and poor environment are associated with malnutrition. We aimed to investigate the contributions of feeding, hygiene practices and recent illness to the nutritional status of rural Cambodian infants and any sex-specific differences.
    Methods: In a cross-sectional study, nested within an ongoing birth cohort, trained fieldworkers conducted anthropometry and collected information from the main caregiver during home visits. Multivariable linear regression was used to investigate associations with nutritional status as length-for-age z-scores (LAZ) and weight-for-length z-scores (WLZ).
    Results: A total of 156 children, 87 (55.8%) male, ages 0-11 months were enrolled. The prevalence of acute malnutrition (WLZ <-2) in males and females was 2.3% (2/87) and 5.8% (4/69), respectively, and 23.0% (20/87) of males and 14.5% (10/69) of females were stunted (LAZ <-2). WLZ but not LAZ decreased with age. WLZ was independently negatively associated with increasing age (β-coefficient -0.14 [95% confidence interval {CI} -0.20 to -0.08], p<0.001), and regular use of feeding bottles (β-coefficient -0.46 [95% CI -0.83 to -0.10], p=0.014), and positively with handwashing with soap (β-coefficient 0.40 [95% CI 0.05 to 0.75), p=0.027).
    Conclusions: The prevalence of acute malnutrition was low, but stunting was prevalent without evidence of a sex difference. Non-linear growth faltering was associated with increasing age and hygiene/feeding practices.
    Language English
    Publishing date 2020-05-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2526175-7
    ISSN 1876-3405 ; 1876-3413
    ISSN (online) 1876-3405
    ISSN 1876-3413
    DOI 10.1093/inthealth/ihaa018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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