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  1. Article: Acute portal vein thrombosis with COVID-19 and cirrhosis.

    Miyazato, Yusuke / Ishikane, Masahiro / Inada, Makoto / Ohmagari, Norio

    IDCases

    2021  Volume 24, Page(s) e01094

    Language English
    Publishing date 2021-03-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2021.e01094
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  2. Article ; Online: Severe Inflammatory Response in Myelodysplastic Syndrome and Trisomy 8 Following 23-valent Polysaccharide Pneumococcal Vaccine Administration.

    Fujikawa, Hirohisa / Miyazato, Yusuke / Ebisuda, Kenichiro / Saito, Minoru

    Turkish journal of haematology : official journal of Turkish Society of Haematology

    2021  

    Language English
    Publishing date 2021-01-06
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2185903-6
    ISSN 1308-5263 ; 1300-7777
    ISSN (online) 1308-5263
    ISSN 1300-7777
    DOI 10.4274/tjh.galenos.2020.2020.0664
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Severe Inflammatory Response in Myelodysplastic Syndrome and Trisomy 8 Following 23-Valent Polysaccharide Pneumococcal Vaccine Administration.

    Fujikawa, Hirohisa / Miyazato, Yusuke / Ebisuda, Kenichiro / Saito, Minoru

    Turkish journal of haematology : official journal of Turkish Society of Haematology

    2021  Volume 38, Issue 1, Page(s) 92–94

    Language English
    Publishing date 2021-02-26
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2185903-6
    ISSN 1308-5263 ; 1300-7777
    ISSN (online) 1308-5263
    ISSN 1300-7777
    DOI 10.4274/tjh.galenos.2021.2020.0664
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  4. Article ; Online: A nationwide prospective cohort study on safety of the 17D-204 yellow fever vaccine during a vaccine shortage in Japan.

    Miyazato, Yusuke / Terada, Mari / Ujiie, Mugen / Saito, Sho / Moriya, Akinari / Ando, Masao / Ohmagari, Norio

    Journal of travel medicine

    2022  Volume 30, Issue 2

    MeSH term(s) Humans ; Yellow Fever Vaccine ; Prospective Studies ; Japan ; Yellow Fever/prevention & control ; Yellow fever virus ; Vaccines ; Antibodies, Viral
    Chemical Substances Yellow Fever Vaccine ; Vaccines ; Antibodies, Viral
    Language English
    Publishing date 2022-05-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taac070
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4120: Show issues Location:
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  5. Article ; Online: Impact of long-COVID on health-related quality of life in Japanese COVID-19 patients.

    Tsuzuki, Shinya / Miyazato, Yusuke / Terada, Mari / Morioka, Shinichiro / Ohmagari, Norio / Beutels, Philippe

    Health and quality of life outcomes

    2022  Volume 20, Issue 1, Page(s) 125

    Abstract: Background: The empirical basis for a quantitative assessment of the disease burden imposed by long-COVID is currently scant. We aimed to inform the disease burden caused by long-COVID in Japan.: Methods: We conducted a cross sectional self-report ... ...

    Abstract Background: The empirical basis for a quantitative assessment of the disease burden imposed by long-COVID is currently scant. We aimed to inform the disease burden caused by long-COVID in Japan.
    Methods: We conducted a cross sectional self-report questionnaire survey. The questionnaire was mailed to 526 eligible patients, who were recovered from acute COVID-19 in April 2021. Answers were classified into two groups; participants who have no symptom and those who have any ongoing prolonged symptoms that lasted longer than four weeks at the time of the survey. We estimated the average treatment effect (ATE) of ongoing prolonged symptoms on EQ-VAS and EQ-5D-3L questionnaire using inverse probability weighting. In addition to symptom prolongation, we investigated whether other factors (including demography, lifestyle, and acute severity) were associated with low EQ-VAS and EQ-5D-3L values, by multivariable linear regression.
    Results: 349 participants reported no symptoms and 108 reported any symptoms at the time of the survey. The participants who reported any symptoms showed a lower average value on the EQ-VAS (69.9 vs 82.8, respectively) and on the EQ-5D-3L (0.85 vs 0.96, respectively) than those reporting no symptoms considering the ATE of ongoing prolonged symptoms. The ATE of ongoing prolonged symptoms on EQ-VAS was - 12.9 [95% CI - 15.9 to - 9.8], and on the EQ-5D-3L it was - 0.11 [95% CI - 0.13 to - 0.09], implying prolonged symptoms have a negative impact on patients' EQ-VAS and EQ-5D-3L score. In multivariable linear regression, only having prolonged symptoms was associated with lower scores (- 11.7 [95% CI - 15.0 to - 8.5] for EQ-VAS and - 0.10 [95% CI - 0.13 to - 0.08] for EQ-5D-3L).
    Conclusions: Due to their long duration, long-COVID symptoms represent a substantial disease burden expressed in impact on health-related quality of life.
    MeSH term(s) COVID-19/complications ; Cross-Sectional Studies ; Health Status ; Humans ; Japan/epidemiology ; Quality of Life ; Surveys and Questionnaires
    Language English
    Publishing date 2022-08-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2098765-1
    ISSN 1477-7525 ; 1477-7525
    ISSN (online) 1477-7525
    ISSN 1477-7525
    DOI 10.1186/s12955-022-02033-6
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  6. Article ; Online: Association between SARS-CoV-2 anti-spike antibody titers and the development of post-COVID conditions: A retrospective observational study.

    Miyazato, Yusuke / Tsuzuki, Shinya / Matsunaga, Akihiro / Morioka, Shinichiro / Terada, Mari / Saito, Sho / Iwamoto, Noriko / Kutsuna, Satoshi / Ishizaka, Yukihito / Ohmagari, Norio

    Global health & medicine

    2022  Volume 5, Issue 2, Page(s) 106–111

    Abstract: The symptoms that persist after an acute coronavirus disease 2019 (COVID-19) are referred to as post- COVID conditions. Although the cause of post-COVID conditions remains unclear, the host immune response to SARS-CoV-2 may be involved. Hence, we aimed ... ...

    Abstract The symptoms that persist after an acute coronavirus disease 2019 (COVID-19) are referred to as post- COVID conditions. Although the cause of post-COVID conditions remains unclear, the host immune response to SARS-CoV-2 may be involved. Hence, we aimed to investigate the effect of serum antibody titers against SARS-CoV-2 on the development of post-COVID conditions. We conducted a retrospective observational study of COVID-19-recovered individuals who attended the clinic at the National Center for Global Health and Medicine between January 2020 and April 2021. Serum SARS-CoV-2 anti-spike antibody titers were measured and a questionnaire survey was used to collect information on the presence of post-COVID conditions and demographic characteristics of the participants. Participants were then divided into two groups: high peak antibody titer group [≥ 0.759 OD450 value], and low peak antibody titer group [< 0.759 OD450 value] and compared their frequency of post-COVID conditions. Of 526 individuals attending the clinic, 457 (86.9%) responded to the questionnaire. We analyzed the data of 227 (49.7%) participants with measurements of serum antibody titers during the peak period. The incidence of depressed mood was significantly higher in the group with higher antibody titers (odds ratio: 2.34, 95% CI: 1.17-4.67,
    Language English
    Publishing date 2022-11-15
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 3140544-7
    ISSN 2434-9194 ; 2434-9194 ; 2434-9186
    ISSN (online) 2434-9194
    ISSN 2434-9194 ; 2434-9186
    DOI 10.35772/ghm.2022.01070
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  7. Article ; Online: Chromosomal coharboring of bla

    Miyazato, Yusuke / Iwamoto, Noriko / Usui, Masaru / Sato, Toyotaka / Miyoshi-Akiyama, Tohru / Nagashima, Maki / Mezaki, Kazuhisa / Hayakawa, Kayoko / Ohmagari, Norio

    BMC infectious diseases

    2022  Volume 22, Issue 1, Page(s) 762

    Abstract: Background: Polymyxin E (colistin) is a last-resort antibiotic to treat infections caused by carbapenemase-producing Enterobacteriaceae (CPE). However, reports of CPEs resistant to colistin have been increasing, and the mcr genes are emerging as ... ...

    Abstract Background: Polymyxin E (colistin) is a last-resort antibiotic to treat infections caused by carbapenemase-producing Enterobacteriaceae (CPE). However, reports of CPEs resistant to colistin have been increasing, and the mcr genes are emerging as resistance mechanisms. Among them, plasmid-mediate mcr-9 is known to be associated with colistin resistance, whereas reports on chromosomal mcr-9 and its association with colistin resistance in humans are few.
    Case presentation: We identified Enterobacter asburiae harboring mcr-9 and bla
    Conclusion: Our case report showed that mcr-9 can be present not only on plasmids but also on the chromosome in E. asburiae, and that the presence of mcr-9 on its chromosome may influence its susceptibility to colistin.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Chromosomes ; Colistin/pharmacology ; Drug Resistance, Bacterial/genetics ; Empyema ; Enterobacter ; Escherichia coli Proteins/genetics ; Humans ; Inosine Monophosphate ; Japan ; Microbial Sensitivity Tests ; Plasmids
    Chemical Substances Anti-Bacterial Agents ; Escherichia coli Proteins ; Inosine Monophosphate (131-99-7) ; Colistin (Z67X93HJG1)
    Language English
    Publishing date 2022-09-30
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-022-07730-7
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  8. Article ; Online: Cerebral syphilitic Gumma in the modern era: a report of an unusual case and brief review of recent published reports.

    Kanayama, Seisaku / Nagata, Soudai / Akiyama, Yutaro / Miyazato, Yusuke / Ishikane, Masahiro / Inoue, Masato / Ohmagari, Norio / Hara, Tetsuo

    British journal of neurosurgery

    2022  , Page(s) 1–6

    Abstract: Background: Cerebral syphilitic gummas are rare. However, numerous case reports on them have been published recently, consistent with the resurgence of syphilis and its accompanying atypical manifestations. We here present a patient with a cerebral ... ...

    Abstract Background: Cerebral syphilitic gummas are rare. However, numerous case reports on them have been published recently, consistent with the resurgence of syphilis and its accompanying atypical manifestations. We here present a patient with a cerebral syphilitic gumma and an unusual clinical course and review recent case reports.
    Case presentation: A 49-year-old woman had a generalised seizure and was found by computed tomography and magnetic resonance imaging to have a brain mass that mimicked a brain abscess or malignant tumour. Further imaging with magnetic resonance spectroscopy and positron emission tomography did not contribute further to the differential diagnosis. Because treatment with ceftriaxone was ineffective, the lesion was resected. Serological tests on serum and cerebrospinal fluid were positive for syphilis and histopathological examination of the operative specimen revealed a syphilitic gumma. Antibiotic treatment is preferred over invasive interventions for cerebral syphilitic gumma. However, as in our case, radical resection is required when antibiotic treatment is ineffective.
    Conclusions: It has recently been reported that the prevalence of syphilis is increasing in older individuals, including in patients without HIV infection or prior treatment for early syphilis. Though advanced imaging and molecular biological techniques are often used to help make a diagnosis, they are of limited value. Because the clinical and imaging features are nonspecific, some neurosurgeons do not include cerebral syphilitic gummas in their differential diagnoses. It is vital that this possibility be considered when a patient has a tumour-like cerebral mass and serum positivity for syphilis.
    Language English
    Publishing date 2022-12-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639029-8
    ISSN 1360-046X ; 0268-8697
    ISSN (online) 1360-046X
    ISSN 0268-8697
    DOI 10.1080/02688697.2022.2159923
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    Zs.A 2210: Show issues Location:
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  9. Article ; Online: Clinical experience with high-flow nasal cannulas for coronavirus disease 2019 patients in Japan.

    Katsuno, Takashi / Suzuki, Manabu / Hojo, Masayuki / Terada, Junko / Nakamura, Keiji / Suzuki, Tetsuya / Miyazato, Yusuke / Sugiyama, Haruhito

    Respiratory investigation

    2021  Volume 59, Issue 4, Page(s) 569–572

    MeSH term(s) Aged ; COVID-19/therapy ; Cannula ; Cross Infection/prevention & control ; Female ; Humans ; Hyperbaric Oxygenation/methods ; Intubation, Intratracheal/statistics & numerical data ; Japan ; Male ; Middle Aged
    Language English
    Publishing date 2021-03-26
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2660821-2
    ISSN 2212-5353 ; 2212-5345
    ISSN (online) 2212-5353
    ISSN 2212-5345
    DOI 10.1016/j.resinv.2021.02.011
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  10. Article ; Online: Impact of long-COVID on health-related quality of life in Japanese COVID-19 patients

    Tsuzuki, Shinya / Miyazato, Yusuke / Terada, Mari / Morioka, Shinichiro / Ohmagari, Norio / Beutels, Philippe

    medRxiv

    Abstract: Background The empirical basis for a quantitative assessment of the disease burden imposed by long-COVID is currently scant. We aimed to assess the disease burden caused by long-COVID in Japan. Methods We conducted a cross sectional self-report ... ...

    Abstract Background The empirical basis for a quantitative assessment of the disease burden imposed by long-COVID is currently scant. We aimed to assess the disease burden caused by long-COVID in Japan. Methods We conducted a cross sectional self-report questionnaire survey. The questionnaire was mailed to 530 eligible patients, who were recovered from acute COVID-19 in April 2021. Answers were classified into two groups; participants who have no symptom and those who have any ongoing symptoms that lasted longer than four weeks at the time of the survey. We compared health-related quality of life scores estimated by the EQ5D-3L questionnaire between these two groups after adjusting basic characteristics of the participants by propensity score matching. Results 349 participants reported no symptoms and 108 reported any symptoms at the time of the survey. The participants who reported any symptoms showed a lower value on a Visual Analogue Scale (median 70 [IQR 60-80]) and on the EQ-5D-3L (median 0.81 [IQR 0.77-1.0]) than those reporting no symptoms (median 85 [IQR 75-90] and 1.0 [IQR 1.0-1.0], respectively). After adjusting for background characteristics, these trends did not change substantially (Visual Analog Scale: median 70 [IQR 60-80] vs 80 [IQR 77-90], EQ-5D-3L: median 0.81 [IQR 0.76-1.0] vs 1.0 [IQR 1.0-1.0]). Conclusions Due to their long duration, long-COVID symptoms represent a substantial disease burden expressed in impact on health-related quality of life.
    Keywords covid19
    Language English
    Publishing date 2021-09-29
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2021.09.27.21264225
    Database COVID19

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