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  1. Article ; Online: Facile Fabrication of a ZnO/Eu2O3/NiO-Based Ternary Heterostructure Nanophotocatalyst and Its Application for the Degradation of Methylene Blue

    J. Pranesh Shubha / Syed F. Adil / Mujeeb Khan / Mohammad R. Hatshan / Aslam Khan

    ACS Omega, Vol 6, Iss 5, Pp 3866-

    2021  Volume 3874

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Spectroscopic, anti-bacterial, anti-cancer and molecular docking of Pd(II) and Pt(II) complexes with (E)-4-((dimethylamino)methyl)-2-((4,5-dimethylthiazol-2-yl)diazenyl)phenol ligand

    Ahmed S.M. Al-Janabi / Khulood H. Oudah / Samar A. Aldossari / Mohamed A. Khalaf / Abdulrahman M. Saleh / Mohammad R. Hatshan / Nourah B. Altheeb / Syed Farooq Adil

    Journal of Saudi Chemical Society, Vol 27, Iss 3, Pp 101619- (2023)

    2023  

    Abstract: New ligand (E)-4-((dimethylamino)methyl)-2-((4,5-dimethylthiazol-2-yl)diazenyl)phenol (HDmazo) was prepared by the coupling reaction between 4,5-dimethylthiazol-2-amine and 4-((dimethylamino)methyl)phenol. Moreover, the [MCl2(HDmazo)] and [M(HDmazo)2] [ ... ...

    Abstract New ligand (E)-4-((dimethylamino)methyl)-2-((4,5-dimethylthiazol-2-yl)diazenyl)phenol (HDmazo) was prepared by the coupling reaction between 4,5-dimethylthiazol-2-amine and 4-((dimethylamino)methyl)phenol. Moreover, the [MCl2(HDmazo)] and [M(HDmazo)2] [MII = Pd and Pt] were prepared using the direct reaction of equivalent molar of HDmazo and Na2PdCl4 or K2PtCl4. The HDmazo and its complexes were investigated by different spectroscopic techniques. In complexes (1–2) HDmazo ligand behaves as bidentate style through the nitrogen of azo group and nitrogen of thiazole ring towards Pd(II) and Pt(II). Or in a bidentate fashion via the oxygen atom of the hydroxylate group and nitrogen atom of azo group as mono-anion in complexes (3–4). Further, the study of biological activity against four pathogenic bacteria showed that compound (3) exhibited good activity compared to other compounds. Additional the anti-tumor action against A2870 cell lines was screened, and the complexes (1) and (2) displayed good activity with 7.45 ± 0.98 µM and 13.23 ± 1.43 µM, respectively. The binding mechanism of the prepared compounds with EGFR tyrosine kinase, was investigated using molecular docking experiments.
    Keywords Azo dye ; Thiazole ; Biological activity ; Molecular docking ; Palladium ; Platinum ; Chemistry ; QD1-999
    Subject code 540
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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