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Article ; Online: Augmentation of Enantioselectivity by Spatial Tuning of Aminocatalyst: Synthesis of 2-Alkyl/aryl-3-nitro-2

Mohanta, Rahul / Bez, Ghanashyam

2020 Volume 85, Issue 7, Page(s) 4627–4636

Abstract: The asymmetric oxa-Michael addition of salicylaldehyde to conjugated nitroalkenes often suffers from poor reactivity and selectivity and a long reaction time. Because of the formation of an iminium ion with aminocatalyst, the nucleophilicity of the ... ...

Abstract	The asymmetric oxa-Michael addition of salicylaldehyde to conjugated nitroalkenes often suffers from poor reactivity and selectivity and a long reaction time. Because of the formation of an iminium ion with aminocatalyst, the nucleophilicity of the phenolic hydroxy group in salicylaldehyde reduces further to make the oxa-Michael reaction reversible. Here, we report a structurally simple and easily accessible l-proline derived aminocatalyst, phenyl l-prolinamide, for asymmetric tandem oxa-Michael-Henry reaction of salicylaldehyde with conjugated nitroalkene to give 2-alkyl/aryl-3-nitro-2
Language	English
Publishing date	2020-03-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	123490-0
ISSN	1520-6904 ; 0022-3263
ISSN (online)	1520-6904
ISSN	0022-3263
DOI	10.1021/acs.joc.9b03366
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Book ; Online: The sequence of higher order Mersenne numbers and associated binomial transforms

Prasad, Kalika / Kumari, Munesh / Mohanta, Rabiranjan / Mahato, Hrishikesh

2023

Abstract: In this article, we introduce and study a new integer sequence referred to as the higher order Mersenne sequence. The proposed sequence is analogous to the higher order Fibonacci numbers and closely associated with the Mersenne numbers. Here, we discuss ... ...

Abstract	In this article, we introduce and study a new integer sequence referred to as the higher order Mersenne sequence. The proposed sequence is analogous to the higher order Fibonacci numbers and closely associated with the Mersenne numbers. Here, we discuss various algebraic properties such as Binet's formula, Catalan's identity, d'Ocagne's identity, generating functions, finite and binomial sums, etc. of this new sequence, and some inter-relations with Mersenne and Jacobsthal numbers. Moreover, we study the sequence generated from the binomial transforms of the higher order Mersenne numbers and present the recurrence relation and algebraic properties of them. Lastly, we give matrix generators and tridiagonal matrix representation for higher order Mersenne numbers. Comment: 16 pages
Keywords	Mathematics - Number Theory ; Computer Science - Discrete Mathematics ; Mathematics - Combinatorics ; 11B37 ; 11B39 ; 11B83
Publishing date	2023-07-16
Publishing country	us
Document type	Book ; Online
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Article ; Online: A kaempferol derivative isolated from Lysimachia ramosa (Wall ex. Duby) induced alteration of acetyl cholinesterase and nitric oxide synthase in Raillietina echinobothrida.

Dey, Paulomi / Roy, Bishnupada / Mohanta, Rahul

Veterinary parasitology

2021 Volume 296, Page(s) 109461

Abstract: Lysimachia ramosa has been used as a traditional medicine among the tribal population of Meghalaya, northeast India, for the control of helminthosis. The anthelmintic efficacy of L. ramosa has been documented earlier. In the present study, the active ... ...

Abstract	Lysimachia ramosa has been used as a traditional medicine among the tribal population of Meghalaya, northeast India, for the control of helminthosis. The anthelmintic efficacy of L. ramosa has been documented earlier. In the present study, the active compound from L. ramosa has been isolated and identified using mass and NMR spectra. It's in vitro anthelmintic activity was evaluated against Raillietina echinobothrida, one of the most pathogenic cestode of domestic fowl. The isolated active compound was characterized to be a kaempferol derivative which showed potent anthelmintic activity against R. echinobothrida by changing surface ultrastructure and also inhibiting the activity of two neurotransmitter enzymes: acetyl cholinesterase (AChE) and nitric oxide synthase (NOS), both of which are known to perform dynamic roles in the intracellular communication mediated through neuromuscular system. Motility reduction, deformation in the surface architecture, extensive ultrastructural alterations and reduced histochemical stain intensity in both AChE and NOS was observed in the treated parasites. Biochemical result also revealed alteration in the enzyme activities in the treated parasites. Further, depletion in the nitric oxide (NO) production in the bioactive component exposed tissues of R. echinobothrida was also detected. The results provided evidence that the bioactive compound could be further explored to control helminthosis at a large scale.
MeSH term(s)	Acetylcholinesterase/metabolism ; Animals ; Anthelmintics/pharmacology ; Cestoda/drug effects ; Cestoda/enzymology ; Enzyme Activation/drug effects ; Kaempferols/pharmacology ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism ; Primulaceae/chemistry
Chemical Substances	Anthelmintics ; Kaempferols ; Nitric Oxide (31C4KY9ESH) ; Nitric Oxide Synthase (EC 1.14.13.39) ; Acetylcholinesterase (EC 3.1.1.7)
Language	English
Publishing date	2021-06-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	196831-2
ISSN	1873-2550 ; 0304-4017
ISSN (online)	1873-2550
ISSN	0304-4017
DOI	10.1016/j.vetpar.2021.109461
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Book ; Online: Updated sensitivity of DUNE in 3+1 scenario with far and near detectors

Ghosh, Monojit / Mohanta, Rukmani

2021

Abstract: In this paper we present the updated physics sensitivity of DUNE in presence of a light sterile neutrino with both far and near detectors. In the previous studies, the sensitivities were obtained using the configuration of DUNE as described in the ... ...

Abstract	In this paper we present the updated physics sensitivity of DUNE in presence of a light sterile neutrino with both far and near detectors. In the previous studies, the sensitivities were obtained using the configuration of DUNE as described in the conceptual design report (CDR). In this article, we consider the configuration of DUNE as given in the technical design report (TDR) and study the capability of this experiment to constrain the sterile mixing parameters as well as its capability to measure the standard oscillation parameters in 3+1 scenario. Our results show that in 3+1 scenario, the sensitivity of DUNE to measure the mass hierarchy, octant and CP violation deteriorates if we only consider the far detector. However, a combined analysis of far and near detector improves the sensitivity. Comment: 5 pages, 2 figures, Invited article for "The European Physical Journal Special Topics" of "Symmetry, Dynamics and Strings: A Centennial Issue in Honor of Yoichiro Nambu"
Keywords	High Energy Physics - Phenomenology ; High Energy Physics - Experiment
Subject code	910
Publishing date	2021-10-12
Publishing country	us
Document type	Book ; Online
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Book ; Online: Distinguishing Non-Standard Interaction and Lorentz Invariance Violation at Protvino to Super-ORCA experiment

Majhi, Rudra / Singha, Dinesh Kumar / Ghosh, Monojit / Mohanta, Rukmani

2022

Abstract: As the two phenomena, non-standard interaction (NSI) in neutrino propagation and Lorentz invariance violation (LIV) modify the Hamiltonian of neutrino oscillation in a similar fashion, it is very difficult to distinguish these two effects. The only ... ...

Abstract	As the two phenomena, non-standard interaction (NSI) in neutrino propagation and Lorentz invariance violation (LIV) modify the Hamiltonian of neutrino oscillation in a similar fashion, it is very difficult to distinguish these two effects. The only difference between them lies in the fact that NSI depends on the matter density, whereas LIV is independent of the earth matter effect. Therefore for a fixed baseline experiment, where matter density is constant, the theories describing NSI and LIV are exactly equivalent. However, as the present and future bounds of the NSI and LIV parameters are not equivalent, one can distinguish these two scenarios in the long-baseline neutrino experiments depending on their statistics with respect to the present and future bounds of these parameters. In this paper, we attempt to differentiate between LIV and NSI in the context of DUNE and P2SO, as these two future experiments are believed to be sensitive to the strongest matter effect and will have very large statistics. Taking LIV in the data and NSI in theory, our results show that, indeed it is possible to have good discrimination between LIV and NSI. The best separation between LIV and NSI at $3 \sigma$ C.L. is achieved for the parameter $a_{\mu\mu}$ with P2SO. In this case, the value of LIV parameter for which separation is possible, lies within its future bound, if one considers the value of NSI parameter to be constrained by the present experiments. Between DUNE and P2SO, the latter has better sensitivity for such discrimination. Comment: 11 pages, 5 figures, 5 tables, version accepted for publication in Phys. Rev. D
Keywords	High Energy Physics - Phenomenology
Subject code	612
Publishing date	2022-12-14
Publishing country	us
Document type	Book ; Online
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Book ; Online: Parallel scalable simulations of biological neural networks using TensorFlow

Mohanta, Rishika / Assisi, Collins

A beginner's guide

2019

Abstract: Biological neural networks are often modeled as systems of coupled, nonlinear, ordinary or partial differential equations. The number of differential equations used to model a network increases with the size of the network and the level of detail used to ...

Abstract	Biological neural networks are often modeled as systems of coupled, nonlinear, ordinary or partial differential equations. The number of differential equations used to model a network increases with the size of the network and the level of detail used to model individual neurons and synapses. As one scales up the size of the simulation, it becomes essential to utilize powerful computing platforms. While many tools exist that solve these equations numerically, they are often platform-specific. Further, there is a high barrier of entry to developing flexible platform-independent general-purpose code that supports hardware acceleration on modern computing architectures such as GPUs/TPUs and Distributed Platforms. TensorFlow is a Python-based open-source package designed for machine learning algorithms. However, it is also a scalable environment for a variety of computations, including solving differential equations using iterative algorithms such as Runge-Kutta methods. In this article and the accompanying tutorials, we present a simple exposition of numerical methods to solve ordinary differential equations using Python and TensorFlow. The tutorials consist of a series of Python notebooks that, over the course of five sessions, will lead novice programmers from writing programs to integrate simple one-dimensional ordinary differential equations using Python to solving a large system (1000's of differential equations) of coupled conductance-based neurons using a highly parallelized and scalable framework. Embedded with the tutorial is a physiologically realistic implementation of a network in the insect olfactory system. This system, consisting of multiple neuron and synapse types, can serve as a template to simulate other networks. Comment: Download the associated tutorials from https://github.com/neurorishika/PSST or http://doi.org/10.17605/OSF.IO/YBZKQ. You can also find them online as a JupyterBook here: https://neurorishika.github.io/PSST. Revision Notes: The manuscript and the online tutorials have been ...
Keywords	Quantitative Biology - Neurons and Cognition ; Quantitative Biology - Quantitative Methods
Subject code	518
Publishing date	2019-06-10
Publishing country	us
Document type	Book ; Online
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Book ; Online: Exploring the role of new physics in $b \to u \tau \bar \nu$ decays

Bhatta, Aishwarya / Ray, Atasi / Mohanta, Rukmani

2020

Abstract: The recent measurements on $R_D$, $R_{D^*}$ and $R_{J/\psi}$ by three pioneering experiments, BaBar, Belle and LHCb, indicate that the notion of lepton flavour universality is violated in the weak charged-current processes, mediated through $b \to c \ell ...

Abstract	The recent measurements on $R_D$, $R_{D^}$ and $R_{J/\psi}$ by three pioneering experiments, BaBar, Belle and LHCb, indicate that the notion of lepton flavour universality is violated in the weak charged-current processes, mediated through $b \to c \ell \bar \nu_\ell$ transitions. These intriguing results, which delineate a tension with their standard model predictions at the level of $(2-3)\sigma$ have triggered many new physics propositions in recent times, and are generally attributed to the possible implication of new physics in $ b \to c \tau \bar \nu$ transition. This, in turn, opens up another avenue, i.e., $ b \to u \tau \bar \nu$ processes, to look for new physics. Since these processes are doubly Cabibbo suppressed, the impact of new physics could be significant enough, leading to sizeable effects in some of the observables. In this work, we investigate in detail the role of new physics in $B \to (\pi,\rho,\omega)\tau \bar \nu$ and $B_s \to (K,K^) \tau \bar \nu$ processes considering a model independent approach. In particular, we focus on the standard observables like branching fraction, lepton flavour non-universality (LNU) parameter, forward-backward asymmetry and polarization asymmetries. We find significant deviations in some of these observables, which can be explored by the currently running experiments LHCb and Belle-II. We also briefly comment on the impact of scalar leptoquark $R_2(3,2,7/6)$ and vector leptoquark $U_1(3,1,2/3)$ on these decay modes. Comment: 23 pages, 7 figures, published version
Keywords	High Energy Physics - Phenomenology
Subject code	612
Publishing date	2020-09-07
Publishing country	us
Document type	Book ; Online
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Article ; Online: Correction: Contact tracing of COVID-19 in Karnataka, India: Superspreading and determinants of infectiousness and symptomatic infection.

Gupta, Mohak / Parameswaran, Giridara G / Sra, Manraj S / Mohanta, Rishika / Patel, Devarsh / Gupta, Amulya / Bansal, Bhavik / Jain, Vardhmaan / Mazumder, Archisman / Arora, Mehak / Aggarwal, Nishant / Bhatnagar, Tarun / Akhtar, Jawaid / Pandey, Pankaj / Ravi, Vasanthapuram / Babu, Giridhara R

PloS one

2024 Volume 19, Issue 1, Page(s) e0298090

Abstract: This corrects the article DOI: 10.1371/journal.pone.0270789.]. ...

Abstract	[This corrects the article DOI: 10.1371/journal.pone.0270789.].
Language	English
Publishing date	2024-01-26
Publishing country	United States
Document type	Published Erratum
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0298090
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Book ; Online: Optimal configuration of Protvino to ORCA experiment for hierarchy and non-standard interactions

Singha, Dinesh Kumar / Ghosh, Monojit / Majhi, Rudra / Mohanta, Rukmani

2021

Abstract: In this paper, we study the hierarchy sensitivity of Protvino to ORCA (P2O) experiment in three flavour scenario as well as its sensitivity to non-standard interactions (NSI) in neutrino propagation. Because of the largest possible baseline length of ... ...

Abstract	In this paper, we study the hierarchy sensitivity of Protvino to ORCA (P2O) experiment in three flavour scenario as well as its sensitivity to non-standard interactions (NSI) in neutrino propagation. Because of the largest possible baseline length of 2595 km, P2O is expected to have strong sensitivity towards neutrino mass hierarchy and NSI parameters. In our study, we show that even though the number of appearance channel events for the minimal configuration of P2O are higher compared to DUNE, still the hierarchy sensitivity of P2O is less than DUNE because of large background events. Our results show that for a background reduction factor of 0.46 and appearance channel background systematic normalization error of $4\%$, the hierarchy sensitivity of P2O becomes equivalent of DUNE for $\delta_{\rm CP} = 195^\circ$. We call this configuration of P2O as optimized P2O. Regarding the study of NSI, we find that, for $\epsilon_{e\mu}$ ($\epsilon_{e\tau}$) sensitivity of DUNE is similar (better) as compared to optimized P2O when both $\epsilon_{e\mu}$ and $\epsilon_{e\tau}$ are included in the analysis. Our results show that in presence of NSI, the change of hierarchy sensitivity with respect to standard three flavor scenario, is higher in P2O as compared to DUNE. Further, hierarchy sensitivity in presence of NSI is lower (higher) than sensitivity in the standard three flavour scenario for $\delta_{\rm CP} = 270^\circ (90^\circ)$. It is important to note that hierarchy sensitivity of optimized P2O does not get significantly better than DUNE for the current favourable values of $\delta_{\rm CP}$ which is $180^\circ < \delta_{\rm CP} < 360^\circ$ as obtained by the global analysis in both standard three flavour and in presence of NSI. Comment: 22 pages, 7 figures, 5 tables, version accepted for publication in JHEP
Keywords	High Energy Physics - Phenomenology
Subject code	910
Publishing date	2021-12-09
Publishing country	us
Document type	Book ; Online
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Article ; Online: A field-based quantitative analysis of sublethal effects of air pollution on pollinators.

Thimmegowda, Geetha G / Mullen, Susan / Sottilare, Katie / Sharma, Ankit / Mohanta, Rishika / Brockmann, Axel / Dhandapany, Perundurai S / Olsson, Shannon B

Proceedings of the National Academy of Sciences of the United States of America

2020 Volume 117, Issue 34, Page(s) 20653–20661

Abstract: While the impact of air pollution on human health is well studied, mechanistic impacts of air pollution on wild systems, including those providing essential ecosystem services, are largely unknown, but directly impact our health and well-being. India is ... ...

Abstract	While the impact of air pollution on human health is well studied, mechanistic impacts of air pollution on wild systems, including those providing essential ecosystem services, are largely unknown, but directly impact our health and well-being. India is the world's largest fruit producer, second most populous country, and contains 9 of the world's 10 most polluted cities. Here, we sampled Giant Asian honey bees,
MeSH term(s)	Air Pollution/adverse effects ; Animals ; Bees/drug effects ; Bees/physiology ; Cities ; Drosophila melanogaster/drug effects ; Drosophila melanogaster/physiology ; Ecosystem ; Evaluation Studies as Topic ; Humans ; India ; Insecta/physiology ; Particulate Matter/adverse effects ; Pollination/physiology
Chemical Substances	Particulate Matter
Language	English
Publishing date	2020-08-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2009074117
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