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  1. Article ; Online: Rare association of aneurysm of anterior mitral leaflet with bicuspid aortic valve.

    Mohanty, Vivek / Sharma, Shubham Kumar / Deora, Surender

    Annals of African medicine

    2024  Volume 22, Issue 4, Page(s) 554–556

    Abstract: Mitral valve aneurysm is defined as outpouching of the mitral valve which expands in systole and collapse in diastole. It was first reported in 1729 by Morand. Most of the cases have been described in the African population. It is rare in the Indian ... ...

    Abstract Mitral valve aneurysm is defined as outpouching of the mitral valve which expands in systole and collapse in diastole. It was first reported in 1729 by Morand. Most of the cases have been described in the African population. It is rare in the Indian population. Its chief presentations are congestive heart failure, palpitations, arrhythmia, or in rare cases an embolic phenomenon. It can be diagnosed either by echocardiography or cardiac imaging (magnetic resonance imaging/computed tomography). It can either occur as an isolated defect or with other associated valvular abnormalities. Here, we present a case of a 40-year-old male who was referred for the evaluation of palpitation who on the investigation was found to have a bicuspid aortic valve with severe Aortic Regurgitation (AR) along with aneurysm in the anterior mitral leaflet causing severe mitral regurgitation. This case highlights the importance of keeping a submitral aneurysm as a differential diagnosis for mitral regurgitation and searching for other associated valvular defects which may affect the management and treatment outcomes.
    MeSH term(s) Male ; Humans ; Adult ; Mitral Valve/diagnostic imaging ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/etiology ; Bicuspid Aortic Valve Disease/complications ; Aneurysm/complications ; Echocardiography/adverse effects ; Echocardiography/methods
    Language English
    Publishing date 2024-02-12
    Publishing country India
    Document type Case Reports
    ZDB-ID 2165792-0
    ISSN 0975-5764 ; 0975-5764
    ISSN (online) 0975-5764
    ISSN 0975-5764
    DOI 10.4103/aam.aam_142_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Anomalous Double Right Coronary Artery Presenting as Inferior Wall ST-elevation Myocardial Infarction: A Rare Coronary Anomaly.

    Mohanty, Vivek / Sharma, Shubham / Deora, Surender

    Heart views : the official journal of the Gulf Heart Association

    2023  Volume 24, Issue 2, Page(s) 114–118

    Abstract: Congenital anomalous origin of coronary arteries is rare and occurs in 0.2%-2% of patients undergoing coronary angiography (CAG). Most of the cases are benign but may present with life-threatening symptoms such as myocardial ischemia or sudden cardiac ... ...

    Abstract Congenital anomalous origin of coronary arteries is rare and occurs in 0.2%-2% of patients undergoing coronary angiography (CAG). Most of the cases are benign but may present with life-threatening symptoms such as myocardial ischemia or sudden cardiac death. The prognosis depends on the site of origin of the anomalous artery, intramyocardial course, and relation to other great vessel and cardiac structures. Increased awareness and easy availability of noninvasive methods like computed tomography CAG have led to more reporting of such cases. Here, we report the case a 52-year-old male with a double right coronary artery having anomalous origin from a noncoronary aortic cusp detected during CAG which has not been reported in the literature before.
    Language English
    Publishing date 2023-03-24
    Publishing country India
    Document type Case Reports
    ZDB-ID 2575257-1
    ISSN 0976-5123 ; 1995-705X
    ISSN (online) 0976-5123
    ISSN 1995-705X
    DOI 10.4103/heartviews.heartviews_94_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of vitamin supplementation in patients of congestive heart failure deficient in vitamin D: A study at a tertiary care center of North India.

    Mohanty, Vivek / Pathania, Monika / Bhasi, Ankith

    Annals of African medicine

    2022  Volume 21, Issue 2, Page(s) 107–112

    Abstract: Introduction: Heart Failure is a leading cause of mortality worldwide including India. Most cross sectional studies have demonstrated heart failure is associated with deficiency of essential micronutrients including Vitamin D which may play a important ... ...

    Abstract Introduction: Heart Failure is a leading cause of mortality worldwide including India. Most cross sectional studies have demonstrated heart failure is associated with deficiency of essential micronutrients including Vitamin D which may play a important role in pathogenesis of ventricular remodelling in heart failure.
    Aim: Our study performed aimed to determine the effect of supplementation in patients of Heart Failure presenting with Vitamin D deficiency to our institute on severity of Heart Failure.
    Design and method: 97 patients of Heart failure coming to our institute were given conventional therapies for Heart Failure along with Vitamin supplementation based on serum Vitamin D levels and followed up for 3 months.
    Results: Patient of Heart failure having Vitamin D deficiency had significant reduction in cardiac biomarkers (NT-pro BNP levels), improvement in Left ventricular ejection fraction (LVEF) and more favourable reverse remodelling determined by Left ventricular end diastolic and systolic diameter (LVEDD & LVESD) though quality of life determined by WHODAS 2.0 score did not changed following 12 weeks supplementation of High Dose Vitamin D.
    Conclusion: Recognising and treatment of Vitamin D deficiency may determine long term prognosis in patients of Heart Failure.
    MeSH term(s) Cross-Sectional Studies ; Dietary Supplements ; Heart Failure/complications ; Heart Failure/drug therapy ; Humans ; Quality of Life ; Stroke Volume ; Tertiary Care Centers ; Ventricular Function, Left ; Vitamin D/therapeutic use ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/drug therapy ; Vitamins/therapeutic use
    Chemical Substances Vitamins ; Vitamin D (1406-16-2)
    Language English
    Publishing date 2022-07-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 2165792-0
    ISSN 0975-5764 ; 0975-5764
    ISSN (online) 0975-5764
    ISSN 0975-5764
    DOI 10.4103/aam.aam_70_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Idiopathic Isolated Right Ventricular Cardiomyopathy: A Rare Case Report.

    Mohanty, Vivek / Sharma, Shubham Kumar / Goswami, Sourabh / Gudhage, Rahul / Deora, Surender

    Avicenna journal of medicine

    2023  Volume 13, Issue 1, Page(s) 56–59

    Abstract: Idiopathic isolated right ventricular cardiomyopathy is an extremely rare cause of right ventricular failure. Here, we report a case of 65-year-old male presented with chief complaints of dyspnea, fatigue, and bilateral pedal edema for the last 6 months. ...

    Abstract Idiopathic isolated right ventricular cardiomyopathy is an extremely rare cause of right ventricular failure. Here, we report a case of 65-year-old male presented with chief complaints of dyspnea, fatigue, and bilateral pedal edema for the last 6 months. On clinical evaluation, grade II/III pansystolic murmur was present in left parasternal area. Investigations and imaging revealed dilated right atrium and ventricle with normal pulmonary artery pressure without any etiology. Magnetic resonance imaging ruled out other common causes of right ventricular cardiomyopathy; thus, the patient was diagnosed as a case of idiopathic isolated right ventricular cardiomyopathy that is a diagnosis of exclusion.
    Language English
    Publishing date 2023-03-24
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2664414-9
    ISSN 2249-4464 ; 2231-0770
    ISSN (online) 2249-4464
    ISSN 2231-0770
    DOI 10.1055/s-0043-1764376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Association of Novel Hematological Indices with Severity of Coronary Artery Disease using SYNTAX Score in Patients with Acute Coronary Syndrome.

    Mohanty, Vivek / Sharma, Shubham / Goswami, Sourabh / Kaushik, Atul / Choudhary, Rahul / Yadav, Dharamveer / Deora, Surender / Singh, Kuldeep

    Cardiovascular & hematological disorders drug targets

    2023  Volume 23, Issue 3, Page(s) 202–211

    Abstract: Introduction: Recent evidence suggests that systemic inflammation not only plays an important role in the pathogenesis of Acute Coronary Syndrome but also correlates with disease severity. Monocyte-to-high-density lipoprotein cholesterol ratio (MHR), ... ...

    Abstract Introduction: Recent evidence suggests that systemic inflammation not only plays an important role in the pathogenesis of Acute Coronary Syndrome but also correlates with disease severity. Monocyte-to-high-density lipoprotein cholesterol ratio (MHR), Neutrophil-Lymphocyte Ratio (NLR), and Monocyte-Lymphocyte Ratio (MLR) are novel systemic inflammation markers used for predicting the burden of coronary artery disease (CAD) based on SYNTAX Score. This single-center, cross-sectional, observational study compared the association of these novel hematological indices with CAD severity using the SYNTAX Score in ACS patients and aimed to determine the best predictor of the severity of CAD.
    Methods: A total of 403 consecutive patients with ACS who underwent coronary angiography were enrolled. On the basis of the SYNTAX Score, patients were divided into three groups: Low: <22, Moderate 22 - 32 and High ≥ 32. MHR, MLR, and NLR were calculated and correlated with SYNTAX Score.
    Results: All three indices: MHR (r=0.511; p <0.001), MLR (r=0.373; p <0.001), and NLR (r=0.292; p =0.001) showed significant correlation with SYNTAX Score. The MHR ROC was significantly higher than that of MLR (difference between area: 0.158; 95% CI: 0.079-0.259) and NLR (difference between area: 0.279; 95% CI: 0.172-0.419) for the SYNTAX Score. Analysis showed a strong correlation between these indices with SYNTAX Score >22 compared to low scores <22 and that these also related to the LAD as an infarct artery. Multiple regression analysis showed that diabetes mellitus, eGFR, Infarct-related artery left anterior descending (IRALAD), MHR, MLR, and NLR were predictors of the severity of CAD in ACS patients based on SYNTAX Score.
    Conclusion: In ACS patients MHR, MLR, and NLR showed significant correlation with SYNTAX score >22 which may be indicative of severity of disease. MHR is a better predictor of the severity of CAD than MLR and NLR in ACS patients.
    MeSH term(s) Humans ; Coronary Artery Disease/diagnosis ; Acute Coronary Syndrome/diagnosis ; Cross-Sectional Studies ; Inflammation ; Infarction ; Severity of Illness Index
    Language English
    Publishing date 2023-11-12
    Publishing country United Arab Emirates
    Document type Observational Study ; Journal Article
    ZDB-ID 2244164-5
    ISSN 2212-4063 ; 1871-529X
    ISSN (online) 2212-4063
    ISSN 1871-529X
    DOI 10.2174/011871529X269740231102045028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Two case reports of deadly Himalayan bites with tertiary level care: A snake and a possible scorpion.

    Mohanty, Vivek / Dhar, Minakshi / Panda, Prasan Kumar / Walia, Rohit

    International journal of critical illness and injury science

    2019  Volume 9, Issue 2, Page(s) 96–100

    Abstract: In the Himalayan region, there is a prevalence of unknown bites (not much data except media) including snakes with high range of mortality among victims because hilly terrain leads to delay in transportation and delayed initiation of proper treatment due ...

    Abstract In the Himalayan region, there is a prevalence of unknown bites (not much data except media) including snakes with high range of mortality among victims because hilly terrain leads to delay in transportation and delayed initiation of proper treatment due to lack of developed tertiary care centers. These bites can present from local hypersensitivity reactions to neurological, cardiological, respiratory, hematological, musculoskeletal, and renal manifestations. We highlight two cases that presented with delayed and varied manifestations, recovered but delayed with dedicated supportive care. A 25-year-old female presented 3 days after bite from an unknown snake, possibly krait, developed cardiotoxicity, neuroxotoxicity, rhabdomyolysis, and hemolytic features and was managed with antivenom and anticholinesterase therapy along with medroxyprogesterone to facilitate recovery from bite-associated neurotoxicity. A 75-year-old male subjected to an unknown bite possibly a scorpion developed shock which was most likely cardiogenic in nature secondary to toxin and was managed initially using inotropic support. Prazosin was started, and he recovered completely though at a later time. Hence, apart from krait bite presenting as multisystem involvement, anticholinesterase and medroxyprogesterone acetate are vital for survival. Similarly, prazosin has a vital role in the recovery of scorpion bite-induced cardiotoxicity. Many such unknown venomous bites go unreported. Further case studies and case reports are necessary to help redefine the epidemiology of such bites in the Himalayan region that poses a diagnostic and therapeutic challenge.
    Language English
    Publishing date 2019-03-25
    Publishing country India
    Document type Case Reports
    ZDB-ID 2638865-0
    ISSN 2231-5004 ; 2229-5151
    ISSN (online) 2231-5004
    ISSN 2229-5151
    DOI 10.4103/IJCIIS.IJCIIS_6_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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