Article ; Online: Seroprevalence of dengue and chikungunya viruses among urban refugees in Klang Valley, Malaysia.
Transactions of the Royal Society of Tropical Medicine and Hygiene
2024 Volume 118, Issue 5, Page(s) 328–335
Abstract: Background: Mosquito-borne diseases pose a significant global public health threat, with Malaysia's Klang Valley experiencing numerous outbreaks in densely populated urban areas.: Methods: This study aimed to estimate the seroprevalence of anti- ... ...
| Abstract | Background: Mosquito-borne diseases pose a significant global public health threat, with Malaysia's Klang Valley experiencing numerous outbreaks in densely populated urban areas. Methods: This study aimed to estimate the seroprevalence of anti-dengue and anti-chikungunya antibodies among urban refugees in the Klang Valley, Malaysia, and identify associated risk factors. Results: High seroprevalence of anti-dengue immunoglobulin G (IgG) and IgM (60.0% [confidence interval {CI} 55.39 to 64.48] and 9.2% [CI 6.77 to 12.25], respectively) were observed among refugees >18 years of age (χ22=11.720, p=0.003), Kachin ethnicity (χ28=72.253, p<0.001), without formal education (χ21=3.856, p=0.050), homes near waste disposal sites (χ21=10.378, p=0.001) and refugees who have experienced flooding (χ21=5.460, p=0.019). Meanwhile, the overall seroprevalence of anti-chikungunya IgG and IgM was 9.7% (CI 7.15 to 12.73) and 10.8% (CI 8.09 to 13.93), respectively, with ages 12-18 years (χ22=6.075, p=0.048), Rohingya ethnicity (χ28=31.631, p<0.001) and homes close to waste disposal sites (χ21=3.912, p=0.048) being significant risk factors. Results showed a link to poor environmental living conditions, with an increase in the vector population with higher availability of breeding sites and thus exposure to dengue and chikungunya virus. Conclusions: Health education among the community is the key to disease prevention, as there are no specific antiviral drugs for treatment and limited vaccine availability. |
|---|---|
| MeSH term(s) | Humans ; Malaysia/epidemiology ; Seroepidemiologic Studies ; Dengue/epidemiology ; Dengue/immunology ; Dengue/blood ; Male ; Chikungunya Fever/epidemiology ; Chikungunya Fever/blood ; Chikungunya Fever/immunology ; Female ; Adult ; Refugees/statistics & numerical data ; Adolescent ; Child ; Chikungunya virus/immunology ; Young Adult ; Antibodies, Viral/blood ; Immunoglobulin M/blood ; Middle Aged ; Immunoglobulin G/blood ; Dengue Virus/immunology ; Risk Factors ; Child, Preschool ; Urban Population |
| Chemical Substances | Antibodies, Viral ; Immunoglobulin M ; Immunoglobulin G |
| Language | English |
| Publishing date | 2024-01-16 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 441375-1 |
| ISSN | 1878-3503 ; 0035-9203 |
| ISSN (online) | 1878-3503 |
| ISSN | 0035-9203 |
| DOI | 10.1093/trstmh/trad097 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Un I Zs.257: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.