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  1. Article ; Online: Saved by the Bell-Automated Paging Alerts to Improve Sepsis Bundle Compliance.

    Bhavani, Sivasubramanium V / Mohr, Nicholas

    Critical care medicine

    2024  Volume 52, Issue 2, Page(s) 340–342

    MeSH term(s) Humans ; Sepsis/therapy ; Guideline Adherence
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000006087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Pelluzide marginale Degeneration versus Keratokonus-Differentialdiagnostik mittels Weitfeld-SD-OCT

    Mohr, N.

    Der Augenspiegel

    2020  Volume 66, Issue Nov, Page(s) 18

    Language German
    Document type Article
    ZDB-ID 211827-0
    ISSN 0004-7937
    Database Current Contents Medicine

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  3. Article ; Online: Costs of routine skin cancer screening in Germany: a claims data analysis.

    Krensel, M / Andrees, V / Mohr, N / Hischke, S

    Clinical and experimental dermatology

    2021  Volume 46, Issue 5, Page(s) 842–850

    Abstract: Background: In 2008, a routine skin cancer screening (rSCS) programme was implemented in Germany. Since then, its medical and economical effects have been evaluated and critically discussed.: Aim: To compare costs for patients diagnosed with skin ... ...

    Abstract Background: In 2008, a routine skin cancer screening (rSCS) programme was implemented in Germany. Since then, its medical and economical effects have been evaluated and critically discussed.
    Aim: To compare costs for patients diagnosed with skin cancer with preceding rSCS vs. those diagnosed without rSCS.
    Methods: We conducted a retrospective observational study using claims data from a large German health insurance company for the period 2013-2016. We applied entropy balancing, difference-in-differences estimation and generalized linear models to compare costs for patients with cancer with and without rSCS. We conducted sensitivity analyses to test for the robustness of results.
    Results: In total, 12 790 patients with skin cancer were included in the analyses, of whom 6041 were diagnosed by rSCS. Treatment costs were €467 higher for patients in the control group (without rSCS). However, the screening costs were higher. For all people covered by the health insurance company, there were additional costs of €1339-1431 per patient with skin cancer diagnosed by rSCS. Thus, total costs, including costs for treatment and screening, were €872-964 higher for patients diagnosed by rSCS.
    Conclusions: Based on our analysis, rSCS has the potential to reduce treatment costs; however, the screening costs exceed these savings.
    MeSH term(s) Aged ; Case-Control Studies ; Data Analysis ; Early Detection of Cancer/economics ; Early Detection of Cancer/methods ; Female ; Germany/epidemiology ; Health Care Costs/statistics & numerical data ; Health Care Costs/trends ; Humans ; Insurance, Health/economics ; Insurance, Health/statistics & numerical data ; Linear Models ; Male ; Mass Screening/economics ; Mass Screening/standards ; Retrospective Studies ; Sensitivity and Specificity ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology
    Language English
    Publishing date 2021-03-23
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1111/ced.14550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Determinants of costs and benefits in atopic dermatitis routine care in Germany.

    Mohr, N / Augustin, M / Zeervi, L / Bieber, T / Werfel, T / Wollenberg, A / Langenbruch, A

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2022  Volume 36, Issue 9, Page(s) 1450–1455

    Abstract: Background and objectives: The economic burden of atopic dermatitis (AD) is of particular interest. The present study aims to analyse the association of disease-related characteristics, annual costs and treatment benefits in AD.: Methods: Between ... ...

    Abstract Background and objectives: The economic burden of atopic dermatitis (AD) is of particular interest. The present study aims to analyse the association of disease-related characteristics, annual costs and treatment benefits in AD.
    Methods: Between August 2017 and June 2019, a cross-sectional observational study in patients with AD was conducted in Germany. Cost-of-illness data were assessed from the societal perspective. Disease characteristics included severity, time since diagnosis and therapy, as well as atopic comorbidity and the implementation of prevention measures. Subgroup analyses of the total costs were conducted for these characteristics. A linear regression model was applied to analyse the impact of disease characteristics on the costs. Furthermore, associations of biologic treatment with outcome parameters were analysed.
    Results: A total of 1291 patients from 111 centres were included in the analyses. The total costs amounted on average to € 3660 ± € 6428 per patient and year. Higher costs were shown in various patient groups, for example, in patients using biologics (€ 20 983 vs. € 2470). In a regression analysis, gender, education and the number of implemented prevention measures were identified as significant predictors of costs. Patients treated with biologics showed consistently better outcome parameters and were more often satisfied with their treatment.
    Conclusions: Gender, education and implemented prevention measures are significant cost determinants in AD. The results confirm that treatment with biologics is the main cost driver in AD. However, incremental patient-relevant benefits of high-priced therapy are reflected by the significantly better clinical outcomes in the group treated with biologics.
    MeSH term(s) Biological Products ; Cost of Illness ; Cost-Benefit Analysis ; Cross-Sectional Studies ; Dermatitis, Atopic/drug therapy ; Germany ; Health Care Costs ; Humans
    Chemical Substances Biological Products
    Language English
    Publishing date 2022-05-18
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.18169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rapid Sequence Intubation, is it Time to Find an Alternative Induction Agent? A Narrative Review.

    Faine, Brett A / Carroll, Elisabeth / Sharma, Archit / Mohr, Nicholas

    Journal of pharmacy practice

    2023  , Page(s) 8971900231197501

    Abstract: Objective: To review the efficacy, safety, and place in therapy of fentanyl as an induction agent for rapid sequence intubation (RSI) in critically ill patients.: Data sources: A comprehensive search of PubMed, EMBASE, and clinical trial registries ( ... ...

    Abstract Objective: To review the efficacy, safety, and place in therapy of fentanyl as an induction agent for rapid sequence intubation (RSI) in critically ill patients.
    Data sources: A comprehensive search of PubMed, EMBASE, and clinical trial registries (1964-June 2021) was performed utilizing the keywords fentanyl, rapid sequence intubation, intubation, induction, anesthesia, hemodynamics, operating room (OR), and emergency.
    Study selection and data extraction: Only primary literature evaluating fentanyl in combination with a sedative or as the sole induction agent was included in the final analysis. Primary literature included peer-reviewed publications and results posted on ClinicalTrials.gov actively recruiting participants.
    Data synthesis: Fentanyl has been used for decades as an adjunct, and sole induction agent in the OR. Questions surrounding the use of fentanyl as a sole induction agent include optimal dosing and safety in critically ill patients as evaluation in non-OR settings remain limited.
    Relevance to patient care and clinical practice: Commonly used induction agents (eg, etomidate and ketamine) are associated with adverse events that may increase risk of morbidity and mortality. Fentanyl, a high-potency opioid could serve as an alternative induction agent for RSI due to its neutral hemodynamic response and fast onset of action. This paper compiles and describes existing data on the use of fentanyl as an induction agent for RSI.
    Conclusion: Fentanyl in combination with sedatives provides optimal intubating conditions with minimal impact on hemodynamic parameters. Future studies should focus on safety and impact of awareness during paralysis before fentanyl can be considered as a sole induction agent.
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1027474-1
    ISSN 1531-1937 ; 0897-1900
    ISSN (online) 1531-1937
    ISSN 0897-1900
    DOI 10.1177/08971900231197501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Epidemiology of skin diseases in Germany: systematic review of the current state of research - part 1: cutaneous tumor diseases.

    Hansen, Inga / Augustin, Matthias / Schäfer, Ines / Mohr, Nicole

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 3, Page(s) 257–270

    Abstract: Epidemiological data are of great importance for the identification of health care needs, the detection of gaps in care, the development of targeted prevention measures, and for the optimization of resource allocation. The aim of this work was to ... ...

    Abstract Epidemiological data are of great importance for the identification of health care needs, the detection of gaps in care, the development of targeted prevention measures, and for the optimization of resource allocation. The aim of this work was to systematically collect all previously published population-based epidemiological data on skin diseases in Germany. The present part 1 of the publication series deals with tumor diseases of the skin. The results on non-infectious (part 2) and infectious skin diseases (part 3) form the other parts of this publication series. A systematic search of the literature spanning the last 15 years was conducted using the PubMed/MEDLINE database. With the aim of including all dermatologic diseases, a diagnostic list was developed based on the ICD-11 catalogue. This list included 1,347 skin diseases and formed the basis for the search. The literature search yielded 4,650 publications. After two-stage screening, 72 studies on 43 different skin diseases were included in the synthesis. Among them were 30 publications on cutaneous tumor diseases, the majority was related to malignant melanoma. This work is the first systematic literature review that aimed to report all available epidemiological data on skin diseases in Germany. In terms of study characteristics, a high heterogeneity was found for the different skin diseases. Even though the methodology of the included epidemiological studies varied considerably, the usefulness of these epidemiological data is extremely wide-ranging. Thus, this work can serve as a reference for various epidemiological questions.
    MeSH term(s) Germany/epidemiology ; Humans ; Melanoma/diagnosis ; Melanoma/epidemiology ; Melanoma/pathology ; Skin/pathology ; Skin Neoplasms/diagnosis ; Skin Neoplasms/epidemiology ; Skin Neoplasms/pathology
    Language English
    Publishing date 2022-03-04
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14746
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Epidemiologie von Hautkrankheiten in Deutschland: Systematische Literaturanalyse des aktuellen Forschungsstands - Teil 3: infektiöse Hauterkrankungen.

    Hansen, Inga / Augustin, Matthias / Schäfer, Ines / Mohr, Nicole

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 5, Page(s) 589–596

    Language English
    Publishing date 2022-05-17
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14702_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Epidemiologie von Hautkrankheiten in Deutschland: systematische Literaturanalyse des aktuellen Forschungsstands - Teil 2: nichtinfektiöse Hauterkrankungen.

    Hansen, Inga / Augustin, Matthias / Schäfer, Ines / Mohr, Nicole

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 4, Page(s) 445–457

    Language English
    Publishing date 2022-04-19
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14727_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Epidemiologie von Hautkrankheiten in Deutschland: systematische Literaturanalyse des aktuellen Forschungsstands - Teil 1: Tumorerkrankungen der Haut.

    Hansen, Inga / Augustin, Matthias / Schäfer, Ines / Mohr, Nicole

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 3, Page(s) 257–271

    Language English
    Publishing date 2022-02-27
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14746_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Epidemiology of skin diseases in Germany: systematic review of the current state of research - part 3: infectious skin diseases.

    Hansen, Inga / Augustin, Matthias / Schäfer, Ines / Mohr, Nicole

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 5, Page(s) 589–595

    Abstract: The aim of this work was to systematically collect all previously published population-based epidemiological data on skin diseases in Germany. A systematic literature search was performed using PubMed/MEDLINE for the period of the last 15 years. With the ...

    Abstract The aim of this work was to systematically collect all previously published population-based epidemiological data on skin diseases in Germany. A systematic literature search was performed using PubMed/MEDLINE for the period of the last 15 years. With the aim to include all dermatological diseases, a diagnostic list based on the ICD-11 catalogue was compiled. This list included 1,347 skin diseases and formed the basis for the search. The present part 3 of the publication series deals with infectious skin diseases. The results on cutaneous tumor diseases (part 1) and non-infectious skin diseases (part 2) form the other parts of this publication series. The literature search yielded 4,605 hits, of which 72 papers on 43 different skin diseases were included in the synthesis. Among them were twelve hits on infectious dermatoses, of which six papers were related to measles. The highest lifetime prevalence rates were found for varicella and verrucae vulgaris. This work is the first systematic literature review that aimed to report all available epidemiological data on skin diseases in Germany. It was found that representative data on many infectious diseases are not yet available. Among the included studies, a high heterogeneity was found with regard to the methodology. Nevertheless, these epidemiological data have a wide range of uses and can serve as a reference for various epidemiological questions.
    MeSH term(s) Germany/epidemiology ; Humans ; Measles ; Noncommunicable Diseases ; Skin/pathology ; Skin Diseases, Infectious/epidemiology ; Skin Neoplasms/pathology
    Language English
    Publishing date 2022-04-05
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14702
    Database MEDical Literature Analysis and Retrieval System OnLINE

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