LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 2 of total 2

Search options

  1. Article: Exploring the therapeutic potential of

    Abd Rahman, Rassheda / Jayasingh Chellammal, Hanish Singh / Ali Shah, Syed Adnan / Mohd Zohdi, Rozaini / Ramachandran, Dhani / Mohsin, Hannis Fadzillah

    Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

    2024  Volume 32, Issue 4, Page(s) 102016

    Abstract: ... Derris ... ...

    Abstract Derris elliptica
    Language English
    Publishing date 2024-02-28
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 1378024-4
    ISSN 1319-0164
    ISSN 1319-0164
    DOI 10.1016/j.jsps.2024.102016
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4758: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Physical Characterisation and Stability Study of Formulated

    Zamram, Qurratul Ain Zakirah Mohd / Mohsin, Hannis Fadzillah / Mohamad, Mashani / Nor Hazalin, Nurul Aqmar Mohamad / Hamid, Khuriah Abdul

    Current drug delivery

    2022  Volume 19, Issue 4, Page(s) 479–490

    Abstract: Background: Formulation of topical products for skin delivery that fulfill good formulation criteria has always been a challenge for pharmaceutical scientists. Despite the challenges, gelbased drug delivery offers some advantages such that it is non- ... ...

    Abstract Background: Formulation of topical products for skin delivery that fulfill good formulation criteria has always been a challenge for pharmaceutical scientists. Despite the challenges, gelbased drug delivery offers some advantages such that it is non-invasive, painless, involves avoidance of the first-pass metabolism, and has satisfactory patient compliance.
    Objectives: In this study, C. odorata gel and quercetin gel (bioactive flavonoid compound) were successfully formulated and compared with placebo and conventional wound aid gel. The chromatographic profiling was conducted to screen the presence of phytoconstituents. Subsequently, all formulated gels were evaluated for physical characteristics and stability.
    Methods: Reverse Phase High-Performance Liquid Chromatography (RP-HPLC) of C. odorata methanolic leaves extract showed a distinct compound separation at a retention time of 8.4min to 34.8 min at 254nm. All gels were characterised by evaluating their rheological properties, including storage modulus, loss modulus, and plastic viscosity. Besides, texture analysis was performed to measure the firmness, consistency, cohesiveness, and viscosity index of the gels.
    Results: According to the results, C. odorata gel demonstrated better spreadability as compared to the other gels, which required less work and was found to be favourable for application on the skin. Moreover, C. odorata gel showed no changes in organoleptic properties and proven to be stable after 30 days of accelerated stability study at 40°C ± 2°C with Relative Humidity (RH) of 75% ± 5%.
    Conclusion: C. odorata gel was found to be stable, reflecting the combination of materials used in the formulation, which did not degrade throughout the study. This work suggests the potential of this gel as a vehicle to deliver the active ingredients of C. odorata to the skin, which can be further explored as a topical application for antimicrobial wound management or other skin diseases study.
    MeSH term(s) Chromolaena/chemistry ; Gels/chemistry ; Humans ; Plant Leaves/chemistry ; Rheology ; Viscosity
    Chemical Substances Gels
    Language English
    Publishing date 2022-10-05
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2185284-4
    ISSN 1875-5704 ; 1567-2018
    ISSN (online) 1875-5704
    ISSN 1567-2018
    DOI 10.2174/1567201818666210419114809
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6415: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top