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  1. Article ; Online: Hepatic Metastasis via a Ventriculo-Peritoneal Shunt from an Intracranial Meningioma: Case Report and Review of the Literature.

    Moir, J A G / Haugk, B / French, J J

    Case reports in gastroenterology

    2010  Volume 4, Issue 2, Page(s) 267–272

    Abstract: Meningiomas are slow-growing intracranial/intraspinal tumours, with a wide range of histopathological variants. The more aggressive atypical and malignant types can disseminate via the venous system, lymphatics or cerebrospinal fluid, with the lungs and ... ...

    Abstract Meningiomas are slow-growing intracranial/intraspinal tumours, with a wide range of histopathological variants. The more aggressive atypical and malignant types can disseminate via the venous system, lymphatics or cerebrospinal fluid, with the lungs and pleura being the most common site of extracranial metastasis. We look at a 68-year-old woman presenting with abdominal pain, who had previously been treated for an intracranial meningioma with a ventriculo-peritoneal shunt in situ. Investigation revealed a lesion in segment 4 of the liver with the shunt tip being in close proximity. Biopsy was consistent with metastatic meningioma. A liver resection was subsequently performed. We postulate that this is the first reported case of dissemination of an intracranial meningioma via cerebrospinal fluid by means of a ventriculo-peritoneal shunt.
    Language English
    Publishing date 2010-08-02
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631 ; 1662-0631
    ISSN (online) 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000316118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Selective internal radiation therapy for liver malignancies.

    Moir, J A G / Burns, J / Barnes, J / Colgan, F / White, S A / Littler, P / Manas, D M / French, J J

    The British journal of surgery

    2015  Volume 102, Issue 12, Page(s) 1533–1540

    Abstract: Background: Selective internal radiation therapy (SIRT) is a non-ablative technique for the treatment of liver primaries and metastases, with the intention of reducing tumour bulk. This study aimed to determine optimal patient selection, and elucidate ... ...

    Abstract Background: Selective internal radiation therapy (SIRT) is a non-ablative technique for the treatment of liver primaries and metastases, with the intention of reducing tumour bulk. This study aimed to determine optimal patient selection, and elucidate its role as a downsizing modality.
    Methods: Data were collected retrospectively on patients who underwent SIRT between 2011 and 2014. The procedure was performed percutaneously by an expert radiologist. Response was analysed in two categories, based on radiological (CT/MRI according to Response Evaluation Criteria In Solid Tumours (RECIST)) and biological (α-fetoprotein, carcinoembryonic antigen, carbohydrate antigen 19-9, chromogranin A) parameters.
    Results: Forty-four patients were included. Liver metastases from colorectal cancer (22 patients) and hepatocellular carcinoma (HCC) (9) were the most common pathologies. Radiological response data were collected from 31 patients. A reduction in sum of diameters (SOD) was observed in patients with HCC (median -24.1 (95 per cent c.i. -43.4 to -3.8) per cent) and neuroendocrine tumours (-30.0 (-45.6 to -7.7) per cent), whereas a slight increase in SOD was seen in patients with colorectal cancer (4.9 (-10.6 to 55.3) per cent). Biological response was assessed in 17 patients, with a reduction in 12, a mixed response in two and no improvement in three. Six- and 12-month overall survival rates were 71 and 41 per cent respectively. There was no difference in overall survival between the RECIST response groups (median survival 375, 290 and 214 days for patients with a partial response, stable disease and progressive disease respectively; P = 0.130), or according to primary pathology (P = 0.063). Seven patients underwent liver resection with variable responses after SIRT.
    Conclusion: SIRT may be used to downsize tumours and may be used as a bridge to surgery in patients with tumours deemed borderline for resection.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Carcinoma, Hepatocellular ; Female ; Follow-Up Studies ; Humans ; Liver Neoplasms/diagnosis ; Liver Neoplasms/mortality ; Liver Neoplasms/radiotherapy ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neoplasm Staging ; Radiation Dosage ; Retrospective Studies ; Survival Rate ; Time Factors ; Tomography, X-Ray Computed ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2015-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.9924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Posttransplant lymphoproliferative disorder presenting as multiple cystic lesions in a renal transplant recipient.

    Moir, J A G / Simms, R J / Wood, K M / Talbot, D / Kanagasundaram, N S

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2012  Volume 12, Issue 1, Page(s) 245–249

    Abstract: We report a case of a 67-year-old man who experienced allograft dysfunction following a renal transplantation from a donation after cardiac death. The postoperative course was initially complicated by episodes of E. coli urinary sepsis causing pyrexia ... ...

    Abstract We report a case of a 67-year-old man who experienced allograft dysfunction following a renal transplantation from a donation after cardiac death. The postoperative course was initially complicated by episodes of E. coli urinary sepsis causing pyrexia and a raised creatinine level. Ultrasound scanning 5 weeks posttransplant revealed mild hydronephrosis with several parenchymal cystic areas measuring up to 2 cm with appearances suggestive of fungal balls. Aspirated fluid again grew Escherichia coli, and this was treated with the appropriate antimicrobial therapy. The patient continued to have episodes of culture-negative sepsis; therefore, a computed tomography scan was performed 6 months posttransplant, which revealed multiple lesions in the renal cortex as well as liver and spleen. Subsequent biopsy revealed an Epstein-Barr virus-driven lymphoproliferation consistent with a polymorphic posttransplantation lymphoproliferative disorder (PTLD). This rare case of PTLD presenting as multiple renal, hepatic and splenic lesions emphasizes the need for a high index of clinical suspicion for this condition. Abnormal para-renal allograft masses should be biopsied to allow swift and effective management of a disease that can disseminate and become significantly more challenging to manage.
    MeSH term(s) Aged ; Anti-Bacterial Agents/therapeutic use ; Escherichia coli Infections/drug therapy ; Humans ; Kidney Diseases/surgery ; Kidney Transplantation/adverse effects ; Lymphoproliferative Disorders/etiology ; Male
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2012-02-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/j.1600-6143.2011.03761.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Isolated splenic metastasis from renal cell carcinoma: case report and review.

    Moir, J A G / Sen, G / Saif, R / Haugk, B / French, J J

    Case reports in gastroenterology

    2011  Volume 5, Issue 1, Page(s) 166–171

    Abstract: This report presents the case of a 70-year-old woman with a previous history of a left nephrectomy for renal cell carcinoma (RCC), who developed general malaise and fatigue. Abdominal computed tomography demonstrated an enhancing 6 × 7 cm necrotic lesion ...

    Abstract This report presents the case of a 70-year-old woman with a previous history of a left nephrectomy for renal cell carcinoma (RCC), who developed general malaise and fatigue. Abdominal computed tomography demonstrated an enhancing 6 × 7 cm necrotic lesion in the lower pole of the spleen suggestive of a metastasis. Given the highly suspicious nature of the lesion we proceeded to splenectomy. The tumour did not breach the splenic capsule, and there was no local diaphragmatic involvement. The mass was concluded to be a true metastasis of the original RCC rather than local recurrence of the disease. The causes of isolated solid splenic lesions are wide and varied, however a past or present history of malignancy should lead to a high index of suspicion for a splenic metastasis. We report an extremely unusual case of spread from a RCC.
    Language English
    Publishing date 2011-04-12
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631 ; 1662-0631
    ISSN (online) 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000326963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hepatic Metastasis via a Ventriculo-Peritoneal Shunt from an Intracranial Meningioma: Case Report and Review of the Literature

    Moir, J.A.G. / Haugk, B. / French, J.J.

    Case Reports in Gastroenterology

    2010  Volume 4, Issue 2, Page(s) 267–272

    Abstract: Meningiomas are slow-growing intracranial/intraspinal tumours, with a wide range of histopathological variants. The more aggressive atypical and malignant types can disseminate via the venous system, lymphatics or cerebrospinal fluid, with the lungs and ... ...

    Institution Departments of Hepato-Pancreatic-Biliary Surgery and Pathology, Freeman Hospital, Newcastle, UK
    Abstract Meningiomas are slow-growing intracranial/intraspinal tumours, with a wide range of histopathological variants. The more aggressive atypical and malignant types can disseminate via the venous system, lymphatics or cerebrospinal fluid, with the lungs and pleura being the most common site of extracranial metastasis. We look at a 68-year-old woman presenting with abdominal pain, who had previously been treated for an intracranial meningioma with a ventriculo-peritoneal shunt in situ. Investigation revealed a lesion in segment 4 of the liver with the shunt tip being in close proximity. Biopsy was consistent with metastatic meningioma. A liver resection was subsequently performed. We postulate that this is the first reported case of dissemination of an intracranial meningioma via cerebrospinal fluid by means of a ventriculo-peritoneal shunt.
    Keywords Ventriculo-peritoneal shunt ; Hepatic metastasis ; Meningioma
    Language English
    Publishing date 2010-08-02
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    ZDB-ID 2440540-1
    ISSN 1662-0631 ; 1662-0631
    ISSN (online) 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000316118
    Database Karger publisher's database

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  6. Article: Isolated Splenic Metastasis from Renal Cell Carcinoma: Case Report and Review

    Moir, J.A.G. / Sen, G. / Saif, R. / Haugk, B. / French, J.J.

    Case Reports in Gastroenterology

    2011  Volume 5, Issue 1, Page(s) 166–171

    Abstract: This report presents the case of a 70-year-old woman with a previous history of a left nephrectomy for renal cell carcinoma (RCC), who developed general malaise and fatigue. Abdominal computed tomography demonstrated an enhancing 6 × 7 cm necrotic lesion ...

    Institution Departments of Hepatobiliary and Pancreatic Surgery and Pathology, Freeman Hospital, Newcastle upon Tyne, UK
    Abstract This report presents the case of a 70-year-old woman with a previous history of a left nephrectomy for renal cell carcinoma (RCC), who developed general malaise and fatigue. Abdominal computed tomography demonstrated an enhancing 6 × 7 cm necrotic lesion in the lower pole of the spleen suggestive of a metastasis. Given the highly suspicious nature of the lesion we proceeded to splenectomy. The tumour did not breach the splenic capsule, and there was no local diaphragmatic involvement. The mass was concluded to be a true metastasis of the original RCC rather than local recurrence of the disease. The causes of isolated solid splenic lesions are wide and varied, however a past or present history of malignancy should lead to a high index of suspicion for a splenic metastasis. We report an extremely unusual case of spread from a RCC.
    Keywords Spleen ; Metastasis ; Renal cell carcinoma
    Language English
    Publishing date 2011-04-12
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    ZDB-ID 2440540-1
    ISSN 1662-0631 ; 1662-0631
    ISSN (online) 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000326963
    Database Karger publisher's database

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  7. Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

    Nepogodiev D. / Bhangu A. / Glasbey J.C. / Li E. / Omar O.M. / Simoes J.F. / Abbott T.E. / Alser O. / Arnaud A.P. / Bankhead-Kendall B.K. / Breen K.A. / Cunha M.F. / Davidson G.H. / Di Saverio S. / Gallo G. / Griffiths E.A. / Gujjuri R.R. / Hutchinson P.J. / Kaafarani H.M. /
    Lederhuber H. / Loffler M.W. / Mashbari H.N. / Minaya-Bravo A. / Morton D.G. / Moszkowicz D. / Pata F. / Tsoulfas G. / Venn M.L. / Cox D. / Roslani A.C. / Alakaloko F. / de Vries J.-P.P. / Aaraj M.A. / Abbott S.J. / Abdalla M.O. / Abdelaal A.S. / Ademuyiwa A.O. / Aherne T.M. / Ali O.M. / Alkadeeki G.Z. / Almeida A.C. / Alrahawy M.M. / Ambler G.K. / Alameer E. / Andreani S.M. / De Andres-Asenjo B. / Antonanzas L.L. / Aoun S.G. / Ashoush F.M. / Augestad K.M. / Avellana R.B. / Ayeni F.A. / Ayorinde J.O. / Babu B.H. / Baig M.M. / Bajomo O.M. / Baker O.J. / Baker M.P. / Baldwin A.J. / Ban V.S. / Baron R.D. / Barranquero A.G. / Barry C.P. / DI Bartolomeo A. / Bass G.A. / Bath M.F. / Batjer H.H. / Beamish A.J. / Belgaumkar A.P. / Bence M.N. / Benson R.A. / Bernal-Sprekelsen J.C. / Bhama A.R. / Bhavaraju A.V. / Biffl W.L. / Blundell C.M. / Boddy A.P. / Borgstein A.B. / Bosanquet D.C. / Bosch K.D. / Bouhuwaish A.E. / Bozkurt M.A. / Brathwaite C.E. / Brown B.C. / Brown O.D. / Brown A.K. / Buarque I.L. / Bueno-Canones A.D. / Bulugma M.R. / Burke J.R. / Byrne M.H. / Cagigal-Ortega E.P. / Callcut R.A. / DI Candido F. / Canova M.E. / Carlos W.J. / Caruana E.J. / Cato L.D. / Catton A.B. / Ceretti A.P. / Chase T.J. / Chiara F.D. / Chowdhury A.H. / Chung E.A. / Cicerchia P.M. / Clough E.C. / Coleman N.L. / Collins C.G. / Collins M.L. / Colonna E.T. / Comini L.V. / Coughlin P.A. / Cruzado L.F.-G. / Davidson B.R. / Davies R.J. / Davies E.J. / Davis N.F. / Dawson B.E. / Dean B.J. / Delgado M.G.-C. / Diaz J.J. / Dickson K.E. / Diez-Alonso M.M. / Dixon J.R. / Doe M.J. / Drake T.D. / Drake F.T. / Duffy J.P. / Dunne D.F. / Dunne N.J. / Duran-Munoz-Cruzado V.M. / Durst A.Z. / Eardley N.J. / Edwards J.G. / Elfallal A.H. / Elfiky M.M. / Elliott J.A. / Emile S.H. / Emslie K.M. / Endorf F.W. / Engel J.L. / Enjuto D.T. / Etchill E.W. / Evans J.P. / Fahey B.A. / Faria C.S. / Feo C.V. / Ferguson H.J. / Fernandez B.D. / Fernandez A.G. / Fernandez A.J. / Fernandez-Pacheco B.C. / Fitzgerald J.E. / Fonsi G.B. / Font R.F. / Fowler A.L. / Fretwell K.R. / Fructuoso L.S. / Fusai G.K. / Garcia M.H. / Garcia-Urena M.A. / Gill C.K. / Gisbertz S.S. / Del Giudice R. / Giuffrida M.C. / Di Giuseppe M. / Gomez M.F. / Guariglia C.A. / Hainsworth A.J. / Hall B.J. / Hall J.R. / Hammond J.S. / Haqqani M.H. / Harrison E.M. / Hazelton J.P. / van Heinsbergen M. / Hill A.D. / Hing C.B. / Hirji S.A. / Ho M.W. / Holbrook C.M. / Holme T.J. / Hopkins J.C. / Hopkinson D.N. / Hossain F.S. / Hudson V.E. / Hughes J.L. / Hwang E.S. / Ibrahim M.A. / Isolani S.M. / Jenkinson M.D. / Jenny H.E. / Jeyaretna D.S. / Jones R.P. / Jones A.P. / Jonker P.K. / Jonsson M.L. / Joyce D.P. / Kalkwarf K.J. / Kamarajah S.K. / El Kassas M. / Kavanagh D.O. / Keatley J.M. / Khalefa M.A. / Khan J.S. / Kirmani B.H. / Kisiel A.P. / Kouris S.M. / Kowal M.R. / Labib P.L. / Larkin J.O. / Lauscher J.C. / Leclercq W.K. / Ledesma F.S. / Leite-Moreira A.M. / Leung E.Y. / Lewis S.E. / Lima M.J. / Lin D.J. / Liu H.H. / Lowery A.J. / Lozano S.M. / Luney C.R. / Maia M.M. / Mariani N.M. / Marino M.V. / Marra A.A. / Marsh C.L. / Martin R.C. / McCluney S.J. / McIntyre R.C. / Mckay S.C. / McKevitt K.L. / Meagher A.D. / Mehdi M.Q. / Mehigan B.J. / Gonzalez-De Miguel M. / De Miguel-Ardevines M.-C. / Mills S.J. / Mohan H.M. / Moir J.A. / Monson J.R. / Monteiro J.M. / Montella M.T. / Montesinos C.S. / Morgom M.M. / Moura F.S. / Muguerza J.M. / Murphy S.H. / De Nardi P. / Naumann D.N. / Neary P.C. / Neely D.T. / Ng-Kamstra J.S. / Ngu A.W. / Nguyen T.A. / Nita G.E. / Nunes Q.M. / Nygaard R.M. / O'Meara L.B. / O'Neill J.R. / Okafor B.U. / Olson S.A. / Oo A.Y. / Ormazabal P.C. / Osorio A.L. / Pachl M.J. / Parry J.T. / Patel P.K. / Perez-Sanchez L.E. / Pevidal A.N. / Pezzuto A.P. / Philp M.M. / Pinkney T.D. / Pollok J.M. / Povey M.G. / Poza A.A. / Rajgor A.D. / Rao J.N. / Raptis D.A. / Rice H.E. / Ridgway P.F. / Rivas A.M. / Rodriguez-Sanjuan J.C. / Rogers L.J. / Da Roit A. / Rollett R.A. / Romera J.L. / Rooney S.M. / Roxo V.I. / Le Roy B. / Rubio E.E. / Ruiz C.C. / Ruiz M.L. / Ryan E.J. / Saad A.R. / Saeed S.A. / Salama H.A. / Salamah A.A. / Sampietro G.M. / Sarma D.R. / Schaffer K.B. / Schnitzbauer A.A. / Scurrah R.J. / Serevina O.L. / Serralheiro P.A. / Sewards J.M. / Shackcloth M.J. / Shaw A.V. / Sheel A.R. / Sica G.S. / De Simone V. / Singh A.A. / Singh R.P. / Skelly B.L. / Smith H.G. / Sohail A.H. / Spalding D.R. / Springford L.R. / Ssentongo A.E. / Steinkamp P.J. / Stevens K.A. / Stewart G.D. / Stylianides N.A. / Sullivan T.B. / Taher A.S. / Tamimy M.S. / Tang A.M. / Tebala G.D. / Tejero-Pintor F.J. / Thaha M.A. / Thomas A.J. / De Toma G. / La Torre F. / Torres A.J. / Townshend D.N. / Trout I.M. / Tucker S.C. / Ubhi H.K. / Vega V.A. / Velmahos G.C. / Velopulos C.G. / Viswanath Y.K. / Vivas A.A. / Wade R.G. / Wadley M.S. / Wall J.J. / Walters A.M. / Warren O.J. / Weerasinghe C.K. / Wilkin R.J. / Williams K.J. / Winter S.C. / Wormald J.C. / Wright F.L. / Xyda S.E. / Young A.L. / Youssef M.M. / Yousuf F.B. / El Youzouri H. / Zappa M.A. / Abate E. / Abdalaziz H. / Abdelkarim M. / Abdou H. / Aboelkassem-Ibrahim A. / Abuown A. / Acebes-Garcia F. / Acharya M. / Adamina M. / Addae-Boateng E. / Aftab R. / Agarwal A. / Aguilar J. / Ahmed Y. / Aitken E. / Al-Azzawi M. / Al-Embideen S. / Al-Masri M. / Al-Najjar H. / Al-Sukaini A. / Alam R. / Alderson D. / Aliyeva Z. / Aljanadi F. / Almasri M. / Alonso-Ortuno P. / Altintoprak F. / Amira G. / Amjad R. / Anania G. / Andabaka T. / Angelou D. / Annamalai S. / Annessi V. / Anthoney J. / Anwar S. / Anwer M. / Aragon-Chamizo J. / Ardito A. / Arigoni M. / Armao T. / Arminio A. / Armstrong L. / Arnaud A. / Asaad P. / Ashcroft J. / Ashmore C. / Asqalan A. / Asti E. / Aubry E. / Aytac E. / Ayuso-Herrera E. / Baeza M. / Bailon-Cuadrado M. / Bakmaz B. / Baldi C. / Baldini E. / Baldo S. / Ballabio M. / Baloyiannis I. / Baltazar G. / Bambina F. / Bandiera A. / Barlow E. / Barmasse R. / Barmpagianni C. / Baronio G. / Barra F. / Bartsch A.-M. / Basgaran A. / Basha A. / Bashkirova V. / Bastazza M. / Baumber R. / Belcher E. / Belvedere A. / Benitez-Linero I. / Bergeat D. / Bernasconi M. / Bhalla A. / Bhutiani N. / Bianco F. / Bisagni P. / Blake I. / Blanco-Colino R. / Blazquez-Martin A. / Boal M. / Bonavina L. / Bonavina G. / Bond-Smith G. / Booth K. / Borges F. / Borghi F. / Bouchagier K. / Bourke G. / Boyle E. / Brachini G. / Brain J. / Brar A. / Breckles L. / Bretagnol F. / Brixton G. / Bruzzaniti P. / Bueser T. / Burnside N. / Caballero A. / Calcerrada-Alises E. / Callahan M. / Camarero E. / Campagnaro T. / Campanelli M. / Candiani M. / Cantalejo-Diaz M. / Cao H. / Capelli P. / Capizzi V. / Carcano G. / Carissimi F. / Carlini M. / Carlucci M. / Carmichael H. / Carrasco M. / Carrillo M. / Carvello M. / Casati M. / Castoro C. / Catalan V. / Cavaleiro S. / Cellerino P. / Centinaio G. / Cernei C. / Cerro C. / Cervellera M. / Chakrabortee S. / Chamberlain S. / Chan J. / Chang G. / Chaudhry D. / Chebaro A. / Chen D. / Chetty G. / Chia Z. / Chiappini A. / Chiarugi M. / Chidambaram S. / Chiozza M. / Cholewa H. / Chong C. / Choolani-Bhojwani E. / Christoforidis D. / Chui K. / Chung C. / Cirillo B. / Citterio D. / Clermidi P. / Coccolini F. / Colletti G. / Compagnoni B. / Concepcion-Martin V. / Confalonieri M. / Connolly H. / Conso C. / Conti L. / Cooper Z. / Cordera F. / Corral J. / Costa M. / Costanzi A. / Cotsoglou C. / Cozza V. / Cuming T. / Curtis M. / Cuschieri J. / D'Agruma M. / D'Andrea G. / Daliya P. / Dare O. / Darko E. / Day A. / Dehal A. / Dehart D. / Delgado-Oliver E. / Denning M. / Desai A. / Desender L. / Dester S. / Diaz-Garcia A. / Diaz-Pena P. / Dousset B. / Doussot A. / Duchateau N. / Duff S. / Dunning J. / Duque-Mallen V. / Dziakova J. / Egan B. / Egan R. / El-Ali A. / Elfeki H. / Elhadi M. / Eljareh M. / Elkady R. / Elkhafeefi F. / Elmore U. / Elmoslemany T. / Emmerson O. / Enemosah I. / English C. / English W. / Escartin J. / Estaire-Gomez M. / Evans L. / Evans J. / Exley R. / Fabbri N. / Falco G. / Familiari P. / Fancellu A. / Farik S. / Farrell T. / Fehervari M. / Fell A. / Fernandez-Camunas A. / Fernandez-Marin R. / Fernandez-Martinez M. / Ferrara F. / Ferrari G. / Ferrero S. / Findlay L. / Fiore M. / Fiori E. / Flatman M. / Flindall I. / Flor B. / Fontana T. / Ford S. / Ford D. / Forlani S. / Francone E. / Frattaruolo C. / Frio F. / Gagliano A. / Gagliardi F. / Gahunia S. / Gaino F. / Gala T. / Galfrascoli E. / Galimberti L. / Gallagher P. / Galleano R. / Galvan-Perez A. / Gammeri E. / Ganau M. / Garces-Garcia R. / Garulli G. / Gascon-Ferrer I. / Gattolin A. / Gaujoux S. / Gentilli S. / Georgiades F. / Ghanbari A. / Ghosh D. / Giacometti M. / Giblin A.-V. / Gilbert C. / Gimenez C. / Giorgakis E. / Gipponi M. / Glen P. / Goatly G. / Gobatti D. / Godbole C. / Gohil K. / Gomez M. / Gomez-Rosado J.-C. / Gonullu E. / Gonzalez-Gonzalez E. / Gordini L. / Gracia I. / Gracia-Roche C. / Granieri S. / Green S. / Grivon M. / Grove T. / Guaglio M. / Guaitoli E. / Guglielmi A. / Guha S. / Gustavino C. / Habeeb A. / Hagger R. / Hakmi H. / Halkias C. / Hall C. / Hampton M. / Handa S. / Hansen L. / Haq I. / Harky A. / Harries R. / Harrison J. / Hasan R. / Hawari M. / Hawkin P. / Hebblethwaite B. / Henriques S. / Heritage E. / Hernandez-Juara P. / Herrero-Lopez M. / Hervieux E. / Heyd B. / Higgs S. / Hitchman L. / Ho B. / Hogan A. / Holzle F. / Hossain T. / Hurt L. / Hutchinson P. / Iacob G. / Iannone I. / Ibrahim S. / Iovino D. / Isik A. / Jafarova S. / Jamil T. / Jayaraju U. / Jenner E. / Jimenez-Higuera E. / Jimeno J. / Jones M. / Judkins N. / Kalavrezos N. / Kalidindi V. / Kalkat M. / Kamal M. / Kamphues C. / Kang C. / Kara Y. / Karam E. / Karim A. / Kashora F. / Kearney D. / Khajuria A. / Khan U. / Khan A. / Khatri C. / Kinnaman G. / Kinross J. / Kler A. / Klimopoulos S. / Kocatas A. / Kolias A. / Konigsrainer A. / Konsten J. / Kontovounisios C. / Kourdouli A. / Krishnan E. / Kristinsson S. / Kruijff S. / Kudsk-Iversen S. / Kufeji D. / Kugler N. / Kulkarni R. / Kurihara H. / Laface L. / Lakkis Z. / Lami M. / Landaluce-Olavarria A. / Lapolla P. / Lawani I. / Lawday S. / Lazaro A. / Lecolle K. / Leventoglu S. / Li Z. / Liew I. / Lisi G. / Lizzi V. / Lo T. / Lomiento D. / Longhi M. / Lostis E. / Lostoridis E. / Loubani M. / Lowy-Benoliel A. / Lucianetti A. / Luke L. / Lunevicius R. / Luraghi M. / Lye G. / Mabrouk I. / Macchi A. / MacDonald L. / Machairas N. / Madonini M. / Magowan D. / Maisonneuve E. / Majkowska A. / Majkowski L. / Mak J. / Malabarba S. / Malerba M. / Mannan S. / Manson J. / Mansuri A. / Mantoglu B. / Manu N. / Maqsood A. / Marano A. / Marchbank A. / Marcos-Santos P. / Marrano E. / Martin J. / Martin E. / Martin G. / Martin-Albo L. / Martin-Roman L. / Martinelli F. / Martinez-dePaz F. / Martinez-German A. / Martinez-Pinedo C. / Martins R. / Marwan H. / Marzi F. / Mathieu P. / Matute-Najarro M.-S. / Maw A. / Mazingi D. / Mazzaferro V. / McCanny A. / McKenzie K. / McLarty N. / McPherson I. / Medina E. / Mediratta S. / Medone M. / Mehra G. / Mele S. / Melero-Cortes L. / Mendoza-Moreno F. / Meneghini S. / Mercante G. / Merdrignac A. / Merola S. / Metallidis S. / Michel M. / Migliore M. / Mihanovic J. / Miller D. / Mingoli A. / Minto G. / Mirabella A. / Misra N. / Mitrasinovic S. / Miu V. / Moawad N. / Mochet S. / Modabber A. / Mohammad A. / Mohan M. / Moliner-Sanchez C. / Mongelli F. / Monteleone M. / Montuori M. / Moore R. / Mora-Guzman I. / Morales X. / Morales D. / Morelli L. / Morgan R. / Morris C. / Mortini P. / Mosca A. / Motter D. / Moug S. / Mukherjee S. / Najdy M. / Nakas A. / Namazov I. / Naredla P. / Nasef E. / Nassa H. / Nath R. / Navarro-Sanchez A. / Nazarian S. / Negri G. / Nehra D. / Neil-Dwyer J. / Neri J. / Newton K. / Nikaj H. / Niquen M. / Nobile S. / Nogueiro J. / Ntirenganya F. / Nugent M. / Nunez J. / Ocana J. / Okechukwu V. / Oliva-Mompean F. / Oliveira A. / Ollat D. / Onos L. / Osagie-Clouard L. / Osman K. / Ottolina J. / Ourieff J. / Outani O. / Oyewole B. / Ozben V. / Pacheco-Sanchez D. / Padilla-Valverde D. / Pai M. / Paiella S. / Paisley S. / Palini G. / Palmeri M. / Panahi P. / Parente A. / Parlanti D. / Parmar C. / Pascual A. / Patel M. / Pathak A. / Patil S. / Pattyn P. / Peckham-Cooper A. / Pedrazzani C. / Pellino G. / Peluso C. / Pereira A. / Pereira-Neves A. / Perez-Diaz M.D. / Perez-Gonzalez M. / Perez-Saborido B. / Perivoliotis K. / Perkins C. / Peros G. / Perotto O. / Perra T. / Petrone P. / Phenix G. / Picazo S. / Picon-Rodriguez R. / Piloni M. / Pingarron-Martin L. / Pinotti E. / Pisanu A. / Pizzini P. / Pockney P. / Podda M. / Podolsky D. / Poggioli G. / Pompili C. / Pontari M. / Porcu A. / Potter R. / Price C. / Pruvot F.-R. / Pujol-Muncunill R. / Puppo A. / Quante M. / Quintana-Villamandos B. / Qureshi A. / Radenkovic D. / Rakvin I. / Ramallo-Solis I. / Ramcharan S. / Ramos D. / Ramos-Bonilla A. / Ramzi J. / Rathinam S. / Rausa E. / Ravaioli M. / Ravindran S. / Raymond T. / Razik A. / Redfern J. / Reguera-Rosal J. / Rela M. / Rey-Biel J. / Rey-Valcarcel C. / Ribolla M. / Richards T. / Richmond M. / Righini E. / Rio-Gomez J. / Riyat H. / Rizvi S. / Roberts K. / Roberts M. / Robertson S. / Robertson R. / Robin-Valle A. / Rochon M. / Rojo M. / Rolli L. / Romano S. / Ross E. / Ross H. / Rossborough C. / Rottoli M. / Ruiz-Grande F. / Ruiz-Martin I. / Ruiz-Soriano M. / Ruzzenente A. / Ryska O. / Saez C. / Sagnotta A. / Sahnan K. / Sahni A. / Salim A. / Sallam I. / Salvia R. / Samadov E. / Sammarco G. / Sampaio-Alves M. / Sanchez-Arteaga A. / Sanchez-Fuentes M.-N. / Sanchez-Pelaez D. / Sanchez-Perez C. / Sanchez-Rubio M. / Sancho-Muriel J. / Sanders J. / Santero-Ramirez M.-P. / Santora T. / Santoro A. / Santos I. / Santos-Sousa H. / Sapienza P. / Sartarelli L. / Sarveswaran J. / Sasia D. / Saudemont A. / Saudi-Moro S. / Saxena S. / Saxena D. / Sayasneh A. / Scalabre A. / Schache A. / Schiavina R. / Schineis C. / Schreckenbach T. / Scorza A. / Scott L. / Seegert S. / Seguin-Givelet A. / Senent-Boza A. / Seymour K. / Shabana A. / Shah K. / Shah J. / Shah P. / Shah S. / Shakir T. / Shalaby M. / Shankar S. / Shaw R. / Shehata S. / Shenfine A. / Sheridan K. / Sherief A. / Sherief M. / Sherif M. / Shinkwin M. / Shu S. / Siaw-Acheampong K. / Sileri P. / Singh A. / Singh S. / Sinha S. / Sinha D. / Siragusa L. / Sivaprakasam R. / Sivayoganathan S. / Smillie R. / Smith C. / Smith A. / Sochorova D. / Soggiu F. / Sohrabi C. / Solari F. / Solli P. / Soreide K. / Spinelli A. / Spoletini D. / Spriano G. / Sravanam S. / Ssentongo P. / Stanger S. / Stavroulias D. / Steel B. / Stella M. / Stewart R. / Stringer S. / Sulen N. / Sundar S. / Sundhu M. / Suri A. / Syed A. / Szatmary P. / Tabiri S. / Tadross D. / Taglietti L. / Tansey R. / Tartaglia D. / Tawheed A. / Tayeh S. / Teles T. / Testa V. / Tewari N. / Thoenissen P. / Thomas K. / Thomin A. / Thrush J. / Tierney S. / Tiwari A. / Toh S. / Toledo E. / Tonini V. / Torkington J. / Torquati A. / Torzilli G. / Totty J. / Tourountzi P. / Tousidonis M. / Townend P. / Townsend C. / Trompeter A. / Trotta F. / Truant S. / Trujillo-Diaz J. / Turco C. / Turrado-Rodriguez V. / Turri G. / Tustin H. / Tyler J. / Tzedakis S. / Tzovaras G. / Uittenbogaart M. / Ullah R. / Urban S. / Urbani A. / Usai A. / Vaccarella G. / Valdes-Hernandez J. / Valsecchi L. / Vashisht R. / Vazquez-Fernandez A. / Venn M. / Vera-Mansilla C. / Vergari R. / Vescio G. / Vidya R. / Vieira P. / Vijay V. / Vimalachandran D. / Violante T. / Volpe A. / Vovola F. / Vulliamy P. / Wall R. / Wallwork K. / Ward A. / Warwick D. / Waseem S. / Weaver H. / Wells F. / Wen J. / West R. / Whitehall E. / Wild L. / Wilkins A. / Williams G. / Williams M. / Winnand P. / Wong K. / Worku D. / Wright N. / Yalamanchili S. / Yershov D. / Yildiz A. / Young R. / Yurttas C. / Zadegan F. / Zafar N. / Zakaria R. / Zambon M. / Zanini N. / Zarate A. / Zerbib P. / Zizzo M. / Zmora O. / Zonta S. / van Berge Henegouwen M.I. / van der Plas W.Y. / Ali I.A.M. / Bakri N.A.C. / Bauset J.C.C. / Abou Chaar M.K. / Marino Cosentino L.M. / Gomez Diaz C.J. / Garcia Galocha J.L. / de Gheldere C.A. / Ataide Gomes G.M. / Beltran de Heredia J. / Blazer III D.G. / Nugent III W.C. / Ali karar A.A. / Borja De Lacy F. / Blas Laina J.L. / Shane Lester M.J. / Liyanage A.S.D. / Al Maadany F.S. / De Marchi J.A. / Ramos-De la Medina A. / Mithany R.H.M. / Sanchez del Pueblo C. / van Ramshorst G.H. / De Salas M.M. / De Souza A.C. / Dolores Del Toro M. / Archer J.E. / Odeh A. / Erridge S. / Salem H.K. / Jones G.P. / Gardner A. / Tripathi S.S. / Gregg A. / Jeganathan R. / Siddique M.H. / Lombardi C.P. / Martin B. / Leo C.A. / Dass D. / Di Franco G. / Jiao L.R. / Mari G.M. / Capitan-Morales L.-C. / Connelly T.M. / Alanbuki A. / De Virgilio A. / Schilling C. / San Miguel Mendez C. / Kulkarni G. / Nizami K. / Walsh S. / Dean H. / Ruiz-Marin M. / Houston R. / Trompetto M. / Chrastek D. / Kouritas V. / Cannoletta M. / Rosato F. / Kaushal M.V. / Costa P.M. / Elkadi H.H. / Johnstone J.R. / Irvine E. / Alvarez M.R. / Corbellini C. / Venkatesan G.S. / Mateo-Sierra O. / Martinez-Perez C. / Serrano Gonzalez J. / Hernandez Bartolome M.A. / Diaz Perez D. / Gutierrez Samaniego M. / Galindo Jara P. / Sharma N. / Smart N.J. / Keller D.S.

    an international cohort study

    2020  

    Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

    Abstract Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p<0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
    Keywords Adult ; Aged ; Betacoronavirus ; Coronavirus Infections ; Elective Surgical Procedures ; Emergency Medical Services ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia ; Viral ; Postoperative Complications ; Respiratory Tract Diseases ; Retrospective Studies ; Surgical Procedures ; Operative ; Young Adult ; covid19
    Subject code 610 ; 616
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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