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  1. Article: Dépôts immuns le long des basales tubulaires au cours de la néphropathie à BK virus.

    Belgaid, Youcef Chafik / Moktefi, Anissa

    Annales de pathologie

    2024  

    Title translation Tubular basement membrane immune deposits during BK virus nephropathy.
    Language French
    Publishing date 2024-02-08
    Publishing country France
    Document type Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2024.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Atteinte glomérulaire au cours de la néphropathie à BK virus.

    Belgaid, Youcef Chafik / Moktefi, Anissa

    Annales de pathologie

    2023  Volume 43, Issue 5, Page(s) 427–428

    Title translation Glomerular injury during BK virus nephropathy.
    MeSH term(s) Humans ; BK Virus ; Kidney Diseases/etiology ; Kidney Transplantation/adverse effects ; Kidney Glomerulus ; Tumor Virus Infections/complications ; Tumor Virus Infections/diagnosis ; Polyomavirus Infections/complications ; Polyomavirus Infections/diagnosis ; Immunosuppressive Agents
    Chemical Substances Immunosuppressive Agents
    Language French
    Publishing date 2023-02-22
    Publishing country France
    Document type Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2023.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Late Kidney Graft Dysfunction Related to JC Virus Nephropathy.

    Bensaou, Sarah / Morel, Antoine / Matignon, Marie / Stehle, Thomas / Moktefi, Anissa

    Kidney medicine

    2024  Volume 6, Issue 5, Page(s) 100807

    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Editorial
    ISSN 2590-0595
    ISSN (online) 2590-0595
    DOI 10.1016/j.xkme.2024.100807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Belatacept inhibit human B cell germinal center development in immunodeficient mice.

    Samson, Chloé / Thiolat, Allan / Moktefi, Anissa / Cohen, José L / Pilon, Caroline / Grimbert, Philippe

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 13816

    Abstract: The humoral response mediated by alloantibodies directed against donor HLA molecules (DSAs) is one of the main causes of graft loss in kidney transplantation. Understanding the pathophysiology leading to humoral kidney rejection as the development of ... ...

    Abstract The humoral response mediated by alloantibodies directed against donor HLA molecules (DSAs) is one of the main causes of graft loss in kidney transplantation. Understanding the pathophysiology leading to humoral kidney rejection as the development of therapeutic tools is therefore a main objective in the field of solid organ transplantation and necessitate adapted experimental models. Among the immunosuppressive agents used in renal transplantation, belatacept, a fusion protein targeting T costimulatory molecules has shown its ability to prevent more efficiently the secretion of DSA by different mechanisms including a direct action on plasma cells but also on B lymphocytes and follicular helper T lymphocytes (Tfh) cooperation. This cellular cooperation occurs within germinal centers (GC), the seat of B lymphocytes differentiation. Here, we aimed to develop a dedicated mouse model in which human GC would be functional to study the effect of belatacept on GC formation and the ability of B lymphocytes to secrete immunoglobulin. We next demonstrate that belatacept inhibits the formation of these GCs, by inhibiting the frequency of Tfh and B lymphocytes. This alters the B maturation and therefore the generation of plasma cells and consequently, immunoglobulin secretion.
    MeSH term(s) Humans ; Animals ; Mice ; Abatacept/pharmacology ; Germinal Center ; B-Lymphocytes ; Immunosuppressive Agents/pharmacology ; Plasma Cells
    Chemical Substances Abatacept (7D0YB67S97) ; Immunosuppressive Agents
    Language English
    Publishing date 2023-08-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-40700-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Tolvaptan to prevent calcium oxalate crystal deposition in the kidney allograft after kidney transplantation for primary hyperoxaluria.

    Stehlé, Thomas / Letavernier, Emmanuel / Joher, Nizar / Mesnard, Laurent / Moktefi, Anissa / Matignon, Marie

    Kidney international

    2023  Volume 104, Issue 2, Page(s) 398

    MeSH term(s) Humans ; Kidney Transplantation/adverse effects ; Tolvaptan/therapeutic use ; Calcium Oxalate ; Hyperoxaluria, Primary ; Kidney ; Calcinosis ; Allografts
    Chemical Substances Tolvaptan (21G72T1950) ; Calcium Oxalate (2612HC57YE)
    Language English
    Publishing date 2023-07-20
    Publishing country United States
    Document type Letter
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2023.05.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Infections and Collapsing Glomerulopathy.

    Moktefi, Anissa / Audard, Vincent / El Karoui, Khalil

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2020  Volume 76, Issue 4, Page(s) 600–601

    MeSH term(s) Adult ; Curriculum ; Humans ; Infections ; Kidney Diseases/diagnosis ; Kidney Diseases/etiology ; Kidney Glomerulus
    Keywords covid19
    Language English
    Publishing date 2020-06-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2020.05.016
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  7. Article: Renal Diseases Associated with Hematologic Malignancies and Thymoma in the Absence of Renal Monoclonal Immunoglobulin Deposits.

    Morel, Antoine / Meuleman, Marie-Sophie / Moktefi, Anissa / Audard, Vincent

    Diagnostics (Basel, Switzerland)

    2021  Volume 11, Issue 4

    Abstract: In addition to kidney diseases characterized by the precipitation and deposition of overproduced monoclonal immunoglobulin and kidney damage due to chemotherapy agents, a broad spectrum of renal lesions may be found in patients with hematologic ... ...

    Abstract In addition to kidney diseases characterized by the precipitation and deposition of overproduced monoclonal immunoglobulin and kidney damage due to chemotherapy agents, a broad spectrum of renal lesions may be found in patients with hematologic malignancies. Glomerular diseases, in the form of paraneoplastic glomerulopathies and acute kidney injury with various degrees of proteinuria due to specific lymphomatous interstitial and/or glomerular infiltration, are two major renal complications observed in the lymphoid disorder setting. However, other hematologic neoplasms, including chronic lymphocytic leukemia, thymoma, myeloproliferative disorders, Castleman disease and hemophagocytic syndrome, have also been associated with the development of kidney lesions. These renal disorders require prompt recognition by the clinician, due to the need to implement specific treatment, depending on the chemotherapy regimen, to decrease the risk of subsequent chronic kidney disease. In the context of renal disease related to hematologic malignancies, renal biopsy remains crucial for accurate pathological diagnosis, with the aim of optimizing medical care for these patients. In this review, we provide an update on the epidemiology, clinical presentation, pathophysiological processes and diagnostic strategy for kidney diseases associated with hematologic malignancies outside the spectrum of monoclonal gammopathy of renal significance.
    Language English
    Publishing date 2021-04-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics11040710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Anti-CD38 therapy for PLA2R-positive membranous nephropathy resistant to conventional immunosuppression.

    Stehlé, Thomas / Grimbert, Philippe / Remy, Philippe / Moktefi, Anissa / Audard, Vincent / El Karoui, Khalil

    Kidney international

    2022  Volume 101, Issue 2, Page(s) 416–418

    MeSH term(s) Glomerulonephritis, Membranous/drug therapy ; Humans ; Immunosuppression Therapy ; Receptors, Phospholipase A2
    Chemical Substances Receptors, Phospholipase A2
    Language English
    Publishing date 2022-01-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2021.11.001
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  9. Article ; Online: IgG4-related disease and small lymphocytic lymphoma.

    Moktefi, Anissa / Mulé, Sébastien / Joher, Nizar / Blanc-Durand, Paul / Oniszczuk, Julie / Matignon, Marie / Le Bras, Fabien / El Karoui, Khalil

    QJM : monthly journal of the Association of Physicians

    2023  Volume 116, Issue 7, Page(s) 523–524

    MeSH term(s) Humans ; Leukemia, Lymphocytic, Chronic, B-Cell ; Immunoglobulin G4-Related Disease/complications ; Immunoglobulin G4-Related Disease/diagnosis
    Language English
    Publishing date 2023-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcad019
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  10. Article: CD44 staining in parietal epithelial cells and early steroid response in patients with minimal change disease.

    Morel, Antoine / Remy, Philippe / Sakhi, Hamza / El Karoui, Khalil / Sahali, Dil / Audard, Vincent / Moktefi, Anissa

    Clinical kidney journal

    2023  Volume 16, Issue 8, Page(s) 1355–1358

    Language English
    Publishing date 2023-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad072
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