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  1. AU="Molina Ruiz, Juan Carlos"
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  1. Article: The Role of Anesthetic Drugs and Statins in Prostate Cancer Recurrence: Starting at the Actual Knowledge and Walking through a New Paradigm.

    Raigon Ponferrada, Aida / Molina Ruiz, Juan Carlos / Romero Molina, Salvador / Rodriguez Garcia, Verónica / Guerrero Orriach, Jose Luis

    Cancers

    2023  Volume 15, Issue 11

    Abstract: Prostate cancer has become a major health problem in men. Its incidence is increasing as the average age of the affected population tends to be higher. Of all the possible treatments, surgery is the gold standard in its treatment. Surgery produces a ... ...

    Abstract Prostate cancer has become a major health problem in men. Its incidence is increasing as the average age of the affected population tends to be higher. Of all the possible treatments, surgery is the gold standard in its treatment. Surgery produces a deregulation in the immune system that can favour the development of distant metastases. Different anesthetic techniques have raised the hypothesis that different anesthetic drugs influence tumor recurrence and prognosis. Some mechanisms are beginning to be understood by which halogenated agents in cancer patients and the use of opioids may negatively affect patients. In this document, we group together all the available evidence on how the different anesthetic drugs affect tumor recurrence in prostate cancer.
    Language English
    Publishing date 2023-06-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15113059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: COVID-19 pandemic and nurse teaching: Our experience.

    Molina Ruiz, Juan Carlos / Guerrero Orriach, Jose Luis / Bravo Arcas, Maria Luisa / Montilla Sans, Angela / Escano Gonzalez, Rocio

    World journal of clinical cases

    2022  Volume 10, Issue 8, Page(s) 2657–2659

    Abstract: In this letter to the editor, we would like to show in our hospital how our nurse team manage formation during coronavirus disease 2019 pandemic. ...

    Abstract In this letter to the editor, we would like to show in our hospital how our nurse team manage formation during coronavirus disease 2019 pandemic.
    Language English
    Publishing date 2022-01-16
    Publishing country United States
    Document type Journal Article
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v10.i8.2657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Breast Cancer and Anaesthesia: Genetic Influence.

    Raigon Ponferrada, Aida / Guerrero Orriach, Jose Luis / Molina Ruiz, Juan Carlos / Romero Molina, Salvador / Gómez Luque, Aurelio / Cruz Mañas, Jose

    International journal of molecular sciences

    2021  Volume 22, Issue 14

    Abstract: Breast cancer is the leading cause of mortality in women. It is a heterogeneous disease with a high degree of inter-subject variability even in patients with the same type of tumor, with individualized medicine having acquired significant relevance in ... ...

    Abstract Breast cancer is the leading cause of mortality in women. It is a heterogeneous disease with a high degree of inter-subject variability even in patients with the same type of tumor, with individualized medicine having acquired significant relevance in this field. The clinical and morphological heterogeneity of the different types of breast tumors has led to a diversity of staging and classification systems. Thus, these tumors show wide variability in genetic expression and prognostic biomarkers. Surgical treatment is essential in the management of these patients. However, the perioperative period has been found to significantly influence survival and cancer recurrence. There is growing interest in the pro-tumoral effect of different anaesthetic and analgesic agents used intraoperatively and their relationship with metastatic progression. There is cumulative evidence of the influence of anaesthetic techniques on the physiopathological mechanisms of survival and growth of the residual neoplastic cells released during surgery. Prospective randomized clinical trials are needed to obtain quality evidence on the relationship between cancer and anaesthesia. This document summarizes the evidence currently available about the effects of the anaesthetic agents and techniques used in primary cancer surgery and long-term oncologic outcomes, and the biomolecular mechanisms involved in their interaction.
    MeSH term(s) Anesthetics/adverse effects ; Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Female ; Humans ; Neoplasm Recurrence, Local/chemically induced ; Neoplasm Recurrence, Local/genetics
    Chemical Substances Anesthetics
    Language English
    Publishing date 2021-07-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22147653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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