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  1. Article ; Online: Correction to: Women with a predisposition for diabetes have an increased risk of pregnancy complications, especially in combination with pregestational overweight.

    Moll, Ulrika / Olsson, Håkan / Landin-Olsson, Mona

    BMC pregnancy and childbirth

    2020  Volume 20, Issue 1, Page(s) 116

    Abstract: Following publication of the original article [1], we have been notified by the author that the age of women from the Result section was incorrectly tagged as references. ...

    Abstract Following publication of the original article [1], we have been notified by the author that the age of women from the Result section was incorrectly tagged as references.
    Language English
    Publishing date 2020-02-19
    Publishing country England
    Document type Journal Article ; Published Erratum
    ISSN 1471-2393
    ISSN (online) 1471-2393
    DOI 10.1186/s12884-020-2803-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Women with a predisposition for diabetes have an increased risk of pregnancy complications, especially in combination with pregestational overweight.

    Moll, Ulrika / Olsson, Håkan / Landin-Olsson, Mona

    BMC pregnancy and childbirth

    2020  Volume 20, Issue 1, Page(s) 74

    Abstract: Background: Overweight and gestational diabetes are risk factors for pregnancy complications. We hypothesized that the metabolic impact of overweight on pregnancy outcome, would be different if it was combined with a predisposition for diabetes. The aim ...

    Abstract Background: Overweight and gestational diabetes are risk factors for pregnancy complications. We hypothesized that the metabolic impact of overweight on pregnancy outcome, would be different if it was combined with a predisposition for diabetes. The aim of this study was to compare the outcome of pregnancies in women with diabetes diagnosed later in life, to the outcome of pregnancies of women who did not develop diabetes.
    Methods: Women in a population-based cohort who also were registered in the Swedish Medical Birth Registry (n = 4738) were included. A predisposition for diabetes (GDM or diabetes after pregnancy) was found in 455 pregnancies. The number of pregnancies with maternal BMI ≥ 25 kg/m
    Results: Pregnancies with normal maternal BMI ≤25 kg/m
    Conclusions: In pregnancy, there is an increased frequency of LGA, macrosomia and caesarean section if the woman has a predisposition for diabetes. The frequency of overweight young women is increasing, and it is urgent to identify pregnant women with a predisposition to diabetes. How to distinguish the women with the highest risk for adverse pregnancy outcome and the highest risk of future disease, remains to be studied.
    MeSH term(s) Adult ; Aged ; Diabetes Complications ; Diabetes, Gestational/epidemiology ; Disease Susceptibility/complications ; Female ; Humans ; Middle Aged ; Overweight/complications ; Pregnancy ; Pregnancy Complications/epidemiology ; Pregnancy Complications/etiology ; Pregnancy Outcome/epidemiology ; Registries ; Retrospective Studies ; Risk Factors ; Sweden/epidemiology
    Language English
    Publishing date 2020-02-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059869-5
    ISSN 1471-2393 ; 1471-2393
    ISSN (online) 1471-2393
    ISSN 1471-2393
    DOI 10.1186/s12884-020-2741-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Impact of Pregestational Weight and Weight Gain during Pregnancy on Long-Term Risk for Diseases.

    Moll, Ulrika / Olsson, Håkan / Landin-Olsson, Mona

    PloS one

    2017  Volume 12, Issue 1, Page(s) e0168543

    Abstract: Objective: The aim of this study was to analyse the impact of maternal BMI at start of pregnancy and maternal weight gain during pregnancy on the risk of various diseases later in life.: Methods: In a population-based cohort from southern Sweden, ... ...

    Abstract Objective: The aim of this study was to analyse the impact of maternal BMI at start of pregnancy and maternal weight gain during pregnancy on the risk of various diseases later in life.
    Methods: In a population-based cohort from southern Sweden, women with at least one delivery registered in the Swedish Medical Birth Register ten or more years before answering a health questionnaire were identified (n = 13,608). Complete data were found in 3,539 women.
    Results: Women with BMI >25 at start of pregnancy had increased risk of developing obesity (OR 21.9), diabetes (OR 6.4), cardiac disease (OR 2.7), endocrine diseases (OR 2.3), and other morbidity (OR 1.4), compared with women of normal weight. A high weight gain (>15 kg) during pregnancy was associated to later risk of overweight (OR 2.0) and obesity (OR 2.2), but not diabetes, cardiac disease, or endocrine diseases. A positive association was found between low weight gain and the risk of developing psychiatric disorders (OR 1.6).
    Conclusions: A high BMI at start of pregnancy significantly increased the risk of several diseases later in life. However, a high weight gain during pregnancy was only significant for future overweight and obesity. These findings have implications for both pregestational intervention and post gestational follow up of obese and overweight women.
    MeSH term(s) Adult ; Body Mass Index ; Body Weight ; Diabetes, Gestational ; Female ; Humans ; Obesity/complications ; Overweight/complications ; Pregnancy ; Pregnancy Complications ; Registries ; Retrospective Studies ; Risk Factors ; Surveys and Questionnaires ; Sweden ; Weight Gain ; Young Adult
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0168543
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pregnancy outcome in women with gestational diabetes - A longitudinal study of changes in demography and treatment modalities.

    Moll, Ulrika / Landin-Olsson, Mona / Nilsson, Charlotta / Ursing, Dag / Strevens, Helena

    Acta obstetricia et gynecologica Scandinavica

    2019  Volume 99, Issue 3, Page(s) 333–340

    Abstract: Introduction: Gestational diabetes is on the rise and demographics are changing in many countries due to increased migration. Simultaneously, the treatment of gestational diabetes in our clinic has shifted towards metformin with substantially less ... ...

    Abstract Introduction: Gestational diabetes is on the rise and demographics are changing in many countries due to increased migration. Simultaneously, the treatment of gestational diabetes in our clinic has shifted towards metformin with substantially less insulin treatment. The aim was to study the impact of these changes on metabolic control and pregnancy outcome by comparing women diagnosed with gestational diabetes during 2012-2013 and 2016-2017.
    Material and methods: Our universal Oral Glucose Tolerance Test screening program for gestational diabetes diagnosed 199 women with singleton pregnancies during 2012-2013 and 203 during 2016-2017. Treatment and achieved metabolic control in the two different time periods were compared. Pregnancy outcome data related to gestational diabetes were retrieved from case notes and compared between the different time periods.
    Results: When comparing results from 2016-2017 with 2012-2013 there was no difference in maternal weight or weight gain. There was a higher frequency of heredity (52.6 vs 35.4%; P = 0.001) and non-Scandinavian ethnicity (46.5 vs 33.8%; P = 0.011).The frequency of smoking during pregnancy was significantly lower (2.6 vs 7.7%; P = 0.023) There was an improved metabolic control as measured by median glucose in 2016-2017 compared with 2012-2013 (5.8 vs 6.2 mmol/L; P < 0.001). Insulin was less frequently used in 2016-2017 than in 2012-2013 (32.5 vs 44.7%; P = 0.012). There was a significant increase in the use of metformin (14.8 vs 0%; P < 0.001). There were no differences regarding the frequency of large-for-gestational-age infants (8.2% vs 7.3%; P = 0.762) or macrosomia (16.3 vs 15.1%; P = 0.745), median birthweight (3510 vs 3521; P = 0.879), frequency of cesarean section (28.1 vs 27.8%; P = 0.951) or Apgar scores at 10 minutes (10 [3-10] vs 10 [7-10]; P = 0.290).
    Conclusions: In an increasing but changing population of gestational diabetes women in our region, with more hereditary and non-Scandinavian origins, but with fewer smokers, metabolic control has improved with maintained favorable pregnancy outcomes, with more frequent use of metformin and substantially less use of insulin treatment.
    MeSH term(s) Adult ; Demography ; Diabetes, Gestational/diagnosis ; Diabetes, Gestational/epidemiology ; Diabetes, Gestational/mortality ; Diabetes, Gestational/prevention & control ; Female ; Humans ; Hypoglycemic Agents/administration & dosage ; Infant, Newborn ; Longitudinal Studies ; Pregnancy ; Pregnancy Outcome ; Prenatal Care ; Sweden/epidemiology
    Chemical Substances Hypoglycemic Agents
    Language English
    Publishing date 2019-12-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80019-3
    ISSN 1600-0412 ; 0001-6349
    ISSN (online) 1600-0412
    ISSN 0001-6349
    DOI 10.1111/aogs.13758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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