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Article ; Online: Exploring p53 protein expression and its link to TP53 mutation in myelodysplasia-related malignancies-Interpretive challenges and potential field of applications.

Bedekovics, Judit / Madarász, Kristóf / Mokánszki, Attila / Molnár, Sarolta / Mester, Ágnes / Miltényi, Zsófia / Méhes, Gábor

Histopathology

2024

Abstract: Aims: TP53 alterations have a significant prognostic effect in myeloid neoplasms. Our objective was to investigate the TP53 gene mutation status, p53 protein expression and their relationship in dysplasia-related myeloid neoplasms with varying levels of ...

Abstract	Aims: TP53 alterations have a significant prognostic effect in myeloid neoplasms. Our objective was to investigate the TP53 gene mutation status, p53 protein expression and their relationship in dysplasia-related myeloid neoplasms with varying levels of myeloblast counts. Methods and results: A total of 76 bone marrow biopsy samples with different blast counts were analysed. Total and strong (3+) p53 expression was determined. Dual immunohistochemical staining was performed to determine the cell population associated with p53 expression. NGS analysis was performed using the Accel-Amplicon Comprehensive TP53 panel. Both p53 expression and TP53 VAF showed a significant correlation with the myeloblast ratio (P < 0.0001); however, p53 expression was also present in other cell lineages. The VAF value exhibited a significant correlation with p53 expression. A high specificity (0.9800) was observed for TP53 mutation using the ≥ 10% strong (3+) p53 cut-off value, although the sensitivity (0.4231) was low. Conclusions: Strong (3+) p53 expression using a ≥ 10% cut-off value accurately predicts TP53 mutation but does not reveal the allelic state. The p53 expression is significantly influenced by myeloblast count, and histological interpretation should consider the presence of intermixed non-neoplastic marrow cells with varying physiological p53 expression.
Language	English
Publishing date	2024-04-04
Publishing country	England
Document type	Journal Article
ZDB-ID	131914-0
ISSN	1365-2559 ; 0309-0167
ISSN (online)	1365-2559
ISSN	0309-0167
DOI	10.1111/his.15185
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Article ; Online: Loss of Uncoupling Protein 1 Expression in the Subcutaneous Adipose Tissue Predicts Childhood Obesity.

Gyurina, Katalin / Yarmak, Mariia / Sasi-Szabó, László / Molnár, Sarolta / Méhes, Gábor / Röszer, Tamás

International journal of molecular sciences

2023 Volume 24, Issue 23

Abstract: Stimulation of thermogenesis by inducing uncoupling protein 1 (UCP1) expression in adipocytes is thought to promote weight loss by increasing energy expenditure, and it is postulated that the human newborn has thermogenic subcutaneous fat depots. However, ...

Abstract	Stimulation of thermogenesis by inducing uncoupling protein 1 (UCP1) expression in adipocytes is thought to promote weight loss by increasing energy expenditure, and it is postulated that the human newborn has thermogenic subcutaneous fat depots. However, it remains unclear whether a relevant number of UCP1-expressing (UCP1
MeSH term(s)	Child ; Child, Preschool ; Humans ; Infant, Newborn ; Adipose Tissue/metabolism ; Pediatric Obesity/genetics ; Pediatric Obesity/metabolism ; Subcutaneous Fat/metabolism ; Uncoupling Protein 1/genetics ; Uncoupling Protein 1/metabolism
Chemical Substances	Uncoupling Protein 1 ; UCP1 protein, human
Language	English
Publishing date	2023-11-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms242316706
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Article ; Online: Grade Group accuracy is improved by extensive prostate biopsy sampling, but unrelated to prostatectomy specimen sampling or use of immunohistochemistry.

Korpás, Kristóf Levente / Beke, Lívia / Varga, Dániel / Bidiga, László / Méhes, Gábor / Molnár, Sarolta

Pathology oncology research : POR

2023 Volume 29, Page(s) 1611157

Abstract: Assessing the accurate Grade Group of a prostate needle biopsy specimen is essential for choosing the adequate therapeutic modality for prostate cancer patients. However, it is well-known that biopsy Grade Group tends to up- or downgrade significantly at ...

Abstract	Assessing the accurate Grade Group of a prostate needle biopsy specimen is essential for choosing the adequate therapeutic modality for prostate cancer patients. However, it is well-known that biopsy Grade Group tends to up- or downgrade significantly at radical prostatectomy. We aimed to investigate the correlation between accuracy and biopsy core number, performed immunohistochemical staining (IHC) or prostatectomy specimen sampling, with the latest also being correlated with higher detection rates of adverse pathological features, e.g., positive surgical margins, higher pathological stage or presence of perineural invasion (PnI status). The study cohort consisted of 315 consecutive patients diagnosed with prostate adenocarcinoma via transrectal ultrasound-guided needle biopsy who later underwent radical prostatectomy. We grouped and compared patients based on Grade Group accuracy, presence of IHC on biopsy, margin status, pathological stage, and PnI status. Inter-observer reproducibility was also calculated. Statistical analyzes included ANOVA, Tukey's multiple comparisons
MeSH term(s)	Male ; Humans ; Prostate/surgery ; Prostate/pathology ; Immunohistochemistry ; Reproducibility of Results ; Predictive Value of Tests ; Biopsy ; Prostatectomy ; Prostatic Neoplasms/pathology ; Neoplasm Staging
Language	English
Publishing date	2023-06-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1375979-6
ISSN	1532-2807 ; 1219-4956
ISSN (online)	1532-2807
ISSN	1219-4956
DOI	10.3389/pore.2023.1611157
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Article: Comparison of pre-mortem 2D-3D ultrasound examination to post-mortem micro-CT of carotid arteries - first experiences.

Szegedi, István / Szabó, Dániel András / Emri, Miklós / Béresova, Mónika / Nagy, Mariann / Molnár, Sarolta / Nagy, Attila / Berényi, Ervin / Oláh, László / Csiba, László

Ideggyogyaszati szemle

2024 Volume 77, Issue 1-2, Page(s) 13–20

Abstract: Background and purpose: ... A prerequisite for the treatment of carotid atherosclerosis is the accurate measurement of the stenosis, that is most commonly evaluated by duplex ultrasonography. In this study, we aimed to verify the reliability of 2D and 3D ...

Title translation	Carotis artériák premortem 2D-3D ultrahangvizsgálatának és post mortem mikro-CT-vizsgálatának összehasonlítása – első tapasztalataink.
Abstract	Background and purpose: A prerequisite for the treatment of carotid atherosclerosis is the accurate measurement of the stenosis, that is most commonly evaluated by duplex ultrasonography. In this study, we aimed to verify the reliability of 2D and 3D ultrasonography, comparing the data to results of post-mortem micro-CT examination. . Methods: Neurological patients with any life-threatening, presumably fatal neurological disease were enrolled. Ultrasound examinations were performed with a Philips Epiq 5G machine, using a VL13-5 broadband linear volume array transducer. Plaque length, diameter and vessel area reduction (stenosis) were calculated using the 2D images. Finally, the stenosis was reassessed using automatized, 3D application as well. After the death of the patient, autopsy was performed, during which the previously examined carotid artery was removed. The samples were examined with micro-CT. Similar to the ultrasound examination, plaque length, diameter and vessel area reduction (stenosis) were determined. . Results: Ten vessels of seven patients were eligible for complex comparison. Plaque diameter and length measured by CT did not correlate with the ultrasound data. CT-measured axial plaque and vessel areas showed no correlation with ultrasound results either. While determining the strength of correlation between stenoses measured by the different modalities, significant correlation was found between the results measured by ultrasound (2D) and CT (Pearson r: 0.902, P<0.001). . Conclusion: Three-dimensional ultrasound analysis is a spectacular method for examining carotid plaques, as it can assist in a more detailed evaluation of the plaque morphology and composition, thereby identifying plaques with a particularly high risk of stroke. Micro-CT is an excellent tool for the exact determination of calcified plaque areas, but ultrasound images are not suitable yet for such a precise examination due to acoustic shadowing and artifacts. .
MeSH term(s)	Humans ; X-Ray Microtomography ; Constriction, Pathologic ; Reproducibility of Results ; Imaging, Three-Dimensional/methods ; Carotid Arteries/diagnostic imaging ; Ultrasonography/methods ; Autopsy ; Carotid Stenosis/diagnosis
Language	English
Publishing date	2024-02-06
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	2240317-6
ISSN	0019-1442
ISSN	0019-1442
DOI	10.18071/isz.77.0013
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Article: A Case of Therapy-related Acute Myeloid Leukemia Following Treatment with 5-Fluorouracil.

Pinczés, László / Molnár, Sarolta / Telek, Béla / Illés, Árpád

Cureus

2018 Volume 10, Issue 12, Page(s) e3769

Abstract: Therapy-related acute myeloid leukemia (t-AML) is most frequently observed after the use of alkylating agents and topoisomerase II inhibitors and is associated with the frequent occurrence of high-risk karyotypes, poor prognosis, and distinct clinical ... ...

Abstract	Therapy-related acute myeloid leukemia (t-AML) is most frequently observed after the use of alkylating agents and topoisomerase II inhibitors and is associated with the frequent occurrence of high-risk karyotypes, poor prognosis, and distinct clinical behavior. Therefore, identifying therapy-related causation among patients with newly diagnosed acute leukemia is of great interest. We report the case of a patient who developed therapy-related acute myeloid leukemia after exposure to antimetabolite chemotherapy and emphasize the importance of identifying genetic alterations when the possibility of a therapy-related origin arises.
Language	English
Publishing date	2018-12-24
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.3769
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Article ; Online: Hemangioma of the uterine cervix: report of four cases and review of the literature.

Csécsei, Károly / Csehely, Szilvia / Póka, Róbert / Zádori, Zoltán / Németh, István / Ringelhan, Birgit / Molnár, Sarolta / Jakab, Attila

Orvosi hetilap

2022 Volume 163, Issue 5, Page(s) 187–194

Abstract: Összefoglaló. A haemangioma a női nemi szervekben viszonylag ritkán, a méhnyakban pedig még ritkábban fordul elő. Kis mérete és szegényes megjelenése miatt elkerülheti a figyelmet, előfordul azonban, hogy műtéti ellátást igénylő vérzést okoz. Az évek ... ...

Title translation	Haemangioma a méhnyakban: 4 eset ismertetése és irodalmi áttekintés.
Abstract	Összefoglaló. A haemangioma a női nemi szervekben viszonylag ritkán, a méhnyakban pedig még ritkábban fordul elő. Kis mérete és szegényes megjelenése miatt elkerülheti a figyelmet, előfordul azonban, hogy műtéti ellátást igénylő vérzést okoz. Az évek során 4 esetben (ebből 2 esetben terhesség alatt) diagnosztizáltunk méhnyak-haemangiomát (2 esetben cervicalis intraepithelialis carcinomával társulva), melyeknek ismertetjük változatos tüneteit, kolposzkópos megjelenését és a diagnózist biztosító szövettani (immunhisztokémiai) illusztrációit, valamint a képlet terhesség alatti fejlődésének kolposzkópos monitorizálását. 2 esetben capillaris (cavernosus) haemangiomát, 2 esetben arteriovenosus malformatiót igazoltunk. Az általunk hozzáférhető szakirodalomban nem találtunk magyar szerző(k)től beszámolót erről a cervicalis lokalizációjú, ritka, jóindulatú, de gyakran veszélyes vascularis daganatról. Orv Hetil. 2022; 163(5): 187-194. Summary. Hemangioma is relatively rare in the female genital organs and even less common in the uterine cervix. Its small size and poor appearance often result in a missed diagnosis, but it may cause bleeding that requires surgery. Over the years, we have confirmed the diagnosis of cervical hemangioma in 4 cases including two in pregnancy. 2 cases were associated with cervical intraepithelial neoplasia. This case report describes the symptoms, colposcopic appearance, and histological characteristics including immunohistochemical findings, and the colposcopic monitoring of development of the condition during pregnancy. In 2 cases, a capillary (cavernous) hemangioma, in 2 cases an arteriovenous malformation was diagnosed. We did not find any report from Hungarian author(s) about this rare, benign, but often dangerous vascular tumor with cervical localization. Orv Hetil. 2022; 163(5): 187-194.
MeSH term(s)	Cervical Intraepithelial Neoplasia ; Cervix Uteri ; Female ; Hemangioma/diagnosis ; Hemangioma, Cavernous ; Humans ; Pregnancy ; Uterine Cervical Neoplasms/diagnosis
Language	Hungarian
Publishing date	2022-01-30
Publishing country	Hungary
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2022.32317
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Article ; Online: Discrepancies between clinical and autopsy findings in patients who had an acute stroke.

Hudák, Lilla / Nagy, Attila Csaba / Molnár, Sarolta / Méhes, Gábor / Nagy, Katalin Erzsébet / Oláh, László / Csiba, László

Stroke and vascular neurology

2022 Volume 7, Issue 3, Page(s) 215–221

Abstract: Objectives: According to international observations, the incidence of clinical autopsies is declining worldwide, plummeting below 5% in the USA and many European countries. It is an unfavourable trend as, in 7%-12% of cases, recent clinicopathological ... ...

Abstract	Objectives: According to international observations, the incidence of clinical autopsies is declining worldwide, plummeting below 5% in the USA and many European countries. It is an unfavourable trend as, in 7%-12% of cases, recent clinicopathological studies found discrepancies that might have changed the therapy or the outcome if known premortem. As previous large-scale observations have examined varied patient populations, we aimed to focus on the differences between the clinical and pathological diagnostic findings in only patients who had a stroke. Material and methods: We assessed the postmortem non-neuropathological and neuropathological findings of 534 consecutive patients who had a stroke who passed away. Systemic neoplasms, pneumonias, thromboembolisms and haemorrhagic transformations revealed only by autopsy were considered severe abnormalities; in addition, benign abnormalities important from an educational or scientific point of view were also recorded. Results: In 26 of the 534 cases (4.9%), the presence of systemic neoplasms had already been confirmed in the clinical stage; however, 8 (1.5%) malignant tumours were only detected during autopsy. Also, 80 (15%) thromboembolic events, 73 (13.6%) pneumonias and 66 (18%) haemorrhagic transformations were only diagnosed at autopsy. Longer hospital stay (from admission to death) resulted in fewer discrepancies between clinical and autopsy diagnosis of thromboembolic events and pneumonias (p<0.01). In 169 cases, benign findings were detected. Conclusions: While the type of acute stroke is reliably diagnosed with imaging techniques, postmortem autopsies are also important in patients who had a stroke as autopsies may reveal clinically silent diseases (eg, tumour), and contribute to knowing the actual incidence of stroke-related thromboembolic and pneumonia complications.
MeSH term(s)	Autopsy ; Cause of Death ; Diagnostic Errors ; Humans ; Neoplasms ; Pneumonia ; Retrospective Studies ; Stroke/diagnosis ; Stroke/epidemiology ; Thromboembolism
Language	English
Publishing date	2022-01-31
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2059-8696
ISSN (online)	2059-8696
DOI	10.1136/svn-2021-001030
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Article ; Online: Case report: Complex evaluation of coagulation, fibrinolysis and inflammatory cytokines in a SARS-CoV-2 infected pregnant woman with fetal loss.

Tóth, Eszter Lilla / Orbán-Kálmándi, Rita / Bagoly, Zsuzsa / Lóczi, Linda / Deli, Tamás / Török, Olga / Molnár, Sarolta / Baráth, Sándor / Singh, Parvind / Hevessy, Zsuzsanna / Katona, Éva / Fagyas, Miklós / Szabó, Attila Ádám / Molnár, Szabolcs / Krasznai, Zoárd Tibor

Frontiers in immunology

2024 Volume 15, Page(s) 1329236

Abstract: Background: SARS-CoV-2 infection during pregnancy increases the risk of severe obstetrical complications. Detailed evaluation of COVID-19-associated coagulopathy in a pregnancy with stillbirth hasn't been described so far. Besides knowledge gaps in the ... ...

Abstract	Background: SARS-CoV-2 infection during pregnancy increases the risk of severe obstetrical complications. Detailed evaluation of COVID-19-associated coagulopathy in a pregnancy with stillbirth hasn't been described so far. Besides knowledge gaps in the pathomechanism leading to stillbirth in COVID-19 pregnancies, currently, no prognostic biomarker is available to identify pregnant patients who are at imminent risk of COVID-19-associated maternal and fetal complications, requiring immediate medical attention. Case: Here we report the case of a 28-year-old SARS-CoV-2 infected pregnant patient, admitted to our hospital at 28 weeks of gestation with intrauterine fetal loss. The presence of SARS-CoV-2 placentitis was confirmed by immunohistological evaluation of the placenta. She had only mild upper respiratory symptoms and her vital signs were within reference throughout labor and postpartum. The stillborn infant was delivered per vias naturales. Fibrinogen concentrate was administered before and after labor due to markedly decreased fibrinogen levels (1.49 g/l) at admission and excessive bleeding during and after delivery. Although coagulation screening tests were not alarming at admission, the balance of hemostasis was strikingly distorted in the patient. As compared to healthy age- and gestational age-matched pregnant controls, increased D-dimer, low FVIII activity, low FXIII level, marked hypocoagulability as demonstrated by the thrombin generation assay, together with shortened clot lysis and decreased levels of fibrinolytic proteins were observed. These alterations most likely have contributed to the increased bleeding observed during labor and in the early postpartum period. Interestingly, at the same time, only moderately altered inflammatory cytokine levels were found at admission. Serum ACE2 activity did not differ in the patient from that of age- and gestational age-matched healthy controls, suggesting that despite previous speculations in the literature, ACE2 may not be used as a potential biomarker for the prediction of COVID-19 placentitis and threatening fetal loss in SARS-CoV-2-infected pregnancies. Conclusions: Although based on this case report no prognostic biomarker could be identified for use in pregnant patients with imminent risk of fetal loss associated with COVID-19 placentitis, the above-described hemostasis alterations warrant awareness of postpartum hemorrhagic complications and could be helpful to identify patients requiring intensified medical attention.
MeSH term(s)	Humans ; Female ; Infant ; Pregnancy ; Adult ; Fibrinolysis ; SARS-CoV-2 ; Cytokines ; Angiotensin-Converting Enzyme 2 ; Pregnant Women ; Stillbirth ; COVID-19/complications ; Chorioamnionitis ; Biomarkers ; Fibrinogen
Chemical Substances	Cytokines ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) ; Biomarkers ; Fibrinogen (9001-32-5)
Language	English
Publishing date	2024-02-21
Publishing country	Switzerland
Document type	Case Reports ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2024.1329236
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Article ; Online: Thyroid Carcinoma Coexisting with Hashimoto's Thyreoiditis: Clinicopathological and Molecular Characteristics Clue up Pathogenesis.

Molnár, Csaba / Molnár, Sarolta / Bedekovics, Judit / Mokánszki, Attila / Győry, Ferenc / Nagy, Endre / Méhes, Gábor

Pathology oncology research : POR

2019 Volume 25, Issue 3, Page(s) 1191–1197

Abstract: Thyroid cancer (TC) coexisting with Hashimoto's thyroiditis (HT) presents with several characteristic features including multifocality and lower clinical stages compared to de novo carcinomas but its exact biology is still not understood. We reexamined ... ...

Abstract	Thyroid cancer (TC) coexisting with Hashimoto's thyroiditis (HT) presents with several characteristic features including multifocality and lower clinical stages compared to de novo carcinomas but its exact biology is still not understood. We reexamined clinico-pathological and molecular correlations between Hashimoto's thyroditis and papillary thyroid cancer. A total of 262 patients with TC was evaluated who underwent thyroidectomy at the Surgical Department of the University of Debrecen. Clinical data, histology and molecular data were evaluated. Our cohort included 43 patients (16.4%) with (5 male, 38 female) and 219 (83.6%) patients without coexisting HT (48 male, 171 female). Hashimoto's thyroiditis related thyroid cancer presented predominantly (93.0% of the cases) with the papillary histological type. Multifocality was observed more frequently with coexisting HT (16/40; 40.0%) compared to cases uninvolved (45/190; 23.7%)(p = 0.034). In contrast, lymphatic metastasis (pN1) with a significantly reduced frequency in patients with HT (4/11; 36.4%) then without HT (34/41 pN1; 82.9%)(p = 0.002). BRAF V600E mutation could be demonstrated at significantly lower rates in cases of PTC + HT (32.1 vs 60.7%, p < 0.005). High incidence, multifocality and papillary morphology strongly support a causal relation between TC and preexisting Hashimoto's thyroiditis, the latter to be considered as a preneoplastic condition promoting thyroid carcinogenesis.
MeSH term(s)	Adult ; Female ; Follow-Up Studies ; Hashimoto Disease/complications ; Hashimoto Disease/pathology ; Hashimoto Disease/surgery ; Humans ; Male ; Middle Aged ; Precancerous Conditions/complications ; Precancerous Conditions/pathology ; Precancerous Conditions/surgery ; Prognosis ; Thyroid Cancer, Papillary/complications ; Thyroid Cancer, Papillary/pathology ; Thyroid Cancer, Papillary/surgery ; Thyroid Neoplasms/complications ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/surgery ; Thyroidectomy
Language	English
Publishing date	2019-01-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1375979-6
ISSN	1532-2807 ; 1219-4956
ISSN (online)	1532-2807
ISSN	1219-4956
DOI	10.1007/s12253-019-00580-w
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Article: A Hashimoto-thyreoiditisben kialakuló papillaris pajzsmirigy-carcinoma klinikopatológiai jellegzetességei.

Molnár, Sarolta / Győry, Ferenc / Nagy, Endre / Méhes, Gábor / Molnár, Csaba

Orvosi hetilap

2017 Volume 158, Issue 5, Page(s) 178–182

Abstract: Introduction and aim: Former studies suggest the frequent coexistence of Hashimoto's thyreoditis with papillary thyroid cancer, frequently featured by multifocal carcinogenesis but lower clinical stages compared to thyroid cancers lacking thyroiditis. ... ...

Title translation	Clinico-pathological features of papillary thyroid cancer coexistent with Hashimoto's thyroiditis.
Abstract	Introduction and aim: Former studies suggest the frequent coexistence of Hashimoto's thyreoditis with papillary thyroid cancer, frequently featured by multifocal carcinogenesis but lower clinical stages compared to thyroid cancers lacking thyroiditis. We examined the clinico-pathological correlations between Hashimoto's thyroditis and papillary thyroid cancer in our region in the North-Eastern part of Hungary. Patients and method: We included a total of 230 patients with papillary thyroid cancer who underwent thyroid surgery at the Surgical Department of the University of Debrecen. Patients' sex, age, multifocality of thyroid cancer and clinical stage were evaluated. Results: Cases included 40 patients (17.4%) with (4 male, 36 female) and 190 (82.6%) patients without HT (44 male, 146 female). Hashimoto's thyroiditis related thyroid cancer was almost exclusively associated with the papillary histological type. Multifocality of papillary cancer was significantly more frequent with coexisting Hashimoto's thyroiditis (16/40; 40.0%) compared to cases uninvolved (45/190; 23.7%; p = 0.034). In contrast, lymph node metastasis was significantly less frequent among patients with Hashimoto's thyroiditis (4 pN1 [36.4%]; 7 pN0 [63.6%]) then without it (34 pN1 [82.9%]; 7 pN0 [17.1%]; p = 0.002). Conclusion: Higher frequency and multifocality of papillary thyroid cancer might be the consequence of preexisting Hashimoto's thyroiditis to be considered as a preneoplastic stimulus supporting carcinogenesis, though the exact pathomechanism of this correlation is not clear yet. Orv. Hetil., 2017, 158(5), 178-182.
MeSH term(s)	Adult ; Carcinoma, Papillary/complications ; Carcinoma, Papillary/pathology ; Carcinoma, Papillary/surgery ; Female ; Hashimoto Disease/complications ; Hashimoto Disease/pathology ; Hashimoto Disease/surgery ; Humans ; Hungary ; Male ; Middle Aged ; Retrospective Studies ; Thyroid Neoplasms/complications ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/surgery ; Thyroidectomy
Language	Hungarian
Publishing date	2017-02
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2017.30647
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