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  1. Article ; Online: Application of magnetic resonance spectroscopy in geriatric mood disorders.

    Mathias, Liana K / Monette, Patrick J / Harper, David G / Forester, Brent P

    International review of psychiatry (Abingdon, England)

    2017  Volume 29, Issue 6, Page(s) 597–617

    Abstract: The prevalence of mood disorders in the rapidly-growing older adult population merits attention due to the likelihood of increased medical comorbidities, risk of hospitalization or institutionalization, and strains placed on caregivers and healthcare ... ...

    Abstract The prevalence of mood disorders in the rapidly-growing older adult population merits attention due to the likelihood of increased medical comorbidities, risk of hospitalization or institutionalization, and strains placed on caregivers and healthcare providers. Magnetic resonance spectroscopy (MRS) quantifies biochemical compounds in vivo, and has been used specifically for analyses of neural metabolism and bioenergetics in older adults with mood disorders, usually via proton or phosphorous spectroscopy. While yet to be clinically implemented, data gathered from research subjects may help indicate potential biomarkers of disease state or trait or putative drug targets. Three prevailing hypotheses for these mood disorders are used as a framework for the present review, and the current biochemical findings within each are discussed with respect to particular metabolites and brain regions. This review covers studies of MRS in geriatric mood disorders and reveals persisting gaps in research knowledge, especially with regard to older age bipolar disorder. Further MRS work, using higher field strengths and larger sample sizes, is warranted in order to better understand the neurobiology of these prevalent late-life disorders.
    MeSH term(s) Aging ; Bipolar Disorder/diagnostic imaging ; Bipolar Disorder/metabolism ; Bipolar Disorder/pathology ; Brain/metabolism ; Brain/pathology ; Humans ; Magnetic Resonance Spectroscopy ; Mood Disorders/diagnostic imaging ; Mood Disorders/metabolism ; Mood Disorders/pathology
    Language English
    Publishing date 2017
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1018090-4
    ISSN 1369-1627 ; 0954-0261
    ISSN (online) 1369-1627
    ISSN 0954-0261
    DOI 10.1080/09540261.2017.1397608
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Incorporating Information From Electronic and Social Media Into Psychiatric and Psychotherapeutic Patient Care: Survey Among Clinicians.

    Hobbs, Katherine W / Monette, Patrick J / Owoyemi, Praise / Beard, Courtney / Rauch, Scott L / Ressler, Kerry J / Vahia, Ipsit V

    Journal of medical Internet research

    2019  Volume 21, Issue 7, Page(s) e13218

    Abstract: Background: Obtaining collateral information from a patient is an essential component of providing effective psychiatric and psychotherapeutic care. Research indicates that patients' social and electronic media contains information relevant to their ... ...

    Abstract Background: Obtaining collateral information from a patient is an essential component of providing effective psychiatric and psychotherapeutic care. Research indicates that patients' social and electronic media contains information relevant to their psychotherapy and clinical care. However, it remains unclear to what degree this content is being actively utilized by clinicians as a part of diagnosis or therapy. Moreover, clinicians' attitudes around this practice have not been well characterized.
    Objective: This survey aimed to establish the current attitudes and behaviors of outpatient clinicians regarding the incorporation of patients' social and electronic media into psychotherapy.
    Methods: A Web-based survey was sent to outpatient psychotherapists associated with McLean Hospital in Belmont, Massachusetts. The survey asked clinicians to indicate to what extent and with which patients they reviewed patients' social and electronic media content as part of their clinical practice, as well as their reasons for or against doing so.
    Results: Of the total 115 respondents, 71 (61.7%) indicated that they had viewed at least one patient's social or electronic media as part of psychotherapy, and 65 of those 71 (92%) endorsed being able to provide more effective treatment as a result of this information. The use of either short message service text messages or email was significantly greater than the use of other electronic media platforms (χ
    Conclusions: The incorporation of patients' social and electronic media into therapy is currently common practice among clinicians at a large psychiatric teaching hospital. The results of this survey have informed further questions about whether reviewing patient's media impacts the quality and efficacy of clinical care.
    MeSH term(s) Female ; Humans ; Male ; Psychiatry/methods ; Psychotherapy/methods ; Social Media/standards ; Surveys and Questionnaires ; Telemedicine/methods ; Treatment Outcome
    Language English
    Publishing date 2019-07-12
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1439-4456
    ISSN (online) 1438-8871
    ISSN 1439-4456
    DOI 10.2196/13218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Returning Individual Research Results from Digital Phenotyping in Psychiatry.

    Shen, Francis X / Baum, Matthew L / Martinez-Martin, Nicole / Miner, Adam S / Abraham, Melissa / Brownstein, Catherine A / Cortez, Nathan / Evans, Barbara J / Germine, Laura T / Glahn, David C / Grady, Christine / Holm, Ingrid A / Hurley, Elisa A / Kimble, Sara / Lázaro-Muñoz, Gabriel / Leary, Kimberlyn / Marks, Mason / Monette, Patrick J / Onnela, Jukka-Pekka /
    O'Rourke, P Pearl / Rauch, Scott L / Shachar, Carmel / Sen, Srijan / Vahia, Ipsit / Vassy, Jason L / Baker, Justin T / Bierer, Barbara E / Silverman, Benjamin C

    The American journal of bioethics : AJOB

    2023  Volume 24, Issue 2, Page(s) 69–90

    Abstract: Psychiatry is rapidly adopting digital phenotyping and artificial intelligence/machine learning tools to study mental illness based on tracking participants' locations, online activity, phone and text message usage, heart rate, sleep, physical activity, ... ...

    Abstract Psychiatry is rapidly adopting digital phenotyping and artificial intelligence/machine learning tools to study mental illness based on tracking participants' locations, online activity, phone and text message usage, heart rate, sleep, physical activity, and more. Existing ethical frameworks for return of individual research results (IRRs) are inadequate to guide researchers for when, if, and how to return this unprecedented number of potentially sensitive results about each participant's real-world behavior. To address this gap, we convened an interdisciplinary expert working group, supported by a National Institute of Mental Health grant. Building on established guidelines and the emerging norm of returning results in participant-centered research, we present a novel framework specific to the ethical, legal, and social implications of returning IRRs in digital phenotyping research. Our framework offers researchers, clinicians, and Institutional Review Boards (IRBs) urgently needed guidance, and the principles developed here in the context of psychiatry will be readily adaptable to other therapeutic areas.
    MeSH term(s) Humans ; Artificial Intelligence ; Psychiatry ; Mental Disorders/therapy ; Ethics Committees, Research ; Research Personnel
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2023.2180109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6814: Show issues Location:
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