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  1. Article: Prevalence of Infective Endocarditis among Patients with

    Papadimitriou-Olivgeris, Matthaios / Guery, Benoit / Monney, Pierre / Senn, Laurence / Steinmetz, Sylvain / Boillat-Blanco, Noémie

    Microorganisms

    2024  Volume 12, Issue 2

    Abstract: We aimed to evaluate the occurrence of infective endocarditis (IE) among patients with bone and joint infections (BJIs) ... ...

    Abstract We aimed to evaluate the occurrence of infective endocarditis (IE) among patients with bone and joint infections (BJIs) and
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12020342
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Résonance magnétique cardiovasculaire en pratique clinique : pour qui, quand et pourquoi ?

    Antiochos, Panagiotis / Masi, Ambra / Maurizi, Niccolo / Monney, Pierre / Schwitter, Jürg

    Revue medicale suisse

    2023  Volume 19, Issue 828, Page(s) 1015–1022

    Abstract: Cardiovascular magnetic resonance (CMR) is an imaging modality with growing indications in cardiology. The purpose of this article is to illustrate the current clinical applications of CMR across the spectrum of ischemic heart disease, non-ischemic ... ...

    Title translation Cardiovascular magnetic resonance in clinical practice: who, when and why?
    Abstract Cardiovascular magnetic resonance (CMR) is an imaging modality with growing indications in cardiology. The purpose of this article is to illustrate the current clinical applications of CMR across the spectrum of ischemic heart disease, non-ischemic cardiomyopathies, cardiac arrhythmias and valvular or vascular heart disease. The strengths of CMR lie in its ability to comprehensively image, without the need for ionizing radiation, cardiac and vascular anatomy, function, perfusion, viability and physiology, providing a powerful non-invasive tool for patient diagnosis and prognostication.
    MeSH term(s) Humans ; Magnetic Resonance Imaging ; Heart ; Heart Diseases ; Myocardial Ischemia/diagnostic imaging ; Vascular Diseases ; Magnetic Resonance Spectroscopy
    Language French
    Publishing date 2023-05-23
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2023.19.828.1015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
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  3. Article: Mitral Valve Prolapse, Arrhythmias, and Sudden Cardiac Death: The Role of Multimodality Imaging to Detect High-Risk Features.

    Pavon, Anna Giulia / Monney, Pierre / Schwitter, Juerg

    Diagnostics (Basel, Switzerland)

    2021  Volume 11, Issue 4

    Abstract: Mitral valve prolapse (MVP) was first described in the 1960s, and it is usually a benign condition. However, a subtype of patients are known to have a higher incidence of ventricular arrhythmias and sudden cardiac death, the so called "arrhythmic MVP." ... ...

    Abstract Mitral valve prolapse (MVP) was first described in the 1960s, and it is usually a benign condition. However, a subtype of patients are known to have a higher incidence of ventricular arrhythmias and sudden cardiac death, the so called "arrhythmic MVP." In recent years, several studies have been published to identify the most important clinical features to distinguish the benign form from the potentially lethal one in order to personalize patient's treatment and follow-up. In this review, we specifically focused on
    Language English
    Publishing date 2021-04-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics11040683
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  4. Article: Prolapsus mitral : une étiologie méconnue d’arythmie ventriculaire et de mort subite.

    Graf, Guillaume / Pascale, Patrizio / Monney, Pierre

    Revue medicale suisse

    2021  Volume 17, Issue 740, Page(s) 1029–1033

    Abstract: Mitral prolapse is a common condition, defined by the systolic bulging of at least one mitral leaflet into the left atrium, which is often accompanied by various degree of mitral insufficiency. While for most of the patients the prognosis is linked to ... ...

    Title translation Mitral valve prolapse: beyond mitral regurgitation, the arrhythmic risk.
    Abstract Mitral prolapse is a common condition, defined by the systolic bulging of at least one mitral leaflet into the left atrium, which is often accompanied by various degree of mitral insufficiency. While for most of the patients the prognosis is linked to the severity of the valve regurgitation and its repercussions on the left ventricle (dilation and/or dysfunction), a minority of patients present with severe ventricular arrhythmia and an increased risk of sudden cardiac death, irrespective of the severity of the mitral regurgitation. To describe this particular condition, the terms arrhythmic or malignant mitral valve prolapse have been coined. The aim of this article is to describe the clinical, electrocardiographic and morphologic characteristics, which have been associated with an increased risk of arrhythmia in patients with mitral prolapse.
    MeSH term(s) Arrhythmias, Cardiac/epidemiology ; Arrhythmias, Cardiac/etiology ; Death, Sudden, Cardiac ; Heart Valve Diseases ; Humans ; Mitral Valve Insufficiency/epidemiology ; Mitral Valve Insufficiency/etiology ; Mitral Valve Prolapse/complications ; Mitral Valve Prolapse/epidemiology
    Language French
    Publishing date 2021-05-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Molécules chaperons : exemple de la maladie de Fabry.

    Barbey, Frédéric / Monney, Pierre / Dormond, Olivier

    Nephrologie & therapeutique

    2021  Volume 17S, Page(s) S11–S22

    Abstract: Fabry disease is due to mutations in the GLA gene that cause a deficiency of the activity of the lysosomal enzyme alpha-galactosidase A (α-gal A) resulting in intra-tissue accumulation of globotriaosylceramide. Recently, a novel therapeutic approach ... ...

    Title translation Chaperone molecules: The example of Fabry disease.
    Abstract Fabry disease is due to mutations in the GLA gene that cause a deficiency of the activity of the lysosomal enzyme alpha-galactosidase A (α-gal A) resulting in intra-tissue accumulation of globotriaosylceramide. Recently, a novel therapeutic approach based on the pharmacological chaperone migalastat has been developed. It binds, in a specific and reversible manner, to the catalytic site of α-gal A mutants, to prevent their degradation by the quality control system of the endoplasmic reticulum and allow them to catabolize globotriaosylceramide in the lysosomes. This treatment concerns approximately 35% of the GLA gene mutations recognized as sensitive to migalastat according to an in vitro pharmacogenetic test. Two pivotal Phase III studies, FACETS: migalastat vs. placebo and ATTRACT: migalastat vs. enzyme replacement therapy analyzed the in vivo effects of migalastat. Despite some methodological limitations, promising results were found. Migalastat seems to be more effective than enzyme replacement therapy in reducing left ventricular mass index in case of cardiac hypertrophy and has comparable renal effects. This oral treatment is the first personalized treatment, based on the genetic profile of Fabry patients and opens a new era in the management of conformational diseases.
    MeSH term(s) Enzyme Replacement Therapy ; Fabry Disease/drug therapy ; Fabry Disease/genetics ; Humans ; Kidney ; Mutation ; alpha-Galactosidase/genetics
    Chemical Substances alpha-Galactosidase (EC 3.2.1.22)
    Language French
    Publishing date 2021-04-28
    Publishing country France
    Document type Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2020.02.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Thrombocytopenia among Patients Undergoing Aortic Valve Replacement Using the Sutureless Perceval S Bioprosthesis: A Retrospective Study.

    Jayet, Adrien / Lu, Henri / Monney, Pierre / Verdugo-Marchese, Mario / Gunga, Ziyad / Rancati, Valentina / Ltaief, Zied / Kirsch, Matthias

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: Background: The sutureless Perceval S bioprosthesis is associated with postoperative thrombocytopenia. Our objectives were to compare the incidence, severity, and clinical implications of thrombocytopenia after aortic valve replacement (AVR) using the ... ...

    Abstract Background: The sutureless Perceval S bioprosthesis is associated with postoperative thrombocytopenia. Our objectives were to compare the incidence, severity, and clinical implications of thrombocytopenia after aortic valve replacement (AVR) using the Perceval S or the Trifecta bioprosthesis.
    Methods: Patients who underwent AVR between March 2016 and August 2019 using the Perceval or Trifecta were retrospectively included. The primary endpoint was the nadir in platelet counts within 15 days after surgery. Secondary endpoints included postoperative hemolysis and inflammatory parameters, as well as clinical and echocardiographic outcomes.
    Results: Overall, 156 patients were included (Perceval,
    Conclusion: The Perceval S bioprosthesis was associated with more severe postoperative thrombocytopenia. This did not translate into higher short-term morbidity or mortality.
    Language English
    Publishing date 2024-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13041083
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  7. Article ; Online: Eyes Wide Shut: A Cohort Study Questioning the Role of Fundoscopy in Infective Endocarditis Diagnosis.

    Stavropoulou, Elisavet / Guery, Benoit / Tzimas, Georgios / Guex-Crosier, Yan / Hoogewoud, Florence / Tozzi, Piergiorgio / Kirsch, Matthias / Monney, Pierre / Papadimitriou-Olivgeris, Matthaios

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  Volume 78, Issue 3, Page(s) 663–666

    Abstract: In this retrospective/prospective study, we assessed the role of fundoscopy in 711 episodes with suspected infective endocarditis (IE); 238 (33%) had IE. Ocular embolic events (retinal emboli or chorioretinitis/endophthalmitis) and Roth spots were found ... ...

    Abstract In this retrospective/prospective study, we assessed the role of fundoscopy in 711 episodes with suspected infective endocarditis (IE); 238 (33%) had IE. Ocular embolic events (retinal emboli or chorioretinitis/endophthalmitis) and Roth spots were found in 37 (5%) and 34 (5%) episodes, respectively, but had no impact on IE diagnosis.
    MeSH term(s) Humans ; Cohort Studies ; Retrospective Studies ; Prospective Studies ; Endocarditis/diagnosis ; Endocarditis, Bacterial/diagnostic imaging ; Embolism
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciae067
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    Zs.A 1505: Show issues Location:
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    Zs.MO 480: Show issues

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  8. Article ; Online: Association of persistent positive blood cultures and infective endocarditis: A cohort study among patients with suspected infective endocarditis.

    Teixeira Antunes, André / Monney, Pierre / Tzimas, Georgios / Tozzi, Piergiorgio / Kirsch, Matthias / Guery, Benoit / Papadimitriou-Olivgeris, Matthaios

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2024  Volume 143, Page(s) 107022

    Abstract: Objectives: To ascertain whether infective endocarditis (IE) was associated with persistent bacteraemia/candidaemia among patients with suspected IE.: Methods: This study included bacteraemic/candidaemic adult patients with echocardiography and ... ...

    Abstract Objectives: To ascertain whether infective endocarditis (IE) was associated with persistent bacteraemia/candidaemia among patients with suspected IE.
    Methods: This study included bacteraemic/candidaemic adult patients with echocardiography and follow-up blood cultures. Persistent bacteraemia/candidaemia was defined as continued positive blood cultures with the same microorganism for 48 h or more after antibiotic treatment initiation. Each case was classified for IE by the Endocarditis Team.
    Results: Among 1962 episodes of suspected IE, IE (605; 31%) was the most prevalent infection type. Persistent bacteraemia/candidaemia was observed in 426 (22%) episodes. Persistent bacteraemia was more common among episodes with Staphylococcus aureus bacteraemia compared to episodes with positive blood cultures for other pathogens (32%, 298/933 vs 12%, 128/1029; P < 0.001). Multivariable analysis demonstrated that cardiac predisposing factors (aOR 1.84, 95% CI 1.31-2.60), community or non-nosocomial healthcare-associated (2.85, 2.10-3.88), bacteraemia by high-risk bacteria, such as S. aureus, streptococci, enterococci or HACEK (1.84, 1.31-2.60), two or more positive sets of index blood cultures (6.99, 4.60-10.63), persistent bacteraemia/candidaemia for 48 h from antimicrobial treatment initiation (1.43, 1.05-1.93), embolic events within 48h from antimicrobial treatment initiation (12.81, 9.43-17.41), and immunological phenomena (3.87, 1.09-1.78) were associated with infective endocarditis.
    Conclusions: IE was associated with persistent bacteraemia/candidaemia, along with other commonly associated factors.
    Language English
    Publishing date 2024-03-30
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2024.107022
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  9. Article ; Online: Evaluation of the Clinical Rule for Endocarditis in the Emergency Department Among Patients With Suspected Infective Endocarditis.

    Papadimitriou-Olivgeris, Matthaios / Monney, Pierre / Carron, Pierre-Nicolas / Tzimas, Georgios / Beysard, Nicolas / Tozzi, Piergiorgio / Kirsch, Matthias / Guery, Benoit

    Journal of the American Heart Association

    2024  Volume 13, Issue 4, Page(s) e032745

    MeSH term(s) Humans ; Endocarditis, Bacterial/diagnosis ; Endocarditis, Bacterial/therapy ; Endocarditis/diagnosis ; Endocarditis/therapy ; Emergency Service, Hospital
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Letter
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.123.032745
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  10. Article ; Online: False Negative

    Redzepi, Betim / Kamani, Christel H / Maurizi, Niccolo / Théaudin, Marie / Prior, John / Monney, Pierre

    CJC open

    2023  Volume 6, Issue 2Part A, Page(s) 118–121

    Language English
    Publishing date 2023-11-21
    Publishing country United States
    Document type Case Reports
    ISSN 2589-790X
    ISSN (online) 2589-790X
    DOI 10.1016/j.cjco.2023.11.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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