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  1. Book ; Thesis: Spatial and non-spatial coding in lateral entorhinal cortex

    Huang, Xu / Monyer, Hannah

    2022  

    Institution Universität Heidelberg
    Author's details vorgelegt von Xu Huang ; Doktormutter: Frau Prof. Dr. med Hannah Monyer
    Language English
    Size iii, 83 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2022
    Note Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT030016960
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 E 814 order for loan Magazin

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  2. Book ; Thesis: Autismus aus neurobiologischer Perspektive mit besonderem Fokus auf GABAerge Projektionsneurone

    Wojak, Birgit / Monyer, Hannah

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Birgit Wojak ; Doktormutter: Frau Prof. Dr. med. Hannah Monyer
    Language German
    Size 123 Blätter, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2022
    HBZ-ID HT030032136
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Diazepam binding inhibitor regulates neurogenesis in the embryonic telencephalon via GABA signaling

    Everlien, Isabelle / Monyer, Hannah

    2021  

    Institution Universität Heidelberg
    Author's details presented by M. Sc. Isabelle Everlien ; referees: Prof. Dr. Hannah Monyer, Dr. Julieta Alfonso
    Keywords Embryonalentwicklung ; Endhirn ; Neurogenese ; Diazepam binding inhibitor ; Aminobuttersäure ; Signaltransduktion
    Subject Signalübertragung ; Signalvermittlung ; GABA ; Gamma-Aminobuttersäure ; DBI ; Acyl-CoA-Bindungsprotein ; Diazepam-Bindungsinhibitor ; EpDBI ; Endozepine ; Acyl-CoA-Binding Protein ; DBI Peptide ; Nervensystem ; Telencephalon ; Embryo ; Embryogenese ; Keimesentwicklung
    Language English
    Size 79 Seiten, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruperto Carola University Heidelberg, 2021
    Note Text Englisch, Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT021375532
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 E 640 order for loan Magazin

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  4. Book ; Thesis: Reelin and the development of the medial entorhinal cortex

    Kappos, Sofia Lavinia / Monyer, Hannah

    2020  

    Institution Universität Heidelberg
    Author's details vorgelegt von Sofia Lavinia Kappos ; Doktorvater: Prof. Dr. med. Hannah Monyer
    Language English
    Size VII, 107 Blätter, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    HBZ-ID HT021210689
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2022 E 72 order for loan Magazin

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  5. Article ; Online: Diversity and function of corticopetal and corticofugal GABAergic projection neurons.

    Melzer, Sarah / Monyer, Hannah

    Nature reviews. Neuroscience

    2020  Volume 21, Issue 9, Page(s) 499–515

    Abstract: It is still widely thought that cortical projections to distant brain areas derive by and large from glutamatergic neurons. However, an increasing number of reports provide evidence that cortical GABAergic neurons comprise a smaller population of ' ... ...

    Abstract It is still widely thought that cortical projections to distant brain areas derive by and large from glutamatergic neurons. However, an increasing number of reports provide evidence that cortical GABAergic neurons comprise a smaller population of 'projection neurons' in addition to the well-known and much-studied interneurons. GABAergic long-range axons that derive from, or project to, cortical areas are thought to entrain distant brain areas for efficient information transfer and processing. Research conducted over the past 10 years has revealed that cortical GABAergic projection neurons are highly diverse in terms of molecular marker expression, synaptic targeting (identity of targeted cell types), activity pattern during distinct behavioural states and precise temporal recruitment relative to ongoing neuronal network oscillations. As GABAergic projection neurons connect many cortical areas unidirectionally or bidirectionally, it is safe to assume that they participate in the modulation of a whole series of behavioural and cognitive functions. We expect future research to examine how long-range GABAergic projections fine-tune activity in distinct distant networks and how their recruitment alters the behaviours that are supported by these networks.
    MeSH term(s) Animals ; Behavior, Animal/physiology ; Brain/physiology ; Cerebral Cortex/physiology ; GABAergic Neurons/physiology ; Neural Pathways/physiology
    Language English
    Publishing date 2020-08-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2034150-7
    ISSN 1471-0048 ; 1471-0048 ; 1471-003X
    ISSN (online) 1471-0048
    ISSN 1471-0048 ; 1471-003X
    DOI 10.1038/s41583-020-0344-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 47: Show issues

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  6. Book ; Online ; Thesis: Hippocampal representations of homing based on path integration

    Najafian Jazi, Maryam [Verfasser] / Monyer, Hannah [Akademischer Betreuer]

    2023  

    Author's details Maryam Najafian Jazi ; Betreuer: Hannah Monyer
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Universitätsbibliothek Heidelberg
    Publishing place Heidelberg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Book ; Online ; Thesis: Space, time and item coding in the lateral entorhinal cortex and the hippocampus

    Barriuso-Ortega, Isabel [Verfasser] / Monyer, Hannah [Akademischer Betreuer]

    2023  

    Author's details Isabel Barriuso Ortega ; Betreuer: Hannah Monyer
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Universitätsbibliothek Heidelberg
    Publishing place Heidelberg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Article: Insulin-like growth factor 2 (IGF-2) rescues social deficits in NLG3

    Pizzarelli, Rocco / Pimpinella, Domenico / Jacobs, Christian / Tartacca, Alice / Kullolli, Uarda / Monyer, Hannah / Alberini, Cristina M / Griguoli, Marilena

    Frontiers in cellular neuroscience

    2024  Volume 17, Page(s) 1332179

    Abstract: Autism spectrum disorders (ASDs) comprise developmental disabilities characterized by impairments of social interaction and repetitive behavior, often associated with cognitive deficits. There is no current treatment that can ameliorate most of the ASDs ... ...

    Abstract Autism spectrum disorders (ASDs) comprise developmental disabilities characterized by impairments of social interaction and repetitive behavior, often associated with cognitive deficits. There is no current treatment that can ameliorate most of the ASDs symptomatology; thus, identifying novel therapies is urgently needed. Here, we used the Neuroligin 3 knockout mouse (NLG3
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2452963-1
    ISSN 1662-5102
    ISSN 1662-5102
    DOI 10.3389/fncel.2023.1332179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Spatial transcriptomics map of the embryonic mouse brain - a tool to explore neurogenesis.

    Di Marco, Barbara / Vázquez-Marín, Javier / Monyer, Hannah / Centanin, Lázaro / Alfonso, Julieta

    Biology open

    2023  Volume 12, Issue 10

    Abstract: The developing brain has a well-organized anatomical structure comprising different types of neural and non-neural cells. Stem cells, progenitors and newborn neurons tightly interact with their neighbouring cells and tissue microenvironment, and this ... ...

    Abstract The developing brain has a well-organized anatomical structure comprising different types of neural and non-neural cells. Stem cells, progenitors and newborn neurons tightly interact with their neighbouring cells and tissue microenvironment, and this intricate interplay ultimately shapes the output of neurogenesis. Given the relevance of spatial cues during brain development, we acknowledge the necessity for a spatial transcriptomics map accessible to the neurodevelopmental community. To fulfil this need, we generated spatially resolved RNA sequencing (RNAseq) data from embryonic day 13.5 mouse brain sections immunostained for mitotic active neural and vascular cells. Unsupervised clustering defined specific cell type populations of diverse lineages and differentiation states. Differential expression analysis revealed unique transcriptional signatures across specific brain areas, uncovering novel features inherent to particular anatomical domains. Finally, we integrated existing single-cell RNAseq datasets into our spatial transcriptomics map, adding tissue context to single-cell RNAseq data. In summary, we provide a valuable tool that enables the exploration and discovery of unforeseen molecular players involved in neurogenesis, particularly in the crosstalk between different cell types.
    MeSH term(s) Animals ; Mice ; Transcriptome ; Neurogenesis/genetics ; Cell Differentiation/genetics ; Neurons/metabolism ; Brain/metabolism
    Language English
    Publishing date 2023-10-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2632264-X
    ISSN 2046-6390 ; 2046-6390
    ISSN (online) 2046-6390
    ISSN 2046-6390
    DOI 10.1242/bio.060151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Neurogenesis in the adult brain functionally contributes to the maintenance of chronic neuropathic pain.

    Tan, Linette Liqi / Alfonso, Julieta / Monyer, Hannah / Kuner, Rohini

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 18549

    Abstract: Maladaptive adult neurogenesis in the mammalian brain has been associated with diverse behaviors including disrupted learning, negative mood disorders and psychiatric conditions. However, its functional role in the generation and maintenance of chronic ... ...

    Abstract Maladaptive adult neurogenesis in the mammalian brain has been associated with diverse behaviors including disrupted learning, negative mood disorders and psychiatric conditions. However, its functional role in the generation and maintenance of chronic pathological pain has not yet been elucidated. Using an inducible genetic deletion in vivo mouse model, different behavioural paradigms and home cage monitoring systems, we show that an absence of adult neurogenesis does not impact the development of neuropathic injury-induced peripheral nociceptive hypersensitivity, but rather promotes the recovery of pathological pain as well as improves parameters associated with the state of well-being of the injured mice. These results provide a mechanistic insight into the mechanisms of chronic pain and implicate neurogenic processes as a potential therapeutic target for reducing pain and improving the quality of life for patients.
    MeSH term(s) Adult ; Animals ; Brain/physiopathology ; Chronic Pain/physiopathology ; Humans ; Male ; Mice ; Neuralgia/physiopathology ; Neurogenesis
    Language English
    Publishing date 2021-09-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-97093-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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