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  1. Book: Textbook of critical care

    Vincent, Jean-Louis / Moore, Frederick A. / Bellomo, Rinaldo / Marini, John J.

    2024  

    Title variant Critical care
    Author's details Jean-Louis Vincent, Edward Abraham, Patrick Kochanek, Frederick A. Moore, Mitchell P. Fink
    Keywords Critical Care ; Intensive Care Units ; Critical care medicine
    Subject code 616.028
    Language English
    Size xxviii, 1423 Seiten, Illustrationen, 29 cm
    Edition 8th edition
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book
    Accompanying material Zugang zu Enhanced Digital Version über Code
    HBZ-ID HT021433254
    ISBN 978-0-323-75929-8 ; 9780323759304 ; 0-323-75929-7 ; 0323759300
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Textbook of critical care

    Vincent, Jean-Louis / Abraham, Edward / Moore, Frederick A. / Kochanek, Patrick M. / Fink, Mitchell P.

    (Expert consult)

    2017  

    Author's details Jean-Louis Vincent, MD, PhD; Edward Abraham, MD; Frederick A. Moore, MD, MCCM; Patrick M. Kochanek, MD, MCCM; Mitchell P. Fink, MD
    Series title Expert consult
    Keywords Critical Care ; Intensive Care Units
    Language English
    Size xlii, 1362 Seiten, Illustrationen, Diagramme
    Edition 7th edition
    Publisher Elsevier
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book
    Note Zugang zur Internetausgabe über Code
    HBZ-ID HT019196075
    ISBN 978-0-323-37638-9 ; 0-323-37638-X
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Chronic Critical Illness and PICS Nutritional Strategies.

    Rosenthal, Martin D / Vanzant, Erin L / Moore, Frederick A

    Journal of clinical medicine

    2021  Volume 10, Issue 11

    Abstract: The nutritional hallmark of chronic critical illness (CCI) after sepsis is persistent inflammation, immunosuppression, and catabolism syndrome (PICS), which results in global resistance to the anabolic effect of nutritional supplements. This ultimately ... ...

    Abstract The nutritional hallmark of chronic critical illness (CCI) after sepsis is persistent inflammation, immunosuppression, and catabolism syndrome (PICS), which results in global resistance to the anabolic effect of nutritional supplements. This ultimately leaves these patients in a downward phenotypic spiral characterized by cachexia with profound weakness, decreased capacity for rehabilitation, and immunosuppression with the propensity for sepsis recidivism. The persistent catabolism is driven by a pathologic low-grade inflammation with the inability to return to homeostasis and by ongoing increased energy expenditure. Better critical care support systems and advances in technology have led to increased intensive care unit (ICU) survival, but CCI due to PICS with poor long-term outcomes has emerged as a frequent phenotype among ICU sepsis survivors. Unfortunately, therapies to mitigate or reverse PICS-CCI are limited, and recent evidence supports that these patients fail to respond to early ICU evidence-based nutrition protocols. A lack of randomized controlled trials has limited strong recommendations for nutrition adjuncts in these patients. However, based on experience in other conditions characterized by a similar phenotype, immunonutrients aimed at counteracting inflammation, immunosuppression, and catabolism may be important for improving outcomes in PICS-CCI patients. This manuscript intends to review several immunonutrients as adjunctive therapies in treating PICS-CCI.
    Language English
    Publishing date 2021-05-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10112294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The evolving role of laparoscopic lavage and drainage.

    Biffl, Walter L / Moore, Frederick A / Moore, Ernest E

    The journal of trauma and acute care surgery

    2019  Volume 86, Issue 2, Page(s) 376

    MeSH term(s) Diverticulitis ; Drainage ; Humans ; Laparoscopy ; Therapeutic Irrigation
    Language English
    Publishing date 2019-01-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2651070-4
    ISSN 2163-0763 ; 2163-0755
    ISSN (online) 2163-0763
    ISSN 2163-0755
    DOI 10.1097/TA.0000000000002145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Molecular characterization of the first reported

    Northill, Judith A / Simmons, Russell J / Genge, Doris / Moore, Frederick A

    Access microbiology

    2020  Volume 2, Issue 4, Page(s) acmi000099

    Abstract: A novel real-time reverse transcription polymerase chain reaction (RT-rPCR) assay was developed to ... ...

    Abstract A novel real-time reverse transcription polymerase chain reaction (RT-rPCR) assay was developed to detect
    Language English
    Publishing date 2020-02-11
    Publishing country England
    Document type Journal Article
    ISSN 2516-8290
    ISSN (online) 2516-8290
    DOI 10.1099/acmi.0.000099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The use of lactated ringer's in shock resuscitation: the good, the bad and the ugly.

    Moore, Frederick A

    The Journal of trauma

    2011  Volume 70, Issue 5 Suppl, Page(s) S15–6

    MeSH term(s) Fluid Therapy ; Humans ; Infusions, Intravenous ; Isotonic Solutions/administration & dosage ; Isotonic Solutions/therapeutic use ; Resuscitation/methods ; Shock/drug therapy ; Shock/etiology ; Treatment Outcome ; Wounds and Injuries/complications ; Wounds and Injuries/therapy
    Chemical Substances Isotonic Solutions ; Ringer's lactate (8022-63-7)
    Language English
    Publishing date 2011-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 219302-4
    ISSN 1529-8809 ; 0022-5282 ; 1079-6061
    ISSN (online) 1529-8809
    ISSN 0022-5282 ; 1079-6061
    DOI 10.1097/TA.0b013e31821a4d6e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Presidential address: imagination trumps knowledge.

    Moore, Frederick A

    American journal of surgery

    2010  Volume 200, Issue 6, Page(s) 671–677

    Abstract: Multiple organ failure (MOF) emerged 30 years ago and became our research focus. Over the years, we have proposed a series of cartoons that rallied multidisciplinary translational research teams around common themes to generate "win-win" hypotheses that ... ...

    Abstract Multiple organ failure (MOF) emerged 30 years ago and became our research focus. Over the years, we have proposed a series of cartoons that rallied multidisciplinary translational research teams around common themes to generate "win-win" hypotheses that when tested (right or wrong) have advanced our understanding of MOF. MOF has a bimodal trajectory, and the gut plays a role in both trajectories. Early MOF occurs because of excessive proinflammation (ie, systemic inflammatory response syndrome [SIRS]), and early gut ischemia-reperfusion can amplify SIRS and contribute to the early fulminant SIRS-MOF trajectory. Fortunately, most patients survive early SIRS, but some develop excessive anti-inflammation (ie, compensatory anti-inflammatory response syndrome). The gut also plays a role in this late indolent compensatory anti-inflammatory response syndrome-MOF trajectory. Multiple factors cause progressive gut dysfunction such that the gut (an important immunologic organ) worsens compensatory anti-inflammatory response syndrome and becomes the reservoir for pathogens and toxins that cause late sepsis.
    MeSH term(s) Animals ; Enteral Nutrition ; Gastrointestinal Tract/physiopathology ; Humans ; Multiple Organ Failure/etiology ; Multiple Organ Failure/physiopathology ; Multiple Organ Failure/prevention & control ; Protein-Energy Malnutrition/complications ; Protein-Energy Malnutrition/physiopathology ; Systemic Inflammatory Response Syndrome/etiology ; Systemic Inflammatory Response Syndrome/physiopathology ; Translational Medical Research
    Language English
    Publishing date 2010-12
    Publishing country United States
    Document type Addresses ; Research Support, N.I.H., Extramural
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2010.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: What's better?

    Moore, Frederick A

    JPEN. Journal of parenteral and enteral nutrition

    2010  Volume 34, Issue 6, Page(s) 600–601

    MeSH term(s) Critical Care ; Critical Illness/therapy ; Humans ; Intensive Care Units ; Nutrition Therapy/standards ; Nutritional Status ; Perioperative Care/standards ; Practice Guidelines as Topic ; Quality Improvement
    Language English
    Publishing date 2010-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 800861-9
    ISSN 0148-6071
    ISSN 0148-6071
    DOI 10.1177/0148607110376201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Autophagy: should it play a role in ICU management?

    Rosenthal, Martin D / Carrott, Phil / Moore, Frederick A

    Current opinion in critical care

    2018  Volume 24, Issue 2, Page(s) 112–117

    Abstract: Purpose of review: This review is to discuss the role of autophagy in the critically ill patient population. As the understanding of autophagy continues to expand and evolve, there are certain controversies surrounding whether intensivist should allow ... ...

    Abstract Purpose of review: This review is to discuss the role of autophagy in the critically ill patient population. As the understanding of autophagy continues to expand and evolve, there are certain controversies surrounding whether intensivist should allow the benefit of autophagy to supersede gold standard of insulin therapy or early nutritional support.
    Recent findings: The review is relevant as the current literature seems to support under-feeding patients, and perhaps the reason these studies were positive could be prescribed to the mechanisms of autophagy. It is well understood that autophagy is a physiologic response to stress and starvation, and that the inducible form could help patients with end-organ dysfunction return to homeostasis.
    Summary: The jury is still out as to how autophagy will play into clinical practice as we review several gold standard therapies for the critically ill.
    MeSH term(s) Autophagy/immunology ; Autophagy/physiology ; Critical Care/methods ; Critical Illness/therapy ; Energy Metabolism ; Humans ; Insulin/blood ; Insulin/therapeutic use ; Intensive Care Units ; Nutritional Physiological Phenomena ; Nutritional Support ; Practice Guidelines as Topic ; Stress, Physiological/physiology
    Chemical Substances Insulin
    Language English
    Publishing date 2018-02-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000000486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reviewer Acknowledgement 2012

    Catena Fausto / Moore Frederick A

    World Journal of Emergency Surgery, Vol 8, Iss 1, p

    2013  Volume 9

    Abstract: Contributing reviewers The Editors of World Journal of Emergency Surgery would like to thank all our reviewers who have contributed to the journal in Volume 7 (2012). ...

    Abstract Contributing reviewers The Editors of World Journal of Emergency Surgery would like to thank all our reviewers who have contributed to the journal in Volume 7 (2012).
    Keywords Surgery ; RD1-811 ; Medicine ; R ; DOAJ:Surgery ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2013-03-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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