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  1. Article: A new species of

    Suárez-Morales, Eduardo

    ZooKeys

    2022  Volume 1128, Page(s) 33–45

    Abstract: The taxonomic study of monstrilloid copepods is hampered by incomplete early descriptions, uncertain synonymies, and the difficulty of reliably matching males and females of species. A re-evaluation of male monstrilloid specimens collected from two reef ... ...

    Abstract The taxonomic study of monstrilloid copepods is hampered by incomplete early descriptions, uncertain synonymies, and the difficulty of reliably matching males and females of species. A re-evaluation of male monstrilloid specimens collected from two reef areas of the Mexican Caribbean allowed me to clarify the status of
    Language English
    Publishing date 2022-11-04
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2445640-8
    ISSN 1313-2970 ; 1313-2989
    ISSN (online) 1313-2970
    ISSN 1313-2989
    DOI 10.3897/zookeys.1128.84944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Mitotic spindle positioning protein (MISP) is an actin bundler that senses ADP-actin and binds near the pointed ends of filaments.

    Morales, E Angelo / Tyska, Matthew J

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Actin bundling proteins crosslink filaments into polarized structures that shape and support membrane protrusions including filopodia, microvilli, and stereocilia. In the case of epithelial microvilli, mitotic spindle positioning protein (MISP) is an ... ...

    Abstract Actin bundling proteins crosslink filaments into polarized structures that shape and support membrane protrusions including filopodia, microvilli, and stereocilia. In the case of epithelial microvilli, mitotic spindle positioning protein (MISP) is an actin bundler that localizes specifically to the basal rootlets, where the pointed ends of core bundle filaments converge. Previous studies established that MISP is prevented from binding more distal segments of the core bundle by competition with other actin binding proteins. Yet whether MISP holds a preference for binding directly to rootlet actin remains an open question. Using
    Language English
    Publishing date 2023-05-06
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.05.05.539649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Characterizing Biogenic MnOx Produced by

    Morales, Elisa / Shaner, Sarah E / Stone, Kari L

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 2

    Abstract: Mn-oxidizing microorganisms oxidize environmental Mn(II), producing Mn(IV) oxides. ...

    Abstract Mn-oxidizing microorganisms oxidize environmental Mn(II), producing Mn(IV) oxides.
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14020171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mitotic spindle positioning protein (MISP) preferentially binds to aged F-actin.

    Morales, E Angelo / Fitz, Gillian N / Tyska, Matthew J

    The Journal of biological chemistry

    2024  Volume 300, Issue 5, Page(s) 107279

    Abstract: Actin bundling proteins crosslink filaments into polarized structures that shape and support membrane protrusions including filopodia, microvilli, and stereocilia. In the case of epithelial microvilli, mitotic spindle positioning protein (MISP) is an ... ...

    Abstract Actin bundling proteins crosslink filaments into polarized structures that shape and support membrane protrusions including filopodia, microvilli, and stereocilia. In the case of epithelial microvilli, mitotic spindle positioning protein (MISP) is an actin bundler that localizes specifically to the basal rootlets, where the pointed ends of core bundle filaments converge. Previous studies established that MISP is prevented from binding more distal segments of the core bundle by competition with other actin-binding proteins. Yet whether MISP holds a preference for binding directly to rootlet actin remains an open question. By immunostaining native intestinal tissue sections, we found that microvillar rootlets are decorated with the severing protein, cofilin, suggesting high levels of ADP-actin in these structures. Using total internal reflection fluorescence microscopy assays, we also found that purified MISP exhibits a binding preference for ADP- versus ADP-Pi-actin-containing filaments. Consistent with this, assays with actively growing actin filaments revealed that MISP binds at or near their pointed ends. Moreover, although substrate attached MISP assembles filament bundles in parallel and antiparallel configurations, in solution MISP assembles parallel bundles consisting of multiple filaments exhibiting uniform polarity. These discoveries highlight nucleotide state sensing as a mechanism for sorting actin bundlers along filaments and driving their accumulation near filament ends. Such localized binding might drive parallel bundle formation and/or locally modulate bundle mechanical properties in microvilli and related protrusions.
    Language English
    Publishing date 2024-04-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2024.107279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Alloy Steel : Properties and Use

    Valencia Morales, Eduardo

    2011  

    Keywords Pharmaceutical technology ; Metals technology / metallurgy
    Size 1 electronic resource (272 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021049085
    ISBN 9789535160847 ; 9535160842
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: SGLT2 inhibitors in lupus nephropathy, a new therapeutic strategy for nephroprotection.

    Morales, Enrique / Galindo, Maria

    Annals of the rheumatic diseases

    2022  Volume 81, Issue 9, Page(s) 1337–1338

    Language English
    Publishing date 2022-08-11
    Publishing country England
    Document type Letter
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2022-222512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A new species of Monstrilla (Copepoda, Monstrilloida) from the western Caribbean with comments on M. wandelii Stephensen, 1913 and M. conjunctiva Giesbrecht, 1893

    Suárez-Morales, Eduardo

    ZooKeys. 2022 Nov. 04, v. 1128 p.33-45

    2022  

    Abstract: AbstractThe taxonomic study of monstrilloid copepods is hampered by incomplete early descriptions, uncertain synonymies, and the difficulty of reliably matching males and females of species. A re-evaluation of male monstrilloid specimens collected from ... ...

    Abstract AbstractThe taxonomic study of monstrilloid copepods is hampered by incomplete early descriptions, uncertain synonymies, and the difficulty of reliably matching males and females of species. A re-evaluation of male monstrilloid specimens collected from two reef areas of the Mexican Caribbean allowed me to clarify the status of Monstrilla mariaeugeniae Suárez-Morales & Islas-Landeros, 1993 and M. wandelii Stephensen, 1913 based on a comparison of males attributed to each of these species. Males from the Puerto Morelos reef system, northern Mexican Caribbean coast, were first proposed as a tropical subspecies of the subarctic M. wandelii

    later on, morphologically close males collected from the Mahahual reef area, southern Mexican Caribbean coast, were designated as the males of M. mariaeugeniae . Their status is here corrected with the description of M. mahahualensis sp. nov. based on the Mahahual males; the new species shares the same type of genitalia with the antarctic M. conjunctiva Giesbrecht, 1892 and the subarctic M. wandelii; Park (1967) linked a single male from Vancouver to M. wandelii. It was realised that Park’s (1967) males from the Vancouver area and the two Mexican Caribbean groups of males represent different, undescribed species. I here reassign the males earlier attributed to M. mariaeugeniae as a new species of Monstrilla which is herein described. The new species differs from the males of M. conjunctiva and M. wandelii by details of the genitalia, length of the setae of the fifth legs, armature and integumental structures of the antennules, and size of the outer exopodal spines of legs 1–4. This is the third known species of Monstrilla with a M. conjunctiva-like male genitalia and the first one known from tropical areas. The male of both M. mariaeugeniae and M. wandelii remain unknown.
    Keywords Monstrilloida ; coasts ; male genitalia ; males ; new species ; Antarctic region ; Caribbean ; Mexican Caribbean ; Monstrillidae ; morphology ; protelean endoparasites ; taxonomy
    Language English
    Dates of publication 2022-1104
    Size p. 33-45.
    Publishing place Pensoft Publishers
    Document type Article ; Online
    ZDB-ID 2445640-8
    ISSN 1313-2970 ; 1313-2989
    ISSN (online) 1313-2970
    ISSN 1313-2989
    DOI 10.3897/zookeys.1128.84944
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: A new genus of the Monstrilloida (Copepoda) with large rostral process and metasomal spines, and redescription of Monstrilla spinosa Park, 1967

    Suárez-Morales, E

    Crustaceana. , v. 92, no. 9

    2019  

    Abstract: The genus Monstrilla Dana, 1849 is one of the most diverse of the copepod order Monstrilloida and has a worldwide distribution. A new genus, Spinomonstrilla n. gen. is proposed for Monstrilla spinosa Park, 1967 from Canada and California. Spinomonstrilla ...

    Abstract The genus Monstrilla Dana, 1849 is one of the most diverse of the copepod order Monstrilloida and has a worldwide distribution. A new genus, Spinomonstrilla n. gen. is proposed for Monstrilla spinosa Park, 1967 from Canada and California. Spinomonstrilla spinosa (Park, 1970), formerly M. spinosa, the type species of the new genus, is redescribed from type specimens. The new genus shows a unique set of conspicuous characters in both males and females that clearly diverge from all other monstrilloids. It can be recognized by the presence of a large rostral process and paired dorsal metasomal spiniform processes; the female antennule structure and setation diverge from the usual monstrilloid pattern; its body shows a unique ornamentation pattern. These characters allow an easy recognition of members of Spinomonstrilla from all other Monstrilloida.
    Keywords females ; males ; Monstrilloida ; new genus ; redescriptions ; type collections ; California ; Canada
    Language English
    Size p. 1099-1112.
    Publishing place Brill
    Document type Article
    ZDB-ID 217297-5
    ISSN 0011-216X
    ISSN 0011-216X
    DOI 10.1163/15685403-00003925
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: An Experimental Method for Bio-Signal Denoising Using Unconventional Sensors.

    Aviles-Espinosa, Rodrigo / Dore, Henry / Rendon-Morales, Elizabeth

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 7

    Abstract: In bio-signal denoising, current methods reported in the literature consider purely simulated environments, requiring high computational powers and signal processing algorithms that may introduce signal distortion. To achieve an efficient noise reduction, ...

    Abstract In bio-signal denoising, current methods reported in the literature consider purely simulated environments, requiring high computational powers and signal processing algorithms that may introduce signal distortion. To achieve an efficient noise reduction, such methods require previous knowledge of the noise signals or to have certain periodicity and stability, making the noise estimation difficult to predict. In this paper, we solve these challenges through the development of an experimental method applied to bio-signal denoising using a combined approach. This is based on the implementation of unconventional electric field sensors used for creating a noise replica required to obtain the ideal Wiener filter transfer function and achieve further noise reduction. This work aims to investigate the suitability of the proposed approach for real-time noise reduction affecting bio-signal recordings. The experimental evaluation presented here considers two scenarios: (a) human bio-signals trials including electrocardiogram, electromyogram and electrooculogram; and (b) bio-signal recordings from the MIT-MIH arrhythmia database. The performance of the proposed method is evaluated using qualitative criteria (i.e., power spectral density) and quantitative criteria (i.e., signal-to-noise ratio and mean square error) followed by a comparison between the proposed methodology and state of the art denoising methods. The results indicate that the combined approach proposed in this paper can be used for noise reduction in electrocardiogram, electromyogram and electrooculogram signals, achieving noise attenuation levels of 26.4 dB, 21.2 dB and 40.8 dB, respectively.
    Language English
    Publishing date 2023-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23073527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Lupus nephropathy beyond immunosuppression: Searching for nephro and cardioprotection.

    Morales, Enrique / Sandino, Justo / Galindo, María

    Frontiers in nephrology

    2023  Volume 3, Page(s) 1105676

    Abstract: Renal involvement in systemic lupus erythematosus (SLE) represents one of the most frequent organ manifestations, often leading to end-stage kidney disease (ESKD). Several therapies have been tested in patients with lupus nephritis (LN) to prevent ... ...

    Abstract Renal involvement in systemic lupus erythematosus (SLE) represents one of the most frequent organ manifestations, often leading to end-stage kidney disease (ESKD). Several therapies have been tested in patients with lupus nephritis (LN) to prevent further organ damage. The effectiveness of immunosuppressive therapy as a treatment for LN is abundant, supported by multiple clinical trials that have shown its efficacy in preventing the development of chronic kidney disease (CKD). In addition to immunosuppressive therapy, several traditional and recent therapies aimed at nephroprotection in patients with proteinuric chronic kidney disease are gaining importance in the setting of LN. Thus, immunosuppressive therapy should be accompanied by nephro- and cardioprotective measures to control cardiovascular risk factors and proteinuria to ensure a better renal prognosis. Despite this, the literature on these specific measures is relatively scarce, with recommendations focused on the blockade of the renin-angiotensin-aldosterone system (RAAS). This review explores the pharmacological options available for cardiovascular and renal protection outside the usual treatment schemes.
    Language English
    Publishing date 2023-01-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2813-0626
    ISSN (online) 2813-0626
    DOI 10.3389/fneph.2023.1105676
    Database MEDical Literature Analysis and Retrieval System OnLINE

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