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  1. Article ; Online: The Prevalence of Bipolar Disorders and Association With Quality of Life in a Cohort of Patients With Multiple Sclerosis.

    Jun-O'Connell, Adalia H / Butala, Ankur / Morales, Idanis Berrios / Henninger, Nils / Deligiannidis, Kristina M / Byatt, Nancy / Ionete, Carolina

    The Journal of neuropsychiatry and clinical neurosciences

    2017  Volume 29, Issue 1, Page(s) 45–51

    Abstract: Clinical observations of mood instability in multiple sclerosis (MS) have led to the hypothesis that bipolar disorder (BD) may be more prevalent in persons with MS than in the general population. This cross-sectional study assesses the prevalence of BD ... ...

    Abstract Clinical observations of mood instability in multiple sclerosis (MS) have led to the hypothesis that bipolar disorder (BD) may be more prevalent in persons with MS than in the general population. This cross-sectional study assesses the prevalence of BD among patients with MS using standardized psychiatric diagnostic interviews and evaluates quality of life. This study demonstrates a higher prevalence of BD in patients with MS compared with the general population. It also reveals the negative impact of BD on quality of life, raises the concern that BD can occur before the onset of neurological symptoms in MS, and suggests that, in some cases, BD may delay diagnosis of MS.
    MeSH term(s) Adult ; Bipolar Disorder/complications ; Bipolar Disorder/epidemiology ; Bipolar Disorder/psychology ; Cohort Studies ; Comorbidity ; Cross-Sectional Studies ; Female ; Humans ; Interview, Psychological ; Male ; Middle Aged ; Multiple Sclerosis/complications ; Multiple Sclerosis/epidemiology ; Multiple Sclerosis/psychology ; Prevalence ; Quality of Life ; Self Report ; Tertiary Care Centers
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1036340-3
    ISSN 1545-7222 ; 0895-0172
    ISSN (online) 1545-7222
    ISSN 0895-0172
    DOI 10.1176/appi.neuropsych.15120403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Evaluation of a Novel Preference Assessment Tool for Patients with Multiple Sclerosis.

    Col, Nananda F / Solomon, Andrew J / Springmann, Vicky / Ionete, Carolina / Alvarez, Enrique / Tierman, Brenda / Kutz, Christen / Morales, Idanis Berrios / Griffin, Carolyn / Ngo, Long H / Jones, David E / Phillips, Glenn / Hopson, Ashli / Pbert, Lori

    International journal of MS care

    2018  Volume 20, Issue 6, Page(s) 260–267

    Abstract: Background: We developed a preference assessment tool to help assess patient goals, values, and preferences for multiple sclerosis (MS) management. All preference items in the tool were generated by people with MS. The aim of this study was to evaluate ... ...

    Abstract Background: We developed a preference assessment tool to help assess patient goals, values, and preferences for multiple sclerosis (MS) management. All preference items in the tool were generated by people with MS. The aim of this study was to evaluate this tool in a national sample of people with MS.
    Methods: English-speaking patients with MS aged 21 to 75 years with access to the internet were recruited. Participants completed the preference tool online, which included separate modules assessing three core preference areas: treatment goals, preferences for attributes of disease-modifying therapies, and factors influencing a change in treatment. The tool generated a summary of participants' treatment goals and preferences. Immediately after viewing the summary, participants were asked to evaluate the tool. Rankings of preference domains were compared with rankings obtained in another study.
    Results: In 135 people with MS who completed the tool and evaluation, the highest ranked goal was brain health (memory, thinking, brain), followed by disability concerns (walking, strength, vision). Rankings were highly similar to those in the referent study. Nearly all participants reported that the tool helped them understand their goals and priorities regarding MS and that the summary appropriately reflected what is important to them. Most participants (87%) wanted to discuss their treatment goals and priorities with their clinician.
    Conclusions: This preference assessment tool successfully captured patients' goals, values, and preferences for MS treatment and could potentially be used to help patients communicate their preferences to their clinician.
    Language English
    Publishing date 2018-12-18
    Publishing country United States
    Document type Journal Article
    ISSN 1537-2073
    ISSN 1537-2073
    DOI 10.7224/1537-2073.2017-021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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