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  1. Article ; Online: What's my hamburger meat made of?

    Morán, Paloma

    Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

    2022  Volume 51, Issue 1, Page(s) 114–119

    Abstract: Outreach activities give high school students an opportunity to better understand the techniques and strategies used by researchers. Here is an experience with high school students designed to familiarize them with genetic methodologies. Students have ... ...

    Abstract Outreach activities give high school students an opportunity to better understand the techniques and strategies used by researchers. Here is an experience with high school students designed to familiarize them with genetic methodologies. Students have been challenged to discover whether restaurant beef burgers are made with female or male beef. This represents a didactic way to introduce students to genetic traceability methodologies and also to demonstrate the usefulness of these methodologies in relation to food safety and, more importantly, in sustaining consumer confidence. The exercise is planned to be conducted in a one-day laboratory session.
    MeSH term(s) Animals ; Cattle ; Humans ; Male ; Female ; Meat ; Food Safety ; Meat Products
    Language English
    Publishing date 2022-10-21
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2039717-3
    ISSN 1539-3429 ; 1470-8175
    ISSN (online) 1539-3429
    ISSN 1470-8175
    DOI 10.1002/bmb.21685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Social Media: A Pandemic of Misinformation.

    Moran, Patrick

    The American journal of medicine

    2020  Volume 133, Issue 11, Page(s) 1247–1248

    MeSH term(s) Basic Reproduction Number ; COVID-19 ; Communication ; Humans ; Social Media
    Keywords covid19
    Language English
    Publishing date 2020-06-27
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2020.05.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Exercise to explain X-chromosome inactivation in humans.

    Morán, Paloma

    Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

    2020  Volume 48, Issue 5, Page(s) 499–501

    Abstract: Distance learning requires the combined use of techniques because it is more complicated to keep the students' attention. This exercise is designed to explain the inactivation of the x-chromosome in humans and is intended to complement the theoretical ... ...

    Abstract Distance learning requires the combined use of techniques because it is more complicated to keep the students' attention. This exercise is designed to explain the inactivation of the x-chromosome in humans and is intended to complement the theoretical explanations. It is estimated that it lasts two hours and makes use of different web resources. It is intended for students familiar with the use of BLAST tools.
    MeSH term(s) Chromosomes, Human, X ; Genetics/education ; Humans ; X Chromosome Inactivation
    Language English
    Publishing date 2020-08-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2039717-3
    ISSN 1539-3429 ; 1470-8175
    ISSN (online) 1539-3429
    ISSN 1470-8175
    DOI 10.1002/bmb.21417
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  4. Article ; Online: Is mammography screening an effective public health intervention? Evidence from a natural experiment.

    Moran, Patrick / Cullinan, John

    Social science & medicine (1982)

    2022  Volume 305, Page(s) 115073

    Abstract: Population-based breast screening programmes aim to improve clinical outcomes, alleviate health inequalities, and reduce healthcare costs. However, while screening can bring about immediate changes in mode of presentation and stage at diagnosis of breast ...

    Abstract Population-based breast screening programmes aim to improve clinical outcomes, alleviate health inequalities, and reduce healthcare costs. However, while screening can bring about immediate changes in mode of presentation and stage at diagnosis of breast cancer cases, the benefits and harms of these programmes can only be observed at a population level, and only over a long enough timeframe for the cascade of events triggered by screening to culminate in disease-specific mortality reductions. In this paper we exploit a natural experiment resulting from the phased geographic rollout of a national mammography screening programme to examine the impact of screening on breast cancer outcomes from both a patient cohort and a population perspective. Using data on 33,722 breast cancer cases over the period 1994-2011, we employ a difference-in-differences research design using ten-year follow-up data for cases diagnosed before and after the introduction of the programme in screened and unscreened regions. We conclude that although the programme produced the intended intermediate effects on breast cancer presentation and incidence, these failed to translate into significant decreases in overall population-level mortality, though screening may have helped to reduce socioeconomic disparities in late stage breast cancer incidence.
    MeSH term(s) Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/epidemiology ; Early Detection of Cancer/methods ; Female ; Humans ; Mammography ; Mass Screening ; Public Health
    Language English
    Publishing date 2022-05-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2022.115073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 625: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Single-center Experience with Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy in Infants with <36 Weeks' Gestation.

    Moran, Patricia / Sullivan, Kelsey / Zanelli, Santina A / Burnsed, Jennifer

    American journal of perinatology

    2024  

    Abstract: Objective:  Hypoxic-ischemic encephalopathy (HIE) is a leading cause of morbidity and mortality in neonates. Therapeutic hypothermia (TH) has improved outcomes and mortality in infants with >36 weeks' gestational age (GA) with moderate-to-severe HIE. ... ...

    Abstract Objective:  Hypoxic-ischemic encephalopathy (HIE) is a leading cause of morbidity and mortality in neonates. Therapeutic hypothermia (TH) has improved outcomes and mortality in infants with >36 weeks' gestational age (GA) with moderate-to-severe HIE. There are limited data on the safety and efficacy of TH in preterm infants with HIE. This study describes our experience and examines the safety of TH in neonates with <36 weeks' GA.
    Study design: A single-center, retrospective study of preterm neonates born at <36 weeks' GA with moderate-to-severe HIE and treated with TH, compared to a cohort of term neonates with HIE (≥37 weeks' GA), was conducted. The term cohort was matched for degree of background abnormality on electroencephalogram, sex, inborn versus outborn status, and birth year. Medical records were reviewed for pregnancy and delivery complications, need for transfusion, sedation and antiseizure medications, electroencephalography and imaging findings, and in-hospital mortality.
    Results:  Forty-two neonates born at <36 weeks' GA with HIE received TH between 2005 and 2022. Data from 42 term neonates were analyzed for comparison. The average GA of the preterm cohort was 34.6 weeks and 39.3 weeks for the term cohort. Apgar scores, degree of acidosis, and need for blood product transfusions were similar between groups. Preterm infants were more likely to require inotropic support (55 vs. 29%,
    Conclusion:  In this single-center cohort, TH in preterm infants appears to be as safe as in term infants, with no significant increase in intracranial bleeds or mortality. Preterm infants more frequently required inotropes and steroids for hypotension. Further research is needed to determine efficacy of TH in preterm infants.
    Key points: · TH is used off-protocol in preterm infants.. · Preterm and term infants have similar mortality.. · Preterm cohort required more inotropic support..
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/a-2251-6317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1929: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The positive and negative consequences of stress and its relationship with coping in medical students: A qualitative study.

    Manley, Amy Elizabeth / Biddle, Lucy / Savović, Jelena / Moran, Paul

    Medical teacher

    2024  , Page(s) 1–6

    Abstract: Rates of mental health problems among medical students have prompted efforts to reduce stress during medical training. However, stress can be motivating and is a feature of clinical work. This qualitative study explores what makes an experience stressful, ...

    Abstract Rates of mental health problems among medical students have prompted efforts to reduce stress during medical training. However, stress can be motivating and is a feature of clinical work. This qualitative study explores what makes an experience stressful, and how medical students respond to such experiences. In-depth interviews were conducted with a purposive sample of 15 medical students. Experiences were distressing when they threatened students' self-perception, goals or coping mechanisms, or when they reminded the student of distressing past events. Moderate stress was motivating and could build resilience. Students selected coping mechanisms based on their availability, acceptability, likely outcome and their previous experience of using these mechanisms. Social support, extra-curricular activities and exercise were helpful. High levels of distress, poor self-esteem and course factors, including remote placements, impaired engagement with coping strategies. Perception of stressors as being insurmountable or beyond one's control, led to increasing distress and the adoption of avoidant coping strategies. University strategies need to consider the beneficial effects of stress and seek to bolster coping resources as well as minimising unnecessary sources of stress.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 424426-6
    ISSN 1466-187X ; 0142-159X
    ISSN (online) 1466-187X
    ISSN 0142-159X
    DOI 10.1080/0142159X.2024.2333799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2176: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Minimally invasive laparoscopic transabdominal retrieval of dislocated trial femoral head prosthesis.

    Field, Michael / Sitzler, Paul / Moran, Peter / Kaplan, Elan

    BMJ case reports

    2023  Volume 16, Issue 12

    MeSH term(s) Humans ; Hip Prosthesis ; Arthroplasty, Replacement, Hip/adverse effects ; Joint Dislocations ; Prosthesis Design ; Treatment Outcome ; Prosthesis Failure ; Minimally Invasive Surgical Procedures
    Language English
    Publishing date 2023-12-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-256617
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Differentiated Epithelial Cells of the Gut.

    Bonilla-Díaz, Andrea / Ordóñez-Morán, Paloma

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2650, Page(s) 3–16

    Abstract: The intestine is a prime example of self-renewal where stem cells give rise to progenitor cells called transit-amplifying cells which differentiate into more specialized cells. There are two intestinal lineages: the absorptive (enterocytes and microfold ... ...

    Abstract The intestine is a prime example of self-renewal where stem cells give rise to progenitor cells called transit-amplifying cells which differentiate into more specialized cells. There are two intestinal lineages: the absorptive (enterocytes and microfold cells) and the secretory (Paneth cells, enteroendocrine, goblet cells, and tuft cells). Each of these differentiated cell types has a role in creating an "ecosystem" to maintain intestinal homeostasis. Here, we summarize the main roles of each cell type.
    MeSH term(s) Epithelial Cells ; Cell Differentiation ; Enterocytes ; M Cells ; Stem Cells
    Language English
    Publishing date 2023-06-13
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3076-1_1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Antisocial personality disorder

    Moran, Paul

    an epidemiological perspective

    1999  

    Author's details Paul Moran
    Keywords Abnorme Persönlichkeit ; Epidemiologie ; Psychiatrische Versorgung
    Subject Psychiatrie ; Psychopath ; Soziopath ; Krankheitsverbreitung
    Language English
    Size XVI, 125 S.
    Publisher Gaskell
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT011208441
    ISBN 1-901242-24-2 ; 0-88048-594-9 ; 978-1-901242-24-9 ; 978-0-88048-594-4
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2000 A 158 order for loan Magazin

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