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  1. Book ; Online: Cadenas de suministro global : Perspectiva desde la gestión de existencias

    Ernesto Barragán Moreno, Gabriel

    2019  

    Keywords Teachers' classroom resources & material ; Operational research ; Supply chain ; industrial administration ; logistics in business ; inventory control
    Size 1 electronic resource (122 pages)
    Publisher Editorial Uniagustiniana
    Document type Book ; Online
    Note Spanish ; Open Access
    HBZ-ID HT021232222
    ISBN 9789585498310 ; 9585498316
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Remdesivir-COVID-19: drug interactions in dentistry.

    Gómez-Moreno, G

    European review for medical and pharmacological sciences

    2020  Volume 24, Issue 18, Page(s) 9739–9743

    Abstract: Objective: Remdesivir is a nucleotide analogue prodrug that inhibits viral RNA polymerases. It has been recognized recently as a promising antiviral drug against a wide array of RNA viruses (including SARS/MERS-CoV5). We aimed at determining which drugs ...

    Abstract Objective: Remdesivir is a nucleotide analogue prodrug that inhibits viral RNA polymerases. It has been recognized recently as a promising antiviral drug against a wide array of RNA viruses (including SARS/MERS-CoV5). We aimed at determining which drugs used in dentistry interact with Remdesivir in order to avoid adverse reactions that may worsen the condition of patients with COVID-19.
    Materials and methods: A literature review was conducted to identify potential drug interactions between remdesivir (used in the treatment of COVID-19) and drugs prescribed in dentistry. The search was made in the databases PubMed and MEDLINE and official websites using key terms remdesivir, drug interactions and dentistry for articles published up to 31st July 2020.
    Results: According to the articles reviewed, a total of 279 drugs interact with Remdesivir. Two major interactions have been reported, 277 moderate drug interactions, and one with alcohol/food. The drug interactions involving drugs prescribed in dentistry are all moderate drug interactions and are (according to drug group): (1) antibiotics: azithromycin, clavulanate, doxycycline, erythromycin, levofloxacin; (2) antifungals: clotrimazole, fluconazole, itraconazole, ketoconazole; (3) non-steroidal anti-inflammatories (NAIDS): celecoxib diclofenac, etodolac, flurbiprofen, ibuprofen, ketoprofen, ketorolac, mefenamic acid, naproxen, piroxicam.
    Conclusions: It is clinically necessary for oral health professionals to be aware of possible drug interactions that may occur between remdesivir and drugs commonly prescribed in dentistry in order to prevent adverse reactions that may even endanger the life of a patient with COVID-19.
    MeSH term(s) Adenosine Monophosphate/adverse effects ; Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/therapeutic use ; Alanine/adverse effects ; Alanine/analogs & derivatives ; Alanine/therapeutic use ; Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/drug therapy ; Dentistry ; Drug Interactions ; Humans ; Pandemics ; Pneumonia, Viral/drug therapy ; SARS-CoV-2
    Chemical Substances Antiviral Agents ; remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Alanine (OF5P57N2ZX)
    Keywords covid19
    Language English
    Publishing date 2020-10-05
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202009_23065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Slice by slice: An Australian state-by-state analysis of Mohs micrographic surgery over 5 years.

    Farrell, Joshua / Moreno, Gilberto

    The Australasian journal of dermatology

    2023  Volume 64, Issue 4, Page(s) 497–503

    Abstract: Background: In November 2018, Mohs micrographic surgery (MMS) was restricted to fellows registered with the Australasian College of Dermatologists. Three new item numbers for the provision of MMS were also introduced. We examine the national and state ... ...

    Abstract Background: In November 2018, Mohs micrographic surgery (MMS) was restricted to fellows registered with the Australasian College of Dermatologists. Three new item numbers for the provision of MMS were also introduced. We examine the national and state usage of MMS item numbers based on Medicare claim statistics and Mohs surgeons' self-reported data, noting the impact of the pandemic and the usage of individual item numbers.
    Methods: Medicare item number data were obtained from the Medicare Benefits Schedule website for January 2017-December 2021. Self-reported data were collected on an annual basis by the Royal College of Pathologists of Australasia (RCPA) as part of the Quality Assurance Program (QAP) from 2019 onwards. Data were analysed with the Holt-Winters smoothing method for forecasting.
    Results: An increasing number of MMS claims were processed each year, with a total of 89,183 for the study period. Since November 2018, 97.7% of procedures have been conducted on the head, neck, genitalia, hand, digits, leg (below the knee) or foot. The provision of services across the country was maintained during the pandemic years of 2020-2021, with an increase in services in Queensland. There were discrepancies between the states for procedures performed in greater than six sections; these constituted more than 35% of claims in Queensland and Western Australia compared to less than 15% in other states. The pandemic impacted certain states more than others, with Victoria and the Northern Territory having significantly fewer presentations than predicted (p < 0.05).
    Conclusions: Overall, the use of MMS in Australia is in keeping with peer-developed guidelines, despite discrepancies between states. Although certain states were more severely affected by the pandemic, MMS is increasingly used in Australia.
    MeSH term(s) Aged ; Humans ; Mohs Surgery/methods ; Skin Neoplasms/surgery ; National Health Programs ; Neck ; Victoria
    Language English
    Publishing date 2023-08-24
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.14145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Empirical evidence of predictive adaptive response in humans: systematic review and meta-analysis of migrant populations.

    Bueno López, Clara / Gómez Moreno, Guillermo / Palloni, Alberto

    Journal of developmental origins of health and disease

    2024  Volume 14, Issue 6, Page(s) 728–745

    Abstract: Meta-analysis is used to test a variant of a Developmental Origins of Adult Health and Disease (DOHaD)'s conjecture known as predictive adaptive response (PAR). According to it, individuals who are exposed to mismatches between adverse or ... ...

    Abstract Meta-analysis is used to test a variant of a Developmental Origins of Adult Health and Disease (DOHaD)'s conjecture known as predictive adaptive response (PAR). According to it, individuals who are exposed to mismatches between adverse or constrained
    MeSH term(s) Adult ; Child ; Humans ; Overweight ; Diabetes Mellitus, Type 2/epidemiology ; Pediatric Obesity ; Transients and Migrants ; Hypertension/epidemiology
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2554780-X
    ISSN 2040-1752 ; 2040-1744
    ISSN (online) 2040-1752
    ISSN 2040-1744
    DOI 10.1017/S2040174423000429
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Remdesivir-COVID-19: drug interactions in dentistry

    Gómez-Moreno, G.

    Eur Rev Med Pharmacol Sci

    Abstract: OBJECTIVE: Remdesivir is a nucleotide analogue prodrug that inhibits viral RNA polymerases It has been recognized recently as a promising antiviral drug against a wide array of RNA viruses (including SARS/MERS-CoV5) We aimed at determining which drugs ... ...

    Abstract OBJECTIVE: Remdesivir is a nucleotide analogue prodrug that inhibits viral RNA polymerases It has been recognized recently as a promising antiviral drug against a wide array of RNA viruses (including SARS/MERS-CoV5) We aimed at determining which drugs used in dentistry interact with Remdesivir in order to avoid adverse reactions that may worsen the condition of patients with COVID-19 MATERIALS AND METHODS: A literature review was conducted to identify potential drug interactions between remdesivir (used in the treatment of COVID-19) and drugs prescribed in dentistry The search was made in the databases PubMed and MEDLINE and official websites using key terms remdesivir, drug interactions and dentistry for articles published up to 31st July 2020 RESULTS: According to the articles reviewed, a total of 279 drugs interact with Remdesivir Two major interactions have been reported, 277 moderate drug interactions, and one with alcohol/food The drug interactions involving drugs prescribed in dentistry are all moderate drug interactions and are (according to drug group): (1) antibiotics: azithromycin, clavulanate, doxycycline, erythromycin, levofloxacin;(2) antifungals: clotrimazole, fluconazole, itraconazole, ketoconazole;(3) non-steroidal anti-inflammatories (NAIDS): celecoxib diclofenac, etodolac, flurbiprofen, ibuprofen, ketoprofen, ketorolac, mefenamic acid, naproxen, piroxicam CONCLUSIONS: It is clinically necessary for oral health professionals to be aware of possible drug interactions that may occur between remdesivir and drugs commonly prescribed in dentistry in order to prevent adverse reactions that may even endanger the life of a patient with COVID-19
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #814893
    Database COVID19

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  6. Article ; Online: Sensing Enhancement on Social Networks: The Role of Network Topology.

    Brede, Markus / Romero-Moreno, Guillermo

    Entropy (Basel, Switzerland)

    2022  Volume 24, Issue 5

    Abstract: Sensing and processing information from dynamically changing environments is essential for the survival of animal collectives and the functioning of human society. In this context, previous work has shown that communication between networked agents with ... ...

    Abstract Sensing and processing information from dynamically changing environments is essential for the survival of animal collectives and the functioning of human society. In this context, previous work has shown that communication between networked agents with some preference towards adopting the majority opinion can enhance the quality of error-prone individual sensing from dynamic environments. In this paper, we compare the potential of different types of complex networks for such sensing enhancement. Numerical simulations on complex networks are complemented by a mean-field approach for limited connectivity that captures essential trends in dependencies. Our results show that, whilst bestowing advantages on a small group of agents, degree heterogeneity tends to impede overall sensing enhancement. In contrast, clustering and spatial structure play a more nuanced role depending on overall connectivity. We find that ring graphs exhibit superior enhancement for large connectivity and that random graphs outperform for small connectivity. Further exploring the role of clustering and path lengths in small-world models, we find that sensing enhancement tends to be boosted in the small-world regime.
    Language English
    Publishing date 2022-05-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e24050738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Antibiotics in development for multiresistant gram-negative bacilli.

    Rodríguez, A / Moreno, G / Bodi, M / Martín-Loeches, I

    Medicina intensiva

    2022  Volume 46, Issue 11, Page(s) 630–640

    Abstract: The rapid increase in antibiotic(ATB) resistance among Gram-negative bacilli(BGN), especially in strains of Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii, with high resistance patterns (XDR), poses a huge threat to health ... ...

    Abstract The rapid increase in antibiotic(ATB) resistance among Gram-negative bacilli(BGN), especially in strains of Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii, with high resistance patterns (XDR), poses a huge threat to health systems worldwide. In the last decade, different ATBs have been developed against XDR, some of which combine a lactam β along with a β-lactamase inhibitor, while others use non-β-lactam inhibitors. Most of them have adequate "in vitro" activity on several β-lactamases of class A, C and D of Ambler. However, combinations such as Ceftazidime/avibactam, Ceftolozane/Tazobactam and Meropenem/vaborbactam have no activity against metallo-β-lactamases(MβL). New combinations such as Aztreonan/AVI, Cefepime/Zidebactam, or new cephalosporins such as Cefiderocol, have efficacy against MβL enzymes. Although some of these combinations are already approved and in the commercialization phase, many of them have yet to define their place within the treatment of microorganisms with high resistance through clinical studies.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Gram-Negative Bacteria ; beta-Lactamase Inhibitors/pharmacology ; beta-Lactamase Inhibitors/therapeutic use ; beta-Lactamases ; Pseudomonas aeruginosa
    Chemical Substances Anti-Bacterial Agents ; beta-Lactamase Inhibitors ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2022-10-24
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2022.05.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pseudomembranous oral candidiasis resolved with a mouthwash containing 0.05% chlorhexidine + 0.05% cetylpyridinium chloride.

    Gómez-Moreno, G / Valerón-Rodríguez, F

    European review for medical and pharmacological sciences

    2021  Volume 25, Issue 18, Page(s) 5725–5728

    Abstract: A 50-year-old woman was referred to the clinic reporting oral discomfort during the previous month and plaques of a white removable slough. Diagnosis of pseudomembranous oral candidiasis was clinically confirmed. When the tongue and palatal mucosa were ... ...

    Abstract A 50-year-old woman was referred to the clinic reporting oral discomfort during the previous month and plaques of a white removable slough. Diagnosis of pseudomembranous oral candidiasis was clinically confirmed. When the tongue and palatal mucosa were wiped with gauze, the soft yellowish-white slough detached revealing the erythematous surface beneath. The patient also presented paranoid schizophrenia and severe depression, pulmonary emphysema, and two vertebral hernias. She was a smoker (10 cigarettes per day) with xerostomia that was being treated with: bupropion, reboxetine, quetiapine, trazadone clotiapine, pregabalin, fentanyl (patches), and alprazolam. To minimize the risk of potential drug interactions, a mouthwash containing 0.05% chlorhexidine + 0.05% cetylpyridinium chloride was prescribed three times a day for two weeks. At the end of the two weeks, the candidiasis had abated.
    MeSH term(s) Candidiasis, Oral/complications ; Candidiasis, Oral/drug therapy ; Candidiasis, Oral/pathology ; Cetylpyridinium/administration & dosage ; Chlorhexidine/administration & dosage ; Depression/complications ; Drug Interactions ; Female ; Humans ; Middle Aged ; Mouthwashes/administration & dosage ; Pulmonary Emphysema ; Schizophrenia/complications ; Treatment Outcome ; Xerostomia/complications
    Chemical Substances Mouthwashes ; Cetylpyridinium (CUB7JI0JV3) ; Chlorhexidine (R4KO0DY52L)
    Language English
    Publishing date 2021-09-28
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202109_26790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and male Zücker diabetic fatty rats.

    Salagre, D / Navarro-Alarcón, M / Villalón-Mir, M / Alcázar-Navarrete, B / Gómez-Moreno, G / Tamimi, F / Agil, A

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2024  Volume 172, Page(s) 116314

    Abstract: Melatonin acute treatment limits obesity of young Zücker diabetic fatty (ZDF) rats by non-shivering thermogenesis (NST). We recently showed melatonin chronically increases the oxidative status of vastus lateralis (VL) in both obese and lean adult male ... ...

    Abstract Melatonin acute treatment limits obesity of young Zücker diabetic fatty (ZDF) rats by non-shivering thermogenesis (NST). We recently showed melatonin chronically increases the oxidative status of vastus lateralis (VL) in both obese and lean adult male animals. The identification of VL skeletal muscle-based NST by uncoupling of sarcoendoplasmic reticulum Ca
    MeSH term(s) Female ; Male ; Animals ; Rats ; AMP-Activated Protein Kinases ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 ; Melatonin/pharmacology ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha ; Rats, Zucker ; Diabetes Mellitus, Experimental ; Organelle Biogenesis ; Muscle, Skeletal ; Obesity/drug therapy ; Muscle Proteins ; Proteolipids
    Chemical Substances sarcolipin (145018-73-1) ; AMP-Activated Protein Kinases (EC 2.7.11.31) ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 (EC 2.7.11.17) ; Melatonin (JL5DK93RCL) ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha ; Muscle Proteins ; Proteolipids
    Language English
    Publishing date 2024-02-22
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2024.116314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Corrigendum to "Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and male Zücker diabetic fatty rats" [Biomed. Pharmacother. 172 (2024) 116314].

    Salagre, D / Navarro-Alarcón, M / Villalón-Mir, M / Alcázar-Navarrete, B / Gómez-Moreno, G / Tamimi, F / Agil, A

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2024  Volume 173, Page(s) 116411

    Language English
    Publishing date 2024-03-07
    Publishing country France
    Document type Published Erratum
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2024.116411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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