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  1. Book ; Online: Weak Interactions in Molecular Machinery

    Díaz-Moreno, Irene / Isaacson, Rivka

    2019  

    Keywords Science: general issues ; weak interactions ; transient biointeractome ; NMR ; Biophysics ; molecular structure ; Proteins ; Nucleic Acids ; complexes
    Size 1 electronic resource (105 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231463
    ISBN 9782889457878 ; 2889457877
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Is it time to reconsider microbial health in ART?

    Moreno, I

    BJOG : an international journal of obstetrics and gynaecology

    2018  Volume 126, Issue 2, Page(s) 208

    MeSH term(s) Female ; Fertilization in Vitro ; Humans ; Microbiota ; Vaginosis, Bacterial
    Language English
    Publishing date 2018-04-15
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2000931-8
    ISSN 1471-0528 ; 0306-5456 ; 1470-0328
    ISSN (online) 1471-0528
    ISSN 0306-5456 ; 1470-0328
    DOI 10.1111/1471-0528.15219
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  3. Article ; Online: Planning the new phase of BioFactors: An IUBMB journal.

    Diaz-Moreno, Irene

    BioFactors (Oxford, England)

    2023  Volume 49, Issue 1, Page(s) 4–5

    Language English
    Publishing date 2023-01-31
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 59230-4
    ISSN 1872-8081 ; 0951-6433
    ISSN (online) 1872-8081
    ISSN 0951-6433
    DOI 10.1002/biof.1939
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  4. Article ; Online: LED irradiance pattern at short distances.

    Moreno, Ivan

    Applied optics

    2020  Volume 59, Issue 1, Page(s) 190–195

    Abstract: Many emerging light-emitting diode (LED) applications require short-distance illumination. For that, we derive an exact formula of the illumination profile produced by Lambertian LEDs, in which all parameters are fundamental constants. Moreover, we ... ...

    Abstract Many emerging light-emitting diode (LED) applications require short-distance illumination. For that, we derive an exact formula of the illumination profile produced by Lambertian LEDs, in which all parameters are fundamental constants. Moreover, we propose a general, simple, but accurate mathematical model of the irradiance pattern, valid for Lambertian and non-Lambertian LEDs at short distances. This model provides the irradiance profile as a function of both the LED-target distance and the coordinates of every point on the irradiated surface. The model is formulated in terms of simple sigmoid functions, in which LED size and light flux are fundamental parameters. The accuracy of the irradiance pattern model is tested both with theory and with experimental measurements.
    Language English
    Publishing date 2020-03-26
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.59.000190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Dual polarization Fourier transform processor using geometric-phase lenses.

    García-Martínez, Pascuala / Moreno, Ignacio

    Optics express

    2023  Volume 31, Issue 10, Page(s) 16460–16470

    Abstract: This work presents a novel optical system for polarization image processing using geometric-phase (Pancharatnam-Berry) lenses. Such lenses are half-wave plates where the orientation of the fast (slow) axis follows a quadratic relation with the radial ... ...

    Abstract This work presents a novel optical system for polarization image processing using geometric-phase (Pancharatnam-Berry) lenses. Such lenses are half-wave plates where the orientation of the fast (slow) axis follows a quadratic relation with the radial coordinate, and they present the same focal length but opposite sign for left and right circular polarizations. Therefore, they split an input collimated beam in a converging beam and a diverging beam with opposite circular polarizations. This coaxial polarization selectivity introduces a new degree of freedom in optical processing systems and makes it interesting for imaging and filtering applications that require polarization sensitivity. Here we profit from these properties to build an optical Fourier filter system with polarization sensitivity. A telescopic system is used to have access to two real Fourier transform planes, one for each circular polarization. A second symmetric optical system is used to recombine the two beams onto a single final image. As a result, polarization sensitive optical Fourier filtering can be applied, as demonstrated with simple bandpass filters.
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.490093
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  6. Article ; Online: Vestibulotoxicity in Patients Undergoing Cisplatin-Based Cancer Treatment: A Phase IIIB Randomized Controlled Clinical Trial.

    Moreno, Inmaculada / Belinchon, Antonio

    Audiology & neuro-otology

    2023  Volume 28, Issue 3, Page(s) 230–238

    Abstract: Introduction: This study aimed to evaluate the incidence of balance disorders and the efficacy of dexamethasone in protecting patients undergoing cisplatin-based cancer treatment against vestibulototoxicity.: Methods: This study was a randomized ... ...

    Abstract Introduction: This study aimed to evaluate the incidence of balance disorders and the efficacy of dexamethasone in protecting patients undergoing cisplatin-based cancer treatment against vestibulototoxicity.
    Methods: This study was a randomized controlled phase IIIB clinical trial. The subjects participating in the clinical trial were patients with a neoplastic disease whose treatment protocol included cisplatin. The average dose of cisplatin was 444.87 mg (SD 235.2 mg). Treatment consisted of intratympanically administering dexamethasone via a passive diffusion device called Microwick (8 mg/24 h dose) from the start of treatment with cisplatin to 3 weeks after the last cycle. Patients were administered the medication to one ear, and the contralateral ear was used as the control. The treated ears were randomly chosen using a computer system (randomization). Vestibular system was evaluated by video head impulse test before each cisplatin cycle.
    Results: Thirty-four patients were recruited over a 2-year period at a reference tertiary hospital, of whom 11 were excluded. Forty-six ears were analyzed (23 treated and 23 control ears). Vestibular analysis presented no changes in the mean increase in the vestibulo-ocular response in all patients evaluated, both in treated and control ears. Both 8.69% infection complications during treatment and 34.8% permanent perforation at 6 months were detected after device removal.
    Conclusion: Ototoxicity related to cisplatin-based treatment does not affect the vestibular system. Long-term high-dose intratympanic dexamethasone treatment is safe for the vestibular system.
    MeSH term(s) Humans ; Cisplatin/adverse effects ; Antineoplastic Agents/adverse effects ; Dexamethasone/adverse effects ; Neoplasms/drug therapy
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Antineoplastic Agents ; Dexamethasone (7S5I7G3JQL)
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Clinical Trial, Phase III ; Journal Article
    ZDB-ID 1314086-3
    ISSN 1421-9700 ; 1420-3030
    ISSN (online) 1421-9700
    ISSN 1420-3030
    DOI 10.1159/000528435
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    Zs.A 4518: Show issues Location:
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  7. Article ; Online: Unveiling Invariant Optical Properties of Dielectric Meta-Atoms.

    Basilio-Ortiz, J Carlos / Moreno, Ivan

    Nano letters

    2024  

    Abstract: The phase-shift, transmittance, and polarization properties of meta-atoms are investigated, motivated by their use as building blocks of metasurfaces used in metalenses, holograms, and beam shaping. We studied dielectric nanorod meta-atoms of several ... ...

    Abstract The phase-shift, transmittance, and polarization properties of meta-atoms are investigated, motivated by their use as building blocks of metasurfaces used in metalenses, holograms, and beam shaping. We studied dielectric nanorod meta-atoms of several geometries, which included cylinders, triangles, squares, hexagons, octagons, and truncated cones. By analyzing light propagation through these meta-atoms for three different wavelengths (632.8, 545, and 50 nm), we show that the phase-shift introduced is independent of their cross-section shape, contrary to the expected behavior. Additionally, we show that the polarization response is independent of the shape and that the transmittance is partially shape-independent. We identify a novel dependence of phase-shift on the effective cross-sectional area of meta-atoms. These meta-atom optical properties are independent of its shape if its geometry has a C3 or larger rotational symmetry. This optical invariance has significant implications for the topological optimization of flat optics.
    Language English
    Publishing date 2024-04-11
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.4c00742
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  8. Article ; Online: Deciphering the role of Zn

    Corrales-Guerrero, Laura / Díaz-Moreno, Irene

    BioFactors (Oxford, England)

    2024  

    Abstract: T-cell intracellular antigen-1 (TIA-1) is a key RNA-binding protein that participates in translation regulation and RNA splicing. TIA-1 undergoes liquid-liquid phase separation as a fundamental mechanism that enables the condensation of RNA and proteins ... ...

    Abstract T-cell intracellular antigen-1 (TIA-1) is a key RNA-binding protein that participates in translation regulation and RNA splicing. TIA-1 undergoes liquid-liquid phase separation as a fundamental mechanism that enables the condensation of RNA and proteins into membraneless organelles called stress granules (SGs). However, this dynamic behavior can lead to aberrant fibril formation, implicated in neurodegenerative disorders, and must be tightly regulated. In this study, we investigated the role in the cell of histidine residues His94 and His96, responsible for Zn
    Language English
    Publishing date 2024-01-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 59230-4
    ISSN 1872-8081 ; 0951-6433
    ISSN (online) 1872-8081
    ISSN 0951-6433
    DOI 10.1002/biof.2037
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  9. Article ; Online: Influence of abiotic factors on diapause termination and temperature requirements for postdiapause development in the European red mite, Panonychus ulmi (Acari: Tetranychidae).

    Martínez-Villar, E / López-Manzanares, B / Legarrea, S / Pérez-Moreno, I / Marco-Mancebón, V S

    Experimental & applied acarology

    2024  Volume 92, Issue 4, Page(s) 777–794

    Abstract: The European red mite Panonychus ulmi (Koch) is widely distributed and it can severely affect pome fruit crops, particularly apple. Pest outbreaks are related to an overuse of non-selective pesticide treatments that lead to the development of resistance ... ...

    Abstract The European red mite Panonychus ulmi (Koch) is widely distributed and it can severely affect pome fruit crops, particularly apple. Pest outbreaks are related to an overuse of non-selective pesticide treatments that lead to the development of resistance and the absence of natural enemies in the orchard. A key aspect to optimize the use of pesticide treatments in the context of IPM is to increase the knowledge on the biology and ecology of the pest to better predict population dynamics and outbreaks. For the European red mite, knowledge on the conditions that lead to diapause breaking by winter eggs is essential to model population dynamics. To increase this knowledge, winter eggs were collected during field surveys in northen Spain during three years and egg hatching was monitored under controlled temperature and photoperiod conditions in the laboratory. The "number of days exposed to cold temperatures" was the most significant factor that positively affected hatching of overwintering eggs. The time required for 50% of the egg population to hatch (T
    MeSH term(s) Animals ; Tetranychidae/physiology ; Tetranychidae/growth & development ; Diapause ; Ovum/growth & development ; Ovum/physiology ; Temperature ; Spain ; Photoperiod ; Cold Temperature ; Female ; Seasons
    Language English
    Publishing date 2024-04-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 11320-7
    ISSN 1572-9702 ; 0168-8162
    ISSN (online) 1572-9702
    ISSN 0168-8162
    DOI 10.1007/s10493-024-00904-9
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  10. Article ; Online: Higiene de manos y pandemia. Controversias.

    Fernández-Moreno, I / García-Díez, R / Vázquez-Calatayud, M

    Enfermeria intensiva

    2022  Volume 33, Page(s) S40–S44

    Abstract: During the COVID-19 pandemic, the world's healthcare systems were extremely strained. Intensive care units were stretched to capacity and healthcare facilities were forced to set up spaces to care for critically ill patients. Professionals were required ... ...

    Title translation Hand hygiene and pandemic. Controversies.
    Abstract During the COVID-19 pandemic, the world's healthcare systems were extremely strained. Intensive care units were stretched to capacity and healthcare facilities were forced to set up spaces to care for critically ill patients. Professionals were required to work in strenuous conditions, completely disrupting their work routines.In this scenario, hand hygiene and the use of gloves by healthcare professionals became a critical point of transmission risk.The results of the ENVIN study in 2020 and 2021, corresponding to the pandemic period, showed worrying data on the increase in infection rates, with rates rising by 250% at the worst moments of the pandemic. This suggested that excessive risk situations were occurring for the patient. Any preventive strategy must place correct hand hygiene and proper use of gloves among its priority objectives. For this reason, the Project Zero Advisory Board made a series of adaptations and recommendations based on available evidence and expert opinion related to hand hygiene and glove use during the pandemic situation to promote best practice in extreme situations. This article reviews the key aspects of hand hygiene as part of the WHO safety strategy, the main barriers to compliance and the main adaptations proposed by the Advisory Board of the Zero projects.
    Language Spanish
    Publishing date 2022-07-23
    Publishing country Spain
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 2018901-1
    ISSN 1578-1291 ; 1130-2399
    ISSN (online) 1578-1291
    ISSN 1130-2399
    DOI 10.1016/j.enfi.2022.06.003
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